|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A phase Ⅰ study of a new polyamine biosynthesis inhibitor,SAM486A,in cancer patients with solid tumours显示文摘 | Paridaens R Uges DR Barbet N | 2000 | Br J Cancer2000，83，5： | 1 |
| 2 | Stabili- ty of the nev anticattcer platinum analogue 1,2-diaminomethyl- cyclobutane-platinum( I1 )-lactate ( lobaplatin; D19466 ) in intra- venous solutions显示文摘 | GUCHELAAR HJ UGES DR AULENBACHER P | 1992 | Pharm Res1992，9，6： | 1 |
| 3 | Stabili- ty of the new anticaneer platinum analogue 1,2-diaminomethyl- cyclobutane-platinum( 1] )-lactate ( lobaplatin; D19466 ) in intra- venous solutions显示文摘 | GUCHELAAR HJ UGES DR AULENBACHER P | 1992 | Pharm Res1992，9，6： | 1 |
| 4 | Pharmacokineticsof high-dose oral and intravenous dexamethasone显示文摘 | Tóth GG Kloosterman C Uges DR | 1999 | Ther Drug Monit1999，21，： | 1 |
| 5 | Limited sampling strategies for thera peutie drug monitoring of linezolid in patients with multidrug resistant tuberculosis显示文摘 | Alffenaar JW Kosterink JG van Altena R van der Werf TS Uges DR Proost JH | 2010 | Ther Drug Monit2010，32，1： | 1 |
| 6 | Robust, high-throughput LC- MS/MS method for therapeutic drug monitoring of cyclosporine, tacrolimus, everolimus, and sirolimus in whole blood显示文摘 | Koster RA Dijkers EC Uges DR | 2009 | Ther Drug Monit2009，31，1： | 1 |
| 7 | Surface rough- ness, porosity and wettability of gentamicin-loaded bone cements and their antibiotic release 显示文摘 | van de Belt H Neut D Uges DR | 2000 | Biomaterials2000，21，19： | 1 |
| 8 | Increasing the dosage of vincristine: a clinical and pharmacokinetic study of continuous-infusion vincristine in children with central nervous system tumors显示文摘BACKGROUND: Vincristine (VCR) is widely used to treat patients with malignant disease; among the patients treated with VCR are children with brain tumors. In vitro studies have demonstrated that the cytotoxic activity of VCR is related to both extracellular concentration and duration of exposure. The attainment of higher plasma concentrations by injecting larger bolus doses of VCR has been limited by concerns about neurotoxicity. One possible alternative strategy for enhancing the antitumor efficacy of VCR involves prolonging the duration of in vivo exposure. Therefore, the authors explored the neurotoxicity and pharmacokinetics of VCR administered via a 96hour continuous infusion after administration of a conventional bolus dose in a pediatric population. METHODS: The current study included 16 patients, 11 of whom were males. The median age of the study population was 4. 8 years (range, 1.7-15. 8 years). | Kellie SJ Koopmans P Earl J Nath C Roebuck D Uges DR De Graaf SS | 2004 | 中国神经肿瘤杂志2004，2，2： | 1 |
| 9 | Pharmacokinetics of highdose oral and intravenous dexamethasone显示文摘 | Toth GG Kloosteman C Uges DR | 1999 | Ther Drug Monit1999，21，5： | 1 |
| 10 | Influence of vascular oxidative stress and inflammation on the development and progression of atherosclerosis 显示文摘 | Bronas UG Dengel DR | 2010 | Am J Lifestyle Med2010，4，6： | 1 |
| 11 | Robust,High-Throughput LC-MS/MS method for therapeutic drug monitoring of cyclosporine,tacrolimus,everolimus,and sirolimus in whole blood显示文摘 | KOSTER RA DIJKERS EC UGES DR | 2009 | Ther Drug Monit2009，31，1： | 1 |
| 12 | Surface roughness, porosity and wettability of gentamicin - loaded bone cements and their antibi- otic release 显示文摘 | van de Belt H Neut D Uges DR | 2000 | Biomaterials2000，19，： | 1 |
| 13 | Effects of diltiazem oncation transport across erythrocyte membranes of hypertensive hu-mans显示文摘 | Khalil MF Samant DR Gadqil UG | 1987 | Hypertension1987，9，1： | 1 |
| 14 | Simultaneous quantitativedetermination of the major phase ⅠandⅡ metabolism of ibuprofen in biological fluids by high-performance liquid chromatography on dynamically modified silica显示文摘 | Kepp DR Sidelmann UG Tjornelund J | 1997 | J Chromatogr B Biomed Sci Appl1997，696，2： | 1 |
| 15 | Phase Ⅰ and pharmaco-kinetic study of the topoisomerase Ⅱ catalytic inhibitor fostriecin 显示文摘 | de Jong RS Mulder NH Uges DR | 1999 | Br J Cancer1999，79，56： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员