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| 1 | Wet and dry deposition fluxes of heavy metals in Pearl River Delta Region(China):Characteristics,ecological risk assessment,and source apportionment显示文摘The atmospheric deposition of heavy metals poses serious risks to the ecological system and human health. To advance our knowledge of atmospheric dry/wet heavy metal deposition in the PRD region, monthly fluxes were examined based on soluble/insoluble fractions of five heavy metal elements(Cu, Pb, Cd, Cr and Zn) in samples collected from January 2014 to December 2015 at Guangzhou(urban) and Dinghushan(suburban) sites. The ratios of wet/dry deposition fluxes indicated that heavy metal deposition was governed by wet deposition rather than dry deposition in the PRD region. Affected by the shifting of the Asian monsoon, wet deposition fluxes exhibited significant seasonal variation between summer monsoon seasons(April to September) and winter monsoon seasons(October to February) in this region. Cd was classified as an extremely strong potential ecological risk based on solubility and the Hakanson ecological risk index. Source contributions to wet deposition were calculated by PMF, suggesting that dust, biomass burning, industries,vehicles, long-range transport and marine aerosol sources in Guangzhou, and Zn fertilizers,marine aerosol sources, agriculture, incense burning, biomass burning, vehicles and the ceramics industry in Dinghushan, were the potential sources of heavy metals. | Lyumeng Ye Minjuan Huang Buqing Zhong Xuemei Wang Qiulan Tu Haoran Sun Chao Wang Luolin Wu Ming Chang | 2018 | Journal of Environmental Sciences2018，30，8： | 20 |
| 2 | Combustion characteristics and synergy behaviors of biomass and coal blending in oxy-fuel conditions: A single particle co-combustion method显示文摘Co-combustion biomass and coal can effectively reduce the emission of CO_2. O_2/H_2O combustion is regarded as the next generation of oxy-fuel combustion technology. By co-combustion biomass and coal under oxy-fuel condition, the emission of CO_2 can be minimized. This work investigates the co-combustion characteristics of single particles from pine sawdust(PS) and bituminous coal(BC) in O_2/N2, O_2/CO_2 and O_2/H_2O atmospheres at different O_2 mole fractions(21%, 30% and 40%). The experiments were carried out in a drop tube furnace(DTF), and a high speed camera was used to record the combustion process of fuel particles. The combustion temperature was measured by a two-color method. The experiments in O_2/N2 atmosphere indicate that the particles from pine sawdust and bituminous coal all ignite homogeneously. After replacing H_2O for N2, the combustion temperature of volatiles of blended fuel particles decreases, while the combustion temperature of char increases. The ignition delay time in O_2/H_2O atmosphere is shorter than that in O_2/N2 or O_2/CO_2 atmosphere. The combustion temperature of volatiles of blended fuel particles increases as the mass fraction of bituminous coal increases, while the combustion temperature of char of blended fuel particles is higher than that of biomass or bituminous coal. The ignition delay time of blended fuel particles increases with the increasing mass fraction of bituminous coal, and the experimental ignition delay time of blend fuel particles is shorter than the theoretical one. These reveal a synergy during co-combustion process of pine sawdust and bituminous coal. | ZHANG Rui LEI Kai YE BuQing CAO Jin LIU Dong | 2018 | Science China(Technological Sciences)2018，61，11： | 9 |
| 3 | Thermodynamic and economic analyses of a coal and biomass indirect coupling power generation system显示文摘The coal and biomass coupling power genera-tion technology is considered as a promising technology for energy conservation and emission reduction.In this paper,a novel coal and biomass indirect coupling system is proposed based on the technology of biomass gasification and co-combustion of coal and gasification gas.For the sake of comparison,a coal and biomass direct coupling system is also introduced based on the technology of co-combustion of coal and biomass.The process of the direct and the indirect coupling system is simulated.The thermodynamic and economic performances of two systems are analyzed and