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| 1 | A nowcasting model for the prediction of typhoon tracks based on a long short term memory neural network显示文摘It is of vital importance to reduce injuries and economic losses by accurate forecasts of typhoon tracks. A huge amount of typhoon observations have been accumulated by the meteorological department, however, they are yet to be adequately utilized. It is an effective method to employ machine learning to perform forecasts. A long short term memory(LSTM) neural network is trained based on the typhoon observations during 1949–2011 in China's Mainland, combined with big data and data mining technologies, and a forecast model based on machine learning for the prediction of typhoon tracks is developed. The results show that the employed algorithm produces desirable 6–24 h nowcasting of typhoon tracks with an improved precision. | GAO Song ZHAO Peng PAN Bin LI Yaru ZHOU Min XU Jiangling ZHONG Shan SHI Zhenwei | 2018 | Acta Oceanologica Sinica2018，37，5： | 17 |
| 2 | Response of grain yield to plant density and nitrogen rate in spring maize hybrids released from 1970 to 2010 in Northeast China显示文摘The objective of this study was to identify the response of grain yield to plant density and nitrogen rate in spring maize hybrids released from 1970 to 2010 and grown extensively in Northeast China.Twenty-one hybrids were grown for 2 years in Northeast China at densities of 30,000,52,500,75,000,and 97,500 plants ha^(-1)and N application levels of 0,150,300,and 450 kg N ha^(-1).Irrespective of density or nitrogen application rate,grain yields both per plant and per unit area were significantly higher for newer than older hybrids.As plant density increased from 30,000 to 97,500 plant ha^(-1),yield per plant of 1970 s,1980 s,1990 s,and 2000 s hybrids decreased by 50%,45%,46%,and 52%,respectively.The response of grain yield per unit area to plant density was curvilinear.The estimated optimum plant densities were about 58,000,49,000,65,000,and 65,000 plants ha^(-1)for hybrids released in the 1970 s,1980s,1990 s,and 2000 s,respectively.The theoretical optimum densities for the hybrids released from the 1970 s to the 2000 s increased by 1750 plants ha^(-1)decade^(-1).Nitrogen fertilization significantly increased grain yields per plant and per unit area for all hybrids.The theoretical optimum N application rates for high yield for hybrids released in the 1970 s and 1980 s were about 280 and 360 kg ha^(-1),and the hybrids from the 1990 s and 2000 s showed highest yield at 330 kg ha^(-1)N.No significant difference in the grain yields of 2000 s hybrids between the N levels of 150 to 450 kg ha^(-1)was found.Significant yield gains per plant and per unit area were found,with average increases of 17.9 g plant^(-1)decade^(-1)and936 kg ha^(-1)decade^(-1)over the period 1970–2010,respectively.Yield gains were attributed mainly to increased yield per plant,contributed by increases in kernel number per ear and1000-kernel weight.The rates of lodging and barren plants of newer hybrids were significantly lower than those of older ones,especially at high plant density. | Chunrong Qian Yang Yu Xiujie Gong Yubo Jiang Yang Zhao Zhongliang Yang Yubo Hao Liang Li Zhenwei Song Weijian Zhang | 2016 | The Crop Journal2016，4，6： | 15 |
| 3 | Less than 6 GHz resolution THz spectroscopy of water vapor显示文摘在许多的技术象石油工业一样回答的兆兆赫(THz ) 的申请要求高分辨率和多功能认识到不同材料的精确察觉。在这学习水里,在空气的蒸汽与 shortand 被扫描有不同扫描范围的长路径的 THz 分光计。在在长路径的系统的 THz 典型的线的半最大值的完整的宽度到达了不到 7 GHz 和那在突然完成了 5.5 GHz,显示水蒸汽的 THz 光谱学能被用来校准 THz 设备。有正确扫描范围的 THz 系统能是为有由于高分辨率的很类似的结构的固体,液体和气体的材料的鉴定的一种有希望的选择。研究证明多功能的 THz 测试能在许多领域里通过分辨率和采样空格的平衡被认识到,例如油气体工业。 | ZHAN HongLei SUN ShiNing ZHAO Kun LENG WenXiu BAO RiMa XIAO LiZhi ZHANG ZhenWei | 2015 | Science China(Technological Sciences)2015，58，12： | 10 |
