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| 1 | Ileoscopy in patients with ileocolonic tuberculosis显示文摘AIM: To study the role of retrograde terminal ileoscopy in patients suspected to have ileocolonic tuberculosis. METHODS: A retrospective analysis was performed for patients undergoing colonoscopy for suspected ileocolonic tuberculosis between January 2000 and June 2004, in whom retrograde ileoscopy had been performed. Only patients diagnosed with tuberculosis on the basis of histological findings of either a caseating granuloma or those having non-caseating granuloma or a collection of epithelioid cells at a minimum of one endoscopic lesion (either in the colon or the terminal ileum) on histology with good responses to conventional anti-tuberculous drugs were enrolled for the study. RESULTS: Fifty-three patients were included. The terminal ileum was involved in only 11 patients. Eight of these patients had involvement of the cecum too. Two patients had ileal lesions without cecal involvement; however, lesions were noted in the ascending colon. In one patient the whole colon was normal and only the terminal ileum showed nodularity and ulceration. Histological examination of the ileal biopsies obtained from the ileal lesions showed noncaseating granulomas in five, collection of epithelioid cells in four and nonspecific histology in two patients. Mucosal biopsies obtained from the lesion in the terminal ileum, in the patient in whom mucosal abnormality was observed to be confined to the ileum, showed noncaseating granulomas. In two other patients the ileal biopsies alone showed histological evidence of tuberculosis with biopsies from the colonic lesions showing non-specific inflammatory changes only. CONCLUSION: Retrograde ileoscopy should be performed in all patients undergoing colonoscopy for suspected ileocolonic tuberculosis. In some patients only the terminal ileum may be involved and histological examination may reveal evidence of tuberculosis only from the lesions in the terminal ileum. This approach would lead to additional lesions being picked up andincreasing the chances of well-timed diagnosis of tuberculosis. | SP Misra Vatsala Misra Manisha Dwivedi | 2007 | World Journal of Gastroenterology2007,13,11: | 16 |
| 2 | Helicobacter pylori and gastric cancer: Indian enigma显示文摘Helicobacter pylori(H. pylori) is a gram negative microaerophilic bacterium which resides in the mucous linings of the stomach. It has been implicated in the causation of various gastric disorders including gastric cancer. The geographical distribution and etiology of gastric cancer differ widely in different geographical regions and H. pylori, despite being labeled as a grade Ⅰ carcinogen, has not been found to be associated with gastric cancer in many areas. Studies in Asian countries such as Thailand, India, Bangladesh, Pakistan, Iran, Saudi Arabian countries, Israel and Malaysia, have reported a high frequency of H. pylori infection co-existing with a low incidence of gastric cancer. In India, a difference in the prevalence of H. pylori infection and gastric cancer has been noted even in different regions of the country leading to a puzzle when attempting to find the causes of these variations. This puzzle of H. pylori distribution and gastric cancer epidemiology is known as the Indian enigma. In this review we have attempted to explain the Indian enigma using evidence from various Indian studies and from around the globe. This review covers aspects of epidemiology, the various biological strains present in different parts of the country and within individuals, the status of different H. pylori-related diseases and the molecular pathogenesis of the bacterium. | Vatsala Misra Renu Pandey Sri Prakash Misra Manisha Dwivedi | 2014 | World Journal of Gastroenterology2014,20,6: | 6 |
| 3 | Carcinogenic Helicobacter pylori in gastric pre-cancer and cancer lesions: Association with tobacco-chewing显示文摘AIM:To investigate the low gastric cancer incidence rate relative to the highly prevalent Helicobacter pylori(H.pylori)infection;data relevant to H.pylori infection during gastric carcinogenesis in Indian patients is currently lacking.METHODS:The present study examines the prevalence of H.pylori infection in DNA derived from 156endoscopic gastric biopsies of different disease groups that represent gastric pre-cancer[intestinal metaplasia(n=15),dysplasia(n=15)],cancer[diffuse adenocarcinoma(n=44),intestinal adenocarcinoma(n=21)],and symptomatic but histopathologically-normal controls(n=61).This was