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| 1 | An overview of the use of plastic-film mulching in China to increase crop yield and water-use efficiency显示文摘Since 1990,crop yields have stagnated in many parts of the world,posing a significant challenge to global food security[1].As such;innovative solutions are needed to increase the resource-use efficiency of cropping systems to produce more grains per unit area. | Dongbao Sun Haigang Li Enli Wang Wenqing He Weiping Hao Changrong Yan Yuzhong Li Xurong Mei Yanqing Zhang Zhanxiang Sun Zhikuan Jia Huaiping Zhou Tinglu Fan Xucheng Zhang Qin Liu Fengju Wang Chaochun Zhang Jianbo Shen Qingsuo Wang Fusuo Zhang | 2020 | National Science Review2020，7，10： | 19 |
| 2 | Interpretation of breast cancer screening guideline for Chinese women显示文摘Breast cancer is the most common malignant tumor in Chinese women.Early screening is the best way to improve the rates of early diagnosis and survival of breast cancer patients.The peak onset age for breast cancer in Chinese women is considerably younger than those in European and American women.It is imperative to develop breast cancer screening guideline that is suitable for Chinese women.By summarizing the current evidence on breast cancer screening in Chinese women,and referring to the latest guidelines and consensus on breast cancer screening in Europe,the United States,and East Asia,the China Anti-Cancer Association and National Clinical Research Center for Cancer(Tianjin Medical University Cancer Institute and Hospital)have formulated population-based guideline for breast cancer screening in Chinese women.The guideline provides recommendations on breast cancer screening for Chinese women at average or high risk of breast cancer according to the following three aspects:age of screening,screening methods,and screening interval.This article provides more detailed information to support the recommendations in this guideline and to provide more direction for current breast cancer screening practices in China. | Yubei Huang Zhongsheng Tong Kexin Chen Ying Wang Peifang Liu Lin Gu Juntian Liu Jinpu Yu Fengju Song Wenhua Zhao Yehui Shi Hui Li Huaiyuan Xiao Xishan Hao | 2019 | Cancer Biology & Medicine2019，16，4： | 10 |
| 3 | Roles of low?density lipoproteinreceptor?related protein 1 in tumors显示文摘Low-density lipoprotein receptor-related protein 1(LRP1,also known as CD91),a multifunctional endocytic and cell signaling receptor,is widely expressed on the surface of multiple cell types such as hepatocytes,fibroblasts,neurons,astrocytes,macrophages,smooth muscle cells,and malignant cells.Emerging in vitro and in vivo evidence demonstrates that LRP1 is critically involved in many processes that drive tumorigenesis and tumor progression.For example,LRP1 not only promotes tumor cell migration and invasion by regulating matrix metalloproteinase(MMP)-2and MMP-9 expression and functions but also inhibits cell apoptosis by regulating the insulin receptor,the serine/threonine protein kinase signaling pathway,and the expression of Caspase-3.LRPI-mediated phosphorylation of the extracellular signal-regulated kinase pathway and c-jun N-terminal kinase are also involved in tumor cell proliferation and invasion.In addition,LRP1 has been shown to be down-regulated by microRNA-205 and methylation of LRP1CpG islands.Furthermore,a novel fusion gene,LRP1-SNRNP25,promotes osteosarcoma cell invasion and migration.Only by understanding the mechanisms of these effects can we develop novel diagnostic and therapeutic strategies for cancers mediated by LRP1. | Peipei Xing Zhichao Liao Zhiwu Ren Jun Zhao Fengju Song Guowen Wang Kexin Chen Jilong Yang | 2016 | Chinese Journal of Cancer2016，35，1： | 4 |
| 4 | Model for Paleoearthquake Recurrence Along Baying Segment of the North Margin Fault of Fanshan Basin in Hebei Province显示文摘Based on the measurement of faulted geomorphic surfaces,large trench logging and systematic chronostratigraphic sampling,we suggest that the total slip amount along the Baying segment of the north margin fault of Fanshan Basin since 90 ka B.P.is 34 m.Nine paleoseismic events occurred in the last 75 ka.Among them,the four events A,B,C,and D revealed by the large trench were dated at 28 ka,14 ka,7.5 ka,and 656 B.P.,respectiv eJy.The model for paleoearthquake recurrence along the segment may have two stages; in the stage from 90 ka to 14 ka B.P.,the 'time-predictable model' is suitable,while in the stage from 14 ka B.P.to now,the 'displacement-attenuation model' applies. | Ran Yongkang,Fang Zhongjing,Duan Ruitao,Li Zhiyi,Wang Jingbo,Yang Zhe,Ji Fengju,and Li JianpingInsatute of Geology,State Seismologlcal Bureau,Beijing 100029,China | 1996 | Earthquake Research in China1996，10，1： | 3 |