| 4 | Non-destructive detection of pigments in oil painting by using terahertz tomography显示文摘Dear Editors,Terahertz technology has been applied in many fields[1–3].The protection and restoration of historical relics and cultural heritage,which is a new application area of terahertz technology,have been attracting much attention recently[4,5]because of its social significance and market prospects.The most important premise is to obtain information of the cultural relics without damaging them again.Therefore the appropriate non-destructively testing methods are | ZHANG ZhenWei WANG KeJia LEI Yong ZHANG ZhuoYong ZHANG ZhenWei WANG KeJia LEI Yong ZHANG ZhuoYong ZHAO YuanMeng LI ChenYu GU An SHI NingChang ZHAO Kun ZHAN HongLei ZHANG CunLin | 2015 | Science China(Physics,Mechanics & Astronomy)2015，58，12： | 8 |
| 5 | Nuclear Aurora kinase A switches m^(6)A reader YTHDC1 to enhance an oncogenic RNA splicing of tumor suppressor RBM4显示文摘Aberrant RNA splicing produces alternative isoforms of genes to facilitate tumor progression,yet how this process is regulated by oncogenic signal remains largely unknown.Here,we unveil that non-canonical activation of nuclear AURKA promotes an oncogenic RNA splicing of tumor suppressor RBM4 directed by m^(6)A reader YTHDC1 in lung cancer.Nuclear translocation of AURKA is a prerequisite for RNA aberrant splicing,specifically triggering RBM4 splicing from the full isoform(RBM4-FL)to the short isoform(RBM4-S)in a kinase-independent manner. | SiSi Li YangFan Qi JiaChuan Yu YuChao Hao Bin He MengJuan Zhang ZhenWei Dai TongHui Jiang SuYi Li Fang Huang Ning Chen Jing Wang MengYing Yang DaPeng Liang Fan An JinYao Zhao WenJun Fan YuJia Pan ZiQian Deng YuanYuan Luo Tao Guo Fei Peng ZhiJie Hou ChunLi Wang FeiMeng Zheng LingZhi Xu Jie Xu QingPing Wen BiLian Jin Yang Wang Quentin Liu | 2022 | Signal Transduction and Targeted Therapy2022，7，5： | 4 |
| 6 | LncDACH1 promotes mitochondrial oxidative stress of cardiomyocytes by interacting with sirtuin3 and aggravates diabetic cardiomyopathy显示文摘Diabetic cardiomyopathy(DCM)is a common complication in diabetic patients.The molecular mechanisms of DCM remain to be fully elucidated.The intronic long noncoding RNA of DACH1(lnc DACH1)has been demonstrated to be closely associated with heart failure and cardiac regeneration.In this study,we investigated the role of lnc DACH1 in DCM and the underlying molecular mechanisms.The expression of lnc DACH1 was increased in DCM hearts and in high glucose-treated cardiomyocytes.Knockout of lnc DACH1 reduced mitochondrial oxidative stress,cell apoptosis,cardiac fibrosis and hypertrophy,and improved cardiac function in DCM mice.Overexpression of lnc DACH1 exacerbated mitochondria-derived reactive oxygen species(ROS)level and apoptosis,decreased activity of manganese superoxide dismutase(Mn-SOD);while silencing of lnc DACH1 attenuated ROS production,mitochondrial dysfunction,cell apoptosis,and increased the activity of Mn-SOD in cardiomyocytes treated with high glucose.Lnc DACH1 directly bound to sirtuin3(SIRT3)and facilitated its degradation by ubiquitination,therefore promoting mitochondrial oxidative injury and cell apoptosis in mouse hearts.In addition,SIRT3 silencing abrogated the protective effects of lnc DACH1 deficiency in cardiomyocytes.In summary,lnc DACH1 aggravates DCM by promoting mitochondrial oxidative stress and cell apoptosis via increasing ubiquitination-mediated SIRT3 degradation in mouse hearts.Inhibition of lnc DACH1 represents a novel therapeutic strategy for the intervention of diabetic cardiomyopathy. | Qi Zhang Danyang Li Xue Dong Xiaowen Zhang Junwu Liu Lili Peng Bo Meng Qi Hua Xinyu Pei Lu Zhao Xiaoxi Hu Yang Zhang Zhenwei Pan Yanjie Lu Baofeng Yang | 2022 | Science China(Life Sciences)2022，65，6： | 4 |
