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| 1 | Ship detection and classification from optical remote sensing images: A survey显示文摘Considering the important applications in the military and the civilian domain, ship detection and classification based on optical remote sensing images raise considerable attention in the sea surface remote sensing filed. This article collects the methods of ship detection and classification for practically testing in optical remote sensing images, and provides their corresponding feature extraction strategies and statistical data. Basic feature extraction strategies and algorithms are analyzed associated with their performance and application in ship detection and classification.Furthermore, publicly available datasets that can be applied as the benchmarks to verify the effectiveness and the objectiveness of ship detection and classification methods are summarized in this paper. Based on the analysis, the remaining problems and future development trends are provided for ship detection and classification methods based on optical remote sensing images. | Bo LI Xiaoyang XIE Xingxing WEI Wenting TANG | 2021 | Chinese Journal of Aeronautics2021，34，3： | 7 |
| 2 | C:N:P stoichiometry of Ericaceae species in shrubland biomes across Southern China:influences of climate,soil and species identity显示文摘Aims Carbon(C),nitrogen(N)and phosphorus(P)stoichiometry strongly affect functions and nutrient cycling within ecosystems.However,the related researches in shrubs were very limited.In this study,we aimed to inves-tigate leaf stoichiometry and its driving factors in shrubs,and whether stoichiometry significantly differs among closely related species.Methods We analyzed leaf C,N and P concentrations and their ratios in 32 species of Ericaceae from 161 sites across southern China.We examined the relationships of leaf stoichiometry with environmen-tal variables using linear regressions,and quantified the interactive and independent effects of climate,soil and species on foliar stoi-chiometry using general linear models(GLM).Important Findings The foliar C,N and P contents of Ericaceae were 484.66,14.44 and 1.06 mg g−1,respectively.Leaf C,N and P concentrations and their ratios in Ericaceae were significantly related with latitude and altitude,except the N:P insignificantly correlated with latitude.Climate(mean annual temperature and precipitation)and soil properties(soil C,N and P and bulk density)were significantly influenced element stoichiom-etry.The GLM analysis showed that soil exerted a greater direct effect on leaf stoichiometry than climate did,and climate affected leaf traits mainly via indirect ways.Further,soil properties had stronger influ-ences on leaf P than on leaf C and N.Among all independent factors examined,we found species accounted for the largest proportion of the variation in foliar stoichiometry.These results suggest that species can largely influence foliar stoichiometry,even at a lower taxonomic level. | Qiang Zhang Qing Liu Huajun Yin Chunzhang Zhao Lin Zhang Guoying Zhou Chunying Yin Zhijun Lu Gaoming Xiong Yuelin Li Jiaxiang Li Wenting Xu Zhiyao Tang Zongqiang Xie | 2019 | Journal of Plant Ecology2019，12，2： | 4 |
| 3 | Dendrocalamus latiflorus and its component rutin exhibit glucose-lowering activities by inhibiting hepatic glucose production via AKT activation显示文摘The potential medicinal value of Ma bamboo(Dendrocalamus latiflorus), one of the most popular and economically important bamboo species in China, has been underestimated. In the present study, we found that D. latiflorus leaf extract(DLE) reduced fasting blood glucose levels, body weight,and low-density lipoprotein cholesterol with low liver toxicity in db/db mice. In addition, gene expression profiling was performed and pathway enrichment analysis showed that DLE affected metabolic pathways.Importantly, DLE activated the AKT signaling pathway and reduced glucose production by downregulating glucose-6-phosphatase(G6 PC) and phosphoenolpyruvate carboxykinase 1(PCK1) expression. Moreover, network pharmacology analysis identified rutin as an active component in DLE through targeting insulin growth factor 1 receptor(IGF1 R), an upstream signaling transducer of AKT. Due to its hypoglycemic effects and low toxicity, DLE may be considered an adjuvant treatment option for type 2 diabetes patients. | Kun Luo Wenting Huang Liansheng Qiao Xiaoling Zhang Di Yan Zhiyu Ning Chengmei Ma Honglei Dang Dong Wang Hongyan Guo Lan Xie Jing Cheng | 2022 | Acta Pharmaceutica Sinica B2022，12，5： | 4 |
