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| 1 | Engineering Herbicide-Resistant Rice Plants through CRISPR/Cas9-Mediated Homologous Recombination of Acetolactate Synthase显示文摘 | Sun, Yongwei Zhang, Xin Wu, Chuanyin He, Yubing Ma, Youzhi Hou, Han Guo, Xiuping Du, Wenming Zhao, Yunde Xia, Lanqin | 2016 | Molecular Plant2016，9，4： | 94 |
| 2 | Diagenesis and porosity evolution of sandstone reservoirs in the East II part of Sulige gas field, Ordos Basin显示文摘It is becoming an important controlling factor of gas exploration and exploitation in the east part of Sulige gas field in the Ordos Basin where the reservoir of main gas formations is tight sandstones. Employing experimental methods of slice identification, casting slice, scan electron microscope, and X-ray diffractions, we studied the characteristics of petrology and diagenesis on reservoirs in Shan1 section of Shanxi formation and He8 section of Shihezi formation of the Permian system in the East II part of Sulige gas field. The results include: (1) the main sandstones in these areas are dominated by lithic sandstone and lithic silicarenite with low grade of maturity; (2) the diagenesis of sandstone in these areas mainly include compaction, cementation, corrosion and alteration. Conclusions are as follows: (1) the diagenetic stage reached period B of the middle diagenetic stage; (2) the early diagenetic compaction is one of the main factors to decreasing porosity; (3) the secondary pores formed by corrosion in acidity medium conditions in period A of the middle diagenetic stage can distinctly ameliorate the poor reservoir capability of sandstone and; (4) cementation in period B of the middle diagenetic stage is the most important factor leading to poor physical property of sandstone reservoirs. | Yang Renchao Fan Aiping Han Zuozhen Wang Xiuping | 2012 | International Journal of Mining Science and Technology2012，22，3： | 19 |
| 3 | Depositional and Diagenetic Controls on Sandstone Reservoirs with Low Porosity and Low Permeability in the Eastern Sulige Gas Field, China显示文摘In order to determine the genesis and the factors that control the low-porosity and lowpermeability sandstone reservoirs in the eastern Sulige Gas Field in the Ordos Basin, systematic studies on the sedimentary facies and diagenesis were conducted by means of analysis of cores, thin sections, fluid inclusions, X-ray diffraction, cathode luminescence and scanning electron microscope. It was found that the sand bodies of the major gas reservoirs in the Shan1 section(P1S1) and the He8 section(P2H8) were formed during the Permian as sedimentary facies such as braided-channel bars, braided-river channels and point bars of a meandering river. Four types of diagenetic facies developed subsequently: in order from the best to the poorest properties these are type A(weak compaction, early calcite cement-chlorite film facies), type B(moderate compaction, quartz overgrowth-feldspar corrosion-kaolinite filling facies), type C(strong compaction, late calcite cement-quartz corrosion facies) and type D(matrix filling and strong compaction facies). This diagenesis is undoubtedly the main reason for the poor reservoir properties of sandstone reservoirs, but the sedimentary facies are the underlying factors that greatly affect the diagenesis and thus the reservoir performance. Favorable diagenetic facies developed mainly in relatively small lithofacies such as braided-river channels, channel bars and point bars. The vertical distribution of the physical properties and the diagenetic facies of the reservoirs are related to the stratigraphic succession. Most of the sandstones between mudstones and thin beds of sandstone are unfavorable diagenetic facies. Analyses indicate that siliceous cementation can hardly be stopped by hydrocarbon filling. Authigenic chlorite could hardly protect the primary porosity. It not only occupies pore space, but also blocks pathways through sandstone reservoirs, so that it has significant influence on the permeability. Authigenic chlorite cannot be used as a marker for a specific sedimentary facies because it can be formed in different sedimentary facies, but it indicates high hydrodynamic conditions and presence of favorable reservoirs. | YANG Renchao FAN Aiping A.J.van LOON HAN Zuozhen WANG Xiuping | 2014 | Acta Geologica Sinica(English Edition)2014，88，5： | 16 |
