|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Second harmonic generation in a high-Q lithium niobate microresonator fabricated by femtosecond laser micromachining显示文摘We report on second harmonic generation(SHG) in on-chip high-Q(>105) lithium niobate(Li Nb O3, LN) microresonators fabricated by femtosecond laser micromachining. We examine the efficiency of SHG with either a continuous-wave(CW) or an ultrashort pulsed pump laser. The normalized conversion efficiencies of SHG obtained with the CW and pulsed pump lasers are measured to be 1.35×10?5 m W?1 and 2.30×10?6 m W?1, respectively. | LIN JinTian XU YingXin FANG ZhiWei WANG Min WANG NengWen QIAO LingLing FANG Wei CHENG Ya | 2015 | Science China(Physics,Mechanics & Astronomy)2015，58，11： | 25 |
| 2 | Nickel-exposed Workers in China: A Cohort Study显示文摘There are more than 50 000 workers in Jinchuan Group Co,Ltd(JNMC).Since all staff in JNMC are eligible for a medical examination every two years,only 23 484 nickel-exposed subjects who participated in medical examination were included in this study.Their data,collected from June 22,2011 to September 28,2012,in a | BAI Ya Na YAGN Ai Min PU Hong Quan HE Jie CHENG Ning ZHENG Tong Zhang DAI Min ZHANG Ya Wei BASSING Bryan WANG Qiu Ying | 2014 | Biomedical and Environmental Sciences2014，27，3： | 20 |
| 3 | Identification and Fine Mapping of a Gene Related to Pale Green Leaf Phenotype near the Centromere Region in Rice(Oryza sativa)显示文摘A thermo-insensitive pale green leaf mutant (pgl2) was isolated from T-DNA inserted transgenic lines of rice (Oryza sativa L. subsp. japonica cv. Nipponbare). Genetic analysis indicated that the phenotype was caused by a recessive mutation in a single nuclear-encoded gene. To map the PGL2 gene, an F2 population was constructed by crossing the mutant with Longtefu (Oryza sativa L. subsp. indica). The PGL2 locus was roughly linked to SSR marker RM331 on chromosome 8. To finely map the gene, 14 new InDel markers were developed around the marker, and PGL2 was further mapped to a 2.37 Mb centromeric region. Analysis on chlorophyll contents of leaves showed that there was no obvious difference between the mutant and the wild type in total chlorophyll (Chl) content, while the ratio of Chl a / Chl b in the mutant was only about 1, which was distinctly lower than that in the wild type, suggesting that the PGL2 gene was related to the conversion between Chl a and Chl b. Moreover, the method of primer design around the centromeric region was discussed, which would provide insight into fine mapping of the functional genes in plant centromeres. | ZHU Li LiuWenzhen WU Chao LUAN Wei jiang Fu Ya ping Hu Guo cheng SI Hua min SUN Zong xiu | 2007 | Rice science2007，14，3： | 11 |
| 4 | Reconfigurable directional coupler in lithium niobate crystal fabricated by three-dimensional femtosecond laser focal field engineering显示文摘For crystals, depressed cladding waveguides have advantages such as preservation of the spectroscopic as well as non-linear properties and the capability to guide both horizontal and vertical polarization modes, but fabrication is always quite time consuming. In addition, it is usually difficult to couple modes propagating in different depressed cladding waveguides through evanescent field overlap, so it is often required to dynamically reconfigure photonic waveguide devices using external fields for classical or quantum applications. Here, we experimentally demonstrate the single-scan femtosecond laser transverse writing of depressed cladding waveguides to form a 2 × 2 directional coupler inside lithium niobate crystal, which is integrated with two deeply embedded microelectrodes on both sides of the interaction region to reconfigure the coupling. By focal field engineering of the femtosecond laser, we specially generate a three-dimensional longitudinally oriented ring-shaped focal intensity profile composed of 16 discrete