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| 1 | In vitro observation of the molecular interaction between NodD and its inducer naringenin as monitored by fluorescence resonance energy transfer显示文摘在在根瘤细菌属荚共生的起始的阶段,大多数调整基因被 NodD 蛋白质和植物 inducers 控制。一些基因研究和另外的报告建议了 NodD 可以被它和植物 inducers 的直接相互作用激活。然而,没有如此的一个导致的相互作用的分子的证据。在这份报纸,我们使用了荧光回声精力转移技术看如此的一个相互作用是否在 NodD 和它的使活跃之物之间存在, naringenin,在 vitro。tetracysteine 主题(Cys-Cys-Pro-Gly-Cys-Cys ) 遗传上被插入到 NodD 用 4,5 二度(1,3,2-dithioarsolan-2-yl ) 标记 NodD 荧光黄(闪光) 。Naringenin 被化学连接用荧光黄标记。在在 vitro 的荧光回声精力转移实验,一个领受人的荧光紧张, NodD (90R6 )-FlAsH, 增加了 13% 。这建议 NodD 可以直接在 vitro 与 inducer naringenin 交往并且反应中心在绞链区域 1 NodD 附近是可能的。 | Fengqing Li Bihe Hou Lei Chen Zhujun Yao Guofan Hong | 2008 | Acta Biochimica et Biophysica Sinica2008，40，9： | 2 |
| 2 | Nanocatalysts for hydrogen generation from ammonia borane and hydra- zine borane 显示文摘 | Lu Zhanghui Yao Qilu Zhang Zhujun | 2014 | J Nanomaterials2014，2014，72： | 1 |
| 3 | Sinomenine derivatives with embedment of nitrogen-containing heterocycles exhibiting potent TNF-inhibitory activity显示文摘Inhibitory effect on tumor necrosis factor-(TNF-) production by sinomenine derivatives with embedment of small drug-like nitrogen hetereocyclic moieties has been studied in this work.Several new sinomenine derivatives having chlorophenyl substituent have been found to exhibit much more potent TNF-α inhibitory activity than natural sinomenine and other derivatives. | WANG Meng MA LiYan LOU YangTong BIAN Chao ZHOU TingTing ZHOU HaiBin LIAO HongZe MA Zhao YIN DongSheng CHEN AiZhong WANG ShaoZhong YANG ZhenYu SUN Bing YAO ZhuJun | 2012 | Science China Chemistry2012，55，12： | 1 |
| 4 | One-pot syn- thesis of core-shell Ca@ SiO2 nanospheres and their catal- ysis for hydrolytic dehydrogenation of ammonia borane and hydrazine borane 显示文摘 | Yao Qilu Lu Zhanghui Zhang Zhujun | 2014 | Sci Rep2014，4，： | 1 |
| 5 | Characterization of a trypsin-dependent avian influenza H5N1-pseudotyped HIV vector system for high throughput screening of inhibitory molecules显示文摘 | Zhujun Ao Ami Patel Kaylie Tran Xinying He Keith Fowke Kevin Coombs Darwyn Kobasa Gary Kobinger Xiaojian Yao | 2008 | Antiviral Research2008，，1： | 1 |
| 6 | YL064 activates proteasomal-dependent degradation of c-Myc and synergistically enhances the anti-tumor activity of ABT-199 in diffuse large B cell lymphoma显示文摘Dear Editor,c-Myc is highly associated with poor prognosis and aggressive progression of diffuse large B cell lymphoma(DLBCL)and is thus a desirable drug target.Moreover,studies indicate that 5–15%of DLBCL patients harbor MYC and BCL-2 translocations,while 20–35%DLBCL patients simultaneously overexpress of c-Myc and BCL-2 proteins without gene rearrangements.1 These two types of DLBCL are referred as“double-hit”lymphoma(DHL)and“double-expressor”lymphoma(DEL),respectively.Both DHL and DEL lymphomas have inferior clinical outcomes and are refractory to R-CHOP or even hematopoietic stem cell transplant.2 Thus,targeting both c-Myc and BCL-2 is a promising strategy to treat high-risk DLBCLs.3 Although BCL-2 inhibitors are clinically available,c-Myc remains to be“undruggable”owing to its lack of kinase activity and intrinsically disordered structure.4 Thus,developing clinically applicable c-Myc inhibitor remains challenging. | Huizhuang Shan Yang Cao Xinhua Xiao Meng Liu Yunzhao Wu Qi Zhu Hanzhang Xu Hu Lei Zhujun Yao Yingli Wu | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 1 |
| 7 | N-terminal carboxyl and tetrazole-containing amides as adjuvants to Grb2 SH2 domain ligand binding显示文摘 | Yerrence R Burke Jr Yao Zhujun | 2001 | Bioorganic & Medicinal Chemistry2001，9，： | 1 |
| 8 | Heterostructured NiS_(2)@SnS_(2) hollow spheres as superior high-rate and durable anodes for sodium-ion batteries显示文摘Tin-based sulfides have attracted increasing attention as anodes for sodium-ion batteries(SIBs) owing to their high theoretical capacity;however, the poor rate capability and inferior cycling stability caused by the low electrical conductivity, sluggish kinetics and drastic volume variations during cycling have greatly hampered their practical applications. Herein, heterostructured NiS_(2)@SnS_(2) hybrid spheres were delicately designed and constructed by anchoring interconnected SnS_(2) nanosheets on metalorganic frameworks(MOFs)-derived Ni S_(2) hollow spheres coupled with N-doped carbon skeleton through facile solvothermal and sulfurization/carbonization processes. The unique hollow heterostructure with highly conductive carbon matrix can effectively facilitate the charge transfer kinetics and ensure the desired buffer space while endowing more active sites and enhanced structural integrity, as demonstrated by the experimental and density functional theory(DFT) results. Benefitting from these merits, the NiS_(2)@SnS_(2) hybrid composite displays a high reversible capacity of 820 m Ah g^(-1) after 250 cycles at 1 A g^(-1), and retains a value of 673 m Ah g^(-1)after 1,300 cycles at 5 A g^(-1), manifesting the excellent high-rate and durable sodium storage behaviors when applied in SIBs. This study shall shed more light on the fabricating and interface engineering of other transition metal-based composite anodes for high-performance SIBs. | Chongwei Li Jinchuan Hou Jingyi Zhang Xiaoyue Li Shiqi Jiang Guoqing Zhang Zhujun Yao Tiancun Liu Shenghui Shen Zhiqi Liu Xinhui Xia Jie Xiong Yefeng Yang | 2022 | Science China Chemistry2022，65，7： | 0 |
| 9 | Direct nucleophilic C-1 addition of stable isochromenylium tetrafluoroborates under catalyst-free conditions:A new access to 1H-isochromenes显示文摘Direct additions of the stable isochromenylium tetrafluoroborates (ICTBs) were investigated with a number of readily available nucleophiles 2, yielding a variety of 1H-isochromenes 3 at low or mild temperatures without any catalyst. | HU ZhiLong, QIAN WenJian & YAO ZhuJun State Key Laboratory of Bioorganic and Natural Products Chemistry Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China | 2010 | Science China Chemistry2010，53，4： | 0 |
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