| 7 | Voltage-induced penetration effect in liquid metals at room temperature显示文摘Room-temperature liquid metal is discovered to be capable of penetrating through macro-and microporous materials by applying a voltage.The liquid metal penetration effects are demonstrated in various porous materials such as tissue paper;thick and fine sponges;fabrics;and meshes.The underlying mechanism is that the high surface tension of liquid metal can be significantly reduced to near-zero due to the voltage-induced oxidation of the liquid metal surface in a solution.It is the extremely low surface tension and gravity that cause the liquid metal to superwet the solid surface^leading to the penetration phenomena.These findings offer new opportunities for novel microfluidic applications and could promote further discovery of more exotic fluid states of liquid metals. | Frank F Yun Zhenwei Yu Yahua He Lei Jiang Zhao Wang Haoshuang Gu Xiaolin Wang | 2020 | National Science Review2020，7，2： | 3 |
| 8 | Safety of endovascular therapy for symptomatic intracranial artery stenosis:a national prospective registry显示文摘Introduction The safety outcomes of endovascular therapy for intracranial artery stenosis in a real-world stetting are largely unknown.The Clinical Registration Trial of Intracranial Stenting for Patients with Symptomatic Intracranial Artery Stenosis(CRTICAS)was a prospective,multicentre,real-world registry designed to assess these outcomes and the impact of centre experience.Methods 1140 severe,symptomatic intracranial arterial stenosis(ICAS)patients treated with endovascular therapy were included from 26 centres,further divided into three groups according to the annual centre volume of intracranial angioplasty and stent placement procedures over 2 years:(1)high volume for≥25 cases/year;(2)moderate volume for 10–25 cases/year and(3)low volume for<10 cases/year.Results The rate of 30-day stroke,transient ischaemic attack or death was 9.7%(111),with 5.4%,21.1%and 9.7%in high-volume,moderate-volume and low-volume centres,respectively(p<0.05).Multivariable logistic regression confirmed high-volume centres had a significantly lower primary endpoint compared with moderate-volume centres(OR=0.187,95%CI:0.056 to 0.627;p≤0.0001),while moderate-volume and low-volume centres showed no significant difference(p=0.8456).Conclusion Compared with the preceding randomised controlled trials,this real-world,prospective,multicentre registry shows a lower complication rate of endovascular treatment for symptomatic ICAS.Non-uniform utilisation in endovascular technology,institutional experience and patient selection in different volumes of centres may have an impact on overall safety of this treatment. | Yabing Wang Tao Wang Adam Andrew Dmytriw Kun Yang Liqun Jiao Huaizhang Shi Jie Lu Tianxiao Li Yujie Huang Zhenwei Zhao Wei Wu Jieqing Wan Qinjian Sun Bo Hong Yongli Li Liyong Zhang Jianfeng Chu Qiong Cheng Yiling Cai Pengfei Wang Qi Luo Hua Yang Baijing Dong Yang Zhang Jun Zhao Zuoquan Chen Wei Li Xiaoxin Bai Weiwen He Xueli Cai Maimai Ti Osama O Zaidat | 2022 | Stroke & Vascular Neurology2022，7，2： | 3 |