spots to simultaneously write the entire cladding region. The fabricated waveguides exhibit good single guided modes in two orthogonal polarizations at 1550 nm. By applying voltage to the deeply embedded microelectrodes fabricated with the femtosecond laser ablation followed by selective electroless plating, we successfully facilitate the light coupling from the input arm to the cross arm and thus actively tune the splitting ratio. These results open new important perspectives in the efficient fabrication of reconfigurable complex three-dimensional devices in crystals based on depressed cladding waveguides. | Qian Zhang Meng Li Jian Xu Zijie Lin Haofeng Yu Min Wang Zhiwei Fang Ya Cheng Qihuang Gong Yan Li | 2019 | Photonics Research2019，7，5： | 7 |
| 5 | Effects of Outdoor Temperature on Blood Pressure in a Prospective Cohort of Northwest China显示文摘Objective The relationship between outdoor temperature and blood pressure(BP) has been inconclusive. We analyzed data from a prospective cohort study in northwestern China to investigate the effect of outdoor temperature on BP and effect modification by season.Methods A total of 32,710 individuals who participated in both the baseline survey and the first follow-up in 2011–2015 were included in the study. A linear mixed-effect model and generalized additive mixed model(GAMM) were applied to estimate the association between outdoor temperature and BP after adjusting for confounding variables.Results The mean differences in systolic blood pressure(SBP) and diastolic blood pressure(DBP)between summer and winter were 3.5 mm Hg and 2.75 mm Hg, respectively. After adjusting for individual characteristics, meteorological factors and air pollutants, a significant increase in SBP and DBP was observed for lag 06 day and lag 04 day, a 0.28 mm Hg(95% CI: 0.27–0.30) per 1 °C decrease in average temperature for SBP and a 0.16 mm Hg(95% CI: 0.15–0.17) per 1 °C decrease in average temperature for DBP, respectively. The effects of the average temperature on both SBP and DBP were stronger in summer than in other seasons. The effects of the average temperature on BP were also greater if individuals were older, male, overweight or obese, a smoker or drinker, or had cardiovascular diseases(CVDs), hypertension, and diabetes.Conclusions This study demonstrated a significant negative association between outdoor temperature and BP in a high-altitude environment of northwest China. Moreover, BP showed a significant seasonal variation. The association between BP and temperature differed by season and individuals' demographic characteristics(age, gender, BMI), unhealthy behaviors(smoking and alcohol consumption), and chronic disease status(CVDs, hypertension, and diabetes). | ZHENG Shan WANG Min Zhen CHENG Zhi Yuan KANG Feng NIE Yong Hong MI Xiu Ying LI Hai Yan JIN Lan ZHANG Ya Wei BAI Ya Na | 2021 | Biomedical and Environmental Sciences2021，34，2： | 5 |
| 6 | Prevalence of Metabolic Syndrome in Chinese Nickel-exposed Workers显示文摘The prevalence of metabolic syndrome(MS was investigated in Chinese nickel-exposed workers A total of 35 104 subjects were enrolled in this study.The age-adjusted prevalence of MS,BMI≥25diabetes,hypertension,and abnormal lipid was13.9%,29.5%,12.8%,27.5%,and 47.1%respectively.The prevalence of BMI≥25hyperglycemia,and hypertension increased | YANG Ai Min BAI Ya Na PU Hong Quan ZHENG Tong Zhang CHENG Ning LI Juan Sheng LI Hai Yan ZHANG Ya Wei DING Jiao SU Hui REN Xiao Wei HU Xiao Bin | 2014 | Biomedical and Environmental Sciences2014，27，6： | 5 |