| 5 | Biological improvement of saline alkali soil reference system:A review显示文摘This work presents a reference system overview to improve the efficiency of biological improvement of saline-alkali soil developed during the last thirty years, ranging from connotation, general methods and species, soil desalination, soil structure, soil organic content, microbial flora, enzyme activity, yield and economic benefits. The reference system presented is divided into three main groups: suitable varieties, suitable cultivation measures, and a comprehensive evaluation system.There has been a lot of research on biological improvement of saline alkali soil, but these studies are very fragmented and lack a comprehensive standard system. Also, there is a lack of practical significance, particularly with regard to optimal species, densities and times of sowing for particular regions. On the other hand, the corresponding cultivation measure is very important. Therefore, a reference system plays an important role to the effect of biological improvement of saline alkali soil. | XueQin Wang Xu Xing FengJu Zhang Kong Xin | 2018 | Research in Cold and Arid Regions2018，10，6： | 2 |
| 6 | Corneal subbasal nerve fiber regeneration in myopic patients after laser in situ keratomileusis显示文摘A total of 26 myopic patients(52 eyes) underwent laser in situ keratomileusis.In vivo confocal microscopy revealed that most of the regenerated corneal subbasal nerve fibers in the corneal flap originated from the stump of corneal subbasal nerve fibers outside the ablation zone and extended towards the center of the cornea in all patients.Meanwhile,new fibers were also found to directly regenerate from deep in the stroma in some cases.Approximately 94% of regenerated corneal subbasal nerve fibers(73/78 eyes) regrew vertically into the peripheral central 6-mm circle area 1 month after surgery,78%(28/36 eyes) grew into the central 3-6 mm area at 2 months,and 23% into the central 3-mm circle area at 3 months.In addition,there was no significant difference in corneal subbasal nerve fiber regenerative capacity between the basic fibroblast growth factor group and the 20%(v/v) deproteinized extract of calf blood group.The majority of corneal subbasal nerve fiber regeneration occurred from the stump of corneal subbasal nerve fibers outside the corneal flap,and the remaining growth occurred deep within the stroma. | Shijing Deng Mengmeng Wang Fengju Zhang Xuguang Sun Wenbo Hou Ning Guo | 2012 | Neural Regeneration Research2012，7，20： | 1 |
| 7 | Anti-melanoma action of small molecular peptides derived from Brucea javanica(L.)Merr.globulin in vitro显示文摘Objective:The morbidity of malignant melanoma keeps increasing annually.It has high risks of metastasis,drug resistance,and poor prognosis in clinics.Moreover,the available medicines used commonly,such as dacarbazine,temozolomide,the v-Raf murine sarcoma viral oncogene homolog B1(BRAF)inhibitor vemurafenib,and the programmed cell death protein 1 inhibitor pembrolizumab,have some limitations at some extent.Therefore,a more effective therapeutic strategy is still urgently necessary.Methods:In this study,Brucea javanica(L.)Merr.globulins were hydrolyzed with pepsin,then ultra-filtrated to collect small molecular peptides(≤3 kDa).The peptides were then analyzed by antiproliferative assay,cell-cycle distribution,apoptosis assay,and in vitro wound-scratch assay.Finally,western blotting was conducted to elucidate the underlying anti-melanoma mechanism.Results:The small molecular peptide from B.javanica significantly inhibited malignant melanoma cell proliferation with the IC_(50) of 2.72 mg/mL for 72 h.Further analysis indicated that B.javanica peptides arrested cell cycle at the S and G2/M phases and induced apoptosis by upregulating p21,p53,Bax,caspase-3,and cleaved PARP while downregulating Bcl-2 expression.The inhibitory migration effects were also confirmed by wound-healing assay.Conclusion:The small molecular biopeptides from B.javanica may be a promising bioactive agent candidate for melanoma treatment. | Yi Zhao Huiyun Wang Yanyan Yin Haoyu Shi Dong Wang Fengjue Shu Rongchun Wang Lingzhi Wang | 2022 | Journal of Traditional Chinese Medical Sciences2022，9，1： | 1 |