compared.The simulation indicates that the thermodynamic performance of the indirect coupling system is slightly worse,but the economic performance is better than that of the direct coupling system.When the blending ratio of biomass is 20%,the energy and exergy fficiencies of the indirect coupling system are 42.70%and 41.14%,the intemal rate of returm(IRR)and discounted payback period(DPP)of the system are 25.68%and 8.56 years.The price fluctuation of fuels and products has a great influence on the economic performance of the indirect coupling system.The environmental impact analysis indicates that the indirect coupling system can inhibit the propagation of NOx and reduce the environmental cost. | Buqing YE Rui ZHANG Jin CAO Bingquan SHI Xun ZHOU Dong LIU | 2020 | Frontiers in Energy2020，14，3： | 3 |
| 4 | Circular RNA circZbtb20 maintains ILC3 homeostasis and function via Alkbh5-dependent m6A demethylation of Nr4a1 mRNA显示文摘Group 3 innate lymphoid cells(ILC3s)play critical roles in innate immunity and gut homeostasis.However,how ILC3 homeostasis is regulated remains elusive.Here,we identified a novel circular RNA,circZbtb20,that is highly expressed in ILC3s and required for their maintenance and function.CircZbtb20 deletion causes reduced ILC3 numbers,increasing susceptibility to C.rodentium infection.Mechanistically,circZbtb20 enhances the interaction of Alkbh5 with Nr4a1 mRNA,leading to ablation of the m6A modification of Nr4a1 mRNA to promote its stability.Nr4a1 initiates Notch2 signaling activation,which contributes to the maintenance of ILC3 homeostasis.Deletion of Alkbh5 or Nr4a1 also impairs ILC3 homeostasis and increases susceptibilities to bacterial infection.Thus,our findings reveal an important role of circular RNA in the regulation of innate lymphoid cell homeostasis. | Benyu Liu Nian Liu Xiaoxiao Zhu Liuliu Yang Buqing Ye Huimu Li Pingping Zhu Tiankun Lu Yong Tian Zusen Fan | 2021 | Cellular & Molecular Immunology2021，18，6： | 2 |
| 5 | Transient Activation of Autophagy via Sox2-Mediated Suppression of mTOR Is an Important Early Step in Reprogramming to Pluripotency显示文摘 | Shuo Wang Pengyan Xia Buqing Ye Guanling Huang Jing Liu Zusen Fan | 2013 | Cell Stem Cell2013，，5： | 1 |
| 6 | NKB细胞激活固有淋巴细胞参与抗微生物感染作用显示文摘本研究发现在人和小鼠脾脏和肠系膜淋巴结中存在新天然免疫细胞亚群NKB细胞,NKB细胞具有NK细胞和B细胞的表面分子特征,小鼠中的NKB细胞为NK1.1+NKp46+CD19+IgM+,人中的NKB细胞为NKp46+IgM+CD19+。NKB细胞具有典型的淋巴细胞形态,主要存在于脾脏和肠系膜淋巴结的淋巴滤泡。 | Shuo Wang Pengyan Xia Yi Chen Guanling Huang Zhen Xiong Jing Liu Chong Li Buqing Ye Ying Du 范祖森 | 2017 | 科学新闻2017，19，4： | 0 |
| 7 | Induction of functional neutrophils from mouse fibroblasts by thymidine through enhancement of Tet3 activity显示文摘Neutrophils are derived from bone marrow hematopoietic stem cells(HSCs)and are the largest population among circulating white blood cells in humans,acting as the first line of defense against invading pathogens.Whether neutrophils can be generated by transdifferentiation strategies is unknown.Here,we show that thymidine induces the conversion of mouse fibroblasts to neutrophils.Induced neutrophils(iNeus)showed antibacterial effects and did not undergo malignant transformation in vivo.Importantly,iNeu transplantation cured neutropenia in mice in vivo.Mechanistically,thymidine mediates iNeu conversion by enhancing Tet3 activity.Tet3 initiates the expression of the neutrophil fate decision factors Cebpδ and Rfx1 that drive the transdifferentiation of mouse fibroblasts to neutrophils.Therefore,the induction of functional neutrophils by chemicals may provide a potential therapeutic strategy for patients with neutropenia patients and infectious diseases. | Buqing Ye Liuliu Yang Benyu Liu Nian Liu Dongdong Fan Huimu Li Lei Sun Ying Du Shuo Wang Yong Tian Zusen Fan | 2022 | Cellular & Molecular Immunology2022，19，5： | 0 |
| 8 | 环状RNA抑制了cGAS介导的造血干细胞衰竭显示文摘文章简介固有免疫是机体抵抗外来病原微生物入侵的第一道防线,对病原微生物的及时清除及获得性免疫的建立都有至关重要的作用。固有免疫细胞依靠模式识别受体(PRC)对病原微生物的特征性分子进行识别并诱发机体的固有免疫反应. | 夏朋延 王硕 Buqing Ye Ying Du 李翀 Zhen Xiong Yuan Qu 范祖森 | 2019 | 科学新闻2019，0，2： | 0 |
| 9 | 调节性固有淋巴样细胞调节肠道炎症进程显示文摘文章简介固有淋巴样细胞(ILC)是一类重要的天然淋巴细胞亚群。根据ILC细胞分泌细胞因子的不同可以分为三类,即ILC1、ILC2和ILC3细胞。不同ILC细胞在不同的抵抗病原体反应中均发挥着重要的作用。 | 王硕 夏朋延 陈亿 Yuan Qu Zhen Xiong Buqing Ye Ying Du 田勇 尹芝南 许执恒 范祖森 | 2018 | 科学新闻2018，0，4： | 0 |
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