| 4 | Evaluation of the immunomodulatory effects of anti-COVID-19 TCM formulae by multiple virus-related pathways显示文摘Dear Editor,The coronavirus infectious disease 2019(COVID-19)outbreak is seriously endangering human health.Most patients with severe COVID-19 are characterized by sustained cytokine production and hyper-inflammation,which is known as cytokine storm syndrome.1-3 Elaborating the anti-inflammatory response is crucial to these patients,and interieukin-6(IL6)inhibitors and steroids have been recommended in clinical practice.1 However,after the cytokine storm phase,the host immune response to sepsis may develop into a protracted immunosuppressive phase. | Liansheng Qiao Wenting Huang Xiaoling Zhang Hongyan Guo Dong Wang Quansheng Feng Ronghua Jin Lan Xie Weimin Li Jing Cheng | 2021 | Signal Transduction and Targeted Therapy2021，6，3： | 4 |
| 5 | General synthesis of high-performing magneto-conjugated polymer core-shell nanoparticles for multifunctional theranostics显示文摘最近,增加注意作为 theranostic 平台被付了到结合磁电机的聚合物核心壳 nanoparticles (NP ) 。然而,表面活化剂的利用和有在合成的潜在的毒性的额外的氧化剂,为磁性的 NP ( MNP )@的各种各样的类型的控制合成的一般方法的缺乏结合了聚合物 NP ,并且获得平衡磁电机光的性质的困难极大地在 theranostics 限制了结合磁电机的聚合物的应用。我们发展了一在里面没有额外的表面活化剂和氧化剂的 situ 表面聚合方法综合有平衡、突出的磁电机光的性质的 MNP@polypyrrole (PPy ) NP。有一种可调节的尺寸,不同形状,和控制的壳厚度的 MNP@PPy NP 用这个方法被获得。方法被扩大综合另外的结合 MNP 的聚合物核心壳 NP,例如 MNP@polyaniline 并且 MNP@poly (3,4-ethylenedioxythiophene ): poly (4-styrenesulfonate )(PEDOT : PSS ) 。我们根据我们的试验性的结果讨论建议方法的形成机制。最后,使用光并且获得的 MNP@PEDOT 的磁性: PSS NP,在 vivo,多模式的指导成像的过高热在老鼠被导致,完成优秀肿瘤脱离治疗学的效果。我们的工作为在生物医学的域里扩大结合 MNP 的聚合物核心壳 NP 的应用程序是有益的。 | Hao Yan Lingyun Zhao Wenting Shang Zhongqun Liu Wensheng Xie Cai Qiang Zhiyuan Xiong Ranran Zhang Baohua Li Xiaodan Sun Feiyu Kang | 2017 | Nano Research2017，10，2： | 2 |
| 6 | Lycium barbarum polysaccharides ameliorate canine acute liver injury by reducing oxidative stress,protecting mitochondrial function,and regulating metabolic pathways显示文摘The development of acute liver injury can result in liver cirrhosis,liver failure,and even liver cancer,yet there is currently no effective therapy for it.The purpose of this study was to investigate the protective effect and therapeutic mechanism of Lycium barbarum polysaccharides(LBPs)on acute liver injury induced by carbon tetrachloride(CCl_(4)).To create a model of acute liver injury,experimental canines received an intraperitoneal injection of 1 mL/kg of CCl_(4)solution.The experimental canines in the therapy group were then fed LBPs(20 mg/kg).CCl_(4)-induced liver structural damage,excessive fibrosis,and reduced mitochondrial density were all improved by LBPs,according to microstructure data.By suppressing Kelch-like epichlorohydrin(ECH)-associated protein 1(Keap1),promoting the production of sequestosome 1(SQSTM1)/p62,nuclear factor erythroid 2-related factor 2(Nrf2),and phaseⅡdetoxification genes and proteins downstream of Nrf2,and restoring the activity of anti-oxidant enzymes like catalase(CAT),LBPs can restore and increase the antioxidant capacity of liver.To lessen mitochondrial damage,LBPs can also enhance mitochondrial respiration,raise tissue adenosine triphosphate(ATP)levels,and reactivate the respiratory chain complexes I–V.According to serum metabolomics,the therapeutic impact of LBPs on acute liver damage is accomplished mostly by controlling the pathways to lipid metabolism.9-Hydroxyoctadecadienoic acid(9-HODE),lysophosphatidylcholine(Lyso PC/LPC),and phosphatidylethanolamine(PE)may be potential indicators of acute liver injury.This study confirmed that LBPs,an effective hepatoprotective drug,may cure acute liver injury by lowering oxidative stress,repairing mitochondrial damage,and regulating metabolic pathways. | JIANJIA HUANG YUMAN BAI WENTING XIE RONGMEI WANG WENYUE QIU SHUILIAN ZHOU ZHAOXIN TANG JIANZHAO LIAO RONGSHENG SU | 2023 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2023，24，2： | 2 |