| 8 | A meta-analysis of the association between induced abortion and breast cancer risk among Chinese females显示文摘 | Yubei Huang Xiaoliang Zhang Weiqin Li Fengju Song Hongji Dai Jing Wang Ying Gao Xueou Liu Chuan Chen Ye Yan Yaogang Wang Kexin Chen | 2014 | Cancer Causes & Control2014，，2： | 1 |
| 9 | Impact of recent climatic change on the yield of winter wheat at low and high altitudes in semi-arid northwestern China显示文摘 | Guoju Xiao Qiang Zhang Yubi Yao Hong Zhao Runyuan Wang Huzhi Bai Fengju Zhang | 2008 | Agriculture Ecosystems and Environment2008，，1： | 1 |
| 10 | Automatic LOD selection using viewpoint entropy显示文摘Discrete Level of Detail (LOD) strategy is an effective solution for balancing the inherentcontradiction between quality and speed in computer graphics. However, application ofthis strategy requires both the appropriate selection approach and the visually comfortable transition procedure to reduce the popping effects introduced by switching betweendifferent levels. In this paper, a novel automatic LOD selection method based on viewpoint entropy was proposed. Firstly, the traditional calculation method of viewpointentropy contained in a scene was improved for the preprocessing of LOD models. Then,the runtime rendering scheme combined with our selection method was designed forbalance of frame rate during real-time rendering, and a novel smoothing LOD transitionstrategy based on Alternate Frame Rendered (ALR) was put forward for eliminationof popping effects. Finally, an example of complex scene combined with our proposalwas researched to verify its real-time performance and ability in holding continuity ofrendered images. Experimental studies show the effectiveness for stabilizing frame rateand improvements in reducing loss of continuity. | Xiaodong Wang Fengju Kang Hao Gu | 2017 | International Journal of Modeling, Simulation, and Scientific Computing2017，8，2： | 0 |
| 11 | Effect of Multi-parameter Environmental Factors on Cucumber Leaf Surface Wetness显示文摘In this study, artificial leaf resistance was used to simulate leaf wetness. Specific to the solar greenhouse environment in Tianjin, microclimate monitoring equipment was installed for the collection of temperature group and humidity group data, as well as solar radiation and leaf wetness in the greenhouse. In order to reduce the complexity of multivariate factor prediction and ensure the richness of selected data types, correlation analysis was made to the 2 groups of data, screening 5 000 groups of data, including the humidity group data RH, RH_(20), RH_(40), temperature group data T, T_(20), T_(40), and solar radiation W. The data were then analyzed by principal component analysis, screening out 4 groups of principal components to show the leaf wetness index. | Chunyang QIAN Jianchun WANG Fengju LI Zhiwen SONG Yan WANG | 2019 | Agricultural Biotechnology2019，8，2： | 0 |
| 12 | Low Complexity Detection Algorithms Based on ADMIN for Massive MIMO显示文摘This paper proposes the alternating direction method of multipliers-based infinity-norm(ADMIN) with threshold(ADMIN-T) and with percentage(ADMIN-P) detection algorithms,which make full use of the distribution of the signal to interference plus noise ratio(SINR) for an uplink massive MIMO system.The ADMIN-T and ADMIN-P detection algorithms are improved visions of the ADMIN detection algorithm,in which an appropriate SINR threshold in the ADMIN-T detection algorithm and a certain percentage in the ADMIN-P detection algorithm are designed to reduce the overall computational complexity.The detected symbols are divided into two parts by the SINR threshold which is based on the cumulative probability density function(CDF) of SINR and a percentage,respectively.The symbols in higher SINR part are detected by MMSE.The interference of these symbols is then cancelled by successive interference cancellation(SIC).Afterwards the remaining symbols with low SINR are iteratively detected by ADMIN.The simulation results show that the ADMIIN-T and the ADMIN-P detection algorithms provide a significant performance gain compared with some recently proposed detection algorithms.In addition,the computational complexity of ADMIN-T and ADMIN-P are significantly reduced.Furthermore,in the case of same number of transceiver antennas,the proposed algorithms have a higher performance compared with the case of asymmetric transceiver antennas. | Shuchao Mi Jianyong Zhang Fengju Fan Baorui Yan Muguang Wang | 2023 | China Communications2023，20，11： | 0 |
