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| 1 | IL-23 signaling enhances Th2 polarization and regulates allergic airway inflammation显示文摘 | Juan Peng Xuexian O Yang Seon Hee Chang Jiong Yang Chen Dong | 2010 | Cell Research2010，20，1： | 31 |
| 2 | 高级别(WHO G3)胰腺神经内分泌肿瘤分类中形态学和生物学的异质性:包括分化好和分化差的肿瘤显示文摘WHO(2010)分类推荐胰腺神经内分泌肿瘤(PanNETs)的分级建立在核分裂象和Ki-67增殖指数的基础上,2级(G2)PanNETs定义为核分裂象2~20个/10HPF或Ki-67增殖指数在3%~20%之间,3级(G3)胰腺神经内分泌癌(NEC)定义为核分裂象〉20个/10HPF或Ki-67增殖指数〉20%。 | Basturk O Yang Z Tang L H 魏建国 许春伟 邰艳红 | 2015 | 临床与实验病理学杂志2015，31，4： | 25 |
| 3 | Effect of intestinal ischemia-reperfusion on expressions of endogenous basic fibroblast growth factor and transforming growth factor β in lung and its relation with lung repair显示文摘AIM To study the changes of endogenoustransforming growth factor β(TGFβ)and basicfibroblast growth factor(bFGF)in lung followingintestinal ischemia and reperfusion injury andtheir effects on lung injury and repair.METHODS Sixty Wistar rats were divided intofive groups,which underwent sham-operation,ischemia(45 minutes),and reperfusion(6,24and 48 hours,respectively)after ischemia(45minutes).Immunohistochemical method wasused to observe the localization and amounts ofboth growth factors.RESULTS Positive signals of both growthfactors could be found in normal lung,mainly inalveolar cells and endothelial cells of vein.Afterischemia and reperfusion insult,expressions ofboth growth factors were increased and theiramounts at 6 hours were larger than those ofnormal control or of 24 and 48 hours after insult.CONCLUSION The endogenous bFGF and TGF βexpression appears to be up-regulated in thelung following intestinal ischemia andreperfusion,suggesting that both growth factorsmay be involved in the process of lung injury andrepair. | Xiao Bing Fu Yin Hui Yang Tong Zhu Sun Xiao Man Gu Li Xian Jiang Xiao Oing Sun Zhi Yong Sheng Research Laboratory,304th Hospital of PLA,Beijing 100037,China | 2000 | World Journal of Gastroenterology2000，6，3： | 21 |
| 4 | 肾管状囊性癌临床病理和分子特征显示文摘 | Yang X J Zhou M Hes O 张仁亚(摘译) | 2008 | 临床与实验病理学杂志2008，24，1： | 13 |
| 5 | Genetic lineage tracing identifies in situ Kit-expressing cardiomyocytes显示文摘 | Qiaozhen Liu Rui Yang Xiuzhen Huang Hui Zhang Lingjuan He Libo Zhang Xueying Tian Yu Nie Shengshou Hu Yan Yan Li Zhang Zengyong Qiao Qing-Dong Wang Kathy O Lui Bin Zhou | 2016 | Cell Research2016，26，1： | 12 |
| 6 | GURTIN VARIATIONAL PRINCIPLE AND FINITE ELEMENT SIMULATION FOR DYNAMICAL PROBLEMS OF FLUID-SATURATED POROUS MEDIA显示文摘Based on the theory of porous media,a general Gurtin variational principle for theinitial boundary value problem of dynamical response of fluid-saturated elastic porous media isdeveloped by assuming infinitesimal deformation and incompressible constituents of the solid andfluid phase.The finite element formulation based on this variational principle is also derived.Asthe functional of the variational principle is a spatial integral of the convolution formulation,thegeneral finite element discretization in space results in symmetrical differential-integral equationsin the time domain.In some situations,the differential-integral equations can be reduced to sym-metrical differential equations and,as a numerical example,it is employed to analyze the reflectionof one-dimensional longitudinal wave in a fluid-saturated porous solid.The numerical results canprovide further understanding of the wave propagation in porous media. | Yang Xiao Cheng Changjun Department o,f Mechanics, Shanghai Institute of Applied Mathematics and Mechanics,Shanghai University,Shanghai 200436,China) | 2003 | Acta Mechanica Solida Sinica2003，16，1： | 10 |
| 7 | 肾脏的小管状囊性癌:临床病理和分子学特征显示文摘 | Yang X J Zhou M Hes O 黄文斌(摘译) | 2008 | 临床与实验病理学杂志2008，24，3： | 9 |
| 8 | Treatment and prognosis of hepatic epithelioid hemangioendothelioma based on SEER data analysis from 1973 to 2014显示文摘Background: Hepatic epithelioid hemangioendothelioma (HEH) is a rare tumor of vascular origin with an unknown etiology, a low incidence, and a variable natural course. We evaluated the management and prognosis of HEH from the Surveillance, Epidemiology and End Results (SEER) program and changes in treatment modalities of HEH over 30 years. Methods: From 1973 to 2014 in the SEER database, we selected patients diagnosed with HEH. We analyzed the clinical characteristics, patterns of management, and clinical outcomes of patients with HEH. Results: We identi ed 79 patients with HEH (median age: 54.0 years;male to female ratio: 1:2.6). The initial extent of disease was local in 22 (27.8%) patients, regional