|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Precise orbit determination of Beidou Satellites with precise positioning显示文摘Chinese Beidou satellite navigation system constellation currently consists of eight Beidou satellites and can provide preliminary service of navigation and positioning in the Asia-Pacific Region.Based on the self-developed software Position And Navigation Data Analysis(PANDA) and Beidou Experimental Tracking Stations (BETS),which are built by Wuhan University,the study of Beidou precise orbit determination,static precise point positioning (PPP),and high precision relative positioning,and differential positioning are carried out comprehensively.Results show that the radial precision of the Beidou satellite orbit determination is better than 10 centimeters.The RMS of static PPP can reach several centimeters to even millimeters for baseline relative positioning.The precision of kinematic pseudo-range differential positioning and RTK mode positioning are 2-4 m and 5-10 cm respectively,which are close to the level of GPS precise positioning.Research in this paper verifies that,with support of ground reference station network,Beidou satellite navigation system can provide precise positioning from several decimeters to meters in the wide area and several centimeters in the regional area.These promising results would be helpful for the implementation and applications of Beidou satellite navigation system. | SHI Chuang ZHAO QiLe LI Min TANG WeiMing HU ZhiGang LOU YiDong ZHANG HongPing NIU XiaoJi LIU JingNan | 2012 | Science China Earth Sciences2012，55，7： | 61 |
| 2 | Early Paleozoic subduction of the Paleo-Asian Ocean: Geochronological and geochemical evidence from the Dashizhai basalts, Inner Mongolia显示文摘Zircon U-Pb results of basalt from the Dashizhai Town in Inner Mongolia, NE China, shows that the basaltic lava was erupted at 439±3 Ma, much older than the 'Permian basalts' as previously thought. These rocks show arc-type trace element patterns (i.e., Nb-Ta depletion and light REE and large ion lithophile element enrichment) and unradiogenic Sr and highly radiogenic Nd and Hf isotope compositions. They can be subdivided into two petrogenetic groups: Group 1 basalts have relatively high TiO2, MgO and compatible elements and low Sr and Th, characterized by mid-oceanic ridge basalt (MORB)-type Sr-Nd-Hf isotope compositions (87Sr/86Sr(i)=0.7028―0.7032, εNd(t)=+9.8-+11.2, εHf(t)=+16.1- +18.4). Group 2 has lower TiO2, MgO and compatible elements and higher Sr and Th, and relatively evolved Sr-Nd-Hf isotope compositions (87Sr/86Sr(i)=0.7037-0.7038, εNd(t)=+5.7-+7.3, εHf(t)=+12.6- +13.0). Both groups were interpreted as melts derived from a metasomatized mantle wedge formed during the subduction of Paleo-Asian Ocean. The mantle source for Group 1 was probably a highly isotopically depleted oceanic mantle modified by predominant slab fluids; whereas subducted sediments had an important contribution to the melting source for Group 2. The petrogenesis of the Dashizhai basalts provides clear evidence for early Paleozoic subduction of the Paleo-Asian Ocean, and the highly radiogenic Nd and Hf compositions in these rocks suggest that these lavas and their possible intrusive counterparts were one of the important components for Phanerozoic crustal growth. Our and previous studies on the 'Dashizhai Formation' volcanic rocks yield an unrealistic eruption range of 440-270 Ma for different rock types, we thus advise to disassemble the previously defined 'Dashizhai Formation' into multiple lithologic units and to reinterpret the spatial and temporal distributions of different volcano-sedimentary associations. | GUO Feng FAN WeiMing LI ChaoWen MIAO LaiCheng ZHAO Liang | 2009 | Science China Earth Sciences2009，52，7： | 37 |
