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| 1 | The RppC-AvrRppC NLR-effector interaction mediates the resistance to southern corn rust in maize显示文摘Southern corn rust(SCR),caused by the fungal pathogen Puccinia polysora,is a major threat to maize pro-duction worldwide.Efficient breeding and deployment of resistant hybrids are key to achieving durable control of SCR.Here,we report the molecular cloning and characterization of RppC,which encodes an NLR-type immune receptor and is responsible for a major SCR resistance quantitative trait locus.Further-more,we identified the corresponding avirulence effector,AvrRppC,which is secreted by P.polysora and triggers RppC-mediated resistance.Allelic variation of AvrRppC directly determines the effectiveness of RppC-mediated resistance,indicating that monitoring of AvrRppC variants in the field can guide the rational deployment of RppC-containing hybrids in maize production.Currently,RppC is the most frequently deployed SCR resistance gene in China,and a better understanding of its mode of action is crit-ical for extending its durability. | Ce Deng April Leonard James Cahill Meng Lv Yurong Li Shawn Thatcher Xueying Li Xiaodi Zhao Wenjie Du Zheng Li Huimin Li Victor Llaca Kevin Fengler Lisa Marshall Charlotte Harris Girma Tabor Zhimin Li Zhiqiang Tian Qinghua Yang Yanhui Chen Jihua Tang Xintao Wang Junjie Hao Jianbing Yan Zhibing Lai Xiaohong Fei Weibin Song Jinsheng Lai Xuecai Zhang Guoping Shu Yibo Wang Yuxiao Chang Weiling Zhu Wei Xiong Juan Sun Bailin Li Junqiang Ding | 2022 | Molecular Plant2022，15，5： | 6 |
| 2 | Lipid-dependent conformational dynamics underlie the functional versatility of T-cell receptor显示文摘T 房间 receptor-CD3 建筑群(TCR ) 是能基于 CD3 细胞质的领域的各种各样的生物化学的变化开始抗原特定的有免疫力的回答的一台万用的发信号机器,但是内在的结构的基础留下逃犯。这里,我们开发了生物物理的途径学习 CD3 细胞质的领域的 conformational 动力学(CD3 CD ) 。在单个分子的水平,我们发现那 CD3 CD 能与三个功能的主题的不同坦诚有多重 conformational 状态,即, ITAM, BRS 和 PRS。因为,这些符合构造被产生 CD3 CD 有异构的类脂化合物绑定性质因此有异构的动力学。实时房间的成像实验证明不同抗原刺激能稳定 CD3 在不同符合构造的 CD 。类脂化合物依赖者 conformational 动力学因此为 TCR 的万用的发信号性质提供结构的基础。 | Xingdong Guo Chengsong Yan Hua Li Wenmao Huan Xiaoshan Shi Min Huang Yingfang Wang Weiling Pan Mingjun Cai Lunyi Li Wei Wu Yibing Bai Chi Zhang Zhijun Liu Xinyan Wang Xiaohui F Zhang Chun Tang Hongda Wang Wanli Liu Bo Ouyang Catherine C Wong Yi Cao Chenqi Xu | 2017 | Cell Research2017，27，4： | 5 |
| 3 | Optimizing synthesis conditions of nanoscale zero-valent iron (nZVI) through aqueous reactivity assessment显示文摘Nanoscale 铁粒子(nZVI ) 最重要的设计 nanomaterials 之一被用于环境污染控制和消退。尽管大量的合成途径被建议了,屏蔽候选人 nZVI 材料的反应的一个灵巧的方法生产了使用不同方法或在变化下面,合成条件还被建立了。在这研究,四个反应参数在减少 borohydride 的 nZVI 的准备被调整。结果的 nanoparticles 的减少的性质用二个模型独立地是 assayed 水的沾染物, Cu (II ) 和硝酸盐。结果证实 nZVI 的减少的反应对铁先锋的起始的集中很敏感, borohydride 在粒子合成期间喂率,和 borohydride 的装载比率到铁的离子。相反,答案混合速度在 nZVI 的反应上带相对小重量。二探查的反应(即, Cu (II ) 和硝酸盐减小) 能关于 nZVI 的使团正常化的表面活动产生一致、量的推理。然而,硝酸盐试金是有效的在冲淡水的答案仅仅(50 mgL 1 或更低) 由于在提高的硝酸盐集中的铁表面的加速的释放。包括 nZVI 的结构、化学的化妆的另外的卓见能从 Cu (II ) 减小评价被积累。在这研究调查的反应试金能便于候选人材料或 nZVI 生产参数的优化屏蔽,它补充一些在 nZVI 研究使用的更复杂却不太化学上特定的材料描述方法。 | Yanlai HAN Michael D. Y. YANG Weixian ZHANG Weile YAN | 2015 | Frontiers of Environmental Science & Engineering2015，9，5： | 2 |