| 7 | Long-term trends of precipitation and erosivity over Northeast China during 1961-2020显示文摘Northeast China(NEC)is one of the vital commercial grain bases in China and it has suffered from soil erosion due to prolonged cultivation and lack of protection.To determine long-term trends of precipi-tation and rainfall erosivity over NEC during the latest decades,daily precipitation for the entire year during 1961-2020 and hourly precipitation for the warm season(May to September)during 1971-2020 were collected for 192 and 126 stations,respectively.Three seasons,including the cold season(October to April),early warm season(May to June),and late warm season(July to September)were divided according to the combination of precipitation and vegetation.Results demonstrate:(1)Daily precipita-tion reveals total precipitation and rainfall erosivity in the cold season and early warm season increase significantly at relative rates of 3.1%-6.1%compared with the average during 1961-2020,and those in the late warm season decrease insignificantly.(2)Hourly precipitation reveals storms occurring in the early and late warm seasons have undergone significant increasing changes,which shift towards longer storm duration,larger amount,peak intensity,kinetic energy,and rainfall erosivity during 1971-2020.Moreover,the frequency of extreme storms increased.(3)Rainfall erosivities estimated from daily pre-cipitation during 1971-2020 increase insignificantly for the early and late warm season,whereas those from hourly precipitation increase significantly(6.1%and 5.5%,respectively),which indicates daily precipitation may not be able to capture the trend fully under the warming background,and precipi-tation at higher resolutions than the daily scale is necessary to detect trends of rainfall erosivity more accurately. | Wenting Wang Shuiqing Yin Juan Yu Zeng He Yun Xie | 2023 | International Soil and Water Conservation Research2023，11，4： | 2 |
| 8 | Genome and Comparative Transcriptomics of African Wild Rice Oryza Iongistaminata Provide Insights into Molecular Mechanism of Rhizomatousness and Self-Incompatibility显示文摘Dear Editor, Oryza Iongistaminata is an African wild rice species with AA genome type possessing special traits that are highly valued for improving cultivated rice,such as strong resistance to biotic and abiotic stresses (Song et al.,1995) for improving resistance of cultivars,rhizomatousness for perennial breeding (Glover et al.,2010),and self-incompatibility (SI) for new ways to produce hybrid seeds (Ghesquiere,1986).Deciphering the genome of O.longistaminata will be the key to uncovering the mechanism of these hallmark traits and improving cultivated rice. | Yesheng Zhang Shilai Zhang Hui Liu Binying Fu Lijuan Li Min Xie Yue Song Xin Li Jing Cai Wenting Wan Ling Kui Hui Huang Jun Lyu Yang Dong Wensheng Wang Liyu Fluang Jing Zhang Qinzhong Yang Qinfi Shan Qiong Li Wangqi Huang Dayun Tao Muhua Wang Mingsheng Chen Yeisoo Yu Rod A. Wing Wen Wang Fengyi Hu | 2015 | Molecular Plant2015，8，11： | 1 |
