|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Synthetical Efficiency-based Optimization for the Power Distribution of Power-split Hybrid Electric Vehicles显示文摘Now the optimization strategies for power distribution are researched widely,and most of them are aiming to the optimal fuel economy and the driving cycle must be preknown.Thus if the actual driving condition deviates from the scheduled driving cycle,the effect of optimal results will be declined greatly.Therefore,the instantaneous optimization strategy carried out on-line is studied in this paper.The power split path and the transmission efficiency are analyzed based on a special power-split scheme and the efficiency models of the power transmitting components are established.The synthetical efficiency optimization model is established for enhancing the transmission efficiency and the fuel economy.The identification of the synthetical efficiency as the optimization objective and the constrain group are discussed emphatically.The optimization is calculated by the adaptive simulated annealing(ASA)algorithm and realized on-line by the radial basis function(RBF)-based similar models.The optimization for power distribution of the hybrid vehicle in an actual driving condition is carried out and the road test results are presented.The test results indicate that the synthetical efficiency optimization method can enhance the transmission efficiency and the fuel economy of the power-split hybrid electric vehicle(HEV)observably.Compared to the rules-based strategy the optimization strategy is optimal and achieves the approximate global optimization solution for the power distribution.The synthetical efficiency optimization solved by ASA algorithm can give attentions to both optimization quality and calculation efficiency,thus it has good application foreground for the power distribution of power-split HEV. | WANG Weida HAN Lijin XIANG Changle MA Yue LIU Hui | 2014 | Chinese Journal of Mechanical Engineering2014，27，1： | 12 |
| 2 | Sequential fate-switches in stem-like cells drive the tumorigenic trajectory from human neural stem cells to malignant glioma显示文摘Glioblastoma(GBM)is an incurable and highly heterogeneous brain tumor,originating from human neural stem/progenitor cells(hNSCs/hNPCs)years ahead of diagnosis.Despite extensive efforts to characterize hNSCs and end-stage GBM at bulk and single-cell levels,the de novo gliomagenic path from hNSCs is largely unknown due to technical difficulties in early-stage sampling and preclinical modeling.Here,we established two highly penetrant hNSC-derived malignant glioma models,which resemble the histopathology and transcriptional heterogeneity of human GBM.Integrating time-series analyses of whole-exome sequencing,bulk and single-cell RNA-seq,we reconstructed gliomagenic trajectories,and identified a persistent NSC-like population at all stages of tumorigenesis.Through trajectory analyses and lineage tracing,we showed that tumor progression is primarily driven by multi-step transcriptional reprogramming and fate-switches in the NSC-like cells,which sequentially generate malignant heterogeneity and induce tumor phenotype transitions.We further uncovered stage-specific oncogenic cascades,and among the candidate genes we functionally validated C1QL1 as a new glioma-promoting factor.Importantly,the neurogenic-to-gliogenic switch in NSC-like cells marks an early stage characterized by a burst of oncogenic alterations,during which transient AP-1 inhibition is sufficient to inhibit gliomagenesis.Together,our results reveal previously undercharacterized molecular dynamics and fate choices driving de novo gliomagenesis from hNSCs,and provide a blueprint for potential early-stage treatment/diagnosis for GBM. | Xiaofei Wang Ran Zhou Yanzhen Xiong Lingling Zhou Xiang Yan Manli Wang Fan Li Chuanxing Xie Yiming Zhang Zongyao Huang Chaoqiong Ding Kaidou Shi Weida Li Yu Liu Zhongwei Cao Zhen-Ning Zhang Shengtao Zhou Chong Chen Yan Zhang Lu Chen Yuan Wang | 2021 | Cell Research2021，31，6： | 8 |