metastasis in 22 (27.8%), distant metas-tasis in 31 (39.2%) and unknown in 4 (5.1%). The median size of primary tumor was 3.85 cm (interquartile range, 2.50 7.93 cm). Among 74 patients with available management data, the most common manage-ment was no treatment (29/74, 39.2%), followed by chemotherapy only (22/74, 29.7%), liver resection-based (13/74, 17.6%), and transplantation-based therapy (6/74, 8.1%). The 5-year cancer-speci c survival rate was 57.8%. Patients who underwent surgical treatment had signi cantly higher survival than those who underwent non-surgical treatment (5-year survival;88% vs. 49%, P=0.019). Multivariate analysis revealed that surgical therapy was the only independent prognostic factor for survival (hazard ratio: 0.20, P=0.040). Conclusions: Resection or liver transplantation is worth considering for treatment of patients with HEH. | O Kyu Noh Soon Sun Kim Min Jae Yang Sun Gyo Lim Jae Chul Hwang Hyo Jung Cho Jae Youn Cheong Sung Won Cho | 2020 | Hepatobiliary & Pancreatic Diseases International2020，19，1： | 7 |
| 9 | Improvement on Mixograph test through water addition and parameter conversions显示文摘To improve Mixograph testing effect, Farinograph measurements were adopted as a quality standard and changes in water absorption and parameter conversion in Mixograph test were explored. Comparative study showed that increasing water absorption to about 73% and converting original parameters to compound parameters in Mixograph tests significantly increased their predictive power for flour quality. These efforts also enabled the adoption of fixed water addition level in Mixograph test and simplified the test procedure significantly. With the success in parameter conversions, Mixograph test results were successfully described by Farinograph parameters, which allow breeders to compare and exchange test results easily. All these changes optimized the official method of Mixograph test with simplified procedure and enhanced reliability and made the Mixograph being the superior tool for quality assessment in wheat-breeding programs. | SUN Jia-zhu YANG Wen-long LIU Dong-cheng ZHAO Jun-tao LUO Guang-bin LI Xin LIU Yan-jun GU O Jin-kao ZHANG Ai-min | 2015 | Journal of Integrative Agriculture2015，14，9： | 6 |
| 10 | The experimental study of genetic engineering human neural stem cells mediated by lentivirus to express multigene显示文摘 | Cai PQ Tang X Lin YQ Martin O Sun GY Xu L Yang YK Zhou TH | 2006 | 中国生物学文摘2006，20，5： | 6 |
| 11 | Sonohysterography: Principles, technique and role in diagnosis of endometrial pathology显示文摘Sonohysterography (SHG), which provides enhanced endometrial visualization during standard transvaginal ultrasonography, is a relatively safe procedure for the evaluation of endometrial pathology. It can be used to evaluate patients with abnormal vaginal bleeding or infertility. This modality offers real time imaging of the endometrium without exposure to ionizing radiation. SHG is typically used in patients for whom standard transvaginal ultrasonography does not show the endometrium well, show a potential abnormality for which further imaging is required, or in patients without endometrial pathology defined on routine transvaginal imaging but in whom there is a strong clinical suspicion of an abnormality. This article will discuss the utility of the sonohysterogram in evaluation of various endometrial pathologies. Imaging examples of these pathological entities will be illustrated as well. | Thomas Yang Amit Pandya Leonardo Marcal Ronald O Bude Joel F Platt Deepak G Bedi Khaled M Elsayes | 2013 | World Journal of Radiology2013，5，3： | 5 |
| 12 | Safety of endovascular therapy for symptomatic intracranial artery stenosis:a national prospective registry显示文摘Introduction The safety outcomes of endovascular therapy for intracranial artery stenosis in a real-world stetting are largely unknown.The Clinical Registration Trial of Intracranial Stenting for Patients with Symptomatic Intracranial Artery Stenosis(CRTICAS)was a prospective,multicentre,real-world registry designed to assess these outcomes and the impact of centre experience.Methods 1140 severe,symptomatic intracranial arterial stenosis(ICAS)patients treated with endovascular therapy were included from 26 centres,further divided into three groups according to the annual centre volume of intracranial angioplasty and stent placement procedures over 2 years:(1)high volume for≥25 cases/year;(2)moderate volume for 10–25 cases/year and(3)low volume for<10 cases/year.Results The rate of 30-day