| 3 | Structure and contents of layered classification system of digital geomorphology for China显示文摘这份报纸为中国论述数字地形学的一个标准化分层的分类系统的结构和内容。这个数字分类方法把形态学的地形特征与开始相结合。exogenic 和 endogenic 力量的 15 个范畴的一个总数被划分成二个宽广范畴:形态基因、 morpho 结构的地形。多角形补丁被用来管理形态基因的类型,并且独居的点,线和多角形被用来管理 morpho 结构的类型。数字形态基因的类型的分类方法能被划分成七层,即基本形态学和高度,开始,亚开始,形态学,微形态学,斜坡和方面,材料和岩性学。方法基于分层的指示物建议矩阵形式的联合。每种地形类型的属性从所有七层或一些被获得。为 15 个力量范畴,一些分类指示物和计算方法为基本形态学被介绍,词法并且形态基因的类型的亚 morphologic 地形。独居的多角形,线性并且 morpho 结构的地形的点类型分别地被介绍。分层的分类方法能遇见从 1:500,000 为国家主要规模印射到 1:1,000,000 的规模跨度 geomorphologic 的要求。层用作分类指示物,并且能因此根据印射要求被增加并且减少,提供灵活 expandability。 | CHENG Weiming ZHOU Chenghu LI Bingyuan SHEN Yuancun ZHANG Baiping | 2011 | Journal of Geographical Sciences2011，21，5： | 26 |
| 4 | Crustal evolution of the Shiwandashan area in South China:Zircon U-Pb-Hf isotopic records from granulite enclaves in Indo-Sinian granites显示文摘标明日期的 U-Pb 在东南的 Guangxi 省从 Shiwandashan 区域在 Jiuzhou peraluminous 花岗石从 metasedimentary granulite 被外国领地包围的土地在锆石上结合了 Hf 同位素分析,华南在这份报纸被介绍。结果证明这些 granulite 被外国领地包围的土地的 protoliths 主要由有一座山峰的碎屑状的材料在 822 妈变老的 Neo-Mesoproterozoic (5641061 妈) 组成。这些材料可能从在 Rodinian Supercontinent 的 Neoproterozoic 决裂期间是 emplaced 的火的岩石被导出。辅助沉积包括 Paleoproterozoic (17782227 妈) ,有最旧的 U-Pb 的甚至 Meso-Paleoarchean 材料在 3551 | ZHAO Liang GUO Feng FAN WeiMing LI ChaoWen QIN XiaoFeng LI HongXia | 2010 | Chinese Science Bulletin2010，55，19： | 18 |
| 5 | Ar-Ar geochronology of Late Mesozoic volcanic rocks from the Yanji area, NE China and tectonic implications显示文摘Ar-Ar dating results of late Mesozoic-Cenozoic volcanic rocks from the Yanji area, NE China provide a new volcano-sedimentary stratigraphic framework. The previously defined “Triassic-Jurassic” volcanic rocks (including those from Sanxianling, Tuntianying, Tianqiaoling and Jingouling Fms.) were erupted during 118―106 Ma, corresponding to Early Cretaceous. The new eruption age span is slightly younger than the main stage (130―120 Ma) of the extensive magmatism in the eastern Central Asian Orogenic Belt and its adjacent regions. Subduction-related adakites occurring in the previously defined Quanshuicun Fm. were extruded at ca. 55 Ma. Based on these new Ar-Ar ages, the late Mesozoic to Palaeocene volcano-sedimentary sequences is rebuilt as: Tuopangou Fm., Sanxianling/Tuntianying Fm. (118―115 Ma), Malugou/Tianqiaoling Fm. (K1), Huoshanyan/Jingouling Fm. (108―106 Ma), Changcai Fm. (K2), Quanshuicun Fm. (~55 Ma) and Dalazi Fm. Our results suggest that subduction of the Pa- laeo-Pacific Ocean beneath the East Asian continental margin occurred during 106 to 55 Ma, consistent with the paleomagnetic observations and magmatic records which indicated that the Izanagi-Farallon ridge subduction beneath the southwestern Japan took place during 95―65 Ma. | LI ChaoWen GUO Feng FAN WeiMing GAO XiaoFeng | 2007 | Science China Earth Sciences2007，50，4： | 15 |