| 3 | Roles of fishing and climate change in long-term fish species succession and population dynamics in the outer Beibu Gulf,South China Sea显示文摘A prevailing,controversial hypothesis is that fishing pressure has played a greater role than climatic and environmental drivers,in changing fish species succession and biomass fluctuation in the South China Sea(SCS).Based on otter trawl survey data from 1959 to 2010 in the outer Beibu Gulf(OBG),northern SCS,large seasonal and interannual variation is reported for fish species composition,the proportional abundances of dominant taxa,and fish biomass.Generalized additive models are developed to quantify relationships between fish biomass and the external factors of fishing pressure and climate change.Fishing pressure proved to be the main driver of sharp declines in demersal fish stocks,with high-value species being replaced by low-value ones over time.Abrupt decreases in fish biomass during the years of 1993 and 1998 correspond to El Nino events,with climate change possibly the main driver of proportional representation of pelagic species in fisheries trawl catch.The need to differentiate impacts of fishing and environmental drivers on fish species with different life history strategies is stressed to better understand fish community dynamics. | Xuehui Wang Yongsong Qiu Feiyan Du Weida Liu Dianrong Sun Xiao Chen Weiwen Yuan Yong Chen | 2019 | Acta Oceanologica Sinica2019，38，10： | 6 |
| 4 | Dynamic Stability Analysis of Wedge in Rock Slope Based on Kinetic Vector Method显示文摘A new method(kinetic vector method, KVM) is presented for analyzing the dynamic stability of wedge in rock slope. The dynamic analysis is carried out based on three dimensional distinct element code(3DEC), and the kinetic inertial force of the wedge under seismic loading can be obtained via calculating the net vectorial nodal force of the finite difference grid. Then, the factor of safety(FOS) of the wedge can be calculated based on limit equilibrium method(LEM) at each dynamic analysis step, therefore time series of the FOS for whole earthquake process can be obtained. For the purpose of evaluating the entire dynamic stability of the wedge, dynamic factor of safety(DFOS) is proposed and defined as a numerical value corresponding with a given rate of probability guarantee based on reliability theory. Consequently, the KVM inherits the merits of the LEM and also has fully nonlinear dynamic analysis capabilities, and the feasibility and correctness of the KVM are tested by an example given by Hoek and Bray(1981). Finally, a rock slope case in Wenchuan Earthquake regions of China is presented to verify the engineering practicability of the KVM, and the results matched the actual situation well. | Weida Ni Huiming Tang Xiao Liu Rui Yong Zongxing Zou | 2014 | Journal of Earth Science2014，25，4： | 4 |
| 5 | Wafer-scale arrayed p-n junctions based on few-layer epitaxial GaTe显示文摘二维(2D ) 材料吸引了实质的注意在电子并且有灵活、透明、高度悦耳的优异优点的 optoelectronic 应用。当时,无差距的 graphene 展出极端宽带、快的 photoresponse 半导体的瞬间 2 和门高展出的 2D 敏感和悦耳的 responsivity 到可见的光。然而,设备收益和重覆性打电话让进一步的改进完成大规模一致性。这里,我们与 28.4 厘米 2/(V0 的高洞活动性报导晶片规模门的 layer-by-layer | Xiang Yuan Lei Tang Peng Wang Zhigang Chen Yichao Zou Xiaofeng Su Cheng Zhang Yanwen Liu Weiyi Wang Cong Liu Fansheng Chen Jin Zou Peng Zhou Weida Hu Faxian Xiu | 2015 | Nano Research2015，8，10： | 4 |
| 6 | Tinea faciei in a newborn due toTrichophyton tonsurans显示文摘We report here the first case of neonatal tinea faciei caused by Trichophyton tonsurans in China's Mainland.The mother of the infant had tinea corpris and tinea capitis while the father had tinea incongnito.The infections in the parents were mycologically confirmed to be due to Trichophyton tonsurans.Ttinea faciei in the infant was cured after two-week topical use of amorolfine cream.The mother ceased breastfeeding and took oral terbinafine for 4 weeks.No recurrence was observed in the infant during 12 months of follow-up. | Meihua Fu Yiping Ge Wei Chen Suying Feng Xiaodong She Xiaofang Li Weida Liu | 2013 | The Journal of Biomedical Research2013，27，1： | 3 |