stroke,transient ischaemic attack or death was 9.7%(111),with 5.4%,21.1%and 9.7%in high-volume,moderate-volume and low-volume centres,respectively(p<0.05).Multivariable logistic regression confirmed high-volume centres had a significantly lower primary endpoint compared with moderate-volume centres(OR=0.187,95%CI:0.056 to 0.627;p≤0.0001),while moderate-volume and low-volume centres showed no significant difference(p=0.8456).Conclusion Compared with the preceding randomised controlled trials,this real-world,prospective,multicentre registry shows a lower complication rate of endovascular treatment for symptomatic ICAS.Non-uniform utilisation in endovascular technology,institutional experience and patient selection in different volumes of centres may have an impact on overall safety of this treatment. | Yabing Wang Tao Wang Adam Andrew Dmytriw Kun Yang Liqun Jiao Huaizhang Shi Jie Lu Tianxiao Li Yujie Huang Zhenwei Zhao Wei Wu Jieqing Wan Qinjian Sun Bo Hong Yongli Li Liyong Zhang Jianfeng Chu Qiong Cheng Yiling Cai Pengfei Wang Qi Luo Hua Yang Baijing Dong Yang Zhang Jun Zhao Zuoquan Chen Wei Li Xiaoxin Bai Weiwen He Xueli Cai Maimai Ti Osama O Zaidat | 2022 | Stroke & Vascular Neurology2022，7，2： | 3 |
| 13 | Extracting typical occupancy schedules from social media (TOSSM) and its integration with building energy modeling显示文摘Building occupancy,one of the most important consequences of occupant behaviors,is a driving influencer for building energy consumption and has been receiving increasing attention in the building energy modeling community.With the vast development of information technologies in the era of the internet-of-things,occupant sensing and data acquisition are not limited to a single node or traditional approaches.The prevalence of social networks provides a myriad of publically available social media data that might contain occupancy information in the space for a given time.In this paper,we explore two approaches to extract the typical occupancy schedules for the input to the building energy simulation based on the data from social networks.The first approach uses text classification algorithms to identify whether people are present in the space where they are posting on social media.On top of that,the typical building occupancy schedules are extracted with assumed people counting rules.The second approach utilizes the processed Global Positioning System(GPS)tracking data provided by social networking service companies such as Facebook and Google Maps.Web scraping techniques are used to obtain and post-process the raw data to extract the typical building occupancy schedules.The results show that the extracted building occupancy schedules from different data sources(Twitter,Facebook,and Google Maps)share a similar trend but are slightly distinct from each other and hence may require further validation and corrections.To further demonstrate the application of the extracted Typical Occupancy Schedules from Social Media(TOSSM),data-driven models for predicting hourly energy usage prediction of a university museum are developed with the integration of TOSSM.The results indicate that the incorporation of TOSSM could improve the hourly energy usage prediction accuracy to a small extent regarding the four adopted evaluation metrics for this museum building. | Xing Lu Fan Feng Zhihong Pang Tao Yang Zheng O’Neill | 2021 | Building Simulation2021，14，1： | 3 |
| 14 | Oligomeric Procyanidins Induce Generation of Reactive Oxygen Species and Collapse of Mitochchondrial Membrane Potential in Glioblastoma Cell Lines显示文摘Objective The aim of the present study was to clarify the mechanism underlying glioma cell death upon oligomeric procyanidins (F2) exposure. Methods The cytotoxicity of F2 on U87 (human malignant glioblastoma cell line) and C6 (rat glioma cell line) cancer cells was evaluated, and changes of mitochondrial membrane potential (MMP) and production of reactive oxygen species (ROS) in drug-treated cells were monitored. Moreover, morphological changes associated with F2-induced cells death were examined. Results F2 induced a concentration-dependent increase in ROS production and decrease in MMP. Furthermore, pre-incubation with N-acetylcysteine (NAC) and rotenone (Rt), resulted in partial inhibition of F2-induced ROS generation and marked attenuation of cell death and the cytoplasmic vacuolization induced by F2. In addition, pretreatment with Rt markedly attenuated the MMP loss in F2-treated cells. However, pretreatment with NAC only markedly attenuated the MMP loss in F2-treated C6 cells. Conclusion The increase in ROS level is at least one of mechanisms associated with F2-induced glioma cell death as well as the cytoplasmic vacuolization formation that contribute to the cytotoxicity of F2 in glioma cells. | ZHANG Feng-jiao1, YANG Jing-yu1, MOU Yan-hua1, SUN Bao-shan2, WANG Ji-ming3, WANG Fang1, WU Chun-fu1 1. Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang 110016, China 2. Estaco Vitivinícola Nacional, Instituto National de Investigaco Agrária, Dois Portos 2565-191, Portugal 3. Laboratory of Molecular Immunoregulation, Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute at Frederick, Frederick Maryland 21702, USA | 2009 | Chinese Herbal Medicines2009，1，1： | 3 |
| 15 | Will advanced lithiumalloy anodes have a chance in lithium-ion batteries 显示文摘 | BESENHARD J O YANG J WINTER M | 1997 | J Power Sources1997，68，： | 2 |
| 16 | BRAF and KRAS Mutations in Hyperplastic Polyps and Serrated Adenomas of the Colorectum: Relationship to Histology and CpG Island Methylation Status显示文摘 | Shi Yang Francis A Farraye Charline Mack Oksana Posnik Michael J O’Brien | 2004 | The American Journal of Surgical Pathology2004，，11： | 2 |
| 17 | The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase显示文摘 | Thomas F Franke Sung-Il Yang Tung O Chan Ketaki Datta Andrius Kazlauskas Deborah K Morrison David R Kaplan Philip N Tsichlis | 1995 | Cell1995，，5： | 2 |
| 18 | Selenocysteine tRNAs as Central Components of Selenoprotein Biosynthesis in Eukaryotes显示文摘Selenocysteine (Sec) tRNAs serve as carrier molecules for the biosynthesis of Sec from serine and to donate Sec to protein in response to specific UGA codons. In this study, we describe the current status of Sec tRNAs in higher animals and further we exarnine: (i) the Sec tRNA population in Drosophila; (ii) transcription of the Sec tRNA in vivo (in Xenopus oocytes) and in vitro (in Xenopus oocyte extracts); (iii) the effect of selenium on the Sec tRNA population in various rat tissues following replenishment of extremely selenium deficient rats with this element; and (iv) the biosynthesis of the modified bases on Sec tRNA in Xenopus | SANG ICK PARK JIN Mo PARK HAROLD S. CHITTUM EUN SUNG YANG BRADLEY A. CARLSON BYEONG JAE LEE AND DOLPH L. HATFIELD(Laboratory of Experimental Chrcinogenesis, National Cancer Insti tute, National Institutes of Health, Bethesda, MD 20892USA Laboratory o | 1997 | Biomedical and Environmental Sciences1997，10，2： | 2 |
| 19 | From occupants to occupants:A review of the occupant information understanding for building HVAC occupant-centric control显示文摘Occupants are the core of the built environment.Traditional heating,ventilation,and air-conditioning(HVAC)systems operate with predefined schedules and maximum occupancy assumptions with no consideration of specific occupant information.These generalized assumptions usually do not align with the actual demand and result in over-conditioning and occupant discomfort.In recent years,with the aid of Information&Communication Technology(ICT)and Computer Science(CS),it is possible to acquire real-time and accurate occupant information to satisfy the exact thermal requirement through specific HVAC control in one particular built environment.This mechanism is called HVAC“Occupant-centric Control(OCC).”HVAC OCC strategy starts with collecting the occupant’s information(e.g.,presence/absence)and then applies it to meet the occupant’s requirement(e.g.,thermal comfort).However,even though some research studies and field pilot demonstrations have been devoted to the field of OCC,there is a lack of systematic knowledge about occupant data,which is the principal component of OCC for HVAC researchers and practitioners.To fill this gap,this review paper discusses OCC with a particular emphasis on occupant information and investigates how this information can assist HVAC operation in providing an acceptable built environment in required spaces during the required time.We provide a fine-grained,comprehensive picture of occupant information,discuss its features,the modalities of information feed-in into the HVAC control,and the application of commonly utilized occupant information for OCC. | Tao Yang Arkasama Bandyopadhyay Zheng O’Neill Jin Wen Bing Dong | 2022 | Building Simulation2022，15，6： | 2 |
| 20 | Ethylene biosynthesis: identification of 1-aminocyclopropane-1-carboxylic acid as an intermediate in the conversion of methionine to ethylene 显示文摘 | Adams D O Yang S F | 1979 | Proc Natl Acad Sci1979，76，1： | 2 |
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