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1Novel metabolic and physiological functions of branched chain amino acids: a review显示文摘It is widely known that branched chain amino acids(BCAA) are not only elementary components for building muscle tissue but also participate in increasing protein synthesis in animals and humans. BCAA(isoleucine, leucine and valine) regulate many key signaling pathways, the most classic of which is the activation of the m TOR signaling pathway. This signaling pathway connects many diverse physiological and metabolic roles. Recent years have witnessed many striking developments in determining the novel functions of BCAA including:(1) Insufficient or excessive levels of BCAA in the diet enhances lipolysis.(2) BCAA, especially isoleucine, play a major role in enhancing glucose consumption and utilization by up-regulating intestinal and muscular glucose transporters.(3)Supplementation of leucine in the diet enhances meat quality in finishing pigs.(4) BCAA are beneficial for mammary health, milk quality and embryo growth.(5) BCAA enhance intestinal development, intestinal amino acid transportation and mucin production.(6) BCAA participate in up-regulating innate and adaptive immune responses.In addition, abnormally elevated BCAA levels in the blood(decreased BCAA catabolism) are a good biomarker for the early detection of obesity, diabetes and other metabolic diseases. This review will provide some insights into these novel metabolic and physiological functions of BCAA.Shihai Zhang Xiangfang Zeng Man Ren Xiangbing Mao Shiyan Qiao 2017Journal of Animal Science and Biotechnology2017,8,3:28
2A shallow aftershock sequence in the north-eastern end of the Wenchuan earthquake aftershock zone显示文摘Previous studies show that mature faults are filled with fault gouge in the shallow part and thus cannot accumulate enough strain energy for earthquakes. Therefore most earthquakes are deeper than 5 km, except those events occurring on new faults or in intact rocks. From field observation, Wenchuan earthquake is found to rupture the free surface about 200 km, but the rupture may extend underground much further from teleseismic body waves inversion and aftershocks distribution. In the northeastern end of the rupture zone, deep rupture may induce stress increase near the free surface, and trigger shallow earthquakes. An Ms 5.7 aftershock occurred at Qingchuan, northeast end of Wenchuan earthquake fault on July 24, 2008, featuring thrust mechanism with a 3 km source centroid depth. The shallow focal depth is confirmed with the sPL phase recorded at station L0205. As Rayleigh wave is well only developed for source depth less than 1/5 of epicentral distance, the observed large amplitude of Rg at a distance of 15 km implied depth of 3 km or less. Dozens of aftershocks' sPL waveforms are also analyzed to confirm the source depths less than 3 km. On the other hand, no surface ruptures are found by geological survey or InSAR studies. It is strongly suggested that these aftershock sequences initiate fresh rupture in intact rocks triggered by stress increase from the deep co-seismic rupture of the Wenchuan mainshock.Luo Yan Ni SiDao Zeng XiangFang Zheng Yong Chen QiFu Chen Yong 2010Science China Earth Sciences2010,53,11:26
3Focal mechanisms of the Lushan earthquake sequence and spatial variation of the stress field显示文摘Using broadband seismic records from regional networks, we determined the focal mechanisms and depths of 37 earthquakes in the 2013 M7.0 Lushan earthquake sequence(3.4≤Mw≤5.1) by fitting the three-component waveform data. The results show that the earthquakes are predominantly thrust events, with occasional strike-slip mechanisms. Most earthquakes occurred at depths of 10–20 km. We derived the regional distribution of the average stress field in this area using the damped linear inversion method and the focal mechanisms obtained in this study. The inversion results suggest that the Lushan region and the adjacent area are mostly under compression. The orientations of the maximum principal axes trend NW-SE, with some local differences in the stress distribution at different depths. Compared with the distribution of the stress field in the Wenchuan earthquake area, the stress field in the southwest section of the Longmenshan Fault zone(LFZ) share similar characteristics, predominantly thrust faulting with a few strike-slip events and the maximum compression axes being perpendicular to the LFZ.LUO Yan ZHAO Li ZENG XiangFang GAO Yuan 2015Science China Earth Sciences2015,58,7:24