| 6 | Optimization of flue gas convective heat transfer with condensation in a rectangular channel显示文摘Conservation equations of sensible entarnsy and latent entransy are established for flue gas convective heat transfer with condensation in a rectangular channel and the entransy dissipation expression is deduced.The field synergy equation is obtained on the basis of the extremum entransy dissipation principle for flue gas convective heat transfer with condensation.The optimal velocity field is numerically obtained by solving the field synergy equation.The results show that the optimal velocity field has multiple longitudinal vortices,which improve the synergy not only between the veloctiy and temperature fields but also between the velocity and vapor concentration fields.Therefore,the convective heat and mass transfers are significantly enhanced.Flow with multiple longitudinal vortices close to the optimal velocity field can be generated by discrete double-inclined ribs set in the rectangular channel.The numerical results show that the total heat transfer rate in the discrete double-inclined rib channel increases by 29.02% and the condensing heat transfer rate increases by 27.46% for Re = 600 compared with the plain channel. | SONG WeiMing MENG JiAn LI ZhiXin | 2011 | Chinese Science Bulletin2011，56，3： | 14 |
| 7 | New Trends in Intelligent Manufacturing显示文摘Intelligent manufacturing technology has become a major trend in the development of the manufacturing industry around the world,and is being studied and applied by numerous industrially developed countries.For example,the United States has proposed an intelligent manufacturing layout based on the Industrial Internet and the‘‘New Generation of Robots”;Germany has proposed the Industry 4.0 initiative to boost the competitiveness of the manufacturing industry through intelligent manufacturing;and the European Union(EU),Japan,Korea,China,and other large manufacturing countries have put forward corresponding strategies for the development of intelligent manufacturing.Clearly,intelligent manufacturing has become an important direction in the development of the manufacturing industry. | Liang Gao Weiming Shen Xinyu Li | 2019 | Engineering2019，5，4： | 14 |
| 8 | Enhanced debromination of 4-bromophenol by the UV/sulfite process:Efficiency and mechanism显示文摘Halogenated aromatic compounds have attracted increasing concerns due to their toxicity and persistency in the environment, and dehalogenation is one of the promising treatment and detoxification methods. Herein, we systematically studied the debromination efficiency and mechanism of para-bromophenol(4-BP) by a recently developed UV/sulfite process. 4-BP underwent rapid degradation with the kinetics accelerated with the increasing sulfite concentration, pH(6.1–10) and temperature, whereas inhibited by dissolved oxygen and organic solvents. The apparent activation energy was estimated to be 27.8 kJ/mol. The degradation mechanism and pathways of 4-BP were explored by employing N_2O and nitrate as the electron scavengers and liquid chromatography/mass spectrometry to identify the intermediates. 4-BP degradation proceeded via at least two pathways including direct photolysis and hydrated electron-induced debromination. The contributions of both pathways were distinguished by quantifying the quantum yields of 4-BP via direct photolysis and hydrated electron production in the system. 4-BP could be readily completely debrominated with all the substituted Br released as Br-, and the degradation pathways were also proposed. This study would shed new light on the efficient dehalogenation of brominated aromatics by using the UV/sulfite process. | Bihuang Xie Xuchun Li Xianfeng Huang Zhe Xu Weiming Zhang Bingcai Pan | 2017 | Journal of Environmental Sciences2017，29，4： | 12 |
