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| 1 | New kinematic structures for2-, 3-, 4-, and 5-DOF parallel manipulator designs显示文摘 | FengG WeiM L Xian C Z | 2002 | Mecha- nism and Machine Theory2002，37，： | 1 |
| 2 | Effect of recombinant human growth hormone and enteral nutrition on short bowel syndrome显示文摘 | Weiming Z Ning L Jieshou L | 2004 | JPEN J Parenter Enteral Nutr2004，28，6： | 1 |
| 3 | Norovirus and histoblood group antigens: Demonstration of a wide spectrum of strain specificities and classification of two major binding groups among multiple binding patterns显示文摘 | Pengwei H Tibor F Weiming Z | 2005 | J Virol2005，79，11： | 1 |
| 4 | Stochastic seismic analysis of a concrete-filled steel tubular(CFST) arch bridge under tridirectional multiple excitations显示文摘 | Deyi Z Xi L Weiming Y | | 0，，： | 1 |
| 5 | Clinical analysis of West syndrome associated with phenylketonuria显示文摘 | Zhongshu Z Weiming Y Yukio F | 2001 | Brain Dev2001，23，： | 1 |
| 6 | Serum citrulline is a sim-ple quantitative marker for small intestinal enterocytes mass andabsorption function in short bowel patients 显示文摘 | Jianfeng G Weiming Z Ning L | 2005 | J Surg Res2005，127，2： | 1 |
| 7 | The tribological properties of diethylamm-onium lanthanide tetrakis (diethyldithioearbamate) in lubrica ting oil 显示文摘 | Zefu Z Weiming L Qunji X | 1998 | Lubrication Science1998，10，3： | 1 |
| 8 | Processing recursive XQuery over XML streams: The Raindrop approach 显示文摘 | Weim M Z Rundensteiner E A Mani M | 2008 | Data & Knowledge Engineering2008，65，： | 1 |
| 9 | Microbial Cellulose Utilization:Fundamentals and Biotechnology显示文摘 | LYND LR WEIM PJ WILLEM Z | 2002 | Microbiol Mol Biol Rev2002，66，： | 1 |
| 10 | Serum citrulline is a sim-ple quantitative marker for small intestinal enterocytes mass andabsorption function in short bowel patients 显示文摘 | Jianfeng G Weiming Z Ning L | 2005 | J Surg Res2005，127，2： | 1 |
| 11 | Serum citrulline isa simple quantitative marker for small intestinal enterocytesmass and absorption function in short bowel patients显示文摘 | Jianfeng G Weiming Z Ning L | 2005 | JSurg Res2005，127，2： | 1 |
| 12 | Microbial Cellulose Utilization: Fundamentals and Biotechnology 显示文摘 | Lynd L R Weim P J Willem Z | 2002 | Microbiol Mol Biol Rev2002，66，： | 1 |
| 13 | Synthesis and structure of molecular tweezers containing active site functionality显示文摘 | Zimmerman S C Zeng Z Weiming W | 1991 | J Am Chem Soc1991，113，1： | 1 |
| 14 | Fibromodulin reduces scar formation in adult cutaneouswounds by eliciting a fetal-like phenotype显示文摘Blocking transforming growth factor(TGF)β1 signal transduction has been a central strategy for scar reduction;however,this approach appears to be minimally effective.Here,we show that fibromodulin(FMOD),a 59-kD small leucine-rich proteoglycan critical for normal collagen fibrillogenesis,significantly reduces scar formation while simultaneously increasing scar strength in both adult rodent models and porcine wounds,which simulate human cutaneous scar repair.Mechanistically,FMOD uncouples promigration/contraction cellular signals from pro-fibrotic signaling by selectively enhancing SMAD3-mediated signal transduction,while reducing AP-1-mediated TGFβ1 auto-induction and fibrotic extracellular matrix accumulation.Consequently,FMOD accelerates TGFβ1-responsive adult fibroblast migration,myofibroblast conversion,and function.Furthermore,our findings strongly indicate that,by delicately orchestrating TGFβ1 activities rather than indiscriminately blocking TGFβ1,FMOD elicits fetal-like cellular and molecular phenotypes in adult dermal fibroblasts in vitro and adult cutaneous wounds in vivo,which is a unique response of living system undescribed previously.Taken together,this study illuminates the signal modulating activities of FMOD beyond its structural support functions,and highlights the potential for FMOD-based therapies to be used in cutaneous wound repair. | Zhong Zheng Aaron W James Chenshuang Li Wenlu Jiang Joyce Z Wang Grace X Chang Kevin S Lee Feng Chen Emily A Berthiaume Yao Chen Hsin Chuan Pan Eric C Chen Weiming Li Zhihe Zhao Xinli Zhang Kang Ting Chia Soo | 2017 | Signal Transduction and Targeted Therapy2017，2，1： | 0 |
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