| 13 | Development and Capacity Forecast of China Rubber Raw Materials显示文摘The '11th Five-Year Plan' period is the most glorious period in the history of China raw materials such as NR and SR. During the '12th Five-Year Plan' period,the rubber raw materials will enter an important period of great development in technology, product and output. | Wang Fengju | 2011 | 中国橡胶2011，27，16： | 0 |
| 14 | TPI Development & Application Gained Ground显示文摘On April 28, 'TPI Development & Application Seminar' organized by TPI Industry Technical Innovation Strategic Alliance was held in Qingdao.With combination of keynote speech and panel discussion, | Wang Fengju | 2013 | 中国橡胶2013，29，12： | 0 |
| 15 | Researches on preconditioned wire arrayZpinches in Xi’an Jiaotong University显示文摘The dynamics of wire array Z pinches are greatly affected by the initial state of the wires,which can be preconditioned by a prepulse current.Recent advances in experimental research on preconditioned wire array Z pinches at Xi’an Jiaotong University are presented in this paper.Single-wire explosion experiments were carried out to check the state of the preconditioning and to obtain the current parameters needed for wire gasification.Double-wire explosion experiments were conducted to investigate the temporal evolution of the density distribution of the two gasified wires.Based on the results of these experiments,a double-pulse Z-pinch facility,Qin-1,in which a 10 kA prepulse current was coupled with the 0.8 MA main current was designed and constructed.Wire arrays of different wire materials,including silver and tungsten,can be preconditioned by the prepulse current to a gaseous state.Implosion of the two preconditioned aluminum wires exhibited no ablation and little trailing mass. | Jian Wu Yihan Lu Fengju Sun Xiaofeng Jiang Zhiguo Wang Daoyuan Zhang Xingwen Li Aici Qiu | 2019 | Matter and Radiation at Extremes2019，4，3： | 0 |
| 16 | Improved diagnosis of thyroid cancer aided with deep learning applied to sonographic text reports:a retrospective,multi-cohort,diagnostic study显示文摘Objective:Large volume radiological text data have been accumulated since the incorporation of electronic health record(EHR)systems in clinical practice.We aimed to determine whether deep natural language processing algorithms could aid radiologists in improving thyroid cancer diagnosis.Methods:Sonographic EHR data were obtained from the EHR database.Pathological reports were used as the gold standard for diagnosing thyroid cancer.We developed thyroid cancer diagnosis based on natural language processing(THCaDxNLP)to interpret unstructured sonographic text reports for thyroid cancer diagnosis.We used the area under the receiver operating characteristic curve(AUROC)as the primary metric to measure the performance of the THCaDxNLP.We compared the performance of thyroid ultrasound radiologists aided with THCaDxNLP vs.those without THCaDxNLP using 5 independent test sets.Results:We obtained a total number of 788,129 sonographic radiological reports.The number of thyroid sonographic data points was 132,277,18,400 of which were thyroid cancer patients.Among the 5 test sets,the numbers of patients per set were 439,186,82,343,and 171.THCaDxNLP achieved high performance in identifying thyroid cancer patients(the AUROC ranged from 0.857–0.932).Thyroid ultrasound radiologists aided with THCaDxNLP achieved significantly higher performances than those without THCaDxNLP in terms of accuracy(93.8%vs.87.2%;one-sided t-test,adjusted P=0.003),precision(92.5%vs.86.0%;P=0.018),and F1 metric(94.2%vs.86.4%;P=0.007).Conclusions:THCaDxNLP achieved a high AUROC for the identification of thyroid cancer,and improved the accuracy,sensitivity,and precision of thyroid ultrasound radiologists.This warrants further investigation of THCaDxNLP in prospective clinical trials. | Qiang Zhang Sheng Zhang Jianxin Li Yi Pan Jing Zhao Yixing Feng Yanhui Zhao Xiaoqing Wang Zhiming Zheng Xiangming Yang Lixia Liu Chunxin Qin Ke Zhao Xiaonan Liu Caixia Li Liuyang Zhang Chunrui Yang Na Zhuo Hong Zhang Jie Liu Jinglei Gao Xiaoling Di Fanbo Meng Wei Ji Meng Yang Xiaojie Xin Xi Wei Rui Jin Lun Zhang Xudong Wang Fengju Song Xiangqian Zheng Ming Gao Kexin Chen Xiangchun Li | 2022 | Cancer Biology & Medicine2022，19，5： | 0 |
