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| 1 | 42,573 cases of hepatectomy in China: a multicenter retrospective investigation显示文摘Hepatectomy is currently routinely performed in most hospitals in China. China owns the largest population of liver diseases and the biggest number of liver resection cases. A nationwide multicenter retrospective investigation involving 112 hospitals was performed, and focused on liver resection for patients with hepatocellular carcinoma(HCC). 42,573 cases of hepatectomy were enrolled, and 18,275 valid cases of liver resection for HCC patients were selected for statistical analysis. The epidemiology of HCC, distribution of hepatectomy, postoperative complications and prognosis were finally analyzed. In the 18,275 HCC patients,81% had hepatitis B virus infection and 10% had hepatitis C virus infection. 38% of the HCC patients had normal Alphafetoprotein(AFP) level, and other 35% had an AFP level lower than 400 ng mL^(-1). In the study period, 97% of the hepatectomy for HCC were treated with open surgery, and 23.81% had vascular exclusion techniques. The operation time was(191.7±105.6) min,the blood loss was(546.0±562.8) m L, and blood transfusion was(543.0±1,035.2) m L. The median survival for HCC patients was 631 days, with 1-, 3-, and 5-year overall survival of 73.2%, 28.8% and 19.6%, respectively. Liver cirrhosis, multiple nodules,tumor thrombosis and high AFP level were risk factors that affect postoperative survival. | Binhao Zhang Bixiang Zhang Zhiwei Zhang Zhiyong Huang Yifa Chen Minshan Chen Ping Bie Baogang Peng Liqun Wu Zhiming Wang Bo Li Jia Fan Lunxiu Qin Ping Chen Jingfeng Liu Zhe Tang Jun Niu Xinmin Yin Deyu Li Songqing He Bin Jiang Yilei Mao Weiping Zhou Xiaoping Chen | 2018 | Science China(Life Sciences)2018，61，6： | 39 |
| 2 | An overview of the use of plastic-film mulching in China to increase crop yield and water-use efficiency显示文摘Since 1990,crop yields have stagnated in many parts of the world,posing a significant challenge to global food security[1].As such;innovative solutions are needed to increase the resource-use efficiency of cropping systems to produce more grains per unit area. | Dongbao Sun Haigang Li Enli Wang Wenqing He Weiping Hao Changrong Yan Yuzhong Li Xurong Mei Yanqing Zhang Zhanxiang Sun Zhikuan Jia Huaiping Zhou Tinglu Fan Xucheng Zhang Qin Liu Fengju Wang Chaochun Zhang Jianbo Shen Qingsuo Wang Fusuo Zhang | 2020 | National Science Review2020，7，10： | 19 |
| 3 | Microbiota transplantation reveals beneficial impact of berberine on hepatotoxicity by improving gut homeostasis显示文摘Berberine has been shown to reduce acute liver injury although the underlying mechanism is not fully understood. Because of the anatomic connection, the liver is constantly exposed to gut-derived bacterial products and metabolites. In this study, we showed that berberine has beneficial effects on both hepatotoxicity and intestinal damage in a rat model of chronic or acute liver injury. Microbiota transplantation from the rats with chronic hepatotoxicity could aggravate acute hepatotoxicity in mice treated with diethylnitrosamine(DEN). In rat models with gut homeostasis disruption induced by penicillin or dextran sulfate sodium(DSS), their fecal microbiota could also cause an enhanced hepatotoxicity of recipient mice. When treated with berberine,the DSS-induced enteric dysbacteriosis could be mitigated and their fecal bacteria were able to reduce acute hepatotoxicity in recipient mice. This study indicates that berberine could improve intestinal dysbacteriosis, which reduces the hepatotoxicity caused by pathological or pharmacological intervention. Fecal microbiota transplantation might be a useful method to directly explore homeostatic alteration in gut microbiota. | Chenjie Qin Huilu Zhang Linghao Zhao Min Zeng Weijian Huang Gongbo Fu Weiping Zhou Hongyang Wang Hexin Yan | 2018 | Science China(Life Sciences)2018，61，12： | 8 |