| 4 | Application of fluorescence in situ hybridization in the detection of bladder transitional-cell carcinoma: A multi-center clinical study based on Chinese population显示文摘Objective:To evaluate the diagnostic value of fluorescence in situ hybridization(FISH)in bladder cancer.Methods:We enrolled healthy volunteers and patients who were clinically suspected to have bladder cancer and conducted FISH tests and cytology examinations from August 2007 to December 2008.Receiver operating characteristic(ROC)curve analysis was performed and the area under curve(AUC)values were calculated for both the FISH and urine cytology tests.Results:A cohort of 988 healthy volunteers was enrolled to establish a reference range for the normal population.A total of 4807 patients with hematuria were prospectively,randomly enrolled for the simultaneous analysis of urine cytology,FISH testing,and a final diagnosis as determined by the pathologic findings of a biopsy or a surgically-excised specimen.Overall,the sensitivity of FISH in detecting transitional-cell carcinoma was 82.7%,while that of cytology was 33.4%(p<0.001).The sensitivity values of FISH for non-muscle invasive and muscle invasive bladder transitional-cell carcinoma were 81.7%and 89.6%,respectively(p=0.004).The sensitivity values of FISH for low and high grade bladder cancer were 82.6%and 90.1%,respectively(p=0.002).Conclusion:FISH is significantly more sensitive than voided urine cytology for detecting bladder cancer in patients evaluated for gross hematuria at all cancer grades and stages.Higher sensitivity using FISH was obtained in high grade and muscle invasive tumors. | Liqun Zhou Kaiwei Yang Xuesong Li Yi Ding Dawei Mu Hanzhong Li Yong Yan Jinyi Li Dongwen Wang Wei Li Yulong Cong Jiangping Gao Kewei Ma Yajun Xiao Sheng Zhang Hongyi Jiang Weilie Hu Qiang Wei Xunbo Jin Zhichen Guan Qingyong Liu Danfeng Xu Xin Gao Yongguang Jiang Weimin Gan Guang Sun Qing Wang Yanhui Liu Jianquan Hou Liping Xie Xishuang Song Fengshuo Jin Jiafu Feng Ming Cai Zhaozhao Liang Jie Zhang Dingwei Ye Lin Qi Lulin Ma Jianzhong Shou Yuping Dai Jianyong Shao Ye Tian Shizhe Hong Tao Xu Chuize Kong Zefeng Kang Yuexin Liu Xun Qu Benkang Shi Shaobin Zheng Yi Lin Shujie Xia Dong Wei Jianbo Wu Weiling Fu Zhiping Wang Jianbo Liang | 2019 | Asian Journal of Urology2019，6，1： | 2 |
| 5 | Simultaneous oxidation and reduction of arsenic by zero-valent iron nanoparticles: Understanding the significance of the core-shell structure显示文摘 | Ramos Mauricio A V Yan Weile Li Xiaoqin | 2009 | Journal of Physical Chemistry C2009，113，33： | 1 |
| 6 | Mesoporous carbon nanosheet-assembled flowers towards superior potassium storage显示文摘Potassium-ion batteries(PIBs)are attracted tremendous interest for large-scale energy storage systems(ESSs)owing to their economic merits.However,the main challenges of the PIBs are sluggish K-ion diffusion and large volume variations in the potassium repeated intercalation/deintercalation.Herein,mesoporous carbon nanosheet-assembled flowers(abbreviated as F-C)are designed as an original anode for superior-performance PIBs.Specifically,the F-C anode exhibits a high K-storage capacity(e.g.,381 mAh/g at 50 mA/g during the 2^(nd)cycle),excellent rate performance(e.g.,101 mAh/g at 2.0 A/g)and superior long cycle capability.Such excellent K-ion storage property is largely benefited from the large surface area(~141 m^(2)/g)and reasonable pore volume(0.465 cm^(3)/g),which not only stimulates rapid Kions diffusion and relieves the huge volume strain,but also exposes extensive active sites for K-ion capacitive storage. | Xianghua Zhang Dong Chen Yanping Zhou Dan Yang Weiling Liu Yuezhan Feng Xianhong Rui Yan Yu | 2021 | Chinese Chemical Letters2021，32，3： | 1 |