4Advances in low-protein diets for swine显示文摘Recent years have witnessed the great advantages of reducing dietary crude protein(CP) with free amino acids(AA)supplementation for sustainable swine industry, including saving protein ingredients, reducing nitrogen excretion, feed costs and the risk of gut disorders without impairing growth performance compared to traditional diets. However, a tendency toward increased fatness is a matter of concern when pigs are fed low-protein(LP) diets. In response, the use of the net energy system and balanced AA for formulation of LP diets has been proposed as a solution. Moreover, the extent to which dietary CP can be reduced is complicated. Meanwhile, the requirements for the first five limiting AA(lysine, threonine, sulfur-containing AA, tryptophan, and valine) that growing-finishing pigs fed LP diets were higher than pigs fed traditional diets, because the need for nitrogen for endogenous synthesis of non-essential AA to support protein synthesis may be increased when dietary CP is lowered. Overall, to address these concerns and give a better understanding of this nutritional strategy, this paper reviews recent advances in the study of LP diets for swine and provides some insights into future research directions.Yuming Wang Junyan Zhou Gang Wang Shuang Cai Xiangfang Zeng Shiyan Qiao 2018Journal of Animal Science and Biotechnology2018,9,4:23
5Study and use of the probiotic Lactobacillus reuteri in pigs:a review显示文摘Probiotics are living microorganisms that provide a wide variety of health benefits to the host when ingested in adequate amounts.The bacterial strains most frequently used as probiotic agents are lactic acid bacteria,such as Lactobacillus reuteri,which is one of the few endogenous Lactobacillus species found in the gastrointestinal tract of vertebrates,including humans,rats,pigs and chickens.L reuteri is one of the most well documented probiotic species and has been widely utilized as a probiotic in humans and animals for many years.Initially,L reuteri was used in humans to reduce the incidence and the severity of diarrhea,prevent colic and necrotic enterocolitis,and maintain a functional mucosal barrier.As interest in alternatives to in-feed antibiotics has grown in recent years,some evidence has emerged that probiotics may promote growth,improve the efficiency of feed utilization,prevent diarrhea,and regulate the immune system in pigs.In this review,the characteristics of L reuteri are described,in order to update the evidence on the efficacy of using L.reuteri in pigs.Chengli Hou Xiangfang Zeng Fengjuan Yang Hong Liu Shiyan Qiao 2016Journal of Animal Science and Biotechnology2016,7,1:19
6The M5.0 Suining-Tongnan (China) earthquake of 31 January 2010:A destructive earthquake occurring in sedimentary cover显示文摘Usually, only crystalline basement is strong enough to store the massive strain energy that can be released in a damaging earthquake. By contrast, sedimentary cover is weak, because of its relatively high porosity and fluids. Therefore, it generally cannot accumulate enough energy for strong earthquakes. On January 31, 2010, a M5.0 earthquake occurred near the border of Suining and Tongnan in China. It excited strong short-period Rayleigh waves Rg, indicative of its shallow focal depth. The focal depth is constrained to less than 4 km, most probably in the range of 1-3 km, by modeling amplitude dependence on the frequency and waveforms of teleseismic depth phases (pP, sP). Because the local Mesozoic sedimentary cover is about 6 km thick, this earthquake should have occurred in the sedimentary cover. Though some shallow earthquakes with magnitudes up to M4 occur in Paleozoic sediments, this earthquake is the first M5 event studied in Mesozoic sedimentary cover. This event provides a rare opportunity to study seismogenic processes of damaging earthquakes in sedimentary basins.LUO Yan NI SiDao ZENG XiangFang XIE Jun CHEN Yong LONG Feng 2011Chinese Science Bulletin2011,56,6:17
