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您的检索式：作者名="Yumeng Zhan"
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| 1 | CaMKIIα-driven,phosphatase-checked postsynaptic plasticity via phase separation显示文摘Ca^(2+)/calmodulin-dependent kinase Ila(CaMKIla)is essential for synaptic plasticity and learning by decoding synaptic Ca^(2+)oscillations.Despite decades of extensive research,new mechanisms underlying CaMKIIa's function in synapses are still being discovered.Here,we discover that Shank3 is a specific binding partner for autoinhibited CaMKIla.We demonstrate that Shank3 and GluN2B,via combined actions of Ca^(2+)and phosphatases,reciprocally bind to CaMKIla.Under basal condition,CaMKIla is recruited to the Shank3 subcompartment of postsynaptic density(PSD)via phase separation.Rise of Ca^(2+)concentration induces GluN2Bmediated recruitment of active CaMKIla and formation of the CaMKIIa/GluN2B/PSD-95 condensates,which are autonomously dispersed upon Ca^(2+)removal.Protein phosphatases control the Ca^(2+)-dependent shuttling of CaMKIla between the two PSD subcompartme nts and PSD condensate formation.Activation of CaMKIla further enlarges the PSD assembly and in duces structural LTP.Thus,Ca^(2+)-induced and phosphatase-checked shuttling of CaMKIla between distinct PSD nano-domains can regulate phase separation-mediated PSD assembly and synaptic plasticity. | Qixu Caic Menglong Zeng Xiandeng Wu Haowei Wu Yumeng Zhan Ruijun Tian Mingjie Zhang | 2021 | Cell Research2021，31，1： | 3 |
| 2 | Construction of a novel ZnCo_2O_4/Bi_2O_3 heterojunction photocatalyst with enhanced visible light photocatalytic activity显示文摘A novel ZnCo_2O_4/Bi_2O_3 heterojunction photocatalyst was prepared, and the formation of the heterojunction was confirmed via HRTEM. Photocatalytic activity of as-prepared samples was evaluated through photodegradation of malachite green(MG). The degradation results show that the as-prepared13% ZnCo_2O_4/Bi_2O_3 heterojunction photocatalyst exhibits higher activity than pure Bi_2O_3. The MG degradation rate for the as-prepared catalyst is as high as 94%. The enhanced photocatalytic activity is mainly attributed to the broad photoabsorption and low recombination rate of photogenerated electronhole pairs, which is driven by the photogene rated potential difference formed at the ZnCo_2O_4/Bi_2O_3 heterojunction interface. | Jun Chen Jing Zhan Yumeng Zhang Yiwei Tang | 2019 | Chinese Chemical Letters2019，30，3： | 2 |
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