| 7 | Structural evolution of Pd-doped nanoscale zero-valent iron(nZVI)in aqueous media and implications for particle aging and reactivity显示文摘 | Weile yan Andrew A Herzing | | 0，，： | 1 |
| 8 | Nanoscale zero-valent iron (nZVI): Aspects of the core-shell structure and reactions with inorganic species in water显示文摘 | Weile Yan Andrew A. Herzing Christopher J. Kiely Wei-xian Zhang | 2010 | Journal of Contaminant Hydrology2010，，3： | 1 |
| 9 | Li 3 V 2 (PO 4 ) 3 nanocrystals embedded in a nanoporous carbon matrix supported on reduced graphene oxide sheets: Binder-free and high rate cathode material for lithium-ion batteries显示文摘 | Xianhong Rui Daohao Sim Kangming Wong Jixin Zhu Weiling Liu Chen Xu Huiteng Tan Ni Xiao Huey Hoon Hng Tuti Mariana Lim Qingyu Yan | 2012 | Journal of Power Sources2012，，： | 1 |
| 10 | Template-free synthesis of urchin-like Co 3 O 4 hollow spheres with good lithium storage properties显示文摘 | Xianhong Rui Huiteng Tan Daohao Sim Weiling Liu Chen Xu Huey Hoon Hng Rachid Yazami Tuti Mariana Lim Qingyu Yan | 2013 | Journal of Power Sources2013，，： | 1 |
| 11 | Nanoscale zero-valent iron (nZVI) : Aspects of the core-shell structure and reactions with inorganic species in water 显示文摘 | Yan Weile Herzing Andrew A Kiely Christopher J | 2010 | Journal of Contaminant Hydrology2010，118，3： | 1 |
| 12 | Detemtination of the oxide layer thickness in eore-shell zemvalent iron nanopartieles 显示文摘 | Martin John E Her'zing Andrew A Yan Weile | 2008 | Langmuir2008，24，8： | 1 |
| 13 | Superior wide-temperature lithium storage in a porous cobalt vanadate显示文摘Lithium ion batteries(LIBs)that can be operated under extended temperature range hold significant application potentials.Here in this work,we successfully synthesized Co2V2O7 electrode with rich porosity from a facile hydrothermal and combustion process.When applied as anode for LIBs,the electrode displayed excellent stability and rate performance in a wide range of temperatures.Remarkably,a stable capacity of 206 mAhg 1 was retained after cycling at a high current density of 10 A·g-1 for 6,000 cycles at room temperature(25℃).And even when tested under extreme conditions,i.e.,-20 and 60℃,the battery still maintained its remarkable stability and rate capability.For example,at-20℃,a capacity of 633 mAh·g 1 was retained after 50 cycles at 0.1 A·g 1;and even after cycling at 60℃ at 10 A·g-1 for 1,000 cycles,a reversible capacity of 885 mAh·g-1 can be achieved.We believe the development of such electrode material will fciliate progress of the next-generation LIBs with wide operating windows. | Haoliang Chen Dan Yang Xueye Zhuang Dong Chen Weiling Liu Qi Zhang Huey Hoon Hng Xianhong Rui Qingyu Yan Shaoming Huang | 2020 | Nano Research2020，13，7： | 0 |