| 17 | A 26ka Continuous Stratigraphic Record of Surface Rupturing Earthquakes in Drill Logs Across the Xiadian Fault,Hebei Province,China显示文摘This paper deals wiah a new method for identification of long-term slip behavior of a conceaiedfault in a plain area from tectono-stratigraphic and chronological data obtained by drilling.Chronological determination and lithological analysis and correlation of sediments in stratigraphic colunms of drills NO.1 and No.2 at Dongliuhe Village on the hanging and foot walls ofXiadian fault allow us to quantitatively reconstruct the differential sedimentary history and vertical dislocation process on the hanging and foot walls of the fault since 26 ka BP and to set upa tectono-stratigraphic indicators for identifying paleoearthquakes.On this basis,taking theaccumulative vertical displacement of both sides of a fault to be a quantitative constraint,thestate before an abrupt dislocation in surface-rupturing earthquake can be reconstructed(de-ducting the later coseismic vertical displacement),then 11 surface-rupturing paleoseismic even-ts can be identified.A close correlation between recurrence behavior of | Xu Xiwei, Ji Fengju, Yu Guihua, Chen Wenbin, and Wang FengInstitute of Geology, CSB, Beijing 100029, ChinaJiang WaliInstitute of Crustal Dynamics, CSB, Beijing 100085, China | 2000 | Earthquake Research in China2000，14，4： | 0 |
| 18 | Identification and validation of stable quantitative trait loci for yield component traits in wheat显示文摘Grain weight and grain number are important yield component traits in wheat and identification of underlying genetic loci is helpful for improving yield.Here,we identified eight stable quantitative trait loci(QTL)for yield component traits,including five loci for thousand grain weight(TGW)and three for grain number per spike(GNS)in a recombinant inbred line population derived from cross Yangxiaomai/Zhongyou 9507 across four environments.Since grain size is a major determinant of grain weight,we also mapped QTL for grain length(GL)and grain width(GW).QTGW.caas-2D,QTGW.caas-3B,QTGW.caas-5A and QTGW.caas-7A.2 for TGW co-located with those for grain size.QTGW.caas-2D also had a consistent genetic position with QGNS.caas-2D,suggesting that the pleiotropic locus is a modulator of trade-off effect between TGW and GNS.Sequencing and linkage mapping showed that TaGL3-5A and WAPO-A1 were candidate genes of QTGW.caas-5A and QTGW.caas-7A.2,respectively.We developed Kompetitive allele specific PCR(KASP)markers linked with the stable QTL for yield component traits and validated their genetic effects in a diverse panel of wheat cultivars from the Huang-Huai River Valley region.KASP-based genotyping analysis further revealed that the superior alleles of all stable QTL for TGW but not GNS were subject to positive selection,indicating that yield improvement in the region largely depends on increased TGW.Comparative analyses with previous studies showed that most of the QTL could be detected in different genetic backgrounds,and QTGW.caas-7A.1 is likely a new QTL.These findings provide not only valuable genetic information for yield improvement but also useful tools for marker-assisted selection. | Lingli Li Yingjie Bian Yan Dong Jie Song Dan Liu Jianqi Zeng Fengju Wang Yong Zhang Zhonghu He Xianchun Xia Yan Zhang Shuanghe Cao | 2023 | The Crop Journal2023，11，2： | 0 |
