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| 1 | XRCC1 and DNA polymerase β in cellular protection against cytotoxic DNA single-strand breaks显示文摘 | Julie K Horton Mary Watson Donna F Stefanick Daniel T Shaughnessy Jack A Taylor Samuel H Wilson | 2008 | Cell Research2008,18,1: | 17 |
| 2 | Rotational assisted endoscopic retrograde cholangiopancreatography in patients with reconstructive gastrointestinal surgical anatomy显示文摘AIM: To evaluate the success rates of performing therapy utilizing a rotational assisted enteroscopy device in endoscopic retrograde cholangiopancreatography(ERCP) in surgically altered anatomy patients. METHODS: Between June 1, 2009 and November 8, 2012, we performed 42 ERCPs with the use of rotational enteroscopy for patients with altered anatomy(39 with gastric bypass Roux-en-Y, 2 with Billroth Ⅱ gastrectomy, and 1 with hepaticojejunostomy associated with liver transplant). The indications for ERCP were: choledocholithiasis: 13 of 42(30.9%), biliary obstruction suggested on imaging: 20 of 42(47.6%), suspected sphincter of Oddi dysfunction: 4 of 42(9.5%), abnormal liver enzymes: 1 of 42(2.4%), ascending cholangitis: 2 of 42(4.8%), and bile leak: 2 of 42(4.8%). All procedures were completed with the Olympus SIF-Q180 enteroscope and the Endo-Ease Discovery SB overtube produced by Spirus Medical. RESULTS: Successful visualization of the major ampulla was accomplished in 32 of 42 procedures(76.2%). Cannulation of the bile duct was successful in 26 of 32 procedures reaching the major ampulla(81.3%). Successful therapeutic intervention was completed in 24 of 26 procedures in which the bileduct was cannulated(92.3%). The overall intention to treat success rate was 64.3%. In terms of cannulation success, the intention to treat success rate was 61.5%. Ten out of forty two patients(23.8%) required admission to the hospital after procedure for abdominal pain and nausea, and 3 of those 10 patients(7.1%) had a diagnosis of post-ERCP pancreatitis. The average hospital stay was 3 d.CONCLUSION: It is reasonable to consider an attempt at rotational assisted ERCP prior to a surgical intervention to alleviate biliary complications in patients with altered surgical anatomy. | Majed El Zouhairi James B Watson Svetang V Desai David K Swartz Alejandra Castillo-Roth Mahfuzul Haque Paul S Jowell Malcolm S Branch Rebecca A Burbridge | 2015 | World Journal of Gastrointestinal Endoscopy2015,7,3: | 10 |
| 3 | 健康领域的文化能力显示文摘1背景
尽管人类对其他社会的兴趣纵贯历史的各个阶段,但是检验不同文化概念对人类健康实践的影响从20世纪才开始,当时是伴随着长期的人类学田野调查产生的,这些田野调查揭露了不同文化之间相关卫生实践的多样性、复杂性和连续性。 | Napier A D Ancarno C Butler B Calabrese j Chater A Chatterjee H Guesnet F Home R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams AC Willott C Wilson J Woolf K | 2016 | 中国卫生政策研究2016,9,2: | 5 |
| 4 | Risk of colon cancer in hereditary non-polyposis colorectal cancer patients as predicted by fuzzy modeling:Influence of smoking显示文摘瞄准:为了调查一个模糊逻辑模型是否能预言肤色,表面的癌症(CRC ) 风险由在世袭 non-polyposis 肤色吸表面的癌症(HNPCC ) 病人产生了。方法:从 Creighton 大学世袭癌症研究所登记的 340 个 HNPCC 失配修理(MMR ) 变化搬运人为当模特儿被选择。年龄依赖者曲线被产生阐明开发 CRC 的概率上的在基因变化(hMLH1 或 hMSH2 ) 之间的联合效果,性,和吸烟地位。结果:在男 hMSH2 变化搬运人的吸烟显著地增加的 CRC 风险(P <
0.05 ) 。hMLH1 变化为男性相对 hMSH2 变化搬运人扩充了 CRC 风险(P <
0.05 ) 。男性们非为 hMLH1 比女性有 CRC 的显著地更高的风险吸烟者(P <
0.05 ) , hMLH1 吸烟者(P <
0.1 ) 并且 hMSH2 吸烟者(P <
0.1 ) 。以在在男性的 hMSH2 的一种剂量依赖者方式的吸烟支持的 CRC (P <
0.05 ) 。有 hMSH2 变化的女性和与 hMLH1 组一起的两性仅仅在广泛的吸烟历史以后表明了吸烟效果(P <