7Differential expression analysis of the broiler tracheal proteins responsible for the immune response and muscle contraction induced by high concentration of ammonia using iTRAQ-coupled 2D LC-MS/MS显示文摘Ammonia has been considered the contaminant primarily responsible for respiratory disease in poultry. Even though it can cause tracheal lesions, its adverse effects on the trachea have not been sufficiently studied. The present study investigated tracheal changes in Arbor Acres broilers(Gallus gallus) induced by high concentration of ammonia using isobaric tag for relative and absolute quantification(iTRAQ)-based proteome analysis. In total, 3,706 proteins within false discovery rate of 1% were identified, including 119 significantly differentially expressed proteins. Functional analysis revealed that proteins related to immune response and muscle contraction were significantly enriched. With respect to the immune response, up-regulated proteins(like FGA) were pro-inflammatory, while down-regulated proteins participated in antigen processing and antigen presenting(like MYO1G), immunoglobulin and cathelicidin production(like fowlicidin-2), and immunodeficiency(like PTPRC). Regarding muscle contraction, all differentially expressed proteins(like TPM1) were up-regulated. An over-expression of mucin, which is a common feature of airway disease, was also observed. Additionally, the transcriptional alterations of 6 selected proteins were analyzed by quantitative RT-PCR. Overall, proteomic changes suggested the onset of airway obstruction and diminished host defense in trachea after ammonia exposure. These results may serve as a valuable reference for future interventions against ammonia toxicity.Yan Xiong Xiangfang Tang Qingshi Meng Hongfu Zhang 2016Science China(Life Sciences)2016,59,11:15
8Advances in research on solid-state fermented feed and its utilization:The pioneer of private customization for intestinal microorganisms显示文摘With sustainable development of biotechnology,increasing attention has been placed on utilization of solid-state fermented feed(SFF).Solid-state fermented feed has been a candidate strategy to alleviate the contradiction between supply and demand of feed resources,ensure food hygiene safety,promoting energy conservation,and emission reduction.In production of SFF,a variety of organic acids,enzymes,vitamins,peptides,and other unknown growth factors are produced,which could affect performance of animals.Solid-state fermented feed produced by different fermentation techniques has great instability on different physiological stages of different animals,which hinders the application and standardized production of SFF.Herein,we summarize the current advances in the role of the characteristics of SFF prepared by different manufacturing technique and its research progress in animal experiments on growth performance,gastrointestinal ecology,and immune system,so as to provide references for further acquiring a relatively perfect set of SFF production and evaluation systems.Lijie Yang Xiangfang Zeng Shiyan Qiao 2021Animal Nutrition2021,,4:14
9Effect of Heat Input on Microstructure and Mechanical Properties of Joints Made by Bypass-Current MIG Welding–Brazing of Magnesium Alloy to Galvanized Steel显示文摘Experiments were carried out with bypass-current MIG welding–brazing of magnesium alloy to galvanized steel to investigate the effect of heat input on the microstructure and mechanical properties of lap joints. Experimental results indicated that the joint efficiency tended to increase at first and then to reduce with the increase of heat input. The joint efficiency reached its maximum of about 70% when the heat input was 155 J/mm. The metallurgical bonding between magnesium alloy and steel was a thin continuous reaction layer, and the intermetallic compound layer consisted of Mg–Zn and slight Fe–Al phases. It is concluded that bypass-current MIG welding–brazing is a stable welding process, which can be used to achieve defect-free joining of magnesium alloy to steel with good weld appearances.Yugang Miao Bintao Wu Xiangfang Xu Duanfeng Han 2014Acta Metallurgica Sinica(English Letters)2014,27,6:8
10Comparison of ground truth location of earthquake from InSAR and from ambient seismic noise: A case study of the 1998 Zhangbei earthquake显示文摘Because ambient seismic noise provides estimated Green's function (EGF) between two sites with high accuracy, Rayleigh wave propagation along the path connecting the two sites is well resolved. Therefore, earthquakes which are close to one seismic station can be well located with calibration extracting from EGF. We test two algorithms in locating the 1998 Zhangbei earthquake, one algorithm is waveform-based, and the other is traveltime-based. We first compute EGF between station ZHB (a station about 40 km away from the epicenter) and five IC/IRIS stations. With the waveform-based approach, we calculate 1D synthetic single-force