| 7 | Preparation of Ti-based Yb-doped SnO_(2)-RuO_(2) electrode and electrochemical oxidation treatment of coking wastewater显示文摘In this study,the Ti/SnO_(2)-RuO_(2) electrodes with different Yb contents were prepared by sol-gel method and thermal decomposition method,and the surface morphology and crystal structure of the electrodes were characterized by scanning electron microscopy(SEM),atomic force microscopy(AFM) and X-ray diffraction(XRD),the electrochemical properties of the electrodes were tested by linear sweep voltammetry(LSV) and cyclic voltammetry(CV).The electrochemical oxidation device was constructed with Yb-doped Ti/SnO_(2)-RuO_(2) electrode as the anode and titanium plate as the cathode,and the electrochemical oxidation effect and product changes of the anode on co king wastewater were investigated.The results show that the surface of the electrode is flat with high crystallinity of SnO_(2) and RuO_(2) crystals at1.5% Yb doping,and the LSV and CV curves indicate that the Yb doping of 1.5% increases the oxygen precipitation potential and electrocatalytic oxidation activity of the electrode.When the electrode with Yb doping of 1.5% is the anode with current density of 10 mA/cm^(2) electrochemical oxidation time of 30 min,the electrode can remove chemical oxygen demand(COD) up to 85.06%,total organic carbon(TOC) up to 60.59% and UV_(254) from 1.594 to 0.507 for coking wastewater.Gas chromatography(GC-MS),UV-vis and three-dimensional fluorescence results of coking wastewater before and after treatment show that large toxic substances in coking wastewater are degraded to low toxic organic substances,and most soluble organic substances are degraded and transformed.This study provides the possibility of basic research for the engineering practice of electrochemical oxidation for the treatment of coking wastewater. | Weida Wang Ke Wang Wenting Hao Tingting Zhang Yijie Liu Linghong Yu Weiping Li | 2022 | Journal of Rare Earths2022，40，5： | 2 |
| 8 | The association of grip strength with cardiovascular diseases and all-cause mortality in people with hypertension:Findings from the Prospective Urban Rural Epidemiology China Study显示文摘Background:Both hypertension and grip strength(GS)are predictors of mortality and cardiovascular disease(CVD),but whether these risk factors interact to affect CVD and all-cause mortality is unknown.This study sought to investigate the associations of GS with the risk of major CVD incidence,CVD mortality,and all-cause mortality in patients with hypertension.Methods:GS was measured using a Jamar dynamometer(Sammons Preston,Bolingbrook,IL,USA)in participants aged 3570 years from 12 provinces included in the Prospective Urban Rural Epidemiology China Study.Cox frailty proportional hazards models were used to examine the associations of GS and hypertension and the outcomes of all-cause mortality and CVD incidence/mortality.Results:Among 39,862 participants included in this study,15,964 reported having hypertension,and 9095 had high GS at baseline.After a median follow-up of 8.9 years(interquartile range,6.79.9 years),1822 participants developed major CVD,and 1250 deaths occurred(388 as a result of CVD).Compared with normotensive participants with high GS,hypertensive patients with high GS had a higher risk of major CVD incidence(hazard ratio(HR)=2.39;95%confidence interval(95%CI):1.863.06;p<0.001)or CVD mortality(HR=3.11;95%CI:1.596.06;p<0.001)but did not have a significantly increased risk of all-cause mortality(HR=1.24;95%CI:0.921.68;p=0.159).These risks were further increased if hypertensive participants whose GS level was low(major CVD incidence,HR=3.31,95%CI:2.604.22,p<0.001;CVD mortality,HR=4.99,95%CI:2.649.43,p<0.001;and all-cause mortality,HR=1.93,95%CI:1.472.53,p<0.001).Conclusion:The present study demonstrates that low GS is associated with the highest risk of major CVD incidence,CVD mortality,and all-cause mortality among hypertensive patients.High levels of GS appear to mitigate long-term mortality risk among hypertensive patients. | Weida Liu Darryl P Leong Bo Hu Lap AhTse Sumathy Rangarajan Yang Wang Chuangshi Wang Fanghong Lu Yindong Li Salim Yusuf Lisheng Liu Wei Li | 2021 | Journal of Sport and Health Science2021，10，6： | 2 |