| 4 | Transcriptional activation and phosphorylation of OsCNGC9 confer enhanced chilling tolerance in rice显示文摘Low temperature is a major environmental factor that limits plant growth and productivity.Although transient elevation of cytoplasmic calcium has long been recognized as a critical signal for plant cold tolerance,the calcium channels responsible for this process have remained largely elusive.Here we report that OsCNGC9,a cyclic nucleotide-gated channel,positively regulates chilling tolerance by mediating cytoplasmic calcium elevation in rice(Oryza sativa).We showed that the loss-of-function mutant of OsCNGC9 is defective in cold-induced calcium influx and more sensitive to prolonged cold treatment,whereas OsCNGC9 overexpression confers enhanced cold tolerance.Mechanistically,we demonstrated that in response to chilling stress,OsSAPK8,a homolog of Arabidopsis thaliana OST1,phosphorylates and activates OsCNGC9 to trigger Ca2+influx.Moreover,we found that the transcription of OsCNGC9 is activated by a rice dehydration-responsive element-binding transcription factor,OsDREB1A.Taken together,our results suggest that OsCNGC9 enhances chilling tolerance in rice through regulating cold-induced calcium influx and cytoplasmic calcium elevation. | Jiachang Wang Yulong Ren Xi Liu Sheng Luo Xiao Zhang Xin Liu Qibing Lin Shanshan Zhu Hua Wan Yang Yang Yu Zhang Bin Lei Chunlei Zhou Tian Pan Yongfei Wang Mingming Wu Ruonan jing Yang Xu Meng Han Fuqing Wu Cailin Lei Xiuping Guo Zhijun Cheng Xiaoming Zheng Yihua Wang Zhigang Zhao Ling Jiang Xin Zhang Yong-Fei Wang Haiyang Wang Jianmin Wan | 2021 | Molecular Plant2021，14，2： | 10 |
| 5 | The wheat MYB-related transcription factor TaMYB72 promotes flowering in rice显示文摘Through large-scale transformation analyses, Ta MYB72 was identified as a flowering time regulator in wheat. Ta MYB72 is a MYB family transcription factor localized to the nucleus. Three Ta MYB72 homologs,Ta MYB72-A, Ta MYB72-B and Ta MYB72-D, cloned from hexaploid wheat were mapped to the short arm of the group 6 chromosomes. Under the long-day conditions,over-expression of the Ta MYB72 in rice shortened the flowering time by approximately 12 d. Expression analyses suggest that Ta MYB72 may function through upregulation of florigen genes Hd3 a and RFT1. | Lichao Zhang Guoxiang Liu Jizeng Jia Guangyao Zhao Chuan Xia Lina Zhang Fu Li Qiang Zhang Chunhao Dong Shuangcheng Gao Longzhi Han Xiuping Guo Xin Zhang Jinxia Wu Xu Liu Xiuying Kong | 2016 | Journal of Integrative Plant Biology2016，58，8： | 8 |
| 6 | The changes on synchronizing ability of coupled networks from ring networks to chain networks显示文摘In this paper, two different ring networks with unidirectional couplings and with bidirectional couplings were discussed by theoretical analysis. It was found that the effects on synchronizing ability of the two different structures by cutting a link are completely opposite. The synchronizing ability will decrease if the change is from bidirectional ring to bidirectional chain. Moreover, the change on synchro- nizing ability will be four times if the number of N is large enough. However, it will increase obviously from unidirectional ring to unidirectional chain. It will be N 2/(2π2) times if the number of N is large enough. The numerical simulations confirm the conclusion in quality. This paper also discusses the effects on synchronization by adding one link with different length d to these two different structures. It can be seen that the effects are different. Theoretical results are accordant to numerical simulations. Synchronization is an essential physics problem. These results pro- posed in this paper have some important reference meanings on the real world networks, such as the bioecological system networks, the designing of the circuit, etc. | HAN XiuPing LU dunAn | 2007 | Science in China(Series F)2007，50，4： | 5 |
