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| 1 | Graphene-carbon nanotube hybrid films for high- performance flexible photodetectors显示文摘Graphene 活跃地为灵活、可拉长的设备作为候选人材料正在被探索。然而,基于 graphene 的灵活 photonic 设备的发展,即光电探测器,被碳原子的单个层的低吸收度妨碍。最近,货车 der Waals 结合了碳 nanotube 和 graphene 混血儿电影证明了像静脉的碳 nanotube 网络的优秀 photoresponsivity,和使用导致了显著地更高的机械力量。这里,我们第一次报导,有 51 A/W 和快回答 ~ 预定的 ~ 的高 photoresponsivity 的一个灵活光电探测器在可见范围上的 40 ms,揭示这个新兴的所有碳混血儿的唯一的潜力为灵活设备拍摄。另外,设备对重复弯曲展出好坚韧性,建议它在大区域的矩阵数组的适用性灵活光电探测器。 | Yujie Liu Yuanda Liu Shuchao Qin Yongbing Xu Rong Zhang Fengqiu Wang | 2017 | Nano Research2017，10，6： | 7 |
| 2 | Late Holocene hydroclimatic variations and possible forcing mechanisms over the eastern Central Asia显示文摘Hydroclimatic variations over the eastern Central Asia are highly sensitive to changes in hemispheric-scale atmospheric circulation systems. To fully understand the long-term variability and relationship between hydroclimate and atmospheric circulation system, we present a high-resolution lascustrine record of late Holocene hydroclimate from Lake Sayram, Central Tianshan Mountains, China, based on the total organic carbon, total nitrogen, and carbonate contents, carbon/nitrogen ratios, and grain size. Our results reveal four periods of substantially increased precipitation at the interval of 4000–3780, 3590–3210, 2800–2160, and 890–280 cal yr BP, and one period of slightly increased precipitation from 1700–1370 cal yr BP. These wetter periods broadly coincide with those identified in other records from the mid-latitude Westerlies-dominated eastern Central Asia, including the northern Tibetan Plateau. As such, a similar hydroclimatic pattern existed over this entire region during the late Holocene. Based on a close similarity of our record with reconstruction of North Atlantic Oscillation indices and solar irradiance, we propose that decreased solar irradiance and southern migration of the entire circum-North Atlantic circulation system, particularly the main pathway of the mid-latitude Westerlies, significantly influenced hydroclimate in eastern Central Asia during the late Holocene. Finally, the inferred precipitation at Lake Sayram has increased markedly over the past 100 years, although this potential future changes in hydroclimate in Central Asia need for further investigation. | Jianghu LAN Hai XU Keke YU Enguo SHENG Kangen ZHOU Tianli WANG YuANDa YE Dongna YAN Huixian WU Peng CHENG Waili ABULIEZI Liangcheng TAN | 2019 | Science China Earth Sciences2019，62，8： | 3 |
| 3 | Doctors’Dilemma in Auspicious Pulse Diagnosis Represented in Ming-Qing Fiction显示文摘Auspicious pulse diagnosis/pregnancy diagnosis in traditional Chinese medicine involves such issues as medical skills,narrative skills,family decency,and ethics.It is an excellent case for the exploration of ethical dilemmas in traditional Chinese medical practice.The early classical medical texts such as Su Wen(Basic Questions)and Ling Shu Jing(Spiritual Pivot Canon)provide a principle-based ethical guide for doctor-patient communication,while popular fiction such as Hong Lou Meng(A Dream of Red Mansions),Yu Mu Xing Xin Bian(Stories:Entertain to Enlighten),and Feng Yue Meng(Courtesans and Opium)in the Ming and Qing dynasties present literary examples for solving ethical dilemmas.This article will analyze these texts from three perspectives.First,the doctors in the text were subject to gender order and other delicate etiquette and customs,therefore were unable to make the diagnosis without embarrassing the patients and jeopardizing family decency.Second,the narrator tends to attribute pregnancy misdiagnosis to three reasons:incomplete patient information,doctors’poor narrative competence,and doctors’corrupted medical ethics.Finally,the Ming-Qing fiction proposes three methods to solve this moral dilemma:clear pulse reading,tactful speech,and taboo challenging.This discussion of moral dilemmas in pregnancy diagnosis in traditional Chinese medical practice can be used as a reference for the localization of narrative medicine. | LI Yuanda MAO Xu | 2023 | Chinese Medicine and Culture2023，6，2： | 1 |