| 9 | Stoichiometric effect on electrical and near-infrared photodetection properties of full-composition-range GaAs1−xSbx nanowires显示文摘As one of the most important narrow bandgap ternary semiconductors, GaAs1−xSbx nanowires (NWs) have attracted extensive attention recently, due to the superior hole mobility and the tunable bandgap, which covers the whole near-infrared (NIR) region, for technological applications in next-generation high-performance electronics and NIR photodetection. However, it is still a challenge to the synthesis of high-quality GaAs1−xSbx NWs across the entire range of composition, resulting in the lack of correlation investigation among stoichiometry, microstructure, electronics, and NIR photodetection. Here, we demonstrate the success growth of high-quality GaAs1−xSbx NWs with full composition range by adopting a simple and low-cost surfactant-assisted solid source chemical vapor deposition method. All of the as-prepared NWs are uniform, smooth, and straight, without any phase segregation in all stoichiometric compositions. The lattice constants of each NW composition have been well correlated with the chemical stoichiometry and confirmed by high-resolution transmission electron microscopy, X-ray diffraction, and Raman spectrum. Moreover, with the increase of Sb concentration, the hole mobility of the as-fabricated field-effect-transistors and the responsivity and detectivity of the as-fabricated NIR photodetectors increase accordingly. All the results suggest a careful stoichiometric design is required for achieving optimal NW device performances. | Jiamin Sun Mingming Han Meng Peng Lei Zhang Dong Liu Chengcheng Miao Jiafu Ye Zhiyong Pang Longbing He Hailu Wang Qing Li Peng Wang Lin Wang Xiaoshuang Chen Chongxin Shan Litao Sun Weida Hu Zai-xing Yang | 2021 | Nano Research2021，14，11： | 1 |
| 10 | Resveratrol ameliorates subacute intestinal ischemia-reperfusion injury显示文摘 | WenPeng Dong FanFan Li ZhiGuo Pan ShenXi Liu Hao Yu XianYue Wang ShengHui Bi WeiDa Zhang | 2013 | Journal of Surgical Research2013，，： | 1 |
| 11 | Karyotype Analysis of Cryptococcus Neoformans with Pulse Electrophoresis显示文摘 | Xiaodong She Weida Liu Shaoxi Wu Ningru Guo | 2006 | Journal of US-China Medical Science2006，3，2： | 1 |
| 12 | A path planning algorithm for autonomous flying vehicles in cross-countryenvironments with a novel TF-RRT^(*) method显示文摘Autonomous flying vehicles(AFVs)are promising future vehicles,which have high obstacle avoidance ability.To plan a feasible path in a wide range of cross-country environments for the AFV,a triggered forward optimal rapidly-exploring random tree(TF-RRT^(*))method is proposed.Firstly,an improved sampling and tree growth mechanism is built.Sampling and tree growth are allowed only in the forward region close to the target point,which significantly improves the planning speed;Secondly,the driving modes(ground-driving mode or air-driving mode)of the AFV are added to the sampling process as a planned state for uniform planning the driving path and driving mode;Thirdly,according to the dynamics and energy consumption models of the AFV,comprehensive indicators with energy consumption and efficiency are established for path optimal procedures,so as to select driving mode and plan driving path reasonably according to the demand.The proposed method is verified by simulations with an actual cross-country environment.Results show that the computation time is decreased by 71.08%compared with Informed-RRT^(*)algorithm,and the path length of the proposed method decreased by 13.01%compared with RRT^(*)-Connect algorithm. | Tianqi Qie Weida Wang Chao Yang Ying Li Wenjie Liu Changle Xiang | 2022 | Green Energy and Intelligent Transportation2022，1，3： | 1 |
| 13 | Development of knowledge-based system for adaptive scheduling using unified modeling language 显示文摘 | WANG Weida XU He LIU Wenjian | 2007 | WSEAS Transactions on Information Science and Applications2007，4，5： | 1 |
| 14 | Effect of TiO2/A1203 film coated diamond abrasive particles by sol-gel technique 显示文摘 | Weida Hu Long Wan Xiaopan Liu | 2011 | Applied Surface Science2011，，257： | 1 |
| 15 | A multi-objective power flow optimization control strategy for a power split plug-in hybrid electric vehicle using game theory显示文摘Power flow optimization control,which governs the energy flow among engine,battery,and motor,plays a very important role in plug-in hybrid electric vehicles(PHEVs).Its performance directly affects the fuel economy of PHEVs.For the purpose of improving fuel economy,the electric system including battery and motor will be frequently scheduled,which would affect battery life.Therefore,a multi-objective optimization mechanism taking fuel economy and battery life into account is necessary,which is also a research focus in field of hybrid vehicles.Motivated by this issue,this paper proposes a multi-objective power flow optimization control strategy for a power split PHEV using game