| 9 | Inhibition of lung cancer cell proliferation mediated by human mesenchymal stem cells显示文摘人的间充质的干细胞(hMSCs ) 主要为他们的潜在的临床的使用被学习。最近,癌症研究的领域里的许多注意对 hMSCs 被给予了。在这研究,我们由使用一个合作文化系统和调节 hMSCs 的媒介在 vitro 并且在 vivo 在肺癌症房间线 SK-MES-1 和 A549 的增长上调查了 hMSCs 的影响。我们的结果证明 hMSCs 能禁止 SK-MES-1 和 A549 房间的增长,并且经由一些可溶的因素在 vitro 导致肿瘤房间的 apoptosis。动物学习证明从 hMSCs 的这些可溶的因素能由 preliminarily 与调节 hMSCs 的媒介对待肿瘤细胞压制 tumorigenesis 和肿瘤 angiogenesis。在肿瘤房间的脉管的 endothelial 生长因素的 downregulated 表示可能是在肿瘤 angiogenesis 的干扰的机制,它被西方的污点分析和 immunohistochemistry 试金验证。一起拿,我们的结果建议 hMSCs 能由 secreting 一些禁止肿瘤细胞生长可溶的因素。 | Lin Li Hui Tian Zhitao Chen Weiming Yue Shuhai Li Wenjun Li | 2011 | Acta Biochimica et Biophysica Sinica2011，43，2： | 11 |
| 10 | Investigation Into the Electromagnetic Impulses From Long- Pulse Laser Illuminating Solid Targets Inside a Laser Facility显示文摘电磁的脉搏(EMP ) 的排放在这个工作用一条锥天线由于在激光设备的激光目标相互作用被评估了。当有几几千焦耳的长脉搏的激光照亮了稳固的目标时,在从几百 MHz 到 2 GHz 的频率的微波被记录,同时,到 4 V 的从 1 V 的电压信号作为激光精力和背光激光的函数被捕获,在相应电场力量被与进行数学进程(有 L 曲线的 Tiknohov 规则化)在联合模仿锥天线获得的地方。所有典型联合电压摆动显示了多重山峰并且在腐烂进 EMP 产生的噪音和机制前有多达 80 ns 的持续时间图解地在实际测量环境的基础被解释。结果的数据被期望提供基本诀窍完成惯性的监禁熔化。 | Tao YI Jinwen YANG Ming YANG Chuanke WANG Weiming YANG Tingshuai LI Shenye LIU Shaoen JIANG Yongkun DING Shaoqiu XIAO | 2016 | Photonic Sensors2016，6，3： | 11 |
| 11 | High-Performance Flexible Asymmetric Supercapacitor Based on CoAl-LDH and rGO Electrodes显示文摘A flexible asymmetric supercapacitor(ASC)based on a Co Al-layered double hydroxide(Co Al-LDH)electrode and a reduced graphene oxide(r GO) electrode was successfully fabricated. The Co Al-LDH electrode as a positive electrode was synthesized by directly growing Co Al-LDH nanosheet arrays on a carbon cloth(CC)through a facile hydrothermal method, and it delivered a specific capacitance of 616.9 F g^(-1)at a current density of1 A g^(-1). The r GO electrode as a negative electrode was synthesized by coating r GO on the CC via a simple dipcoating method and revealed a specific capacitance of110.0 F g^(-1)at a current density of 2 A g^(-1). Ultimately,the advanced ASC offered a broad voltage window(1.7 V)and exhibited a high superficial capacitance of1.77 F cm^(-2)at 2 m A cm^(-2)and a high energy density of0.71 m Wh cm^(-2)at a power density of 17.05 m W cm^(-2),along with an excellent cycle stability(92.9% capacitance retention over 8000 charge–discharge cycles). | Shuoshuo Li Pengpeng Cheng Jiaxian Luo Dan Zhou Weiming Xu Jingwei Li Ruchun Li Dingsheng Yuan | 2017 | Nano-Micro Letters2017，9，3： | 10 |
| 12 | WheatOmics:A platform combining multiple omics data to accelerate functional genomics studies in wheat显示文摘Dear Editor,Mold-breaking progress in whole-genome sequencing and rapid accumulation of multi-omics data have revolutionized the research strategies of functional genomics in wheat(Wang et al.,2018).However,how to access these vast multi-omics data and to extract key information on genes of in-terest,is still challenging for most wet-lab or field wheat re-searchers who have little bioinformatic experiences and cannot access the expensive computational resources.Here,we pre-sent WheatOmics(http://gffzz513af15b15bc4712hbwvnnqqu5wfq69wk.ffgz.tsg.suse.edu.cn/,previously designated as Triticeae Multi-omics Center,http://gffzz601e21d286504235hbwvnnqqu5wfq69wk.ffgz.tsg.suse.edu.cn/),a free,web-accessible,and user-friendly platform.WheatOmics not only empowers the effective access to the visualized multi-omics data of user-interested genes but also offers several distinctive and practical toolkits that can ease almost every aspect of wheat functional genomics studies(Figure 1A). | Shengwei Ma Meng Wang Jianhui Wu Weilong Guo Yongming Chen Guangwei Li Yanpeng Wang Weiming Shi Guangmin Xia Daolin FU Zhensheng Kang Fei Ni | 2021 | Molecular Plant2021，14，12： | 9 |