| 7 | Sex-specific and Dose-response Relationship between the Incidence of Gallstones and Components of the Metabolic Syndrome in Jinchang Cohort:A Prospective Study显示文摘Gallstones is a very common gastrointestinal disease,involving the formation of masses in the gall bladder or biliary tract,due to abnormally high concentrations of cholesterol or bilirubin in the bile[1].There is a 10%–20%prevalence of gallstones worldwide,and>20%of patients with gallstones show clinical symptoms,implying a substantial disease burden[1]. | YANG Jing Li HUANG Jun Jun CHENG Ning ZHANG De Sheng LIU Si Min HUANG Wen Ya LI Na HUANG Pei Yao DING Jiao LIU Nian BAO Kai Fang DING Jie CHEN Xiao Liang ZHENG Tong Zhang BAI Ya Na | 2020 | Biomedical and Environmental Sciences2020，33，8： | 4 |
| 8 | Electro-optic tuning of a single-frequencyultranarrow linewidth microdisk laser显示文摘Single-frequency ultranarrow linewidth on-chip microlasers with a fast wavelength tunability play a game-changing role in a broad spectrum of applications ranging from coherent communication,light detection and ranging,to metrology and sensing.Design and fabrication of such light sources remain a challenge due to the difficulties in making a laser cavity that has an ultrahigh optical quality(Q)factor and supports only a single lasing frequency simultaneously.Here,we demonstrate a unique single-frequency ultranarrow linewidth lasing mechanism on an erbium ion-doped lithium niobate(LN)microdisk through simultaneous excitation of high-Q polygon modes at both pump and laser wavelengths.As the polygon modes are sparse within the optical gain bandwidth compared with the whispering gallery mode counterpart,while their Q factors(above 10 million)are even higher due to the significantly reduced scattering on their propagation paths,single-frequency lasing with a linewidth as narrow as 322 Hz is observed.The measured linewidth is three orders of magnitude narrower than the previous record in on-chip LN microlasers.Finally,enabled by the strong linear electro-optic effect of LN,real-time electro-optical tuning of the microlaser with a high tuning efficiency of∼50 pm∕100 V is demonstrated. | Jintian Lin Saeed Farajollahi Zhiwei Fang Ni Yao Renhong Gao Jianglin Guan Li Deng Tao Lu Min Wang Haisu Zhang Wei Fang Lingling Qiao Ya Cheng | 2022 | Advanced Photonics2022，4，3： | 4 |
| 9 | A Retrospective Cohort Mortality Study in Jinchang,the Largest Nickel Production Enterprise in China显示文摘Nickel is an essential trace metal used in the occupational setting,resulting in both occupational and nonoccupational exposures to individuals at varying levels.Exposure to nickel has been associated with several toxicities and the International Agency for Research on Cancer has concluded that there is sufficient evidence in humans associating exposure to nickel | MA Li BAI Ya Na PU Hong Quan HE Jie Bryan A.Bassig DAI Min ZHANG Ya Wei ZHENG Tong Zhang CHENG Ning | 2014 | Biomedical and Environmental Sciences2014，27，7： | 4 |
| 10 | A super pan-genomic landscape of rice显示文摘Pan-genomes from large natural populations can capture genetic diversity and reveal genomic complexity.Using de novo longread assembly,we generated a graph-based super pan-genome of rice consisting of a 251-accession panel comprising both cultivated and wild species of Asian and African rice.Our pan-genome reveals extensive structural variations(SVs)and gene presence/absence variations.Additionally,our pan-genome enables the accurate identification of nucleotide-binding leucine-rich repeat genes and characterization of their inter-and intraspecific diversity.Moreover,we uncovered grain weight-associated SVs which specify traits by affecting the expression of their nearby genes.We characterized genetic variants associated with submergence tolerance,seed shattering and plant architecture and found independent selection for a common set of genes that drove adaptation and domestication in Asian and African rice.This super pan-genome facilitates pinpointing of lineage-specific haplotypes for trait-associated genes and provides insights into the evolutionary events that have shaped the genomic architecture of various rice species. | Lianguang Shang Xiaoxia Li Huiying He Qiaoling Yuan Yanni Song Zhaoran Wei Hai Lin Min Hu Fengli Zhao Chao Zhang Yuhua Li Hongsheng Gao Tianyi Wang Xiangpei Liu Hong Zhang Ya Zhang Shuaimin Cao Xiaoman Yu Bintao Zhang Yong Zhang Yiqing Tan Mao Qin Cheng Ai Yingxue Yang Bin Zhang Zhiqiang Hu Hongru Wang Yang Lv Yuexing Wang Jie Ma Quan Wang Hongwei Lu Zhe Wu Shanlin Liu Zongyi Sun Hongliang Zhang Longbiao Guo Zichao Li Yongfeng Zhou Jiayang Li Zuofeng Zhu Guosheng Xiong Jue Ruan Qian Qian | 2022 | Cell Research2022，32，10： | 3 |
