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| 1 | Stretching characteristics and its dynamic significance of the northern continental margin of South China Sea显示文摘To investigate the thinning of the whole crust, and the contribution of the upper versus lower crust to the stretching since Cenozoic, we calculated the stretching factor of the northern margin of South China Sea with data such as whole crustal thickness, depth of Cenozoic sedimentary basement and the horizontal displacement of faults. An isometric line drawing on whole crustal stretching factor is then obtained. Along the seismic Line 1530 in Baiyun sag, we also calculated the stretching factors of the upper and lower crust. The results suggest that the whole crustal thickness decreases seaward while the whole crustal stretching factor increases from shelf to slope. The Moho upwells highest beneath where the crust is thinned most. The value of the whole crustal stretching factor ranges from 1.5 to 6. Two areas were thinned intensely: the center of Yinggehai Basin, and the Baiyun sag in the Pearl River Mouth Basin. The calculation of the upper and lower crustal stretching factors from DSP1530 in Baiyun sag shows that the original crust of Baiyun sag should be thinned before deformation. Its pre-Cenozoic evolution as well as tectonic position during Cenozoic might be responsible for that. | ZHANG YunFan SUN Zhen ZHOU Di GUO XingWei SHI XiaoBin WU XiangJie PANG Xiong | 2008 | Science China Earth Sciences2008,51,3: | 15 |
| 2 | Aberrant DNA methylation in 5′ regions of DNA methyltransferase genes in aborted bovine clones显示文摘High rate of abortion and developmental abnormalities is thought to be closely associated with inefficient epigenetic reprogramming of the transplanted nuclei during bovine cloning. It is known that one of the important mechanisms for epigenetic reprogramming is DNA methylation. DNA methylation is established and maintained by DNA methyltransferases (DNMTs), therefore, it is postulated that the inefficient epigenetic reprogramming of transplanted nuclei may be due to abnormal expression of DNMTs. Since DNA methylation can strongly inhibit gene expression, aberrant DNA methylation of DNMT genes may disturb gene expression. But presently, it is not clear whether the methylation abnormality of DNMT genes is related to developmental failure of somatic cell nuclear transfer embryos. In our study, we analyzed methylation patterns of the 5′ regions of four DNMT genes including Dnmt3a, Dnmt3b, Dnmt1 and Dnmt2 in four aborted bovine clones. Using bisulfite sequencing method, we found that 3 out of 4 aborted bovine clones (AF1, AF2 and AF3) showed either hypermethylation or hypomethylation in the 5′ regions of Dnmt3a and Dnmt3b, indicating that Dnmt3a and Dnmt3b genes are not properly reprogrammed. However, the individual AF4 exhibited similar methylation level and pattern to age-matched in vitro fertilized (IVF) fetuses. Besides, we found that the 5′ regions of Dnmt1 and Dnmt2 were nearly completely unmethylated in all normal adults, IVF fetuses, sperm and aborted clones. Together, our results suggest that the aberrant methylation of Dnmt3a and Dnmt3b 5′ regions is probably associated with the high abortion of bovine clones. | Jinghe Liu Xingwei Liang Jiaqiao Zhu Liang Wei Yi Hou Da-Yuan Chen Qing-Yuan Sun | 2008 | Journal of Genetics and Genomics2008,35,9: | 10 |
| 3 | Safety study of Folfox-HAIC in relieving bed restriction显示文摘Objective:To investigate the safety of relieving bed restriction in hepatic arterial infusion chemotherapy(HAIC)and its effects on patient comfort.Methods:A prospective study was conducted.Patients with malignant liver tumors,who met the enrollment criteria,were randomly divided into experimental and control groups.During HAIC treatment,the patients in the experimental group,who were not confined to bed and could get out of bed,used electronic injection pumps to infuse chemotherapy drugs.The patients in the control group,who were strictly confined to bed and prohibited from getting out of bed,used infusion pumps to infuse chemotherapy drugs.The complications of the two groups were observed.The Christenson standard improved method was used to evaluate the bleeding and hematoma of limbs on the operation side.The Kolcaba General Comfort Questionnaire(GCQ)and Barthel Index(BI)were used to evaluate the two groups.Results:Ninety patients with malignant liver tumors were enrolled,including 