| 13 | Monoclonal Antibody-Based Enzyme Linked Immunosorbent Assay for the Analysis of Jasmonates in Plants显示文摘Methyl jasmonate (MeJA) and its free-acid form, jasmonic acid (JA) are naturally occurring plant growth regulators widely distributed in higher plants. In order to improve the sensitivity for the analysis of MeJA at low levels in small amounts of plant samples, a monoclonal antibody (MAb) (designated as MAb 3E5D7C4B6) against MeJA was derived from a JA-bovine serum albumin (BSA) conjugate as an immunogen. The antibody belongs to the IgG1 subclass with a κ type light chain and has a dissociation constant of approximately 6.07 × 10?9 M. MAb3E5D7C4B6 is very specific to MeJA. It was used to develop a direct competitive enzyme-linked immunosorbent assay (dcELISA), conventional and simplified indirect competitive ELISAs (icELISA). JA was derivatized into MeJA for the ELISA analysis. The IC50 value and detection range for MeJA were, respectively, 34 and 4-257 ng/mL by the conventional icELISA, 21 and 3-226 ng/mL by the simplified icELISA and 5.0 and 0.7-97.0 ng/mL by the dcELISA. The dcELISA was more sensitive than either the conventional or simplified icELISA. The assays were used to measure the content of jasmonates as MeJA in tobacco leaves under drought stress or inoculated with tobacco mosaic virus and tomato leaves inoculated with tomato mosaic virus or Lirioinyza sativae Blanchard as compared with the corresponding healthy leaves. The increased jasmonates content indicated its role in response to the drought stress and pathogens. | Aixing Deng Weiming Tan Suping He Wei Liu Tiegui Nan Zhaohu Li Baomin Wang Qing X. Li | 2008 | Journal of Integrative Plant Biology2008，50，8： | 9 |
| 14 | Platelet function monitoring guided antiplatelet therapy in patients receiving high-risk coronary interventions显示文摘 | Xu Li Wang Lefeng Yang Xinchun Li Kuibao Sun Hao Zhang Dapeng Wang Hongshi Li Weiming Ni Zhuhua Xia Kun Liu Yu | 2014 | Chinese Medical Journal2014，，19： | 8 |
| 15 | Impacts of ionospheric scintillation on geosynchronous SAR focusing: preliminary experiments and analysis显示文摘亲爱的编辑,同步合成孔径雷达(GEO SAR)具有显着的潜在危害和灾害监测应用时,由于其短重访时间约24小时,约1 / 3的地球表面[1,2],覆盖面广。然而,在L波段操作使它更容易受到电离层闪烁[2,3]。徐等。从理论上分析了电离层对星载SAR球形闪烁[ 3 ]的影响,这一现象也被观察到在低地球轨道(LEO SAR)SARS如ALOS PALSAR [ 4 ]。地理合成孔径雷达是更严重的影响电离层闪烁,因为信号传播路径覆盖整个电离层(超过1000公里以上的地面)[ 3 ]。相比之下,狮子座合成孔径雷达的轨道是几百公里。然而,研究人员很少分析电离层闪烁对L波段GEO SAR,或进行实验验证。 | LI YuanHao HU Cheng DONG XiChao TIAN WeiMing LONG Teng | 2015 | Science China(Information Sciences)2015，58，10： | 8 |
| 16 | Identification of the lower limit of high-quality source rocks and its relation to hydrocarbon accumulation——Taking the Beier Sag in the Hailaer Basin as an example显示文摘The theory of 'source rock control' has evolved from source-rock-control hydrocarbon accumulation, to effective source-rock-control hydrocarbon accumulation, and to high-quality source-rock-control hydrocarbon accumulation. However, there are problems, such as whether high-quality source rocks exist or not? What high-quality source rocks are, and how to identify them, are yet to be agreed upon. Aimed at this issue of concern to explorationists, and taking the Beier Sag in the Hailaer Basin as an example, this paper defines the high-quality source rocks and the lower limit for evaluation of high-quality source rocks, by using the inflection point on the relationship curve of hydrocarbon (oil) expulsion, which is calculated by the material balance principle, versus total organic carbon (TOC). The results show that when TOC is