| 11 | Microfilament-binding properties of N-terminal extension of the isoform of smooth muscle long myosin light chain kinase显示文摘肌浆球蛋白轻链家族 ases (MLCK ) phosphorylate 在厚细丝的肌浆球蛋白 II 的规章的轻链并且与高亲密关系绑在 F-actin-containing 薄细丝。短肌浆球蛋白光链 kinase (S-MLCK ) 的能力在结构上在它的 N 终点被归因绑 F 肌动朊于 DFRXXL 区域。长肌浆球蛋白光链 kinase (L-MLCK ) 在它的 N 终端延期有二个另外的 DFRXXL 主题和六个象 Ig 一样模块。六个象 Ig 一样模块能够绑定独立地强调纤维。我们从成像分析的结果证明在 L-MLCK 的 N 终端扩展的开始的二个未经触动的象 Ig 一样模块(2Ig ) 最小的有约束力的模块为微细丝被要求有约束力。有约束力的试金证实 F 肌动朊能绑 2Ig。2Ig 肽的 Stoichiometries 为 myofilament 或纯 F 肌动朊是类似的。有约束力的亲密关系比以前报导了的 5DFRXXL 肽稍微低。类似于 DFRXXL 肽, 2Ig 肽也在 vitro 引起了有效 F 肌动朊捆形成。在生活房间, 2Ig 碎片的在表示上与过去绑的 F 肌动朊增加了象伸出形成一样的“尖铁”。我们的结果建议 L-MLCK 可以经由它的 DFRXXL 区域和 2Ig 区域充当有势力 F 肌动朊捆绑蛋白质,暗示 L-MLCK 起在细胞骨架组织的一个作用。 | Chun Xiang Yang Hua Qun Chen Chen Chen Wei Ping Yu Wen Cheng Zhang Ya Jin Peng Wei Qi He Dong Mei Wei Xiang Gao Min Sheng Zhu | 2006 | Cell Research2006，16，4： | 3 |
| 12 | Characterization of Avian Influenza A(H7N9) Virus Prevalence in Humans and Poultry in Huai′an,China:Molecular Epidemiology,Phylogenetic,and Dynamics Analyses显示文摘Objective To trace the source of human H7N9 cases in Huai'an and elucidate the genetic characterization of Huai'an strains associated with both humans and birds in live poultry market.Methods An enhanced surveillance was implemented when the first human H7N9 case was confirmed in Huai'an.Clinical specimens,cloacal swabs,and fecal samples were collected and screened by real-time reverse transcription-polymerase chain reaction(RT-PCR) for H7N9 virus.The positive samples were subjected to further RT-PCR and genome sequencing.The phylodynamic patterns of H7N9 virus within and separated from Huai'an and evolutionary dynamics of the virus were analyzed.Results Six patients with H7N9 infection were previously exposed to live poultry market and presented symptoms such as fever(>38.0 °C) and headaches.Results of this study support the hypothesis that live poultry markets were the source of human H7N9 exposure.Phylogenetic analysis revealed that all novel H7N9 viruses,including Huai'an strains,could be classified into two distinct clades,A and B.Additionally,the diversified H7N9 virus circulated in live poultry markets in Huai'an.Interestingly,the common ancestors of the Huai'an H7N9 virus existed in January 2012.The mean nucleotide substitution rates for each gene segment of the H7N9 virus were(3.09-7.26)×10-3 substitutions/site per year(95% HPD:1.72×10-3 to 1.16×10-2).Conclusion Overall,the source of exposure of human H7N9 cases in Huai'an was live poultry market,and our study highlights the presence of divergent genetic lineage of H7N9 virus in both humans and poultry specimens in Huai'an. | YANG Peng Fei YAN Qing Li LIU Chun Cheng XING Ya Dong ZHANG Min Hui GAO Qiang YU Hao YAO Hai Bo HE Nan Jiang | 2016 | Biomedical and Environmental Sciences2016，29，10： | 3 |
| 13 | Heavy Metal Assessment among Chinese Nonferrous Metal-exposed Workers from the Jinchang Cohort Study显示文摘Environmental exposure to heavy metals has been linked to a wide range of human health hazards.We detected the levels of 15 metals in urine samples from 500 representative sub-samples in an ongoing occupational cohort study(Jinchang Cohort)to directly evaluate metal exposure levels.Fifteen metals,namely As,Ba,Be,Cd,Cs,Cr,Co,Cu,Pb,Mn,Ni,Se,Tl,U,and Zn,were detected by inductively coupled plasma quadruple mass spectrometry.The results showed that median creatinine adjustment and geometric mean urinary metal levels were higher in the heavy metal-exposed group,except Se and Zn,than other reported general or occupational populations.Further studies should address the effects of heavy metals on human health. | YANG Ai Min CHENG Zhi Yuan PU Hong Quan CHENG Ning LI Hai Yan LIU Si Min DING Jiao LI Juan Sheng HU Xiao Bin REN Xiao Wei ZHENG Tong Zhang BAI Ya Na | 2017 | Biomedical and Environmental Sciences2017，30，7： | 2 |