0.05 ) 。结论:由在 HNPCC 病人吸烟的 CRC 提升依赖于基因变化,性和年龄。这些数据证明模糊建模可以启用临床的风险分数的明确的表达,从而允许 CRC 预防策略的 individualization。 | Rhonda M Brand David D Jones Henry T Lynch Randall E Brand Patrice Watson Ramesh Ashwathnayaran Hemant K Roy | 2006 | World Journal of Gastroenterology2006,12,28: | 5 |
| 5 | Induction of angiogenesis during the transition from hyperplasia to neoplasia显示文摘 | Folkman J Watson K Ingber D | 1989 | Nature1989,339,6219: | 2 |
| 6 | 文化、不平等性与卫生服务提供显示文摘1动态不平等性对基层医疗卫生人力的影响
政治、社会、文化、专业群体皆建立在一致且常规的人类行为之上。当遭受巨大变革和内外压力时,这些群体会变得十分脆弱。尤其在动荡时期,这些群体往往更关注社会和文化的差异性,而非二者的一致性。尽管社会中的个体思维和行为会呈现较大的差异,但对健康的感知具有统一性,并在更广范围人群内尤为突出,这主要归因于文化价值观的作用。广义的文化心态会随着时间和地理位置的不同而不同,就像健康的社会决定因素也会因文化类型的不同而产生差异。 | Napier A D Ancarno C Butler B Calabrese J Chater A Chatterjee H Guesnet F Horne R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams A C Willott C Wilson J Woolf K | 2016 | 中国卫生政策研究2016,9,3: | 2 |
| 7 | Induction of angiogenesis during the transition from hyperplasia to neoplasia显示文摘 | Folkman J Watson K Ingber D | 1989 | Nature1989,339,6219: | 2 |
| 8 | A tiling resolution DNA microarray with complete coverage of the human genome显示文摘 | Ishkanian A S Malloff C A Watson S K | 2004 | Nat Genet2004,36,3: | 1 |
| 9 | HIV-1-trans-activating (Tat) protein:both a target and a tool in therapeutic approaches显示文摘 | Watson K Edwards R J | 1999 | Biochem Pharmacol (Review)1999,58,10: | 1 |
| 10 | Prognostic significance of a novel hypoxia-regulated marker,carbonic anhydrase IX,in invasive breast carcinoma显示文摘 | Chia S K Wykoff C C Watson P H | 2001 | J Clin Oncol2001,19,16: | 1 |
| 11 | An instantaneous profile method for determining the hydraulic conductivity of un saturated porous material 显示文摘 | WATSON K K | 1966 | Water Resources Research1966,2,: | 1 |
| 12 | Macrophage inflammatory protein 2 inhib-its beta-amyloid peptide(1-42)-mediated hippocampal neuronalapoptosis through activation of mitogen-activated protein kinaseand phosphatidylinositol 3-kinase signaling pathways显示文摘 | Watson K Fan G H | 2005 | MolPharmacol2005,67,3: | 1 |
| 13 | Estimating macroporosity ina forest watershed by use of a tension infiltrometer 显示文摘 | Watson K W Luxmoore R J | 1986 | Soil Science Society of America Journal1986,50,3: | 1 |
| 14 | Identification of dehydration-responsive cysteine proteases during post-harvest senescence of broccoli florets显示文摘 | Coupe A S Sinclair B K Watson B K | 2003 | Journal of Experimental Botany2003,54,384: | 1 |
| 15 | Self-organizing hierarchical particle swarm optimizer with time-varying acceleration coefficients 显示文摘 | RATNAWEERA A HALGAMUGE S K WATSON H C | 2004 | Transactions on Evolutionary Computation2004,8,3: | 1 |
| 16 | Mechanism of electrode surface damage and material removal in high current discharges显示文摘 | Watson A Donaldson A Ikuta K | | 0,,06: | 1 |
| 17 | Variant Cizl is a circu- lating biomarker for early-stage lung cancer 显示文摘 | Higgins G Roper K M Watson I J | 2012 | PNAS2012,109,45: | 1 |
| 18 | An adaptive Kalman filter for dynamic harmonic state estimation and harmonic injection tracking显示文摘 | Yu K K C Watson N R Arrillaga J | 2005 | IEEE Transactions on Power Delivery2005,20,2: | 1 |
| 19 | Increased serum concentration of sphingosine-1-phosphate in juvenile-onset systemic lupus erythematosus显示文摘 | Watson L Tullus K Marks S D | 2012 | J Clin Immunol2012,32,5: | 1 |
| 20 | Tightrope act: autophagy in stem cell renewal, differentiation, proliferation, and aging 显示文摘 | Phadwal K Watson AS Simon AK | 2013 | Cell Mol Life Sci2013,70,1: | 1 |