Green's functions between ZHB and other four stations, and obtain traveltime corrections by correlating synthetic Green's functions with EGFs in period band of 10-30 s. Then we locate the earthquake by minimizing the differential travel times between observed earthquake waveform and the 1D synthetic earthquake waveforms computed with focal mechanism provided by Global CMT after traveltime correction from EGFs. This waveform-based approach yields a location which error is about 13 km away from the location observed with InSAR. With the traveltime-based approach, we begin with measuring group velocity from EGFs as well as group arrival time on observed earthquake waveforms, and then locate the earthquake by minimizing the difference between observed group arrival time and arrival time measured on EGFs. This traveltime-based approach yields accuracy of 3 km, Therefore it is feasible to achieve GT5 (ground truth location with accuracy 5 km) with ambient seismic noises. The less accuracy of the waveform-based approach was mainly caused by uncertainty of focal mechanism.Jun Xie Xiangfang Zeng Weiwen Chen Zhongwen Zhan 2011Earthquake Science2011,24,2:7
11The simulation of nature gas production from ocean gas hydrate reservoir by depressurization显示文摘The vast amount of hydrocarbon gas encaged in gas hydrates is regarded as a kind of future potential energy supply due to its wide deposition and cleanness. How to exploit gas hydrate with safe, effective and economical methods is being pursued. In this paper, a mathematical model is developed to simulate the hydrate dissocia- tion by depressurization in hydrate-bearing porous medium. The model can be used to analyze the effects of the flow of multiphase fluids, the intrinsic kinetic process of hydrate dissociation, the endothermic process of hydrate dissociation, ice-water phase equilibrium, the variation of permeability, the convection and conduction on the hydrate dissociation and gas and water production. The nu- merical results agreed well with the 1-D and 2-D experiments. The numerical results for 3-D hydrate reservoir show that in the first stage of depressurization gas can be produced effectively from hydrate reservoir. With the depletion of reservoir energy because of endothermic process of hydrate dissociation the gas rate decreases rapidly. Then, methods such as thermal stimulation and inhibitor injection should be considered to replaceBAI YuHu LI QingPing LI XiangFang DU Yan 2008Science China(Technological Sciences)2008,51,8:6
12Imaging shallow structure with active-source surface wave signal recorded by distributed acoustic sensing arrays显示文摘Distributed acoustic sensing(DAS) is one recently developed seismic acquisition technique that is based on fiber-optic sensing. DAS provides dense spatial spacing that is useful to image shallow structure with surface waves.To test the feasibility of DAS in shallow structure imaging,the PoroTomo team conducted a DAS experiment with the vibroseis truck T-Rex in Brady's Hot Springs, Nevada, USA.The Rayleigh waves excited by the vertical mode of the vibroseis truck were analyzed with the Multichannel Analysis of Surface Waves(MASW) method. Phase velocities between5 and 20 Hz were successfully extracted for one segment of cable and were employed to build a shear-wave velocity model for the top 50 meters. The dispersion curves obtained with DAS agree well with the ones extracted from co-located geophones data and from the passive source Noise Correlation Functions(NCF). Comparing to the co-located geophone array, the higher sensor density that DAS arrays provides help reducing aliasing in dispersion analysis, and separating different surface wave modes. This study demonstrates the feasibility and advantage of DAS in imaging shallow structure with surface waves.Zhenghong Song Xiangfang Zeng Clifford H.Thurber Hebert F.Wang Dante Fratta 2018Earthquake Science2018,31,4:4
13Numerical simulation on gas production from a hydrate reservoir underlain by a free gas zone显示文摘Physical and mathematical models of gas production by depressurization from a hydrate reservoir underlain by a free gas zone are established. The mathematical model can interpret the effects of the flow of multiphase fluids, the process of hydrate dissociation, ice-water phase transition, the variation of permeability, the convection and conduction on hydrate dissociation and gas and water production. The evolutions of temperature, pressure, and saturations in the hydrate and free gas zones are eluci-dated during gas production. The variation of some parameters, such as gas and water rates, with time is presented. The results show that the overlying hydrate zone can supply a certain amount of gas to improve the output of a production well and evidently prolong the lifespan of a gas reservoir.BAI YuHu LI QingPing LI XiangFang DU Yan 2009Chinese Science Bulletin2009,54,5:4