theory.Firstly,since the demand power of driver which is necessary for the power flow optimization control,cannot be known in advance,the demand power of driver can be modelled using a Markov chain to obtain predicted demand power.Secondly,based on the predicted demand power,the multi-objective optimization control problem is transformed into a game problem.A novel non-cooperative game model between engine and battery is established,and the benefit function with fuel economy and battery life as the optimization objective is proposed.Thirdly,under the premise of satisfying various constraints,the participants of the above game maximize their own benefit function to obtain the Nash equilibrium,which comprises of optimal power split scheme.Finally,the proposed strategy is verified compared with two baseline strategies,and results show that the proposed strategy can reduce equivalent fuel consumption by about 15%compared with baseline strategy 1,and achieve similar fuel economy while greatly extend battery life simultaneously compared with baseline strategy 2. | WANG WeiDa WANG WeiQi YANG Chao LIU Cheng YANG LiuQuan SUN XiaoXia XIANG ChangLe | 2021 | Science China(Technological Sciences)2021，64，12： | 1 |
| 16 | Evaluation of a semi-quantitative ELISA for IgA antibody against Epstein–Barr virus capsid antigen in the serological diagnosis of nasopharyngeal carcinoma显示文摘 | Hao Chen Peidong Chi Weida Wang Linfang Li Yaoling Luo Jihuan Fu Liuyan Zhang Wanli Liu | 2014 | International Journal of Infectious Diseases2014，，： | 1 |
| 17 | Single-cell RNA Sequencing Reveals Sexually Dimorphic Transcriptome and Type 2 Diabetes Genes in Mouse Islet β Cells显示文摘Type 2 diabetes(T2D)is characterized by the malfunction of pancreaticβcells.Susceptibility and pathogenesis of T2D can be affected by multiple factors,including sex differences.However,the mechanisms underlying sex differences in T2D susceptibility and pathogenesis remain unclear.Using single-cell RNA sequencing(scRNA-seq),we demonstrate the presence of sexually dimorphic transcriptomes in mouseβcells.Using a high-fat diet-induced T2D mouse model,we identified sex-dependent T2D altered genes,suggesting sex-based differences in the pathological mechanisms of T2D.Furthermore,based on islet transplantation experiments,we found that compared to mice with sexmatched islet transplants,sex-mismatched islet transplants in healthy mice showed down-regulation of genes involved in the longevity regulating pathway ofβcells.Moreover,the diabetic mice with sex-mismatched islet transplants showed impaired glucose tolerance.These data suggest sexual dimorphism in T2D pathogenicity,indicating that sex should be considered when treating T2D.We hope that our findings could provide new insights for the development of precision medicine in T2D. | Gang Liu Yana Li Tengjiao Zhang Mushan Li Sheng Li Qing He Shuxin Liu Minglu Xu Tinghui Xiao Zhen Shao Weiyang Shi Weida Li | 2021 | Genomics, Proteomics & Bioinformatics2021，19，3： | 1 |
| 18 | Genetic variants in the Hedgehog signaling pathway genes are associated with gastric cancer risk in a Chinese Han population显示文摘The Hedgehog signaling pathway participates in the occurrence and progression of cancers including gastric cancer.We conducted this study to evaluate whether genetic variants in the Hedgehog signaling pathway genes would affect gastric cancer risk.Multi-marker Analysis of GenoMic Annotation(MAGMA)was used to investigate the aggregated genetic effects of single nucleotide polymorphisms(SNPs)assigned to candidate genes.The relationship between SNPs and gastric cancer risk was estimated by multivariate logistic regression analyses.Gene expression was calculated using databases obtained from The Cancer Genome Atlas(TCGA)and The Gene Expression Omnibus(GEO).Kaplan‐Meier plotter was used to evaluate the association between gene expression with gastric cancer survival.Tumor Immune Estimation Resource 2.0(TIMER 2.0)was applied to determine the correlation between selected gene expression and the immune cell infiltration degree.We identified that the G allele of rs2990912 in KIF27 was associated with higher gastric cancer risk,especially in the young and male subgroups.The expression of KIF27 in gastric cancer tissues was higher than that in normal tissues,leading to poor survival in gastric cancer patients.Besides,KIF27 expression was related to immune cell infiltration and positively correlated with PD-L1 expression.Our findings highlight the key role of genetic variation in the Hedgehog signaling pathway genes in gastric cancer susceptibility,which may provide important insights into the diagnosis,prognosis,and treatment of gastric cancer. | Yujuan Zhang Kai Lu Xu Wu Hanting Liu Junyi Xin Xiaowei Wang Weida Gong Qinghong Zhao Meilin Wang Haiyan Chu Mulong Du Guoquan Tao Zhengdong Zhang | 2022 | The Journal of Biomedical Research2022，36，1： | 1 |