53 with primary liver cancer and 37 with colorectal liver metastasis.There were 70 males and 20 females,aged 41-81 years old,with an average age of 61.6±9.248 years old.There were 60 patients in the experimental group and 30 patients in the control group.All patients underwent HAIC.The study showed that,during the treatment period,there were 3 cases of postoperative puncture point hematoma formation in the two groups,including 2 cases in the experimental group(2/60,3.3%)and 1 case in the control group(1/30,3.3%).The difference was not statistically significant(p>0.05).There were 5 cases of postoperative puncture point bleeding,including 4 cases in the experimental group(4/60,6.7%)and 1 case in the control group(1/30,3.3%),and the difference was not statistically significant(p>0.05).A total of 23 cases,with 6 cases in the experimental group(6/60,10%)and 17 cases in the control group(17/30,56.7%),complained of back pain after the operation,and the difference was statistically significant(p<0.05).Twenty-one cases complained of poor defecation after the operation,including 10 cases in the experimental group(10/60,16.7%)and 11 cases in the control group(11/30,36.7%).The difference was statistically significant(p<0.05).During the period of infusion chemotherapy,the two groups of patients had there was a significant difference between the two groups in terms of comfort status(GCQ)(88.78±6.705,78.47±9.519,p<0.001)and self-care ability(BI)(74.25±9.152,66.83±6.628,p<0.001).Conclusion:During HAIC treatment,getting out of bed is safe and reliable and can increase the patients’comfort and self-care ability.Hence,it merits clinical application. | Xiaoyun Zhao Xingwei Sun Jian Jing Huimin Zhou Yong Jin | 2021 | Journal of Interventional Medicine2021,4,4: | 6 |
| 4 | Draft genome sequence of cauliflower(Brassica oleracea L.var.botrytis)provides new insights into the C genome in Brassica species显示文摘Cauliflower is an important variety of Brassica oleracea and is planted worldwide.Here,the high-quality genome sequence of cauliflower was reported.The assembled cauliflower genome was 584.60 Mb in size,with a contig N50 of 2.11 Mb,and contained 47,772 genes;56.65%of the genome was composed of repetitive sequences.Among these sequences,long terminal repeats(LTRs)were the most abundant(32.71%of the genome),followed by transposable elements(TEs)(12.62%).Comparative genomic analysis confirmed that after an ancient paleohexaploidy(γ)event,cauliflower underwent two whole-genome duplication(WGD)events shared with Arabidopsis and an additional whole-genome triplication(WGT)event shared with other Brassica species.The present cultivated cauliflower diverged from the ancestral B.oleracea species~3.0 million years ago(Mya).The speciation of cauliflower(~2.0 Mya)was later than that of B.oleracea L.var.capitata(approximately 2.6 Mya)and other Brassica species(over 2.0 Mya).Chromosome no.03 of cauliflower shared the most syntenic blocks with the A,B,and C genomes of Brassica species and its eight other chromosomes,implying that chromosome no.03 might be the most ancient one in the cauliflower genome,which was consistent with the chromosome being inherited from the common ancestor of Brassica species.In addition,2,718 specific genes,228 expanded genes,2 contracted genes,and 1,065 positively selected genes in cauliflower were identified and functionally annotated.These findings provide new insights into the genomic diversity of Brassica species and serve as a valuable reference for molecular breeding of cauliflower. | Deling Sun Chunguo Wang Xiaoli Zhang Wenlin Zhang Hanmin Jiang Xingwei Yao Lili Liu Zhenghua Wen Guobao Niu Xiaozheng Shan | 2019 | Horticulture Research2019,6,1: | 6 |
| 5 | Magnetostrictive and Kinematic Model Considering the Dynamic Hysteresis and Energy Loss for GMA显示文摘Due to the influence of magnetic hysteresis and energy loss inherent in giant magnetostrictive materials(GMM), output displacement accuracy of giant magnetostrictive actuator(GMA) can not meet the precision and ultra precision machining. Using a GMM rod as the core driving element, a GMA which may be used in the field of precision and ultra precision drive engineering is designed through modular design method. Based on the Armstrong theory and elastic Gibbs free energy theory, a nonlinear magnetostriction model which considers magnetic hysteresis and energy loss characteristics is established.Moreover, the mechanical system differential equation model for GMA is established by utilizing D'Alembert's principle. Experimental results show that the model can preferably predict magnetization property, magnetic potential orientation, energy loss for GMM. It is also able to describe magnetostrictive elongation and output displacement of GMA. Research results will provide a theoretical basis for solving the dynamic magnetic hysteresis,energy loss and working precision for GMA fundamentally. | Huifang LIU Xingwei SUN Yifei GAO Hanyu WANG Zijin GAO | 2017 | Chinese Journal of Mechanical Engineering2017,30,2: | 3 |