| 9 | Distribution of shrublands in relation to soil and climate in mid-subtropical China显示文摘Aims Understanding relationships between vegetation and environments is of importance for ecosystem restoration and management.However,information on how environments influence the floristic patterns of shrublands is lack,especially in the subtropical China.In this study,we explored how environments regulate species composition of shrublands at landscape scale in mid-subtropical China.Methods We investigated species composition and measured the climate and soil environments for 207 shrubland plots in mid-subtropical China(24°39′-30°08′N,108°47′-114°15′E).We applied a hierarchical cluster analysis and indicator species analysis based on the Bray-Curtis similarity index to identify the main shrubland types and employed principal coordinate analysis(PCoA)to explore the relationship between floristic composition and environment.Important Findings We identified four shrubland types occurring in different environmental conditions.Montane shrubland,dominated by species suitable for cool climates(e.g.Rhododendron simsii),were distributed in steep areas at comparatively high altitudes;foothill shrubland,dominated by mesophilous species(e.g.Loropetalum chinense),were distributed in low mountains and hills;pioneer shrubland,dominated by fast grow and short-life cycles species(e.g.Rhus chinensis),were distributed at low altitudes with dense population;and finally,limestone shrubland,dominated by calcicole plants(e.g.Coriaria nepalensis),were distributed in the extensive karst areas.Communities occurring in high pH soils were completely separated from those in low pH soils according to the hierarchical cluster analysis.PCoA ordination associated the four types with distinct edaphic and climatic gradients.Soil pH explained 63.3%of variation in PCoA,followed by soil depth and soil bulk density. | Jiaxiang Li Gaoming Xiong Wenting Xu Zongqiang Xie | 2016 | Journal of Plant Ecology2016，9，4： | 1 |
| 10 | Calcium Homeostasis in Parkinson’s Disease:From Pathology to Treatment显示文摘Disturbances of Ca^(2+)homeostasis have been reported to be associated with the development of Parkinson's disease(PD)(Fig.1),which is characterized by the selective vulnerability of dopaminergic neurons in the substantia nigra pars compacta(SNpc).Different from the dopaminergic neurons in the ventral tegmental area(VTA),which mainly rely on hyperpolarization-activated cyclic nucleotide-gated/voltagegated channels for pacing and have a strong Ca^(2+)-buffering capacity. | Jingxian Zhang Qingqing Shen Yue Ma Lin Liu Wenting Jia Leilei Chen Junxia Xie | 2022 | Neuroscience Bulletin2022，38，10： | 0 |
| 11 | Accelerating hybrid and compact neural networks targeting perception and control domains with coarse-grained dataflow reconfiguration显示文摘Driven by continuous scaling of nanoscale semiconductor technologies,the past years have witnessed the progressive advancement of machine learning techniques and applications.Recently,dedicated machine learning accelerators,especially for neural networks,have attracted the research interests of computer architects and VLSI designers.State-of-the-art accelerators increase performance by deploying a huge amount of processing elements,however still face the issue of degraded resource utilization across hybrid and non-standard algorithmic kernels.In this work,we exploit the properties of important neural network kernels for both perception and control to propose a reconfigurable dataflow processor,which adjusts the patterns of data flowing,functionalities of processing elements and on-chip storages according to network kernels.In contrast to stateof-the-art fine-grained data flowing techniques,the proposed coarse-grained dataflow reconfiguration approach enables extensive sharing of computing and storage resources.Three hybrid networks for MobileNet,deep reinforcement learning and sequence classification are constructed and analyzed with customized instruction sets and toolchain.A test chip has been designed and fabricated under UMC 65 nm CMOS technology,with the measured power consumption of 7.51 mW under 100 MHz frequency on a die size of 1.8×1.8 mm^2. | Zheng Wang Libing Zhou Wenting Xie Weiguang Chen Jinyuan Su Wenxuan Chen Anhua Du Shanliao Li Minglan Liang Yuejin Lin Wei Zhao Yanze Wu Tianfu Sun Wenqi Fang Zhibin Yu | 2020 | Journal of Semiconductors2020，41，2： | 0 |
