2篇
您的检索式：作者名="Tate Shannon"
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| 1 | Effects of SDF-1–CXCR4 signaling on microRNA expression and tumorigenesis in estrogen receptor-alpha (ER-α)-positive breast cancer cells显示文摘 | Lyndsay V. Rhodes Melyssa R. Bratton Yun Zhu Syreeta L. Tilghman Shannon E. Muir Virgilio A. Salvo Chandra R. Tate Steven Elliott Kenneth P. Nephew Bridgette M. Collins-Burow Matthew E. Burow | 2011 | Experimental Cell Research2011，，18： | 1 |
| 2 | Development of a modular, biocompatible thiolated gelatin microparticle platform for drug delivery and tissue engineering applications显示文摘The field of biomaterials has advanced significantly in the past decade.With the growing need for high-throughput manufacturing and screening,the need for modular materials that enable streamlined fabrication and analysis of tissue engineering and drug delivery schema has emerged.Microparticles are a powerful platform that have demonstrated promise in enabling these technologies without the need to modify a bulk scaffold.This building block paradigm of using microparticles within larger scaffolds to control cell ratios,growth factors and drug release holds promise.Gelatin microparticles(GMPs)are a well-established platform for cell,drug and growth factor delivery.One of the challenges in using GMPs though is the limited ability to modify the gelatin post-fabrication.In the present work,we hypothesized that by thiolating gelatin before microparticle formation,a versatile platform would be created that preserves the cytocompatibility of gelatin,while enabling post-fabrication modification.The thiols were not found to significantly impact the physicochemical properties of the microparticles.Moreover,the thiolated GMPs were demonstrated to be a biocompatible and robust platform for mesenchymal stem cell attachment.Additionally,the thiolated particles were able to be covalently modified with a maleimide-bearing fluorescent dye and a peptide,demonstrating their promise as a modular platform for tissue engineering and drug delivery applications. | Hannah A.Pearce Yu Seon Kim Emma Watson Kiana Bahrami Mollie M.Smoak Emily Y.Jiang Michael Elder Tate Shannon Antonios G.Mikos | 2021 | Regenerative Biomaterials2021，8，3： | 1 |
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