| 6 | Programmed cell death 4 (PDCD4) mediates the sensitivity of gastric cancer cells to TRAIL-induced apoptosis by down-regulation of FLIP expression显示文摘 | Weiqiang Wang Jingjing Zhao Hongbin Wang Yonggang Sun Zhihong Peng Gang Zhou Lilin Fan Xingwei Wang Shiming Yang Rongquan Wang Dianchun Fang | 2010 | Experimental Cell Research2010,,15: | 2 |
| 7 | Sampling theorem for multiwavelet subspaces显示文摘Sampling theorem on multiwavelet subspaces is established. Necessary and sufficient conditions are obtained. The result covers the Shannon’s sampling theorem and the early results on the sampling theorem for wavelet subspaces. | Wenchang Sun Xingwei Zhou | 1999 | Chinese Science Bulletin1999,44,14: | 2 |
| 8 | Irregular Gabor frames and their stability显示文摘 | Wenchang Sun Xingwei Zhou | 2002 | proc2002,,9: | 1 |
| 9 | On the sampling theorem for wavelet subspaees 显示文摘 | ZHOU Xingwei SUN Wenchang | 1999 | J Fourier Anal Appl1999,5,4: | 1 |
| 10 | Irregular wavelet frames显示文摘 | Wenchang Sun Xingwei Zhou | 2000 | Science in China Series A: Mathematics2000,,2: | 1 |
| 11 | Machi- ning Theory of Forming Complex Inner Helicoid and Nu- merical Algorithm to Design Contour of the Disc-mill Cuter显示文摘 | WANG Ke WANG Shuqiang SUN Xingwei | 2012 | Applied Mechanics and Materials2012,141,: | 1 |
| 12 | A reverse auction based allocation mechanism in the cloud computing environment 显示文摘 | Wang Xingwei Sun Jiajia Li Hongxing | 2013 | Applied Mathematics & Information Sciences2013,7,1: | 1 |
| 13 | Average sampling in spline subspace 显示文摘 | Sun Wenchang Zhou Xingwei | 2000 | Applied Mathematics Letters2000,15,: | 1 |
| 14 | Frames and sampling theorem显示文摘 | Wenchang Sun Xingwei Zhou | 1998 | Science in China Series A: Mathematics1998,,6: | 1 |
| 15 | Application of a'trous Wavelet to Satellite Telemetry Data Reeursive Predic- tion 显示文摘 | Sun zhenming Jiang xingwei Wang xiaofeng | 2004 | Journal of Nanjing Universi-ty of Science and Techonl- ogy2004,28,6: | 1 |
| 16 | Efficient estimation for additive hazards regression with bivariate current status data显示文摘This paper discusses efficient estimation for the additive hazards regression model when only bi- variate current status data are available.Current status data occur in many fields including demographical studies and tumorigenicity experiments (Keiding,1991;Sun,2006) and several approaches have been proposed for the additive hazards model with univariate current status data (Lin et al.,1998;Martinussen and Scheike,2002).For bivariate data,in addition to facing the same problems as those with univariate data,one needs to deal with the association or correlation between two related failure time variables of interest.For this,we employ the copula model and an efficient estimation procedure is developed for inference.Simulation studies are performed to evaluate the proposed estimates and suggest that the approach works well in practical situations.An illustrative example is provided. | TONG XingWei 1,,HU Tao 2 & SUN JianGuo 3,4 1 School of Mathematical Sciences,Beijing Normal University,Beijing 100875,China 2 School of Mathematical Sciences,Capital Normal University,Beijing 100048,China 3 School of Mathematics,Jilin University,Changchun 130012,China 4 Department of Statistics,University of Missouri,Columbia,MO 65211,USA | 2012 | Science China Mathematics2012,55,4: | 1 |
| 17 | On the sampling theorem for wavelet subspaces显示文摘 | Xingwei Zhou Wenchang Sun | 1999 | The Journal of Fourier Analysis and Applications1999,,4: | 1 |
| 18 | Frames and sampling theorem显示文摘 | Wenchang Sun Xingwei Zhou | 1998 | Science in China Series A: Mathematics1998,,6: | 1 |
| 19 | Irregular wavelet frames显示文摘 | Wenchang Sun Xingwei Zhou | 2000 | Science in China Series A: Mathematics2000,,2: | 1 |
| 20 | Irregular wavelet frames显示文摘 | Wenchang Sun Xingwei Zhou | 2000 | Science in China Series A: Mathematics2000,,2: | 1 |