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| 1 | 组织工程化人工神经修复长段神经缺损实验的初步报告显示文摘目的 研究组织工程化人工神经修复大鼠 2 .5cm长坐骨神经缺损的效果。方法 90只 2个月月龄的Lewis 1W雌性大鼠 ,按手术先后顺序随机分成 3个神经移植组 ,每组 3 0只。A组 :用种植同源雪旺细胞并具有内部支架结构的胶原神经管桥接 ,即组织工程化人工神经组。B组 :用无雪旺细胞但具有内部支架结构的胶原神经管桥接 ,即对照组。C组 :自体神经移植组。术后 6个月 ,进行神经电生理监测 ,神经肌肉组织学观察 ;用S 10 0和神经微丝蛋白免疫组化染色后 ,行轴突计数等检测。结果 完成对 2 1只大鼠 (每组 7只 )的实验评估。从A组和C组的胫前肌中均能诱发出波幅明显的神经肌肉复合动作电位 (CMAP) ,再生轴突已通过移植段神经全长 ,远端肌肉轻度萎缩。B组中则没有或仅记录到波幅很低的CMAP ,移植神经远端结缔纤维组织增生 ,再生轴突罕见 ,所支配肌肉明显萎缩。结论 组织工程化人工神经可用来修复大鼠长段神经缺损。 | 沈尊理 Berger Alfred Hierner Robert Lohmeyer Joern Allmeling Christina Walter F.Gerhard | 2001 | 中华手外科杂志2001,17,2: | 22 |
| 2 | Activins and activin antagonists in hepatocellular carcinoma显示文摘In many parts of the world hepatocellular carcinoma (HCC)is among the leading causes of cancer-related mortality but the underlying molecular pathology is still insufficiently understood.There is increasing evidence that activins,which are members of the transforming growth factorβ(TGFβ)superfamily of growth and differentiation factors,could play important roles in liver carcinogenesis.Activins are disulphide-linked homo- or heterodimers formed from four differentβsubunits termedβA,βB,βC,andβE,respectively.Activin A, the dimer of twoβA subunits,is critically involved in the regulation of cell growth,apoptosis,and tissue architecture in the liver,while the hepatic function of other activins is largely unexplored so far.Negative regulators of activin signals include antagonists in the extracellular space like the binding proteins follistatin and FLRG,and at the cell membrane antagonistic coreceptors like Cripto or BAMBI.Additionally,in the intracellular space inhibitory Smads can modulate and control activin activity.Accumulating data suggest that deregulation of activin signals contributes to pathologic conditions such as chronic inflammation,fibrosis and development of cancer.The current article reviews the alterations in components of the activin signaling pathway that have been observed in HCC and discusses their potential significance for liver tumorigenesis. | Alev Deli Emanuel Kreidl Stefan Santifaller Barbara Trotter Katja Seir Walter Berger Rolf Schulte-Hermann Chantal Rodgarkia-Dara Michael Grusch | 2008 | World Journal of Gastroenterology2008,14,11: | 8 |
| 3 | 组织工程化人工神经实验研究显示文摘目的 研究组织工程化人工神经修复大鼠2.5cm长坐骨神经缺损的效果。方法 21只2月龄Lewis lw雌性大鼠随机分成三个神经移植组,每组7只。A组:种植同源雪旺细胞并具有内部支架结构的胶原神经管,即组织工程化人工神经。B组:无雪旺细胞但具有内部支架结构的胶原神经管。C组:自体神经移植组。术后六个月,进行系列神经电生理监测,神经肌肉组织学观察,S-100和神经微丝蛋白(Neurofilament)免疫组化染色,轴突计数等检查。结果 在A组和C组移植神经上均能诱发出波幅明显的神经肌肉复合动作电位(CMAP),再生轴突已通过移植神经全长,远端肌肉轻度萎缩。而B组中没有或仅记录到极小波幅的CMAP,移植神经远端结缔纤维组织增生,再生轴突罕见,所支配肌肉明显萎缩。结论 初步结果显示:组织工程化人工神经可用来修复大鼠长段神经缺损。 | 沈尊理 BERGER Alfred HIERNER Robert LOHMEYER Joern ALLMELING Christina WALTER F.Gerhard | 2000 | 中国创伤骨科杂志2000,2,4: | 4 |