| 12 | MicroRNA-181a is elevated by 10-hydroxycamptothecin and represses lung carcinoma progression by downregulating FOXP1显示文摘Tumor progression is usually characterized by proliferation,migration,and angiogenesis,which is essential for supplying both nutrients and oxygen to the tumor cells.Therefore,targeting angiogenesis has been considered a promising therapeutic strategy for cancer prevention and treatment.In the present study,we demonstrated that in addition to suppressing lung cancer cell proliferation and migration in vitro,10-hydroxycamptothecin(10-HCPT)is also capable of inhibiting angiogenesis in vivo with a miR-181a-dependent manner.Mechanistically,by upregulating miR-181a,which in turn downregulating FOXP1,10-HCPT can inhibit the PI3K/Akt/ERK signaling pathwaymediated angiogenesis.Furthermore,reduced levels of miR-181a have been found in both lung cancer cell lines and xenograft with concurrently elevated levels of FOXP1,VEGF,bFGF,and HDGF.Consistent with the findings from the in vitro experiments,miR-181a impairs neovascularization in our xenograft model.In summary,our findings have not only established the anti-oncogenic role of miR-181a in lung cancer angiogenesis but also suggest that 10-HCPT could be a potential therapeutic reagent for lung cancer treatment. | LI PAN WENTING YI DONGMIN LIANG YULONG ZHAO RANRAN WANG PINGYU WANG YOUJIE LI JIAXUAN XIN YUNFEI YAN SHUYANG XIE | 2022 | BIOCELL2022，46，2： | 0 |
| 13 | Photochemical graft of γ-cyclodextrin's interior leading to in-situ charge-transfer complexes with unusual regioselectivity and its application in 3D photo-printing显示文摘Photoirradiation of anthraquinone(AQ)derivatives withγ-cyclodextrin(γ-CD)in aqueous solution led to aγ-CD derivative with a 9,10-dihydroxylanthracene grafting unprecedentedly at the 5′-position of one glucoside ofγ-CD in high efficiency.Meanwhile,another AQ enters into the remaining space of the 9,10-dihydroxylanthracene-occupiedγ-CD cavity to in-situ form a selfincluded quinhydrone charge transfer(CT)complex.The structure of the supramolecular CT complex was unambiguously demonstrated by 1 D and 2 D NMR(^(1)H NMR,^(13)C NMR,DEPT,^(1)H-^(1)H COSY,HSQC,HMBC,TOCSY,and ROESY)spectroscopies,which revealed a highly stereoselective stacking of the quinhydrone pairs in theγ-CD cavity.The supramolecular CT complex showed an unusually high binding affinity and improved oxidation resistance.Polyacrylamides bearingγ-CD or anthraquinone were respectively synthesized by co-polymerization of acrylamide with the corresponding monomer.Photoirradiation of aqueous mixtures containing these two types of polymers led to gelation,which was applied to 3 D photo-printing of soft materials. | Dongjing Zhang Wenting Liang Jigao Yi Jinlei Chen Yongjun Lv Ting Zhao Chao Xiao Xiangyu Xie Wanhua Wu Cheng Yang | 2022 | Science China Chemistry2022，65，6： | 0 |
| 14 | Effects of Rosa roxburghii&edible fungus fermentation broth on immune response and gut microbiota in immunosuppressed mice显示文摘With the rise of probiotics fermentation in food industry,fermented foods have attracted worldwide attention.In this study,protective effects of Rosa roxburghii&edible fungus fermentation broth(REFB)on immune function and gut health in Cyclophosphamide induced immunosuppressed mice were investigated.Results showed that REFB could improve the immune organ index,and promote the proliferation and differentiation of splenic T lymphocytes.In addition,it attenuated intestinal mucosal damage and improved intestinal cellular immunity.REFB administration also up-regulated the expression of IL-4,INF-γ,TNF-α,T-bet and GATA-3 mRNA in small intestine.Furthermore,administration of REFB modulated gut microbiota composition and increased the relative abundance of beneficial genus,such as Bacteroides.It also increased the production of fecal short-chain fatty acids.These indicate that REFB has the potential to improve immunity,alleviate intestinal injury and regulate gut microbiota in immunosuppressed mice. | Dechang Xu Jielun Hu Yadong Zhong Yanli Zhang Wenting Liu Shaoping Nie Mingyong Xie | 2024 | Food Science and Human Wellness2024，13，1： | 0 |
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