| 4 | Progress of Jinping Underground laboratory for Nuclear Astrophysics(JUNA)显示文摘Jinping Underground laboratory for Nuclear Astrophysics(JUNA) will take the advantage of the ultra-low background of CJPL lab and high current accelerator based on an ECR source and a highly sensitive detector to directly study for the first time a number of crucial reactions occurring at their relevant stellar energies during the evolution of hydrostatic stars. In its first phase, JUNA aims at the direct measurements of^(25)Mg(p,γ)^(26)Al,^(19)F(p,α)^(16)O,^(13)C(α,n)^(16)O and ^(12)C(α,γ)^(16)O reactions. The experimental setup,which includes an accelerator system with high stability and high intensity, a detector system, and a shielding material with low background, will be established during the above research. The current progress of JUNA will be given. | WeiPing Liu ZhiHong Li JiangJun He XiaoDong Tang Gang Lian Zhu An JianJun Chang Han Chen QingHao Chen XiongJun Chen ZhiJun Chen BaoQun Cui XianChao Du ChangBo Fu Lin Gan Bing Guo GuoZhu He Alexander Heger SuQing Hou HanXiong Huang Ning Huang BaoLu Jia LiYang Jiang Shigeru Kubono JianMin Li KuoAng Li Tao Li YunJu Li Maria Lugaro XiaoBing Luo HongYi Ma ShaoBo Ma DongMing Mei YongZhong Qian JiuChang Qin Jie Ren YangPing Shen Jun Su LiangTing Sun WanPeng Tan Isao Tanihata Shuo Wang Peng Wang YouBao Wang Qi Wu ShiWei Xu ShengQuan Yan LiTao Yang Yao Yang XiangQing Yu Qian Yue Sheng Zeng HuanYu Zhang Hui Zhang LiYong Zhang NingTao Zhang QiWei Zhang Tao Zhang XiaoPeng Zhang XueZhen Zhang ZiMing Zhang Wei Zhao Zuo Zhao Chao Zhou | 2016 | Science China(Physics,Mechanics & Astronomy)2016，59，4： | 3 |
| 5 | Identification of miRNomes in Human Liver and Hepatocellular Carcinoma Reveals miR-199a/b-3p as Therapeutic Target for Hepatocellular Carcinoma显示文摘 | Jin Hou Li Lin Weiping Zhou Zhengxin Wang Guoshan Ding Qiongzhu Dong Lunxiu Qin Xiaobing Wu Yuanyuan Zheng Yun Yang Wei Tian Qian Zhang Chunmei Wang Qinghua Zhang Shi-Mei Zhuang Limin Zheng Anmin Liang Wenzhao Tao Xuetao Cao | 2011 | Cancer Cell2011，，2： | 3 |
| 6 | Passively Q-switched erbium doped fiber laser using a gold nanostars based saturable absorber显示文摘In this paper, we propose and demonstrate an all-fiber passively Q-switched erbium doped fiber laser(EDFL) by using gold nanostars(GNSs) as a saturable absorber(SA) for the first time, to the best of our knowledge. In comparison with other gold nanomorphologies, GNSs have multiple localized surface plasmon resonances, which means that they can be used to construct wideband ultrafast pulse lasers. By inserting the GNS SA into an EDFL cavity pumped by a 980 nm laser diode, a stable passively Q-switched laser at 1564.5 nm was achieved for a threshold pump power of 40 mW. By gradually increasing the pump power from 40 to 120 mW, the pulse duration decreases from 12.8 to 5.3 μs and the repetition rate increases from 10 to 17 kHz. Our results indicate that the GNSs are a promising SA for constructing pulse lasers. | ZHE KANG MINGYI LIU ZHENWEI LI SIQING LI ZHIXU JIA CHENGZHI LIU WEIPING QIN GUANSHI QIN | 2018 | Photonics Research2018，6，6： | 2 |
| 7 | Controlled synthesis and luminescence properties from cubic to hexagonal NaYF 4 :Ln 3+ (Ln=Eu and Yb/Tm) microcrystals显示文摘 | Guofeng Wang Weiping Qin Jisen Zhang Lili Wang Guodong Wei Peifen Zhu Ryongjin Kim | 2008 | Journal of Alloys and Compounds2008，，1： | 2 |