| 14 | Self-Assembled VS4 Hierarchitectures with Enhanced Capacity and Stability for Sodium Storage显示文摘Sodium-ion batteries(SIBs)have become an auspicious candidate for largescale energy storage by cause of low cost,natural abundance,and similar working principle with lithium-ion batteries(LIBs).At present,there is an urgent need to explore superior anode materials with rapid and stable sodiation/desodiation.Herein,3D self-assembled VS4 curly nanosheets hierarchitectures(VS4-CN-Hs)are developed for SIB anodes,where VS4 possesses a large theoretical sodium storage capacity,and the building block of nanosheets has large exposed surface area to the electrolyte as well as the constructed hierarchitectures can provide abundant buffer space to alleviate the volume expansion.As a result,VS4-CN-Hs anode possesses excellent electrochemical performance under a wide voltage window of 0.01–3.0 V,such as high reversible capacity of 863 mA h g^(−1) at 0.1 A g^(−1),marvelous rate feature(444 mA h g^(−1) at 10 A g^(−1)),and extralong cycle stability(386 mA h g^(−1) after 1000 times at 5 A g^(−1)). | Siling Cheng Kaitong Yao Kunxiong Zheng Qifei Li Dong Chen Yu Jiang Weiling Liu Yuezhan Feng Xianhong Rui Yan Yu | 2022 | Energy & Environmental Materials2022，5，2： | 0 |
| 15 | Pyrenoviologen-based fluorescent sensor for detection of picric acid in aqueous solution显示文摘Two highly emissive pyrenoviologen derivatives were synthesized and used to fabricate fluorescent sensors for detection of picric acid(PA)with good sensitivity and selectivity.The sensitivity of the sensor was attributed to the specific electrostatic association effect of the cationic pyrenoviologens to the picrate anions,which also gave the sensor special selectivity among other compounds with similar structure.The electron transfer between them was attributed to the fluorescence response.Fluorescence lifetime measurements revealed that the quenching is static in nature.The novel and efficient pyrenoviologen derivatives-based sensors offered a strategy to fabricate real-life PA sensor. | Ni Yan Jiale Song Fengyan Wang Longwang Kan Jiahang Song Weiling Wang Wenqiang Ma Weidong Zhang Gang He | 2019 | Chinese Chemical Letters2019，30，11： | 0 |
| 16 | SARS-CoV-2 Nsp8 induces mitophagy by damaging mitochondria显示文摘Autophagy plays an important role in the interaction between viruses and host cells.SARS-CoV-2 infection can disrupt the autophagy process in target cells.However,the precise molecular mechanism is still unknown.In this study,we discovered that the Nsp8 of SARS-CoV-2 could cause an increasing accumulation of autophagosomes by preventing the fusion of autophagosomes and lysosomes.From further investigation,we found that Nsp8 was present on mitochondria and can damage mitochondria to initiate mitophagy.The results of experiments with immunofluorescence revealed that Nsp8 induced incomplete mitophagy.Moreover,both domains of Nsp8 orchestrated their function during Nsp8-induced mitophagy,in which the N-terminal domain colocalized with mitochondria and the C-terminal domain induced auto/mitophagy.This novel finding expands our understanding of the function of Nsp8 in promoting mitochondrial damage and inducing incomplete mitophagy,which helps us to understand the etiology of COVID-19 as well as open up new pathways for creating SARS-CoV-2 treatment methods. | Shan Zong Yan Wu Weiling Li Qiang You Qian Peng Chenghai Wang Pin Wan Tao Bai Yanling Ma Binlian Sun Jialu Qiao | 2023 | Virologica Sinica2023，38，4： | 0 |
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