| 7 | SARS-CoV-2 crosses the blood-brain barrier accompanied with basement membrane disruption without tight junctions alteration显示文摘SARS-CoV-2 has been reported to show a capacity for invading the brains of humans and model animals.However,it remains undear whether and how SARS-CoV-2 crosses the blood-brain barrier(BBB).Herein,SARS-CoV-2 RNA was occasionally detected in the vascular wall and perivascular space,as well as in brain microvascular endothelial cells(BMECs)in the infected K18-hACE2 transgenic mice.Moreover,the permeability of the infected vessel was in creased.Furthermore,disin tegrity of BBB was discovered in the infected hamsters by administration of Evans blue.Interestingly,the expression of claudin5,ZO-1,occludin and the ultrastructure of tight junctions(TJs)showed unchanged,whereas,the basement membrane was disrupted in the infected animals.Using an in vitro BBB model that comprises primary BMECs with astrocytes,SARS-CoV-2 was found to infect and cross through the BMECs.Consistent with in vivo experiments,the expression of MMP9 was increased and collagen IV was decreased while the markers for TJs were not altered in the SARS-CoV-2-infected BMECs.Besides,inflammatory responses including vasculitis,glial activation,and upregulated inflammatory factors occurred after SARS-CoV-2 infection.Overall,our results provide evidence supporting that SARS-CoV-2 can cross the BBB in a transcellular pathway accompanied with basement membrane disrupted without obvious alteration of TJs. | Ling Zhang Li Zhou Linlin Bao Jiangning Liu Hua Zhu Qi Lv Ruixue Liu Wei Chen Wei Tong Qiang Wei Yanfeng Xu Wei Deng-Hong Gao Jing Xue Zhiqi Song Pin Yu Yunlin Han Yu Zhang Xiuping Sun Xuan Yu Chuan Qin | 2021 | Signal Transduction and Targeted Therapy2021，6，10： | 2 |
| 8 | Adaptive Feedback Syn- chronization of Lu System显示文摘 | Han Xiuping Lu Junan Wu Xiaoqun | 2004 | Chaos Solitons & Fractals2004，24，1： | 1 |
| 9 | Preparation and evaluation of a molecularly imprinted sol gei material for on-line solid-phase extraction coupled with high performance liquid chromatography for the determination of trace penla - chlorophenol in water samples显示文摘 | Han Deman Fang Guozheng Yan Xiuping | 2005 | journal of Chromatography A2005，1100，2： | 1 |
| 10 | A-daptive feedback synchronization of a unified chaotic sys-tem显示文摘 | LU Junan WU Xiaoqun HAN Xiuping | 2004 | Physics Letters A2004，329，45： | 1 |
| 11 | Preparation and evaluation of a molecularly imprinted sol-gel material for on-line solid-phase extraction coupled with high performance liquid chromatography for the determination of trace pentachlorophenol in water sarnples显示文摘 | HAN Deman FANG Guozhen YAN Xiuping | 2005 | J Chromatogr: A2005，1100，2： | 1 |
| 12 | Synchronization of impulsively coupled system显示文摘 | Xiuping Han Jun-An Lu Xiaoqun Wu | 2008 | Interna- tional Journal of Bifurcation and Chaos2008，18，5： | 1 |
| 13 | Preparation and evaluation of a molecularly imprinted sol-gel material for on-line solid-phase extraction coupled with high performance liquid chromatography for the determination of trace penta- chlorophenol in water samples 显示文摘 | HAN Deman FANG Guozhen YAN Xiuping | 2005 | J Chromatogr A2005，1100，2： | 1 |
| 14 | Adaptive Coupled Synchronization Among Multi-Lorenz Systems Family 显示文摘 | LU Jun'an HAN Xiuping LI Yitian | 2007 | Chaos Solitons and Fractals2007，31，4： | 1 |
| 15 | PBL teaching model used in neurology care in clinical practice 显示文摘 | Rui YanHung Han Shufang Fan Xiuping | 2012 | Contemporary Nurse2012，11，11： | 1 |
| 16 | Supporting Seeder and Planting Technology for Spring Corn in Arid Areas显示文摘The annual rainfall is low and the fresh water resources are scarce for the rainfed farming in dry zone of northern China,which seriously affects the sowing and growth of spring corn. In order to solve this problem,the technology of ridge-mulching and side-sowing of spring corn is put forward,the supporting compound operation seeder is developed,and the effect of different speed on the quality of sowing is tested and analyzed. Under the test conditions described in this paper,the seeding operation with a high speed( up to 6 km/h) can be realized,and the quality of the seeding operation can meet the requirements of the national standards. The application of this machine can solve the problem of ' drought damage at the booting stage' for spring corn,thereby realizing the deep fusion of farming machine and agronomy in dry farming of northern China,and achieving the integration of farming machine and agronomy. | Xiuping ZHANG Lin CHEN Guochang FAN Xudong YAN Xingmao YUAN Yazhen ZHANG Yu XIAO Zile HAN | 2018 | Asian Agricultural Research2018，10，4： | 0 |