| 4 | 针刺推拿结合治疗Sudeck骨萎缩46例临床观察显示文摘目的:观察针刺推拿结合治疗Sudeck骨萎缩的临床疗效。方法:将92例Sudeck骨萎缩患者随机分为治疗组和对照组各46例,治疗组采用针刺加推拿手法,对照组采用单纯针刺法,以临床疗效、评定疼痛的视觉模拟评分(visual analogue scale VAS)及腕关节功能Dienst分级评分为观察指标。结果:两组均取得明显的疗效,且治疗组明显优于对照组(P<0.01);与对照组相比,VAS评分(cm,2.01±2.03 vs 3.16±2.22)及Dienst评分(优21 vs 11例;良15 vs 12例;可6 vs 14例;差4 vs 9例)均有显著性差异(P<0.01)。结论:针刺、推拿疗法治疗Sudeck骨萎缩疗效确切,针刺推拿结合法的疗效明显优于单纯针刺法,尤其在消肿止痛、改善腕关节功能方面具有显著的优势,值得推广应用。 | 熊学琼 毕旭伟 Walter Joanlin Susanne Berger | 2013 | 四川中医2013,31,3: | 2 |
| 5 | Impact of CYP24A1 overexpression on growth of colorectal tumour xenografts in mice fed with vitamin D and soy显示文摘 | Julia H?baus Samawansha Tennakoon Petra Heffeter Charlotte Groeschel Abhishek Aggarwal Doris M. Hummel Ursula Thiem Rodrig Marculescu Walter Berger Enik? Kállay | 2016 | Int. J. Cancer2016,,2: | 1 |
| 6 | Hyponatremia in a pediatric stroke patient: Syndrome of inappro- priate antidiuretie hormone secretion or cerebral salt wasting? 显示文摘 | Berger Thomas MMD Kistler Walter MD Berendes Elmar MD | 2002 | Critical Care Medicine2002,30,: | 1 |
| 7 | A comparative study of unsedated transnasal esophagogastroduodenoscopy and conventional EGD显示文摘 | Robert Dean Kulwinder Dua Benson Massey William Berger Walter J. Hogan Reza Shaker | 1996 | Gastrointestinal Endoscopy1996,,4: | 1 |
| 8 | Interaction between fatty acid synthase- and ErbB-systems in ovarian cancer cells显示文摘 | Thomas W. Grunt Renate Wagner Michael Grusch Walter Berger Christian F. Singer Brigitte Marian Christoph C. Zielinski Ruth Lupu | 2009 | Biochemical and Biophysical Research Communications2009,,3: | 1 |
| 9 | Downregulation of TSLC1 and DAL-1 expression occurs frequently in breast cancer显示文摘 | Gerwin Heller Joseph Geradts Barbara Ziegler Irene Newsham Martin Filipits Eva-Maria Markis-Ritzinger Daniela Kandioler Walter Berger Wolfgang Stiglbauer Dieter Depisch Robert Pirker Christoph C. Zielinski Sabine Z?chbauer-Müller | 2007 | Breast Cancer Research and Treatment2007,,: | 1 |
| 10 | Hydrogen peroxide mediates EGCG-induced antioxidant protection in human keratinocytes显示文摘 | Leonilla Elbling Irene Herbacek Rosa-Maria Weiss Christian Jantschitsch Michael Micksche Christopher Gerner Heinrich Pangratz Michael Grusch Siegfried Knasmüller Walter Berger | 2010 | Free Radical Biology and Medicine2010,,9: | 1 |
| 11 | Combined Targeted Treatment to Eliminate Tumorigenic Cancer Stem Cells in Human Pancreatic Cancer显示文摘 | Maria–Theresa Mueller Patrick C. Hermann Juliane Witthauer Belen Rubio–Viqueira Simon F. Leicht Stephan Huber Joachim W. Ellwart Mona Mustafa Peter Bartenstein Jan G. D’Haese Michael H. Schoenberg Frank Berger Karl–Walter Jauch Manuel Hidalgo Christopher | 2009 | Gastroenterology2009,,: | 1 |