| 19 | Postoperative changes in corneal epithelial and stromal thickness profiles after SMILE in high myopic eyes显示文摘Background:To observe changes in the epithelial and stromal thickness after small incision refractive lenticule extraction(SMILE)and investigate their relationship with the different refractive error.Methods:One hundred and eighty eyes of 90 patients with a manifest refraction spherical equivalent(MRSE)of-6.36±1.53 diopters(D)were included.The eyes were assigned to the moderate myopic group(MRSE-3.00 to-6.00 D),high myopic group(MRSE-6.00 to-8.00 D)and super-high myopic group(MRSE above-8.00 D).The spectral-domain optical coherence tomography(SD-OCT)measured corneal and epithelial thickness in 17 zones preoperatively and 1,3,and 6 months postoperatively.Stromal thickness was calculated by subtracting the epithelial thickness from the total corneal thickness.The observed changes were correlated with the degree of myopia corrected.Results:MRSE showed significant differences between 3 and 6 months in the super-high myopic group(P=0.024).At 6 months,a statistically significant epithelial thickness increase was observed in the central zone(7.18%for moderate,10.23%for high,and 13.76%for super-high myopia,P<0.05 for all groups).The peripheral thickness decreased between 3 and 6 months in the high myopia and super-high myopia groups(P<0.05,respectively).A positive correlation between MRSE corrected and the postoperative epithelial thickening was observed in the central(r2=0.551,P<0.05).Compared to 1 month values,the central stromal thickness showed a decrease(3.2±4.5μm)at 3 months and an increase(4.4±4.9μm)at 6 months.The stroma thickened in moderate and high myopic groups but the thickness reduction were in super-high myopia group at 6 months paracentrally and peripherally.Conclusions:Significant thickness changes in the epithelium and stroma were detected during the 6 months after SMILE.Preliminary results suggest that epithelial and stromal thickness profile changes after SMILE may have an impact on the refractive outcome in the long-term postoperative period,especially in super-higher degrees of myopia. | Dan Wang Ning Guo Yu Li Yan Zheng Fengju Zhang | 2021 | Annals of Eye Science2021，，1： | 0 |
| 20 | Development and evaluation of the screening performance of a low-cost high-risk screening strategy for breast cancer显示文摘Objective:To develop and evaluate the screening performance of a low-cost high-risk screening strategy for breast cancer in low resource areas.Methods:Based on the Multi-modality Independent Screening Trial,6 questionnaire-based risk factors of breast cancer(age at menarche,age at menopause,age at first live birth,oral contraceptive,obesity,family history of breast cancer)were used to determine the women with high risk of breast cancer.The screening performance of clinical breast examination(CBE),breast ultrasonography(BUS),and mammography(MAM)were calculated and compared to determine the optimal screening method for these high risk women.Results:A total of 94 breast cancers were detected among 31,720 asymptomatic Chinese women aged 45–65 years.Due to significantly higher detection rates(DRs)and suitable coverage of the population,high risk women were defined as those with any of 6 risk factors.Among high risk women,the DR for BUS[3.09/1,000(33/10,694)]was similar to that for MAM[3.18/1,000(34/10,696)],while it was significantly higher than that for the CBE[1.73/1,000(19/10,959),P=0.002].Compared with MAM,BUS showed significantly higher specificity[98.64%(10,501/10,646)vs.98.06%(10,443/10,650),P=0.001],but no significant differences in sensitivity[68.75%(33/48)vs.73.91%(34/46)],positive prediction values[18.54%(33/178)vs.14.11%(34/241)],and negative prediction values[99.86%(10,501/10,516)vs.99.89%(10,443/10,455)].Further analyses showed no significant difference in the percentages of early stage breast cancer[53.57%(15/28)vs.50.00%(15/30)],lymph node involvement[22.73%(5/22)vs.28.00%(7/25)],and tumor size≥2 cm[37.04%(10/27)vs.29.03%(9/31)]between BUS and MAM.Subgroup analyses stratified by breast densities or age at enrollment showed similar results.Conclusions:The low-cost high-risk screening strategy based on 6 questionnaire-based risk factors was an easy-to-use method to identify women with high risk of breast cancer.Moreover,BUS and MAM had comparable screening performances among high risk women. | Yubei Huang Huan Wang Zhangyan Lyu Hongji Dai Peifang Liu Ying Zhu Fengju Song Kexin Chen | 2022 | Cancer Biology & Medicine2022，19，9： | 0 |
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