| 14 | Dynamic Changes in DNA Damage and Repair Biomarkers with Employment Length among Nickel Smelting Workers显示文摘Our study explored the dynamic changes in and the relationship between the DNA damage marker8-hydroxy-2’-deoxyguanosine(8-OHd G)and the DNA repair marker 8-hydroxyguanine DNA glycosidase 1(h OGG1)according to the length of occupational employment in nickel smelting workers.One hundred forty | WU Shan BAI Ya Na PU Hong Quan HE Jie ZHENG Tong Zhang LI Hai Yan DAI Min CHENG Ning | 2015 | Biomedical and Environmental Sciences2015，28，9： | 2 |
| 15 | Trend Analysis of Cancer Mortality in the Jinchang Cohort, China,2001-2010显示文摘Objective To describe the baseline data of cancers in the Jinchang Cohort, this paper examined trends in cancer mortality among adults investigated in Jinchang, Gansu province from 2001 to 2010. Methods Mortality data were collected from company departments through administrative documents, death certificates, etc. Trend analyses of cancer mortality were performed on the basis of 925 cancer deaths between 2001 and 2010. Results The crude mortality rate of cancer continuously increased from 161.86 per 100,000 in 2001 to 315.32 per 100,000 in 2010, with an average increase of 7.69% per year in the Jinchang Cohort(16.41% in females compared to 6.04% in males), but the age-standardized mortality rate increased only in females. Thirteen leading cancers accounted for 92.10% of all cancer deaths. The five leading causes of cancer mortality in males were lung, gastric, liver, esophageal, and colorectal cancer, whereas those in females were lung, liver, gastric, breast, and esophageal cancer. Conclusion The overall cancer mortality rate increased from 2001 to 2010 in the Jinchang Cohort, with greater rate of increase in females than in males. Lung, breast, and gastric cancer, in that order, were the leading causes of increased cancer mortality in females. | QU Hong Mei BAI Ya Na CHENG Ning DAI Min ZHENG Tong Zhang WANG Dennis LI Hai Yan HU Xiao Bin LI Juan Sheng REN Xiao Wei SHANG Hui | 2015 | Biomedical and Environmental Sciences2015，28，5： | 2 |
| 16 | Metal Exposure and Risk of Diabetes and Prediabetes among Chinese Occupational Workers显示文摘Objective To study the association between metal exposure and risk of diabetes and prediabetes among Chinese workers exposed to metals.Methods We used data obtained from the baseline survey of the Jinchang Cohort Study of workers in Jinchang Industry,the largest nickel production company in China.A total of 42,122 workers ≥20 years of age were included in the study.A standardized,structured questionnaire was used to collect epidemiological information.Physical examinations and laboratory tests were conducted to evaluate the health status of the participants and to measure various biomarkers including blood sugar,lipids,and urinary metal concentrations.Logistic regression was used to study the association between occupational groups categorized according to the measured metal levels(office workers,low-level;mining/production workers,mid-level;and smelting/refining workers,high-level)and risk of diabetes and prediabetes.Results The overall prevalence of diabetes and prediabetes was 7.5% and 16.8%,respectively.The adjusted odds ratios for diabetes among mining/production workers and smelting/refining workers compared to office workers were 1.5(95% CI:1.3,1.7)and 3.8(95% CI:3.4,4.3),respectively.No association was observed between these occupational groups and prediabetes in this study.Conclusion Occupations associated with higher levels of metal exposure were associated with an increased risk of diabetes in this cohort.More studies are needed to confirm this observed association. | YANG Ai Min CHENG Ning PU Hong Quan LIU Si Min LI Juan Sheng BASSIG Bryan A. DAI Min LI Hai Yan HU Xiao Bin REN Xiao Wei ZHENG Tong Zhang BAI Ya Na | 2015 | Biomedical and Environmental Sciences2015，28，12： | 2 |
