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| 1 | Carbon isotope ratios of C_(4) plants in loess areas of North China显示文摘Carbon isotope ratios (δ 13C) of 89 C4 plant samples were determined from the loess area in North China. δ 13C values vary between –10.5‰ and –14.6‰ with a mean of –12.6‰. Along a pre-cipitation gradient from the semi-moist area to the semiarid area, then to the arid area, the δ 13C val-ues of C4 plants show a slight decreasing trend. The δ 13C values of C4 plants in the dry season are found lower than those in the wet season. These trends are opposite to those observed for C3 spe-cies. | WANG Guoan1,2,3, HAN Jiamao 2, ZHOU Liping3, XIONG Xiaogang4, TAN Ming2, WU Zhenhai5 & PENG Jun6 1. Department of Plant Nutrition, China Agricultural University, Beijing 100094, China 2. Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing 100029, China 3. College of Environmental Sciences, MOE Laboratory for Earth Surface Processes, Peking University, Beijing 100871, China 4. Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China 5. Northwest Sci-Tech University of Agriculture and Forestry, Yangling 712100, China 6. Network Center, China Agricultural University, Beijing 100094, China | 2006 | Science China Earth Sciences2006，49，1： | 16 |
| 2 | Quantitative analysis of soil pores under natural vegetation successions on the Loess Plateau显示文摘Soil pore is a key attribute of the soil structure that affects soil reservoir under natural vegetation recovery on the Loess Plateau.This study is to quantitatively analyze soil pore parameters,measured with Computed Tomography(CT) at 15-57 mm depths under five different vegetation succession stages using a concept of substituting 'space' for 'time' in the Ziwuling Forest Region of the Loess Plateau.The results showed that the soil pore parameters,such as pore number,porosity,circularity,and fractal dimension,increased significantly under the natural vegetation successions and varied with the pattern climax community stage>pioneering arbor community stage>scrub community stage>herbaceous community stage>abandoned farmland stage,indicating that natural vegetation recovery could remarkably improve soil pore characteristics.With the vegetation succession,this positive effect will be strengthened gradually,which means that the soil pore parameters may appear to be best at the climax community stage.Soil organic matter content increased linearly with the soil pore parameters(P<0.001).Increased organic matter accumulation was one of the major reasons for the changes in soil pore characteristics in natural vegetation succession. | ZHAO ShiWei1,ZHAO YongGang1,2 & WU JinShui3 1 State Key Laboratory of Soil Erosion and Dryland Farming on the Loess Plateau,Institute of Soil and Water Conservation,Northwest Agriculture & Forestry University,Yangling 712100,China 2 Graduate University of Chinese Academy of Sciences,Beijing 100049,China 3 Institute of Subtropical Agriculture,Chinese Academy of Sciences,Changsha 410125,China | 2010 | Science China Earth Sciences2010，53，4： | 14 |
| 3 | 黄土高原植被建造优化模式显示文摘文章分析了黄土高原植被建设的现状,总结选择了适宜黄土高原植被建设的宏观、中观、微观模式和种植模式,对黄土高原植被建设具有指导意义。 | Wang Youke Wu Qinxiao Han Bin(Northwestern Institute of Soil ans Water Conservation,Academia Sinicaand Ministry of Water Resources,Yangling,Shaaxi,712100) | 1994 | 水土保持研究1994，1，3： | 6 |
| 4 | Immune regulation of hydrogen sulfide in children with acute lymphoblastic leukemia显示文摘 | Du Shuxu Jia Yongrui Tang Hong Sun Yangling Wu Wanshui Sun Liming Du Junbao Geng Bin Tang Chaoshu Jin Hongfang | 2014 | Chinese Medical Journal2014，，21： | 5 |