| 4 | White Electroluminescence with Simultaneous Three-Color Emission from a Four-Armed Star-Shaped Single-Polymer System显示文摘有4,7二度的一个四手臂的塑造星的单个聚合物的系统(5-(4-( 9H-carbazol-9-yl )苯基) -4-hexylthiophen-2-yl)benzo[c][1,2,5]thiadiazole ( FTBT )作为一个红放射性的核心, polyfluorene ( PF )作为绿放射性的掺杂物作为蓝放射性的手臂和 1,3-benzo thiadiazole ( BT )被设计并且综合,在里面哪个红,绿,并且蓝色(红绿蓝)排放平衡能被小心地调整 FTBT 和 BT 的做的集中完成。一台典型 single-emissive-layer 设备(ITO/PEDOT : PSS/polymer/TPBI/LiF/Al ) 被学习并且讨论,与 1.59 cd·A −1 和 CIE 的发光效率(LE ) 认识到纯、稳定的白排出物协调(0.31, 0.34 ) 。设备的 high-color-quality 白人 electroluminescence 能主要从蓝 PF 手臂被归因于压制的分子间的相互作用,和部分精力转移到红、绿的掺杂物。 | Yuanda Jiu Jianyun Wang Chengfang Liu Wenyong Lai Lingling Zhao Xiangchun Li Yi Jiang Weidong Xu Xinwen Zhang Wei Huang | 2015 | Chinese Journal of Chemistry2015，33，8： | 1 |
| 5 | Concomitant chemoradiotherapy using pemetrexed and carboplatin for unresectable stage III non-small cell lung cancer (NSCLC): Preliminary results of a phase II study显示文摘 | Yaping Xu Shenglin Ma Yongling Ji Xiaojiang Sun Hao Jiang Jianxiang Chen Xianghui Du Yuanda Zheng Guoqin Qiu | 2010 | Lung Cancer2010，，3： | 1 |
| 6 | Oncolytic adenoviruses expressing checkpoint inhibitors for cancer therapy显示文摘Despite the remarkable success of immune checkpoint inhibitors(ICIs),primary resistance to ICIs causes only subsets of patients to achieve durable responses due to the complex tumor microenvironment(TME).Oncolytic viruses(OVs)can overcome the immunosuppressive TME and promote systemic antitumor immunity in hosts.Engineered OVs armed with ICIs would likely have improved effectiveness as a cancer therapy.According to the diverse immune cell landscapes among different types of tumors,we rationally and precisely generated three recombinant oncolytic adenoviruses(OAds):OAd-SIRPα-Fc,OAd-Siglec10-Fc and OAd-TIGIT-Fc.These viruses were designed to locally deliver SIRPα-Fc,Siglec10-Fc or TIGIT-Fc fusion proteins recognizing CD47,CD24 or CD155,respectively,in the TME to achieve enhanced antitumor effects.Our results suggested that OAd-SIRPα-Fc and OAd-Siglec10-Fc both showed outstanding efficacy in tumor suppression of macrophage-dominated tumors,while OAd-TIGIT-Fc showed the best antitumor immunity in CD8+T-cell-dominated tumors.Importantly,the recombinant OAds activated an inflammatory immune response and generated long-term antitumor memory.In addition,the combination of OAd-Siglec10-Fc with anti-PD-1 significantly enhanced the antitumor effect in a 4T1 tumor model by remodeling the TME.In summary,rationally designed OAds expressing ICIs tailored to the immune cell landscape in the TME can precisely achieve tumor-specific immunotherapy of cancer. | Daoyuan Xie Yaomei Tian Die Hu Yuanda Wang Yuling Yang Bailing Zhou Rui Zhang Zhixiang Ren Mohan Liu Jie Xu Chunyan Dong Binyan Zhao Li Yang | 2023 | Signal Transduction and Targeted Therapy2023，8，12： | 0 |
| 7 | Venovenous extracorporeal membrane oxygenation for COVID-19 and influenza H1N1 associated acute respiratory distress syndrome:A comparative cohort study in China显示文摘Background Venovenous extracorporeal membrane oxygenation(VV-ECMO)has been demonstrated to be effective in treating patients with virus-induced acute respiratory distress syndrome(ARDS).However,whether the management of ECMO is different in treating H1N1 influenza and coronavirus disease 2019(COVID-19)-associated ARDS patients remains unknown.Methods This is a retrospective cohort study.We included 12 VV-ECMO-supported COVID-19 patients admitted to The First Affiliated Hospital of Guangzhou Medical University,Guangzhou Eighth People's Hospital,and Wuhan Union Hospital West Campus between January 23 and March 