| 17 | Highly efficient synthesis and application of aryl diazonium salts via femtosecond laser-tailored 3D flow microfluidic chips显示文摘The first example of the microfluidic chips(MFCs) consisting of centimeter-level 3D channels with highdensity and large-volume fabricated by femtosecond laser micromachining were utilized to develop a time-saving, economical and hazardless flow synthesis process, and its advantages have been proved by in situ formation of aryldiazonium salts and subsequent borylation with bis(pinacolato)diboron. There are several important advantages in our 3D MFC-based flow synthesis technology, including the following:(1) the reaction temperature was altered from ice bath to room temperature;(2) the residence time was reduced by 10 times;(3) the yield was greatly improved, that is, several arylboronates were successfully obtained with higher yield compared to traditional batch process. Therefore, it can be envisioned that a novel, simplified flow synthetic protocol will be developed toward green organic synthesis via MFCs. | Jing Ren Miao Wu Kaiwu Dong Min Zhang Ya Cheng Guoyue Shi | 2023 | Chinese Chemical Letters2023，34，4： | 1 |
| 18 | Nitrous acid (HONO) and its daytime sources at a rural site during the 2004 PRIDE-PRD experiment in China显示文摘 | Hang Su Ya Fang Cheng Min Shao | 2008 | Journal of Geophysical Research2008，，： | 1 |
| 19 | Predicted 10-year Cardiovascular Disease Risk and Its Association with Sleep Duration among Adults in Beijing-Tianjin-Hebei Region,China显示文摘Objective The study aims to predict 10-year cardiovascular disease(CVD)risk and explore its association with sleep duration among Chinese urban adults.Methods We analyzed part of the baseline data of a cohort that recruited adults for health screening by cluster sampling.The simplified Pittsburgh Sleep Quality Index(PSQI)and Framingham 10-year risk score(FRS)were used to measure sleep duration and CVD risk.Demographic characteristics,personal history of chronic diseases,lifestyle factors were collected using a questionnaire.Height,weight,total cholesterol(TC),and high-density lipoprotein cholesterol(HDL-C)were also measured.Multiple logistic regression models were performed to explore the association of sleep duration with the predicted CVD risk.Results We included 31,135 participants(median age 44 years,53.02%males)free of CVD,cerebral stroke,and not taking lipid-lowering agents.Overall,14.05%,and 25.55%of participants were at medium and high predicted CVD risk,respectively.Short sleep was independently associated with increased odds of medium to high risk of predicted 10-year CVD among males(OR=1.10;95%CI:1.01–1.19)and increased odds of medium to high and high risk of predicted 10-year CVD among females(OR=1.23;95%CI:1.08–1.40;OR=1.27;95%CI:1.11–1.44).In contrast,long sleep had no association with cardiovascular risk.Conclusion A substantial number of adults free of CVD were at high 10-year CVD risk.Short sleep was associated with increased odds of predicted CVD risk. | WANG Yu Xue ZHANG Li LI Chun Jun QI Xin FAN Ya Qi HE Jiang Shan GUO Pei HU Jia Lin CHEN Shuo NIU Yu Jie LIU Feng ZHANG Rong LI Qiang MA Shi Tao ZHANG Mian Zhi HONG Cheng Lin ZHANG Min Ying | 2021 | Biomedical and Environmental Sciences2021，34，10： | 1 |
| 20 | Growing Teratoma Syndrome:An Asian Woman With Immature Teratoma of Left Ovary After Chemotherapy显示文摘 | Tsung Ying Hsieh Ya Min Cheng Fong Ming Chang | 2009 | Taiwanese journal of obstetrics and gynecology2009，48，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员