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| 1 | Feasibility and safety of endoscopic submucosal dissection for lower rectal tumors with hemorrhoids显示文摘AIM: To evaluate the feasibility and safety of endoscopic submucosal dissection(ESD) for lower rectal lesions with hemorrhoids.METHODS: The outcome of ESD for 23 lesions with hemorrhoids(hemorrhoid group) was compared with that of 48 lesions without hemorrhoids extending to the dentate line(non-hemorrhoid group) during the same study period. RESULTS: Median operation times(ranges) in the hemorrhoid and non-hemorrhoid groups were 121(51-390) and 130(28-540) min. The en bloc resection rate and the curative resection rate in the hemorrhoid group were 96% and 83%, and they were 100% and 90% in the non-hemorrhoid group, respectively. In terms of adverse events, perforation and postoperative bleeding did not occur in both groups. In terms of the clinical course of hemorrhoids after ESD, the rate of complete recovery of hemorrhoids after ESD in lesions with resection of more than 90% was significantly higher than that in lesions with resection of less than 90%.CONCLUSION: ESD on lower rectal lesions with hemorrhoids could be performed safely, similarly to that on rectal lesions extending to the dentate line without hemorrhoids. In addition, all hemorrhoids after ESD improved to various degrees, depending on the resection range. | Shinwa Tanaka Takashi Toyonaga Yoshinori Morita Namiko Hoshi Tsukasa Ishida Yoshiko Ohara Tetsuya Yoshizaki Fumiaki Kawara Eiji Umegaki Takeshi Azuma | 2016 | World Journal of Gastroenterology2016，22，27： | 6 |
| 2 | Gastric plexiform fibromyxoma resected by endoscopic submucosal dissection after observation of chronological changes:A case report显示文摘A 66-year-old man was diagnosed with a gastric submucosal tumor. Endoscopic ultrasound(EUS) revealed an iso/hypoechoic mass in the third layer. No malignant cells were detected in a histological examination. Yearly follow-up endoscopy and EUS showed the slow growth of the tumor. Endoscopic submucosal dissection(ESD) was performed and a glistening tumor was resected. The lesion showed a multinodular plexiform growth pattern consisting of spindle cells with an abundant fibromyxoid stroma that was rich in small vessels. The tumor was diagnosed as plexiform fibromyxoma(PF) by immunohistochemistry. Although difficulties are associated with reaching a diagnosis preoperatively, chronological changes on EUS may contribute to the diagnosis of PF. ESD may also be useful in the diagnosis and treatment of PF. | Fumiaki Kawara Shinwa Tanaka Takashi Yamasaki Yoshinori Morita Yoshiko Ohara Yoshihiro Okabe Namiko Hoshi Takashi Toyonaga Eiji Umegaki Hiroshi Yokozaki Takanori Hirose Takeshi Azuma | 2017 | World Journal of Gastrointestinal Oncology2017，9，6： | 3 |
| 3 | Retrospective study of technical aspects and complications of endoscopic submucosal dissection for laterally spreading tumors of the colorectum显示文摘 | T. Toyonaga M. Man-i T. Fujita J. East E. Nishino W. Ono Y. Morita T. Sanuki M. Yoshida H. Kutsumi H. Inokuchi T. Azuma | 2010 | Endoscopy2010，，09： | 3 |
| 4 | Esophageal diverticulum exposed during endoscopic submucosal dissection of superficial cancer显示文摘Endoscopic submucosal dissection(ESD) is now widely accepted as a strategy to treat superficial esophageal neoplasms.The rate of adverse events,such as perforation,has been decreasing with the improvement of devices and techniques.In this paper,we report a case of esophageal cancer that had a diverticulum under cancerous epithelium.The diverticulum was not detected during preoperative examination,and led to perforation during the ESD procedure.Our case shows that,although rare,some diverticula can exist underneath the mucosal surface without obvious depression.If there is any sign of hidden diverticula during ESD,surgeons should proceed with caution or,depending on the case,the procedure should be discontinued to avoid adverse events. | Shinwa Tanaka Takashi Toyonaga Yoshiko Ohara Tetsuya Yoshizaki Fumiaki Kawara Tsukasa Ishida Namiko Hoshi Yoshinori Morita Takeshi Azuma | 2015 | World Journal of Gastroenterology2015，21，10： | 2 |