| 5 | Ameliorating effects of Inonotus obliquus on high fat diet-induced obese rats显示文摘根据从的数据,将在在一年 2030 的世界上有 21.6 亿过重和 11.2 亿个肥胖的个人[1 ] ,它提起多重疾病的风险例如高血压,癌症的糖尿病,心血管的疾病,和几种类型[2,3 ] 。肥胖被看作新陈代谢的混乱,它被高精力吸入主要导致。在哺乳动物,过量精力首先在脂肪质的织物作为 triglyceride (TG ) 被存储。在过去的十年,调整 adipogenesis 的过程的众多的分子很好被记录了。Peroxisome 激活 proliferator 的受体(PPAR-) 为脂肪质的织物的累积被要求并且贡献肥胖[4 ] 。甾醇规章的元素绑定蛋白质(SREBP ) 作为激活胆固醇和丰满的酸合成的全部节目的抄写因素的一个家庭被识别了[5 ] 。Glyceraldehydes 3 磷酸盐 acyltransferase (GPAT ) 和 diacylglycerol acyltransferase (DGAT ) 广泛地在哺乳动物的纸巾被表示并且催化第一并且在 TG 合成的最后的步,分别地[6 ] 。因此,这些分子可以是为肥胖和类脂化合物新陈代谢的评估的大目标。最近,阳光等。[7 ] 证明了在糖尿病的老鼠的类脂化合物的浆液层次显著地与 Inonotus obliquus 的文化肉汤的干燥的事在 3 星期的治疗以后被减少。李和 Hyun [8 ] 证明水摘录从我。obliquus 减少了高脂肪的饮食的胖重量喂的肥胖的老鼠。因此,我们对什么进一步感兴趣,是怎么能我。obliquus 摘录影响类脂化合物新陈代谢并且什么是位于这反肥胖效果下面的可能的机制。在现在的学习,我们造了一个高脂肪的导致食谱的老鼠模型。 | Tao Wu Qingyu Shu Kai Yang Xiaoxian Xie Xia Wang Yangling Wang Anqi Guo Nate Y-uan Binggong Zhao Binbin Chi QiaobeiWu Zhengwei Fu | 2015 | Acta Biochimica et Biophysica Sinica2015，47，9： | 4 |
| 6 | Changes of sulfur dioxide, nuclear factor-κB, and interleukin-8 levels in pediatric acute lymphoblastic leukemia with bacterial inflammation显示文摘 | Wu Wanshui Jia Yongrui Du Shuxu Tang Hong Sun Yangling Sun Liming | 2014 | Chinese Medical Journal2014，，23： | 4 |
| 7 | DYRK1A suppression restrains Mcl-1 expression and sensitizes NSCLC cells to Bd-2 inhibitors显示文摘Objective:Mcl-1 overexpression confers acquired resistance to Bcl-2 inhibitors in non-small cell lung cancer(NSCLC),but no direct Mcl-1 inhibitor is currently available for clinical use.Thus,novel therapeutic strategies are urgently needed to target Mcl-1 and sensitize the anti-NSCLC activity of Bcl-2 inhibitors.Methods:Cell proliferation was measured using sulforhodamine B and colony formation assays,and apoptosis was detected with Annexin V-FITC staining.Gene expression was manipulated using siRNAs and plasmids.Real-time PCR and Western blot were used to measure mRNA and protein levels.Immunoprecipitation and immunofluorescence were used to analyze co-localization o f dual specificity tyrosine-phosphorylation-regulated kinase 1A(DYRK1A)and Mcl-1.Results:Suppression of DYRK1A resulted in reduced Mcl-1 expression in NSCLC cells,whereas overexpression of DYRK1A significantly increased Mcl-1 expression.Suppression of DYRK1A did not alter Mcl-1 mRNA levels,but did result in an accelerated degradation o f Mcl-1 protein in NSCLC cells.Furthermore,DYRK1A mediated proteasome-dependent degradation o f Mcl-1 in NSCLC cells,and DYRK1A co-localized with Mcl-1 in NSCLC cells and was co-expressed with Mcl-1 in tumor samples from lung cancer patients,suggesting that Mcl-1 may be a novel DYRK1A substrate.We showed that combined therapy with harmine and Bcl-2 antagonists significantly inhibited cell proliferation and induced apoptosis in NSCLC cell lines as well as primary NSCLC cells.Conclusions:Mcl-1 is a novel DYRK1A substrate,and the role of DYRK1A in promoting Mcl-1 stability makes it an attractive target for decreasing Bcl-2 inhibitor resistance. | Yangling Li Dongmei Zhou Shuang Xu Mingjun Rao Zuoyan Zhang Linwen Wu Chong Zhang Nengming Lin | 2020 | Cancer Biology & Medicine2020，17，2： | 2 |
| 8 | Large-scale information entropy analysis of important sites in mature and precursor miRNA sequences显示文摘In order to find evidence of consistent sequence conservation or the base correlation degree in miRNA,some important sites in the sequences of reported miRNA and their precursors(pre-miRNA) were investigated via information entropy analysis.Twelve different groups of sites were obtained from special locations(head,tail) in miRNAs of different sources according to taxonomy(animal,plant and virus) and then analyzed by measuring the single base information redundancy(D1(L)) and the adjacent base related information redundancy(D2(L)).The results showed that D2(L) has more information than D1(L),though D1(L) changes roughly consistently with D2(L) in each group.Viral pre-miRNAs are more conservative than those belonging to animals or plants.In addition,U is dominant in most sites compared with other nucleotides.It was also found that in the middle of several groups,there were sites where miRNAs were cut down from pre-miRNAs by Enzyme Dicer which were significantly conservative.This phenomenon shows that the conservatism is an aspect of the of miRNA and may be involved in the recognition and cutting by the Dicer.Those results provided another perspective for understanding more about the primary structure of pre-miRNA. | DU JiangFeng1,2,WU YongJun2,ZHANG YinXia3,WU Lei1,2,WANG XiaoLong3,TAO ShiHeng1,2 1 Bioinformatics Center,Northwest Science and Technology University of Agriculture,Yangling 712100,China 2 College of Life Sciences,Northwest Science and Technology University,Yangling 712100,China 3 College of Science,Northwest Science and Technology University,Yangling 712100,China | 2009 | Science China(Life Sciences)2009，52，8： | 1 |
