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| 1 | 一种房颤风险评分系统的建立(Framingham心脏研究):基于社区的队列研究显示文摘背景房颤导致了发病率和病死率的显著上升。本研究旨在建立一种预测个体罹患房颤绝对风险的风险评分系统,并提供研究人员评价新危险因素的流程。方法作者评估了Framingham心脏研究中于1968年6月至1987年9月间进行了8044次检测的4764例参与者(55%为女性,年龄45~95岁)。此后,参与者被随访至房颤首发,随访期最长达10年。多变量Coxi回归确认出1(1年内罹患房颤的临床危险因素。次级分析纳入了常规超声心动图检测指标(5152例4参与者,7156次检测)对房颤风险进行再分层评估,并评价超声检测指标能否提高风险预测能力。结果4764例参与者中的457例4(10%)罹患房颤。年龄、性别、体重指数、收缩压、降压治疗、PR间期、有临床意义的心脏杂音及心力衰竭与房颤相关,并被纳入了风险评分模型(除体重指数P=0.08外,其余均为P〈0.05),模型的C统计量为0.78(95%CI0.76~0.80)。10年房颤风险随年龄变化:年龄〈65岁的人群中53例(1%)风险高于15%,而〉65岁的人群中为783例(27%)。为提高预测能力而纳入超声检测指标仅使模型C统计量略微增高,由0.78(95%C10.75~0.80)增至0.79(95%CI0.77~0.82:P=0.005)。超声心动图检测指标并不能改善风险再分层评估(P=0.18)。结论基于社区医疗中易得的临床因素建立的风险评分系统,有助于确认社区个体罹患房颤的风险,评估技术或标志物能否改善风险预测,以及针对高危个体采取预防措施。 | Renate B Schnabel Lisa M Sullivan Daniel Levy Michael J Pencina Joseph M Massaro Ralph B D'Agostino Sr Christopher Newton-Cheh Jennifer F Yamamoto Jared W Magnani Thomas M Tadros William B Kannel Thomas J Wang Patrick T Ellinor Philip A Wolf Ramachanclran S Vasan Emelia J Benjamin 黄刚(译) | 2009 | 世界临床医学2009，，9： | 2 |
| 2 | Computed tomography angiography of the carotid arteries at low k V settings:A prospective randomised trial assessing radiation dose and diagnostic confidence显示文摘 | Beitzke D Wolf F Edelhauser G | 2011 | European Radiology2011，21，11： | 1 |
| 3 | Infertility associated with Eperythrozoon wenyonii infection in a bull 显示文摘 | Montes A J Wolfe D F Welles E G | 1994 | JAVMA1994，204，2： | 1 |
| 4 | Hematologic and semen quality changes in bulls with experimental eperythrozoon infection显示文摘 | WELLES E G TYLER J W WOLFE D F | 1995 | Teriogenology1995，43，： | 1 |
| 5 | Foundations for the study of software architecture显示文摘 | PERRY D E WOLF A F | 1992 | ACM SIGSOFT Software Engineering Notes1992，17，4： | 1 |
| 6 | Achieving sub-pixel geolocation accuracy in support of MODIS land science显示文摘 | Wolfe R E Nishihama M Fleig A J Kuyper J A Roy D P Storey J C and Patt F S | | 0，，1： | 1 |
| 7 | Eperythro-zoon infection in young bulls with scrotal and hindlimb edema,a herd outbreak显示文摘 | WELLES E G TYLER J W WOLFE D F | 1995 | Teriogenology1995，43，： | 1 |
| 8 | Correlation-induced spectral changes显示文摘 | Wolf E James D F V | 1996 | Rep Prog Phys1996，59，： | 1 |
| 9 | Comparison and evaluation of methods for liver segmentation from CT datasets显示文摘 | Heimann T van Ginneken B Styner MA Arzhaeva Y Aurich V Bauer C Beck A Becket C Beichel R Bekes G Bello F Binnig G Bischof H Bornik A Cashman PM Chi Y Cordova A Dawant BM Fidrich M Furst JD Furukawa D Grenacher L Hornegger J Kainmuller D Kitney RI Kobatake H Lamecker H Lange T Lee J Lennon B Li R Li S Meinzer HP Nemeth G Raicu DS Rau AM van Rikxoort EM Rousson M Rusko L Saddi KA Schmidt G Seghers D Shimizu A Slagmolen P Sorantin E Soza G Susomboon R Waite JM Wimmer A Wolf I | 2009 | IEEE Transactions on Medical Imaging2009，28，8： | 1 |
| 10 | Right heart dilatation in adult congenital heart disease:imaging appearance on cardiac magnetic resonance显示文摘 | Beitzke D Wolf F Edelhauser G | | British Journal of Radiology0，，： | 1 |
| 11 | Dynamic stability of a nonrigid parachute and payload system显示文摘 | WOLF D F | 1971 | Journal of Aircraft1971，8，8： | 1 |
| 12 | Dielectric properties forevaluating apple maturity显示文摘 | Wolf D F Zacha riah G L | 1973 | Transactions of the ASAE1973，16，5： | 1 |
| 13 | Eye-to-hand coordination for vision-guided robot control application 显示文摘 | Wijiesoma S W Wolfe D F H Richards R J | 1993 | Int J of Robotics Research1993，12，1： | 1 |
| 14 | Local Convective HeatTransfer From a Heated Surface to a Planar Jet of Water With aNonuniform Velocity Profile显示文摘 | Wolf D H Viskanta R Incropera F P | 1990 | Journal of Heat Transfer1990，112，11： | 1 |
| 15 | Local jet impingement boiling heat transfer显示文摘 | Incropera F P Viskanta R | 1996 | Int J Heat Mass Transfer1996，39，7： | 1 |
| 16 | Achieving sub-pixel geolocation accuracy in support of MODIS land science 显示文摘 | WOLFE R E NISHIHAMA M FLEIG A J KUYPER J A ROY D P STOREY J C PATF F S | 2002 | Remote Sensing of Environment2002，83，： | 1 |
| 17 | Load-displacement behavior in a distal radius fracture mode the effect of simulated healing on motion显示文摘 | Wolfe F W Lorenze M D Ausn G | 1999 | J bone Joint Surg AM1999，81，1： | 1 |
| 18 | Hypoxemia of cirrhosis:detectionof abnormal small pulmonary vascular channels by a quantitative radionuclide method显示文摘 | Wolfe J D Tashkin D P Holly F E | 1977 | Am J Med1977，63，： | 1 |
| 19 | The methyl - CpG - binding protein MeCP2 links DNA methylation to his- tone methylation 显示文摘 | Fuks F Hurd P J Wolf D | 2003 | Journal of Biological Chemistry2003，278，6： | 1 |
| 20 | The association a- mong childhood maltreatment, somatic symptom intensity, depression,and somatoform dissociative symptoms in pa- tients with fibromyalgia syndrome:a single-center cohort study 显示文摘 | Bohnab D Bernardy K Wolfe F | 2013 | Journal of Trauma & Dissociation2013，14，3： | 1 |
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