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| 1 | Celiac disease:Management of persistent symptoms in patients on a gluten-free diet显示文摘AIM:To investigate all patients referred to our center with non-responsive celiac disease (NRCD),to establish a cause for their continued symptoms.METHODS:We assessed all patients referred to our center with non-responsive celiac disease over an 18-mo period.These individuals were investigated to establish the eitiology of their continued symptoms.The patients were first seen in clinic where a thorough history and examination were performed with routine blood work including tissue transglutaminase antibody measurement.They were also referred to a specialist gastroenterology dietician to try to identift any lapses in the diet and sources of hidden gluten ingestion.A repeat small intestinal biopsy was also performed and compared to biopsies from the referring hospital where possible.Colonoscopy,lactulose hydrogen breath testing,pancreolauryl testing and computed tomography scan of the abdomen were undertaken if the symptoms persisted.Their clinical progress was followed over a minimum of 2 years.RESULTS:One hundred and twelve consecutive patients were referred with NRCD.Twelve were found not to have celiac disease (CD).Of the remaining 100 patients,45% were not adequately adhering to a strict gluten-free diet,with 24 (53%) found to be inadvertently ingesting gluten,and 21 (47%) admitting noncompliance.Microscopic colitis was diagnosed in 12% and small bowel bacterial overgrowth in 9%.Refractory CD was diagnosed in 9%.Three of these were diagnosed with intestinal lymphoma.After 2 years,78 patients remained well,eight had continuing symptoms,and four had died.CONCLUSION:In individuals with NRCD,a remediable cause can be found in 90%:with continued gluten ingestion as the leading cause.We propose an algorithm for investigation. | David H Dewar Suzanne C Donnelly Simon D McLaughlin Matthew W Johnson H Julia Ellis Paul J Ciclitira | 2012 | World Journal of Gastroenterology2012，18，12： | 2 |
| 2 | Homocysteine, 5, 10 methylenetetrahydrofolate reductase 677C>T polymorphism, nutrient intake, and incident cardiovascular disease in 24 968 initially healthy women显示文摘 | Robert YL Zee SM Suzanne C | 2007 | Clinical Chemistry2007，53，10： | 1 |
| 3 | Microparticles of poly (DL-lactic-co-glycolic acid)/poly (ethylene glycol) blends for controlled drug delivery 显示文摘 | ROBERT L C KAREN C K SUZANNE G E | 1997 | J Control Rel1997，48，： | 1 |
| 4 | Polymorphisms of thephosphodiesterase 4D, cAMP-Specific (PDE4D) gene and risk ofischemic stroke: A prospective, nested case-control evaluation 显示文摘 | Robert YLZ Victoria FIB Suzanne C | 2006 | Stroke2006，37，8： | 1 |
| 5 | Purification and assay methods for angiotensin-converting enzyme 显示文摘 | Qing C M Suzanne O | 1996 | J Chromatography1996，743，： | 1 |
| 6 | Cathepsin cysteine proteases in cardiovascular disease 显示文摘 | Suzanne L Kitty C Mat J | 2007 | FASEB J2007，21，12： | 1 |
| 7 | Preparedness needs assessment in a rural state:themes derived from public focus groups 显示文摘 | Amy C Elizabeth A Suzanne RH | 2006 | Biosecufity and Bioterrorism : Biodefense Strategy Practice and Science2006，4，4： | 1 |
| 8 | Microparticles of poly ( DL-lactic-co-glycolic acid )/poly ( ethylene glycol ) blends for controlled drug delivery 显示文摘 | Robert L Cleek Karen C Ting Suzanne G Eskin | 1997 | J Controlled Release1997，48，： | 1 |
| 9 | Follow-up study of the GIGYF2gene in French families with Parkinson’s disease显示文摘 | Suzanne L Christel C Ebba L | 2010 | Neurobiology ofAging2010，31，6： | 1 |
| 10 | A major role of the RecFOR pathway in DNA double strand break repair through ESDSA in Deinococcus radiodurans 显示文摘 | Esma B Pascale S Generieve C Suzanne S | 2010 | PLoS Genetics2010，6，1： | 1 |
| 11 | Evaluation and management of pain in dominant polycystic kidney disease 显示文摘 | Marie C Hogan Suzanne M | 2010 | Advance in Chronic Kidney Disease2010，17，3： | 1 |
| 12 | Survival of Escherichiacoli during long - term starvation : effects of aeration, NaC1, and the rpoS and osmC gene products显示文摘 | Conter A Gangneux C Suzanne M | 2001 | Research in Microbiology2001，152，1： | 1 |
| 13 | Quantifying preferential flow in soils:A review of different techniques显示文摘 | Suzanne E A Stéphanie R Allan J C | 2009 | Journal of Hydrology2009，378，12： | 1 |
| 14 | Retrospective cohort study evaluating the impact of intraperitoneal morcellation on outcomes of lo- calized uterine leiomyosareoma 显示文摘 | Suzanne G Barysauskas C Serrano C | 2014 | Cancer Month2014，120，20： | 1 |
| 15 | Polymorphism in the P-selectin and interleukin-4 genes as determinants of stroke: a populationbased,prospective genetic analysis'显示文摘 | Robert YL Nancy RC Suzanne C | 2004 | Human Molecular Genetics2004，13，4： | 1 |
| 16 | Effects of fermented milk supplement with pumpkin (Cucurbita moschata) on bone loss in Postmenopausal osteoporosis rat model显示文摘 | Suzanne C | | 0，，21： | 1 |
| 17 | Plague, a reemerging disease in Madagascar显示文摘 | Suzanne C Lala R Bruno R | 1998 | Emerg Infect Dis1998，4，1： | 1 |
| 18 | Survival of Escherichia coli during long - term starvation : effects of aeration, NaCl, and the rpoS and osmC gene products显示文摘 | Conter A Gangneux C Suzanne M | 2001 | Research in microbiology2001，152，1： | 1 |
| 19 | Bcl-2-regulated apoptosis : mechanism and therapeutic potential显示文摘 | Jerry MA Suzanne C | 2007 | C urr Opin Immun2007，19，5： | 1 |
| 20 | First clini- cal experience with a multiple region of interest registration and correction method in radiotherapy of head and neck cancer pations 显示文摘 | Stroom J C Suzanne van Beek Simon van Kranen | 2010 | Radiother Oncol2010，94，2： | 1 |
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