| 9 | Acetytation of ACAP4 regutates CCL18-elicited breast cancer cell migration and invasion显示文摘Tumor metastasis represents the main causes of cancer-related death.Our recent study showed that chemokine CCL18 secreted from tumor-associated macrophages regulates breast tumor metastasis,but the underlying mechanisms remain less clear.Here, we show that ARF6 GTPase-activating protein ACAP4 regulates CCL18-elicited breast cancer cell migration via the acetyltransferase PCAF-mediated acetylation.CCL18 stimulation elicited breast cancer cell migration and invasion via PCAF-dependent acetylation.ACAP4 physically interacts with PCAF and is a cognate substrate of PCAF during CCL18 stimulation.The acetylation site of ACAP4 by PCAF was mapped to Lys311 by mass spectrometric analyses.Importantly,dynamic acetylation of ACAP4 is essential for CCL18-induced breast cancer cell migration and invasion,as overexpression of the persistent acetylation-mimicking or nonacetylatable ACAP4 mutant blocked CCL18-elicited cell migration and invasion.Mechanistically,the acetylation of ACAP4 at Lys311 reduced the lipid-binding activity of ACAP4 to ensure a robust and dynamic cycling of ARF6-ACAP4 complex with plasma membrane in response to CCL18 stimulation.Thus,these results present a previously undefined mechanism by which CCL18-elicited acetylation of the PH domain controls dynamic interaction between ACAP4 and plasma membrane during breast cancer cell migration and invasion. | Xiaoyu Song Wei Liu Xiao Yuan Jiying Jiang Wanjuan Wang McKay Mullen Xuannv Zhao Yin Zhang Fusheng Liu Shihao Du Adeel Rehman Ruijun Tian Jian Li Andra Frost Zhenwei Song Hadiyah-Nicole Green Calmour Henry Xing Liu Xia Ding Dongmei Wang Xuebiao Yao | 2018 | Journal of Molecular Cell Biology2018，10，6： | 3 |
| 10 | Optimum design of grain impact sensor utilising polyvinylidene fluoride films and a floating raft damping structure显示文摘 | Zhao Zhan Li Yaoming Liang Zhenwei | | 0，，03： | 1 |
| 11 | A randomized, multi-central, controlled study of patients with hepatitis B e antigen-positive chronic hepatitis B treated by adefovir dipivoxil or adefovir dipivoxil plus bicyclol显示文摘 | Wen Xie Guangfeng Shi Hongfei Zhang Guiming Zhao Zujiang Yu Zhenwei Lang Hong Zhao Jie Yan Jun Cheng | 2012 | Hepatology International2012，，2： | 1 |
| 12 | A seepage-stress coupled analysis of seabed deformation induced by the decomposition of gas hydrate显示文摘 | Zhenwei zhao Xinchun shang | 2011 | Intemafional Journal Computational Science and Engineering2011，6，4： | 1 |
| 13 | Thermal Decomposition Reaction and a Comprehensive Kinetic Model of Dimethyl Ether显示文摘 | ZHAO Zhenwei Chaos M Kazakov A | 2008 | International Journal of Chemical Kinetics2008，40，1： | 1 |
| 14 | Analysis of Propagation and Polarization Characteristics of Electromagnetic Waves Through Nonuniform Magnetized Plasma Slab Using Propagator Matrix Method显示文摘 | Yin X Zhang Hou Zhao Zhenwei | 2013 | Progress in Electromagnetics Research2013，137，： | 1 |
| 15 | A Comprehensive Kinetic Mechanism for CO, CH2O, and CH3OH Combustion 显示文摘 | Li Juan Zhao Zhenwei Kazakov A | 2007 | International Journal of Chemical Kinetics2007，39，3： | 1 |
| 16 | A comprehensive kinetic mechanism for CO, CH2O, and CH3OH combustion 显示文摘 | Juan Li Zhenwei Zhao Andrei Kazakov | 2007 | International Journal of Chemical Kinetics2007，39，3： | 1 |
| 17 | An updated comprehensive kinetic model of hydrogen combustion显示文摘 | Li Jun Zhao Zhenwei Kazakov Andrei | 2004 | International Journal of Chemical Kinetics2004，36，： | 1 |
| 18 | An Up- dated Comprehensive Kinetic Model of Hydrogen Com- bustion 显示文摘 | LI Juan ZHAO Zhenwei Kazakov A | 2004 | International Journal of Chemical Kinetics2004，36，10： | 1 |
| 19 | Millimeter-wave attenuation due to fog and clouds 显示文摘 | Zhao Zhenwei Wu Zhensen | 2000 | International Journal of Infrared and Millimeter Waves2000，21，1： | 1 |
| 20 | Optimum design of grain impact sensor utilizing polyvinylidene fluoride films and a floating raft damping structure显示文摘 | Zhao Zhan Li Yaoming Liang Zhenwei | 2012 | Biosystems Engineering2012，112，3： | 1 |
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