14Effects of L-lysine·H2SO4 product on the intestinal morphology and liver pathology using broiler model显示文摘Background: Lysine is used widely in livestock production due to the shortage of feed protein resources.Llysine·H2SO4 contains L-lysine sulphate as well as fermentation co-products which contain other amino acids and phosphorus.However,there are few articles about L-lysine·H2SO4 product regarding intestinal morphology and liver pathology of broiler chickens.In this article,we focus on the absorption and metabolism of L-lysine·H2SO4 revealed in the variation of intestinal morphology and liver pathology to determine the tolerance of chicks for L-lysine·H2SO4.Methods: To evaluate the tolerance of broilers for L-lysine·H2SO4,240 one day old broilers were allocated randomly to one of five dietary treatments which included corn-soybean diets containing 0,1%,4%,7% or 10% L-lysine·H2SO4(L-lysine content = 55%).Results: Supplementation of 1% L-lysine·H2SO4 in the diet had no negative effects.However,4%,7% or 10% Llysine·H2SO4 supplementation produced negative responses on broiler performance,carcass characteristics,blood biochemistry,and particularly on intestinal morphology and liver pathology compared with broilers fed the control diet.Conclusion: Our results show that supplementation with 1% L-lysine·H2SO4 had no negative effects on performance,carcass characteristics,blood biochemistry,intestinal morphology and liver pathology in broilers,but supplementation with 4%,7% or 10% L-lysine·H2SO4 produced a negative response,particularly with respect to intestinal morphology and liver pathology.Hongmin Jia Ting He Haitao Yu Xiangfang Zeng Shihai Zhang Wenfeng Ma Jie Zhang Shiyan Qiao Xi Ma 2019Journal of Animal Science and Biotechnology2019,10,3:3
15Crustal S-wave velocity structure of the Yellowstone region using a seismic ambient noise method显示文摘The Yellowstone volcano is one of the largest active volcanoes in the world,and its potential hazards demand detailed seismological and geodetic studies.Previous studies with travel time tomography and receiver functions have revealed a low-velocity layer in the crust beneath the Yellowstone volcano,suggesting the presence of a magma chamber at depth.We use ambient seismic noise from regional seismic stations to retrieve short-period surface waves and then study the shallow shear velocity structure of the Yellowstone region by surface wave dispersion analysis.We first obtained a crustal model of the area outside of the Yellowstone volcano and then constructed an absolute shear wave velocity structure in combination with receiver function results for the crust beneath the Yellowstone volcano.The velocity model shows a low-velocity layer with shear velocity at around1.3 km/s,suggesting that a large-scale magma chamber exists at shallow levels within the crust of the Yellowstone volcanic region.Yan Lü Sidao Ni Jun Xie Yingjie Xia Xiangfang Zeng Bin Liu 2013Earthquake Science2013,26,5:2
16Leucine Supplementation in a Chronically Protein-Restricted Diet Enhances Muscle Weight and Postprandial Protein Synthesis of Skeletal Muscle by Promoting the mTOR Pathway in Adult Rats显示文摘Bo Zhang Licui Chu Hong Liu Chunyuan Xie Shiyan Qiao Xiangfang Zeng 2017Engineering2017,3,5:2
17Development of new type curves for production analysis in naturally fractured shale gas/tight gas reservoirs显示文摘Xu Bingxiang Haghighi M Li Xiangfang  2013Journal of Petroleum Science and Engineering2013,105,1:1
18A model for gas transport in microfractures of shale and tight gas reservoirs显示文摘Keliu Wu Xiangfang Li Chenchen Wang Zhangxin Chen Wei Yu 2015AIChE J2015,,6:1
19Nano-hybrid shish-kebab: Isotactic polypropylene epitaxial growth on electrospun polyamide 66 nanofibers via isothermal crystallization显示文摘Yanyan Liang Guoqiang Zheng Wenjuan Han Chuntai Liu Jingbo Chen Qian Li Baochen Liu Changyu Shen Xiangfang Peng 2010Materials Letters2010,,4:1
20Effect of oscillatory shear on polystyrene cell morphology显示文摘Gao Changyun Zhou Nanqiao Peng Xiangfang 2006Journal of Cellular Plastics2006,42,3:1
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