| 19 | Macroscopic assembled graphene nanofilms based room temperature ultrafast mid-infrared photodetectors显示文摘Graphene with linear energy dispersion and weak electron-phonon interaction is highly anticipated to harvest hot electrons in a broad wavelength range.However,the limited absorption and serious backscattering of hot-electrons result in inadequate quantum yields,especially in the mid-infrared range.Here,we report a macroscopic assembled graphene(nMAG)nanofilm/silicon heterojunction for ultrafast mid-infrared photodetection.The assembled Schottky diode works in 1.5-4.0μm at room temperature with fast response(20-30 ns,rising time,4 mm2 window)and high detectivity(1.61011 to 1.9109 Jones from 1.5 to 4.0μm)under the pulsed laser,outperforming single-layer-graphene/silicon photodetectors by 2-8 orders.These performances are attributed to the greatly enhanced photo-thermionic effect of electrons in nMAG due to its high light absorption(~40%),long carrier relaxation time(~20 ps),low work function(4.52 eV),and suppressed carrier number fluctuation.The nMAG provides a long-range platform to understand the hot-carrier dynamics in bulk 2D materials,leading to broadband and ultrafast MIR active imaging devices at room temperature. | Li Peng Lixiang Liu Sichao Du Srikrishna Chanakya Bodepudi Lingfei Li Wei Liu Runchen Lai Xiaoxue Cao Wenzhang Fang Yingjun Liu Xinyu Liu Jianhang Lv Muhammad Abid Junxue Liu Shengye Jin Kaifeng Wu Miao-Ling Lin Xin Cong Ping-Heng Tan Haiming Zhu Qihua Xiong Xiaomu Wang Weida Hu Xiangfeng Duan Bin Yu Zhen Xu Yang Xu Chao Gao | 2022 | InfoMat2022，4，6： | 1 |
| 20 | Topology Optimization of Metamaterial Microstructures for Negative Poisson’s Ratio under Large Deformation Using a Gradient-Free Method显示文摘Negative Poisson’s ratio(NPR)metamaterials are attractive for their unique mechanical behaviors and potential applications in deformation control and energy absorption.However,when subjected to significant stretching,NPR metamaterials designed under small strain assumption may experience a rapid degradation in NPR performance.To address this issue,this study aims to design metamaterials maintaining a targeted NPR under large deformation by taking advantage of the geometry nonlinearity mechanism.A representative periodic unit cell is modeled considering geometry nonlinearity,and its topology is designed using a gradient-free method.The unit cell microstructural topologies are described with the material-field series-expansion(MFSE)method.The MFSE method assumes spatial correlation of the material distribution,which greatly reduces the number of required design variables.To conveniently design metamaterials with desired NPR under large deformation,we propose a two-stage gradient-free metamaterial topology optimization method,which fully takes advantage of the dimension reduction benefits of the MFSE method and the Kriging surrogate model technique.Initially,we use homogenization to find a preliminary NPR design under a small deformation assumption.In the second stage,we begin with this preliminary design and minimize deviations in NPR from a targeted value under large deformation.Using this strategy and solution technique,we successfully obtain a group of NPR metamaterials that can sustain different desired NPRs in the range of[−0.8,−0.1]under uniaxial stretching up to 20% strain.Furthermore,typical microstructure designs are fabricated and tested through experiments.The experimental results show good consistency with our numerical results,demonstrating the effectiveness of the present gradientfree NPR metamaterial design strategy. | Weida Wu Yiqiang Wang Zhonghao Gao Pai Liu | 2024 | Computer Modeling in Engineering & Sciences2024，139，5： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员