| 17 | Characterization on the Microstructures of Brominated Natural Rubber from Latex显示文摘To elucidate the mechanism of brominated natural rubber(BNR), eight BNR samples with different bromine content were prepared from latex in different bromination time, and the microstructures were characterized by Fourier transform infrared spectroscopy(FTIR) and ~1H-NMR spectroscopy, respectively. The hardness of BNR increased and its nature transformed from elastomer to resin with the increase of bromine content. Unlike chlorinated natural rubber(CNR), FTIR showed that there were no carbonyl groups on the molecular chains of BNR. ~1H-NMR spectroscopy revealed that the reaction activity of bromine and the secondary hydrogen atom of BNR were much higher than those of the primary one. The brominated substitution took place in the hydrogen atom of CH_3 and CH_2 groups firstly, then in the late period of bromination the bond of C=C was transferred to the saturated bond of C-C due to the Markovnikov addition of hydrogen bromide. Based on these findings, the mechanism of BNR from latex could be deduced as a free radical reaction and the detailed bromination process was presented. | 薛行华 LIU Yafei HAN Xiuping LI Guang WANG Zhiyong | 2019 | Journal of Wuhan University of Technology(Materials Science)2019，34，1： | 0 |
| 18 | A facile phototheranostic nanoplatform integrating NIR-Ⅱ fluorescence/PA bimodal imaging and image-guided surgery/PTT combinational therapy for improved antitumor efcacy显示文摘Phototheranostic with highly integrated functions is an attractive platform for cancer management. It remains challenging to develop a facile phototheranostic platform with complementary bimodal imaging and combinational therapy capacity. Herein, the small-molecule cyanine IR780 loaded liposomes have been harnessed as a nanoplatform to simultaneously realize photoacoustic(PA)/the second near-infrared window(NIR-Ⅱ) fluorescence imaging and image-guided surgery/adjuvant photothermal therapy(PTT).This nanoplatform exhibits attractive properties like uniform controllable size, stable dispersibility, NIR-Ⅱ fluorescence emission, photothermal conversion, and biocompatibility. Benefiting from the complementary PA/NIR-Ⅱ fluorescence bimodal imaging, this nanoplatform was successfully applied in precise vasculature delineation and tumor diagnosis. Interestingly, the tumor was clearly detected by NIR-Ⅱ fluorescence imaging with the highest tumor-to-normal-tissue ratio up to 12.69, while signal interference from the liver was significantly reduced, due to the difference in the elimination rate of the nanoplatform in the liver and tumor. Under the precise guidance of the image, the tumor was accurately resected, and the simulated residual lesion after surgery was completely ablated by adjuvant PTT. This combined therapy showed improved antitumor efcacy over the individual surgery or PTT. This work develops a facile phototheranostic nanoplatform with great significance in accurately diagnosing and effectively treating tumors using simple NIR light irradiation. | Xiuping Han Wenyou Fang Tianqi Zhang Xuan Zhong Kun Qian Zhitao Jiang Rongfeng Hu Guoqiang Shao Lei Zhang Qing Zhang | 2022 | Journal of Materials Science & Technology2022，，35： | 0 |
| 19 | Analysis and Design of Time-Delay Impulsive Systems Subject to Actuator Saturation显示文摘This paper investigates the exponential stability and performance analysis of nonlinear time-delay impulsive systems subject to actuator saturation. When continuous dynamics is unstable, under some conditions, it is shown that the system can be stabilized by a class of saturated delayed-impulses regardless of the length of input delays. Conversely, when the system is originally stable, it is shown that under some conditions, the system is robust with respect to sufficient small delayed-impulses. Moreover, the design problem of the controller with the goal of obtaining a maximized estimate of the domain of attraction is formulated via a convex optimization problem. Three examples are provided to demonstrate the validity of the main results. | Chenhong Zhu Xiuping Han Xiaodi Li | 2024 | IEEE/CAA Journal of Automatica Sinica2024，11，1： | 0 |
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