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6篇 您的检索式:作者名="Suresh Hedau"
    题名 作者 年代 出处 被引量
1Carcinogenic Helicobacter pylori in gastric pre-cancer and cancer lesions: Association with tobacco-chewing显示文摘AIM:To investigate the low gastric cancer incidence rate relative to the highly prevalent Helicobacter pylori(H.pylori)infection;data relevant to H.pylori infection during gastric carcinogenesis in Indian patients is currently lacking.METHODS:The present study examines the prevalence of H.pylori infection in DNA derived from 156endoscopic gastric biopsies of different disease groups that represent gastric pre-cancer[intestinal metaplasia(n=15),dysplasia(n=15)],cancer[diffuse adenocarcinoma(n=44),intestinal adenocarcinoma(n=21)],and symptomatic but histopathologically-normal controls(n=61).This was done by generic ureC polymerase chain reaction(PCR)and cagA-specific PCR that could specifically identify the carcinogenic H.pylori strain.RESULTS:Our analysis showed the presence of H.pylori infection in 61%of symptomatic histopathologically-normal individuals,however only 34%of control tissues were harboring the cagA+H.pylori strain.A similar proportion of H.pylori infection(52%)and cagA(26%)positivity was observed in the tumor tissue of the gastric cancer group.In comparison,H.pylori infection(90%)and cagA positivity(73%)were the highest in gastric pre-cancer lesions.In relation to tobacco and alcohol abuse,H.pylori infection showed an association with tobacco chewing,whereas we did not observe any association between tobacco smoking or alcohol abuse with prevalence of H.pylori infection in the tissue of any of the patient groups studied.CONCLUSION:High incidence of H.pylori infection and carcinogenic cagA positive strain in pre-cancer lesions during gastric carcinogenesis may beArvind Pandey Satyendra Chandra Tripathi Sutapa Mahata Kanchan Vishnoi Shirish Shukla Sri Prakash Misra Vatsala Misra Suresh Hedau Ravi Mehrotra Manisha DwivediZ Alok C Bharti 2014World Journal of Gastroenterology2014,20,22:4
2p53 gene mutation and human papillomavirus(HPV) infection in eso-phageal carcinoma from three different endemic geographic regions of India 显示文摘Sanjay Katiyar Suresh Hedau Neeraj Jain 2005Cancer Letters2005,,218:1
3p53 gene mutation and human papillomavirus (HPV) infection in esophageal carcinoma from three different endemic geographic regions of India显示文摘Sanjay Katiyar Suresh Hedau Neeraj Jain 2005Cancer Letters2005,,218:1
4p53 gene mutation and human papillomavirus (HPV) infection in esophageal carcinoma from three different endemic geographic regions of India显示文摘Sanjay Katiyat Suresh Hedau Neeraj Jain 2005Cancer Letters2005,218,:1
5p53 gene mutation and human papillomavirus (HPV) infection in esophageal carcinoma from three different endemic geographic regions of India显示文摘Sanjay Katiyat Suresh Hedau Neeraj Jain 2005Cancer Letters2005,218,:1
6p53 gene mutation and human pap illomavirus(HPV) infection in esophageal carcinoma from three different endemic geographic regions of India 显示文摘Sanjay Katiyar Suresh Hedau Neeraj Jain 2005Cancer Letters2005,218,:1
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