done by generic ureC polymerase chain reaction(PCR)and cagA-specific PCR that could specifically identify the carcinogenic H.pylori strain.RESULTS:Our analysis showed the presence of H.pylori infection in 61%of symptomatic histopathologically-normal individuals,however only 34%of control tissues were harboring the cagA+H.pylori strain.A similar proportion of H.pylori infection(52%)and cagA(26%)positivity was observed in the tumor tissue of the gastric cancer group.In comparison,H.pylori infection(90%)and cagA positivity(73%)were the highest in gastric pre-cancer lesions.In relation to tobacco and alcohol abuse,H.pylori infection showed an association with tobacco chewing,whereas we did not observe any association between tobacco smoking or alcohol abuse with prevalence of H.pylori infection in the tissue of any of the patient groups studied.CONCLUSION:High incidence of H.pylori infection and carcinogenic cagA positive strain in pre-cancer lesions during gastric carcinogenesis may be | Arvind Pandey Satyendra Chandra Tripathi Sutapa Mahata Kanchan Vishnoi Shirish Shukla Sri Prakash Misra Vatsala Misra Suresh Hedau Ravi Mehrotra Manisha DwivediZ Alok C Bharti | 2014 | World Journal of Gastroenterology2014,20,22: | 4 |
| 4 | Ileocecal masses in patients with amebic liver abscess:Etiology and management显示文摘瞄准:与阿米巴的肝脓肿在病人估计回盲肠质量的原因。方法:有阿米巴的肝脓肿和回盲肠质量的病人被结肠镜检查和活体检视材料的组织学的检查在结肠镜检查期间从损害跟随的提高对比的 CT 扫描小心地检查并且调查。结果:回盲肠群众与阿米巴的肝脓肿在十七个病人被发现。团的原因是在 14 个病人,的阿米巴瘤在在 1 个病人的盲肠的 2 个病人和腺癌的盲肠的肺结核。结肠的溃疡在中的五个被注意六(83%) 有在表示的活跃腹泻的病人。在所有这些病人的回盲肠团是阿米巴瘤。溃疡被看见在仅仅之一 11 (9%) 没有腹泻的病人。差别来自有腹泻(P< 0.005 ) 的组是统计上重要的。结论:回盲肠质量不是与阿米巴的肝脓肿的在病人的不平常的发现。尽管,回盲肠团由于在大多数情况中的阿米巴瘤形成,这是在所有病人的案例,这不应该被假定。结肠镜检查和目标活体检视的组织学的检查是强制的避免错过更不祥的损害。 | Sri Prakash Misra Vatsala Misra Marisha Dwivedi | 2006 | World Journal of Gastroenterology2006,12,12: | 3 |
| 5 | Berberine and Curcumin Target Survivin and STAT3 in Gastric Cancer Cells and Synergize Actions of Standard Chemotherapeutic 5-Fluorouracil显示文摘 | Arvind Pandey Kanchan Vishnoi Sutapa Mahata Satyendra Chandra Tripathi Sri Prakash Misra Vatsala Misra Ravi Mehrotra Manisha Dwivedi Alok C. Bharti | 2015 | Nutrition and Cancer2015,,8: | 2 |
| 6 | Analysis of Compressibility of Sensitive Soils显示文摘 | T. S. Nagaraj B. R. S. Murthy A. Vatsala R. C. Joshi | 1990 | Journal of Geotechnical Engineering1990,,1: | 2 |
| 7 | Basic theory of fractional differential equations显示文摘 | Lakshmikantham V Vatsala A S | 2008 | NONLINEAR ANALYSIS-THEORY METHODS & APPLICATIONS2008,69,8: | 1 |
| 8 | Analysis of compressibility of sensitive soils显示文摘 | NAGARAJ T S SRINIVASA MURTHY B R VATSALA A | 1990 | Journal of Geoteehnieal Engineering1990,116,: | 1 |
| 9 | Method of quasi-upper and lower solutions in abstract cones 显示文摘 | Lakshmikantham V Leela S Vatsala A S | 1982 | Nonlinear Anal1982,,6: | 1 |
| 10 | Elastoplastic model for cemented soils显示文摘 | VATSALA A NOVA R SRINIVASA MURTHY B R | 2001 | Journalof Geotechnical and Geoenvironmental Engineering2001,127,8: | 1 |
| 11 | Method of quasi-upper and lower solutions in abstract cones显示文摘 | LAKSHM I V LEELA S VATSALA A S | 1982 | Nonlinear Anal1982,,6: | 1 |
| 12 | Theory of fractional differential inequalities and applications 显示文摘 | Lakshmikantham V Vatsala A S | 2007 | Commun Appl Anal2007,11,: | 1 |
| 13 | Differential inequalities with initial time difference and applications显示文摘 | Lakshmikantham V Vatsala A S | 1999 | J Inequal Appl1999,3,3: | 1 |
| 14 | Basic theory of fractional differential equations 显示文摘 | Lakshmikantham V Vatsala A S | 2008 | Nonlinear Anal2008,69,: | 1 |
| 15 | C-phycocyanin from Spirulina fussiformis exposed to blue light demonstrates higher efficacy of in vitro antioxidant activity显示文摘 | MADHYASTHA H K SIVASHANKARI S VATSALA T M | 2009 | Biochemical Engineering Journal2009,43,: | 1 |
| 16 | Properties of an extracellular amylase purified from a Bacillus species显示文摘 | VATSALA M KAVITHA R | 2001 | World Microbiol Biotechnol2001,17,8: | 1 |
| 17 | Elastoplastic model for cemented soils显示文摘 | Vatsala A Nova R Srinivasa Murthy B R | 2001 | Journal of Geotechnical and Geoenvironmental Engineering2001,,8: | 1 |
| 18 | Elastoplastic model for cemented soils 显示文摘 | Vatsala A Nova R Murthy B R S | 2001 | Journal of Geotechnieal and Geoenvironmental Engineering2001,127,8: | 1 |
| 19 | Basic Theory of Fractional Differential Equations 显示文摘 | Lakshmikantham V Vatsala A S | 2008 | Nonlinear Anal TMA2008,69,8: | 1 |
| 20 | Basic theory of fractional differential equations显示文摘 | Lashmikantham V Vatsala A S | 2008 | Nonlinear Anal TMA2008,69,8: | 1 |