low, all source rocks have limited hydrocarbon expulsion and slow growth rate, thus they cannot be high-quality source rocks. However, when TOC rises to some threshold, hydrocarbon expulsion increases significantly with TOC. This inflection point should be the lower limit of high-quality source rocks: those with TOC greater than the inflection-point value are high-quality source rocks. In addition, the lower limit of high-quality source rocks is also related to the type and maturity of organic matters in the source rocks, as well as the mineral components of the source rocks affecting the residual hydrocarbons. Theoretically, the lower limit of high-quality source rocks depends on geological conditions rather than being a constant value. However, for the sake of simplicity and practicability, in this paper TOC=2.0% is regarded as the lower limit of high-quality source rocks. The examination of such standard in the work area indicates that the high-quality source rocks in members K 1 n 2 and K 1 n 1 of the Nantun formation contribute 76% and 82% to oil generation, and 96% and 91% to oil expulsion , respectively. The distribution of high-quality source rocks is also closely related to the distribution of hydrocarbon reservoirs in the region, demonstrating that high-quality source rocks control hydrocarbon accumulation. | Lu Shuangfang Chen Fangwen Li Jijun Wang Weiming Li Huiguang Cao Ruicheng Ma Yanling | 2012 | Petroleum Science2012，9，1： | 7 |
| 17 | Mitochondrial DNA A1555G mutation screening using a testing kit method and its significance in preventing aminoglycoside-related hearing loss显示文摘To report a new screening method for mitochondrial DNA 1555A→G mutation and the results of genotype analysis in 19 maternal inherited deafness pedigrees. Method Five hundred and forty-six non-syndromic neuro-sensory hearing loss patients were tested for 1555A→G mutation using a new compact testing kit, which allows clear distinction between wild type and 1555 A→G mutated mtDNAs. Results Nineteen subjects among the 546 patients (3.48%) were found to carry mtDNA A1555G mutation. The results were confirmed by sequencing in an ABI 3100 Avant sequencer. Conclusions Maternal inherited deafness families are a frequently seen in outpatient group. The detection of mtDNA 1555 A→G mutation with a low cost, ready to use detection kit is needed and suitable in China for large scale screening and preventive testing before usage of aminoglycoside antibiotics. | LIU Xin,1 DAI Pu,1* HUANG Deliang,1 YUAN Huijun,1 LI Weiming,1 YU Fei,1 ZHANG Xin,1 KANG Dongyang,1 CAO Juyang,1 YANG Weiyan,1 HAN Dongyi,1 JIN Zhengce2, GUAN Minxin3 1. Department of Otolaryngology, Chinese PLA General Hospital, Beijing, China2. Weihai Aomaier Gene Technological CO.,LTD.,Weihai,Shandong 264200, China.3. Division and Program in Human Genetics and Center for Hearing and Deafness Research, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA | 2006 | Journal of Otology2006，1，1： | 7 |
| 18 | Preparation and activity evaluation of NiMoB/-Al_2O_3 catalyst by liquid-phase furfural hydrogenation显示文摘Amorphous MoNiB/ -Al 2 O 3 alloy catalysts were prepared by reducing NiCl 2 ·6H 2 O and (NH 4 ) 6 Mo 7 O 24 ·4H 2 O supported on -Al 2 O 3 with NaBH 4 as reducing agent. Using liquid-phase hydro-genation of furfural (FFR) as a probe reaction, the activity of MoNiB/ -Al 2 O 3 was examined. Compared to NiB and NiMoB, NiMoB/ -Al 2 O 3 exhibited excellent activity and selectivity towards furfuryl alcohol (FFA). After reaction for 3.0 h at 80 ℃ and 5.0 MPa in methanol, FFR