| 9 | Soil water characteristics in mountain poplar stand and its benefits to soil and water conservation in loess hilly region显示文摘SoilwatercharacteristicsinmountainpoplarstandanditsbenefitstosoilandwaterconservationinloesshillyregionWuQinxiao;LiuXiangdong... | Wu Qinxiao Liu Xiangdong Zhao Hongyan Northwestern Institute of Soil and Water Conservation,Chinese Academy of Sciences and Ministry of Water Conservancy),Yangling 712100,China) | 1994 | Journal of Environmental Sciences1994，6，3： | 1 |
| 10 | Zoology of fractional Chern insulators显示文摘 | Wu Yangle Bernevig B A Regnault N | 2012 | Phys Rev B2012，85，07： | 1 |
| 11 | hsa-miR-96 up-regulates MAP4K1 and IRS1 and may function as a promisingdiagnostic marker in human bladder urothelial carcinomas显示文摘 | Yi Wang Hongmei Luo Yangle Li Tieding Chen Shengpeng Wu Luoyan Yang | 2012 | Molecular Medicine Reports2012，，1： | 1 |
| 12 | hsa-miR-96 up-regulates MAP4K1 and IRS1 and may function as a promisingdiagnostic marker in human bladder urothelial carcinomas显示文摘 | Yi Wang Hongmei Luo Yangle Li Tieding Chen Shengpeng Wu Luoyan Yang | 2012 | Molecular Medicine Reports2012，，1： | 1 |
| 13 | Erratum to DYRK1A suppression restrains Mcl-1 expression and sensitizes NSCLC cells to Bcl-2 inhibitors显示文摘In the published paper1,errors appeared in Figure 1D on page 391.In Figure 1D,an incorrect gel image was shown for Bcl-xL in NCI-H1299 cells.Figure 1D has been updated to correct the mistake above.The errors do not affect the conclusions of this article.We apologize for the errors and for any confusion that they may have caused. | Yangling Li Dongmei Zhou Shuang Xu Mingjun Rao Zuoyan Zhang Linwen Wu Chong Zhang Nengming Lin | 2022 | Cancer Biology & Medicine2022，19，7： | 0 |
| 14 | Mechanism of Macrophage Action in Osteoarthritis显示文摘Osteoarthritis(OA)is the most common chronic joint disease and the main cause of pain and disability in adults(typical clinical OA characteristics),and women are more predisposed to this disease than men.About 400 million people worldwide and more than 100 million in China suffer from arthritis.OA was named the 11th largest contributor of mortality in the world,with a disability rate of as high as 53%,and is among the three major killers threatening the health of the elderly.Colloquially,OA is called the'number one disabling disease of the 21st century.'It is the main reason for the malfunctioned mobility of the elderly.Generally,women and men start to have OA at 40 and 50,respectively.Incidence rates increased dramatically between the ages of 55 and 60.The prevalence rate among older persons over 70 years of age is almost 80-90%.In addition,the disease is a chronic progressive disease,which can not only lead to the decline of life function and the reduction or even loss of quality of life,but also has an important and huge impact on health care and social costs.This disease may also demand higher economic requirements of the affected families.Until now,since the pain mechanism of the disease is not clear,there are no effective treatment methods,and surgical joint replacement is the only choice to treat the end-stage disease.This paper focuses on the role of macrophages in OA development,with particular attention to the occurrence of pain and possible mediators involved. | Yangle Li Jie Zheng Xiaoqing Wu Feng Yang | 2021 | Journal of Clinical and Nursing Research2021，5，4： | 0 |
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