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1双对吻挤压与经典挤压技术治疗冠状动脉分叉病变的前瞻性、随机、多中心研究显示文摘目的比较双对吻挤压(DK crush)和经典挤压技术治疗冠状动脉分叉病变的临床效果。方法311例真性分叉病变患者随机分入DK crush组(n=155)和经典挤压组(n=156),随访时间8个月。一级及二级终点分别为主要心脏不良事件(MACE,包括心肌梗死、心原性死亡和靶病变血运重建)和血管直径再狭窄及晚期丢失。结果DK crush组糖尿病患者较多。经典挤压组及DK crush组最终对吻扩张(FKBI)成功率分别为76%和100%(P〈0.001)。DK crush术式的不足包括造影剂用量大(P=0.04)、球囊数量多(P〈0.01)、手术时间长(P〈0.001),但是对吻扩张不满意率显著减少(27.6%比6.3%,P〈0.01)。临床随访率为100%,冠状动脉造影随访率为82%。经典挤压组累计再狭窄率为32.3%,而DK crush组为20.3%(P=0.01),经典挤压组分支血管再狭窄率高(24.4%比12.3%,P=0.01),而两组间主干血管再狭窄率差异无统计学意义。经典挤压组术后8个月时的累计MACE发生率为24.4%(FKBI失败组为35.9%,FKBI成功组为19.7%),显著高于DK crush组(11.4%,P=0.02)。经典挤压组血栓栓塞率为3.2%(FKBI失败组为5.1%,FKBI成功组为1.7%),而DK crush组为1.3%(P〉0.05)。经典挤压组术后8个月时无靶病变血运重建生存率为75.4%(FKBI失败组为71.2%,FKBI成功组为77.6%),而DK crush组为89.5%(P=0.002)。结论DKcrush可能是治疗冠状动脉分又病变的较佳术式。陈绍良 张俊杰 叶飞 陈韵岱 吕树铮 Tan Huaycheem Tejas Patel Kawajiri Kenji Israel Tamari 单守杰 朱中生 林松 田乃亮 李晓波 刘志忠 Michael Lee 魏盟 徐亚伟 袁争白 钱均 孙学文 杨松 陈金国 何奔 Sumitsuji 2008中华心血管病杂志2008,36,2:5
2经皮切割球囊治疗支架内再狭窄:即刻效果和 6个月随访研究(英文)显示文摘目的 研究切割球囊对支架内再狭窄的即刻和 6个月内随访效果。方法 6 9例支架内再狭窄患者随机分配到切割球囊和普通球囊治疗组。切割球囊组 38例。球囊扩张前及扩张后即刻在定量冠状动脉造影和冠状动脉内超声下 ,测定相关参数。随访 6个月内临床改善及冠状动脉造影结果。研究终点包括出现心肌梗塞 ,需要冠状动脉搭桥或再介入治疗。结果 两组的手术成功率为 10 0 %。切割球囊组 1例患者扩张后在支架的远端出现夹层。平均随访 6 7± 2 3月。切割球囊组于术后 3和 6个月时的再狭窄率显著低于普通球囊组 (15 %VS 38%及 18%VS 4 3%,P均小于0 0 0 1)。扩张后即刻血管直径获得值在切割球囊组和普通球囊组分别为 1 72± 0 5 2mm和 1 15± 0 5 4mm ,而随访终点时切割球囊组的血管直径晚期丢失为 0 2 6± 0 0 5mm(3个月 )及 0 38± 0 0 6mm ,同时的普通球囊组丢失值为 0 78± 0 19mm(3个月 )及 0 89± 0 16mm。对于支架体部狭窄 ,普通球囊难以固定 ,扩张时移动明显 ,而切割球囊较易于固定 ,扩张时罕见移动。结论 切割球囊治疗支架内再狭窄效果可靠 ,安全 ,容易操作。再狭窄率低 ,手术费用相对易于患者接受 ,是一个较有前途的治疗手段。陈绍良 段宝祥 刘志忠 吴翔 魏福祥 钱学礼 叶飞 方五旺 胡作英 Isreal Tamari 陈淮沁 2002Chinese Medical Journal2002,,2:2
3Germination of chlorophyllous and achlomphyllous seeds of Salsola volkensii and Aellenia autrani显示文摘Negbi M Tamari B 1963Israel Journal of Botany1963,12,:1
4Consensus Paper-ICIS Expert Meeting Basel 2009 treatment milestones in immune thrombocytopenia显示文摘Tamary H Roganovic J Chitlur M 2010Annals of hematology2010,89,1:1
5Transplant for MDS: chal- lenges and emer-ging strategies 显示文摘Tamari R Castro-Malaspina H 2015Best Pract Res Clin Heamatol2015,28,1:1
6Inhibition of ethylene-induced cellular senescence symptoms by 1-methylcyclopropene, a new inhibitor of ethylene action显示文摘 Tamari G Sisler E C 1995Physiol Plant1995,94,:1
7Clinical results of endarterectomy of the right and left anterior descending coronary arteries 显示文摘Abraharnov D Tamaris M Guru V 1999J Card Surg1999,14,1:1
8Hepatic iron overload:quantitative MR imaging显示文摘Gomori J M Horev C Tamary H 0,,2:1
9Blockade of interleukin-6 receptor suppresses inflammatory reaction and facilitates functional re- covery following olfactory system injury 显示文摘Kobayashi M Tamari K Miyamura T 2013Neurosci Res2013,76,3:1
10Acceleration of wound healing with stem cell-derived growth factors显示文摘Tamari M Nishino Y Yamamoto N 2013Int J Oral Maxillofac Implants2013,28,6:1
11Effect of Spark Plasma Sintering on Densification and Mechanical Properties of Silicon Carbide显示文摘Tamari N T Tanaka K 1995Journal of Ceramic Society of Japan1995,103,7:1
12Fabrication of Silicon Carbide Ceramics Added with Boron and Carbon by Spark Plasma sintering and Their Mechanical Properties显示文摘Tamari N Kondoh I Tanaka T 2004Journal of the Japan Society of Powder Metallurgy2004,47,3:1
13CD40 ligand gen and Kawasaki disease显示文摘Onouchi Y Onoue S Tamari M 2004Eur J Hum Genet2004,12,12:1
14Germination of chlorphyllous and achlorphyllous seeds of Salssola volkensii and Aellenia outruni显示文摘Negbi M Tamari B 0,,:1
15Mixotrophic cultivation of Chlorella vulgaris and its potential application for the oil accumulation from non-sugar materials显示文摘TAMARYS HA WEI W ROGER R 0,,5:1
16Monocyte-derived microparticles and exosomes induce procoagulant and apoptotic effects on endothelial cells显示文摘Aharon A Tamari T Brenner B 2008Throm Haemost2008,100,5:1
17Seismic soil-structure interaction of cross sections of flexible underground structures subjected to soil liquefaction显示文摘TAMARI Y TOWHATA I 2003Soils and Foundations2003,43,2:1
18Commentary: a case for minimizing folate supplementation in clinical regimens with pemetrexed based on the marked sensitivity of the drug to folate availability显示文摘Chattopadhyay S Tamari R Min SH 2007Oncologist2007,12,7:1
19Improvement of mechanical strength of 8 mol% yttria-stabilized zirconia ceramics by spark-plasma sintering 显示文摘 KONDOH I TAMARI N 2002J Electrochem Soc2002,149,4:1
20Sugar-de- pendent gibberellin-induced Chalcone Synthase gene expression in Petunia Corollas显示文摘Moalem-Beno D Tamari G Leitner-Dagan Y 1997Plant Physiol1997,113,2:1
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