conversion reached 99% with FFA yield of 91%. The effects of doping amount of Mo and calcination temperature before NaBH 4 reduction on hydrogenation activity were also investigated. The optimum Mo/Ni atom ratio and calcination temperature were found to be 1:7 and 300 ℃, respectively. XRD patterns and SEM images indicated that NiMoB over the surface of -Al 2 O 3 was amorphous and highly dispersed, which was responsible for the high thermal stability of the title catalyst. | Shuqin Wei Hongyou Cui Jinghua Wang Shuping Zhuo Weiming Yi Lihong Wang Zhihe Li | 2011 | Particuology2011，9，1： | 7 |
| 19 | Effects of Sini San used alone and in combination with fluoxetine on central and peripheral 5-HT levels in a rat model of depression显示文摘OBJECTIVE: To investigate the effects of Sini San and fluoxetine on the levels of central and peripheral 5-HT in a rat model of depression, and provide new insight into the treatment of depression with integrated Chinese-Western Medicine.METHODS: A rat model of depression was established by chronic mild stress(CMS). Model rats received either Sini San, fluoxetine, a combination of the two drugs, or no drug treatment. Healthy naive rats were used as controls. Open field and sucrose preference tests were used to assess depression-like behavior. ELISA and immunohistochemistry were used to determine central and peripheral levels of 5-HT.RESULTS: In the group with no drug treatment,central 5-HT expression decreased while peripheral5-HT concentrations increased as CMS continued.Four weeks after CMS, Sini San alone was less effective in reducing depression-like behavior than fluoxetine alone or in combination with Sini San,but combined use was more effective than fluoxetine alone. Eight weeks after CMS, Sini San alone or in combination with fluoxetine was more effective in reducing depression-like behavior than fluoxetine alone. Furthermore Sini San and fluoxetine used alone or in combination notably increased central 5-HT expression and decreased peripheral 5-HT levels in the rat model.CONCLUSION:The results of the present study indicate that there is a synergistic action between the two medicines in the treatment of depression. Sini San exhibited a relatively long lag before its effects were observed; however, by eight weeks the Traditional Chinese Medicine appeared at least as effective as fluoxetine. We suggest that Sini San can replace fluoxetine in the later stages of depression treatment to minimize side effects observed with long-term fluoxetine administration. | Yubo Li Yuxiu Sun Xueling Ma Xiaoxing Xue Wenting Zhang Zhiqian Wu Yulin Ouyang Jianxin Chen Weiming Wang Shuzhen Guo Wei Wang | 2013 | Journal of Traditional Chinese Medicine2013，33，5： | 6 |
| 20 | Isolation of candidate R disease resistance genes from rice显示文摘Using a polymerase chain reaction (PCR) based method six distinct candidate disease resistant gene (R) homologs from rice have been isolated. The rice sequences are organized into two phylogenetic groups with contrasting genomic organization patterns. The first group, represented by a single sequence, Osh359-1, is more similar to non-rice R sequences than to rice ones and has a simple genomic organization. The second group, represented by Osh359-3, contains the remaining five rice sequences. Osh359-3 consists of a multi-gene family. The members of Osh359-3 family are further found to be clustered together in the genome. | Yongbiao Xue Dingzhong Tang Yansheng Zhang Weiming Li | 1998 | Chinese Science Bulletin1998，43，6： | 6 |
您所在的机构暂未开通此部分的功能，请联系管理员