31,2020.We retrospectively included VV-ECMO-supported patients with COVID-19 and H1N1 influenza-associated ARDS.Clinical characteristics,respiratory mechanics including plateau pressure,driving pressure,mechanical power,ventilatory ratio(VR)and lung compliance,and outcomes were compared.Results Data from 25 patients with COVID-19(n=12)and H1N1(n=13)associated ARDS who had received ECMO support were analyzed.COVID-19 patients were older than H1N1 influenza patients(P=0.004).The partial pressure of arterial carbon dioxide(PaCO_(2))and VR before ECMO initiation were significantly higher in COVID-19 patients than in H1N1 influenza patients(P<0.001 and P=0.004,respectively).COVID-19 patients showed increased plateau and driving pressure compared with H1N1 subjects(P=0.013 and P=0.018,respectively).Patients with COVID-19 remained longer on ECMO support than did H1N1 influenza patients(P=0.015).COVID-19 patients who required ECMO support also had fewer intensive care unit and ventilator-free days than H1N1.Conclusions Compared with H1N1 influenza patients,COVID-19 patients were older and presented with increased PaCO_(2) and VR values before ECMO initiation.The differences between ARDS patients with COVID-19 and influenza on VV-ECMO detailed herein could be helpful for obtaining a better understanding of COVID-19 and for better clinical management. | Yonghao Xu Yin Xi Shuijiang Cai Yuheng Yu Sibei Chen Weijie Guan Weibo Liang Hongkai Wu Weiqun He Xilong Deng Yuanda Xu Rong Zhang Manshu Li Jieyi Pan Zhenting Liang Ya Wang Shaofeng Kong Xiaoqing Liu Zheng Lv Yimin Li | 2023 | Journal of Intensive Medicine2023，3，4： | 0 |
| 8 | Study on Two-phase Nanocrystalline Nd_(8.5)Fe_(74)Co_5Cu_1Nb_1Zr_3Cr_1B_(6.5)Permanent Magnet显示文摘Nd8.5Fe74Co5Cu1Nb1Zr3Cr1B6.5 bonded magnets were prepared by melt-spun and subsequent heat treatment. Magnetic properties of Br=0.68T, JHc=716 kA/m, (BH)max=77 kJ/m^3 were achieved. The addition of Cr element shows to be significantly advantageous in reducing grain size and increasing the intrinsic coercivity. | Jiansen NI, Hui XU, Mingyuan ZHU, Qiang LI, Bangxin ZHOU and Yuanda DONGInstitute of Materials, Shanghai University, Shanghai 200072, China | 2004 | Journal of Materials Science & Technology2004，20，2： | 0 |
| 9 | All-carbon hybrids for high-performance electronics,optoelectronics and energy storage显示文摘The family of carbon allotropes such as carbon nanotubes(CNTs) and graphene, with their rich chemical and physical characteristics, has attracted intense attentions in the field of nanotechnology and enabled a number of disruptive devices and applications in electronics, optoelectronics and energy storage.Just as no individual 2 D(two-dimensional) material can meet all technological requirements of various applications, combining carbon materials of different dimensionality into a hybrid form is a promising strategy to optimize properties and to build novel devices operating with new principles. In particular, the direct synthesis of 2 D or 3 D(three-dimensional) sp2-hybridized all-carbon hybrids based on merging CNTs and graphene affords a great promise for future electronic, optoelectronic and energy storages. Here, we review the progress of all-carbon hybrids-based devices, covering material preparation, fabrication techniques as well as applied devices. Recent progress about large-scale synthesis and assembly techniques is highlighted,and with many intrinsic advantages, the all-carbon strategy opens up a highly promising approach to obtain high-performance integrated circuits. Moreover, this review will discuss the remaining challenges in the field and provide perspectives on future applications. | Shuchao QIN Yuanda LIU Hongzhu JIANG Yongbing XU Yi SHI Rong ZHANG Fengqiu WANG | 2019 | Science China(Information Sciences)2019，62，12： | 0 |
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