| 5 | Optimum Treatment Strategy for Superficial Esophageal Cancer: Endoscopic Mucosal Resection versus Radical Esophagectomy显示文摘 | Hiromasa Fujita Susumu Sueyoshi Hideaki Yamana Koji Shinozaki Uhi Toh Yuichi Tanaka Takashi Mine Masahiro Kubota Kazuo Shirouzu Atsushi Toyonaga Hiroshi Harada Sigeki Ban Masahide Watanabe Yukihiko Toda Emi Tabuchi Naofumi Hayabuchi Hiroki Inutsuka | 2001 | World Journal of Surgery2001，，4： | 2 |
| 6 | 数码时代的雕塑叛逆儿——名和晃平显示文摘一头透明的巨鹿,静静地伫立在宽阔的空间。这头在空气的轮廓中闪闪发光的灵性动物.甚至不存在——看不到皮毛.嗅不到味道.没有任何可视的色彩。它在空间中突然凝结而成,也许会忽然消散而逝。泉水泡般清亮的水晶密布在“鹿”的全身.观者记忆中“鹿”的形状被完全覆盖;来自空间的自然光亮在水晶的折射中熠熠烁烁,通过鹿透亮的表皮.四周的景像若隐若现。 | 方莉 名和晃平 Seiji Toyonaga | 2010 | 建筑知识2010，，1： | 2 |
| 7 | Postoperative urinary retention after surgery for benign anorectal disease: potential risk factors and strategy for prevention显示文摘 | Takayuki Toyonaga Makoto Matsushima Nobuhito Sogawa Song Feng Jiang Naomi Matsumura Yasuhiro Shimojima Yoshiaki Tanaka Kazunori Suzuki Junnichi Masuda Masao Tanaka | 2006 | International Journal of Colorectal Disease2006，，7： | 2 |
| 8 | Endoscopic submucosal dissection for early gastric cancer in anastomosis site after distal gastrectomy显示文摘 | Shinwa Tanaka Takashi Toyonaga Yoshinori Morita Tsuyoshi Fujita Tetsuya Yoshizaki Fumiaki Kawara Chika Wakahara Daisuke Obata Aya Sakai Tsukasa Ishida Nobunao Ikehara Takeshi Azuma | 2014 | Gastric Cancer2014，，2： | 2 |
| 9 | Value of Doppler ultrasound parameters of portal vein and hepatic artery in the diagnosis of cirrhosis and portal hypertension 显示文摘 | Iwao T Toyonaga A Oho K | 1997 | Am J Gastroenterol1997，92，6： | 1 |
| 10 | Characterization ofmicroglia induced from mouse embryonic stem cells andtheir migration into the brain parenchyma 显示文摘 | Tsuchiya T Park KC Toyonaga S | 2005 | J Neuroim-munol2005，160，12： | 1 |
| 11 | A case of successful transcatheter splenic arterial embolization (TSAE)in traumatic injury of the spleen显示文摘 | Sakai T Hirai K Toyonaga A etal | 1986 | Rinsho Hoshasen1986，31，1： | 1 |
| 12 | Role of the upstream region containing an intrinsic DNA curvature in the negative regulation of the phospholipase C gene of Clostridium perfringens 显示文摘 | Toyonaga T Matsushita O Katayama S I | 1992 | Microbiol Immunol1992，36，： | 1 |
| 13 | Insulin down-regulates resistin mRNA through the synthesis of protein(s) that could accelerate the degradation of resistin mRNA in 3T3-L1 adipocytes显示文摘 | J. Kawashima K. Tsuruzoe H. Motoshima A. Shirakami K. Sakai Y. Hirashima T. Toyonaga E. Araki MD PhD | 2003 | Diabetologia2003，，2： | 1 |
| 14 | Blockade of constitutively activated Janus kinase/signal transducer and activator of transeription pathway inhibits growth of human pancreatic cancer显示文摘 | Toyonaga T Nakano K Nagano M | 2003 | Cancer Lett2003，201，1： | 1 |
| 15 | Completion radical surgery after cholecystectomy for accidentally undiagnosed gallbladder carcinoma显示文摘 | Toyonaga T Chijiiwa K Nakano K | 2003 | World J Surg2003，27，3： | 1 |
| 16 | Postoperative urinary retention after surgery for benign anorectal disease: potential risk factors and strategy for prevention显示文摘 | TOYONAGA T MATSUSHIMA M SOGAWA N | 2006 | Int J Colorectal Dis2006，21，7： | 1 |
| 17 | Circulating vascular endothelial growth factor in patients with colorectal cancer显示文摘 | Fujisaki K Mitsuyama K Toyonaga A | 1998 | Am J Gastroenterol1998，93，2： | 1 |
| 18 | Value of Doppler Ultrasound Parameters of Portal Vein and Hepatic Artery in the Diagnosis of Cirrhosis and Portal Hyper-tension显示文摘 | Iwao T Toyonaga A Oho K | 1997 | Am J Gastroenterol1997，92，： | 1 |
| 19 | Colonic mueosal inter- leukin - 6 in inflammatory bowel disease 显示文摘 | Mitsuyama K Sasaki E Toyonaga A | 1991 | Digestion1991，50，： | 1 |
| 20 | Significant associ- ations of metabolie syndrome and its components with si- lent lacunar infarction in middle aged subjects 显示文摘 | Park K Yasuda N Toyonaga S | 2008 | J Neu- rol Neurosurg Psychiatry2008，79，6： | 1 |
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