| 8 | Photoluminescence from surfactant-assembled Y2O3:Eu nanotubes显示文摘 | Wu Changfeng Qin Weiping Qin Guanshi | 2003 | Appl Phys Lett2003，82，： | 1 |
| 9 | A facility for production and utilization of radioactive beams显示文摘 | BAI Xixiang LIU Weiping QIN Jiuchang | 1995 | Nucl Phys1995，588，： | 1 |
| 10 | Synthesis and field emission of MoO 3 nanoflowers by a microwave hydrothermal route显示文摘 | Guodong Wei Weiping Qin Daisheng Zhang Guofeng Wang Ryongjin Kim Kezhi Zheng Lili Wang | 2009 | Journal of Alloys and Compounds2009，，1： | 1 |
| 11 | TLR4 is required for the obesity-induced pancreatic beta cell dysfunction显示文摘肥胖是为类型 2 糖尿病的一个重要导致因素。然而,位于 high-fat-(HF ) 下面的机制在胰腺的贝它房间机能障碍的导致食谱的肥胖仍然是不清楚的。像使用费的 receptor-4 (TLR4 ) 是天生的免疫的一个关键调停人。在导致肥胖的胰腺的贝它房间机能障碍调查 TLR4 的效果,我们使用了男糖尿病患者(db/db ) ,肥胖(ob/ob ) 老鼠, TLR4 野的类型(WT ) ,和用正常饮食或 HF 被喂的 TLR4 大美人老鼠节食 24 个星期。在胰腺的小岛的 TLR4 和 TLR4 mRNA 水平的 Immunostaining 被估计。从生物特征,葡萄糖忍耐测试,胰岛素忍耐测试,和胰岛素版本测试的结果证明胰腺的小岛的功能在喂 HF 的 TLR4 WT 老鼠被损害,但是在喂 HF 的 TLR4 被保护缺乏(TLR4/) 老鼠。由电子显微镜察觉,我们观察了能分泌的泡在喂 HF 的 TLR4 WT 老鼠增加了的那贝它房间胰岛素。在喂 HF 的 TLR4/ 老鼠的贝它房间的超微结构在正常食物类似于那喂食谱的 TLR4 WT 老鼠。然后,由使用主要胰腺的小岛的刺激葡萄糖的胰岛素分泌物试金证明在喂 HF 的 TLR4/ 鼠标的胰腺的小岛的分泌物函数在喂 HF 的 TLR4 WT 鼠标比那好。而且,在喂 HF 的 TLR4/ 老鼠, IL-6 的 mRNA 层次, TNF- ,和 MCP-1,在胰腺的小岛的基因是比在喂 HF 的 TLR4 WT 老鼠的那些显著地低的。与在基因表示,喂 HF 的 TLR4 WT 老鼠然而并非喂 HF 的 TLR4/ 的变化一致老鼠在胰腺的岛展出了巨噬细胞侵略。一起拿,我们的数据显示了那 HF 导致食谱的肥胖能刺激在胰腺的贝它房间的表面上定位的 TLR4 的起来规定,并且随后导致巨噬细胞的招募进胰腺的小岛,它最后导致胰腺的贝它房间机能障碍。这个过程是涉及导致肥胖的胰腺的贝它房间机能障碍的可能的机制。 | Juan Li Lei Chen Ye Zhang Weiping J. Zhang Wenyan Xu Yi Qin Jin Xu Dajin Zou | 2013 | Acta Biochimica et Biophysica Sinica2013，45，12： | 1 |
| 12 | Synthesis and spectral properties of Eu 3+ -doped YF 3 nanobundles显示文摘 | Guofeng Wang Weiping Qin Jisen Zhang Jishuang Zhang Yan Wang Chunyan Cao Lili Wang Guodong Wei Peifen Zhu Ryongjin Kim | 2008 | Journal of Fluorine Chemistry2008，，7： | 1 |
| 13 | Identification of miRNomes in Human Liver and Hepatocellular Carcinoma Reveals miR-199a/b-3p as Therapeutic Target for Hepatocellular Carcinoma显示文摘 | Jin Hou Li Lin Weiping Zhou Zhengxin Wang Guoshan Ding Qiongzhu Dong Lunxiu Qin Xiaobing Wu Yuanyuan Zheng Yun Yang Wei Tian Qian Zhang Chunmei Wang Qinghua Zhang Shi-Mei Zhuang Limin Zheng Anmin Liang Wenzhao Tao Xuetao Cao | 2011 | Cancer Cell2011，，2： | 1 |
| 14 | Chiral stability of synthetic pyrethroid insecticides显示文摘 | Liu Weiping Qin Sujie Gan Jianying | 2005 | Journal of Agricultural and Food Chemistry2005，，： | 1 |
| 15 | Rapid prototyping assisted surgery planning and custom implant design 显示文摘 | Singare S Lian Qin Wang Weiping | 2009 | Rapid Prototypin Journal2009，15，1： | 1 |
| 16 | 显示文摘 | Chen Baojiu Kong Xianggui Qin Weiping | 1999 | Chinese Journal of luminescence1999，20，4： | 1 |
| 17 | Size-dependent upconversion luminescence in YF3: Yb^3+/Tm^3+ nanobundles 显示文摘 | Wang Guofeng Qin Weiping Wei Guodong Zhu Peifen Kim Ryongjin | 2009 | Journal of Fluorine Chemistry2009，129，11： | 1 |
| 18 | Synthesis and upconversion luminescence properties of YF3 : Yb^3+/Tm^3+ octahedral nanoerystals 显示文摘 | Wang Guofeng Qin Weiping Wei Guodong Wang Lili Zhu Peifen Kim Ryong jin Zhang Daisheng Ding Fuheng Zheng Kezhi | 2009 | Journal of Fluorine Chemistry2009，130，2： | 1 |
| 19 | Seperation and aquatic toxicity of enantiomers of synthetic pyrethroid insecticides 显示文摘 | LIU Weiping Gan J Jay QIN Sujie | 2005 | Chiraty2005，17，： | 1 |
| 20 | A Facility for Production and Utilization of Radioactive Beams显示文摘 | Bai Xixiang Liu Weiping Qin Jiuchang | 1995 | Nucl Phys1995，588，： | 1 |
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