| 12 | Development of a Clinical Score (A2DS2) to Predict Pneumonia in Acute Ischemic Stroke显示文摘 | Sarah Hoffmann Uwe Malzahn Hendrik Harms Hans-Christian Koennecke Klaus Berger Marianne Kalic Georg Walter Andreas Meisel Peter Ulrich Heuschmann | 2012 | Stroke2012,,10: | 1 |
| 13 | Temporal Repolarization Lability in Hypertrophic Cardiomyopathy Caused by β-Myosin Heavy-Chain Gene Mutations显示文摘 | Walter L. Atiga Lameh Fananapazir Dorothea McAreavey Hugh Calkins Ronald D. Berger | 2000 | Circulation: Journal of the American Heart Association2000,,: | 1 |
| 14 | Trabectedin has promising antineoplastic activity in high‐grade meningioma显示文摘 | Matthias Preusser Sabine Spiegl‐Kreinecker Daniela L?tsch Adelheid W?hrer Maria Schmook Karin Dieckmann Walter Saringer Christine Marosi Walter Berger | 2012 | Cancer2012,,20: | 1 |
| 15 | Multidrug resistance markers P-glycoprotein, multidrug resistance protein 1, and lung resistance protein in non-small cell lung cancer: prognostic implications显示文摘 | Walter Berger Ulrike Setinek Peter Hollaus Thomas Zidek Elisabeth Steiner L. Elbling H. Cantonati Johannes Attems Andrea Gsur Michael Micksche | 2005 | Journal of Cancer Research and Clinical Oncology2005,,6: | 1 |
| 16 | Multidrug resistance markers P - glycoprotein, multidrug resistance protein 1, and lung resistance protein in non - small cell lung cancer: prognostic implications显示文摘 | Walter Berger Ulrike Setinek Peter Hollaus | 2005 | Cancer2005,131,: | 1 |
| 17 | Combined Targeted Treatment to Eliminate Tumorigenic Cancer Stem Cells in Human Pancreatic Cancer显示文摘 | Maria–Theresa Mueller Patrick C. Hermann Juliane Witthauer Belen Rubio–Viqueira Simon F. Leicht Stephan Huber Joachim W. Ellwart Mona Mustafa Peter Bartenstein Jan G. D’Haese Michael H. Schoenberg Frank Berger Karl–Walter Jauch Manuel Hidalgo Christopher | 2009 | Gastroenterology2009,,3: | 1 |
| 18 | Use of poly(styrene)-block-poly(ethyleneoxide) as emulsifier in emulsion polymerization显示文摘 | Markus Berger Walter Richtering Rolf Mülhaupt | 1994 | Polymer Bulletin1994,,5: | 1 |
| 19 | Biventricular repair in children with complete atrioventricular septal defect and a small left ventricle显示文摘 | Eva Maria Delmo Walter Peter Ewert Roland Hetzer Michael Hübler Vladimir Alexi-Meskishvili Peter Lange Felix Berger | 2008 | European Journal of Cardio-Thoracic Surgery2008,,1: | 1 |
| 20 | Downregulation of TSLC1 and DAL-1 expression occurs frequently in breast cancer显示文摘 | Gerwin Heller Joseph Geradts Barbara Ziegler Irene Newsham Martin Filipits Eva-Maria Markis-Ritzinger Daniela Kandioler Walter Berger Wolfgang Stiglbauer Dieter Depisch Robert Pirker Christoph C. Zielinski Sabine Z?chbauer-Müller | 2007 | Breast Cancer Research and Treatment2007,,3: | 1 |