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| 1 | Mesenchymal stem cells over-expressing hepatocyte growth factor improve small-for-size liver grafts regeneration显示文摘 | Yu, Y. Yao, A. H. Chen, N. Pu, L. Y. Fan, Y. Lv, L. Sun, B. C. Li, G. Q. Wang, X. H. | 2007 | 南京医科大学学报(自然科学版)2007,27,10: | 45 |
| 2 | Schistosoma japonicum egg antigens stimulate CD4(+) CD25(+) T cells and modulate airway inflammation in a murine model of asthma显示文摘 | Yang, J. H. Zhao, J. Q. Yang, Y. F. Zhang, L. Yang, X. Zhu, X. Ji, M. J. Sun, N. X. Su,C. | 2007 | 南京医科大学学报(自然科学版)2007,27,4: | 25 |
| 3 | Aquaporin-4 deficiency down-regulates glutamate uptake and GLT-1 expression in astrocytes显示文摘 | Zeng, X. N. Sun, X. L. Gao, L. Fan, Y. Ding, J. H. Hu, G. | 2007 | 南京医科大学学报(自然科学版)2007,27,5: | 20 |
| 4 | K-ATP channel openers facilitate glutamate uptake by GluTs in rat primary cultured Astrocytes显示文摘Increasing evidence, including from our laboratory, has revealed that opening of ATP sensitive potassium channels(K-ATP channels) plays the neuronal protective roles both in vivo and in vitro. Thus K-ATP channel openers(KCOs) have been proposed as potential neuroprotectants. Our previous studies demonstrated that K-ATP channels could regulate glutamate uptake activity in PC12 cells as well as in synaptosomes of rats. Since glutamate transporters(GluTs) of astrocytes play crucial roles in glutamate uptake and KATP channels are also expressed in astrocytes, the present study showed whether and how KATP channels regulated the function of GluTs in primary cultured astrocytes. The results showed that nonselective KCO pinacidil, selective mitochondrial KCO diazoxide, novel, and blood-brain barrier permeable KCO iptakalim could enhance glutamate uptake, except for the sarcolemmal KCO P1075. Moreover pinacidil, diazoxide, and iptakalim reversed the inhibition of glutamate uptake induced by 1-methyl-4-phenylpyridinium(MPP+). These potentiated effects were completely abolished by mitochondrial K-ATP blocker 5-hydroxydecanoate. Furthermore, either diazoxide or iptakalim could inhibit MPP+-induced elevation of reactive oxygen species (ROS) and phosphorylation of protein kinases C(PKC). These findings are the first to demonstrate that activation of K-ATP channel, especially mitochondrial K-ATP channel, improves the function of GluTs in astrocytes due to reducing ROS production and downregulating PKC phosphorylation. Therefore, the present study not only reveals a novel pharmacological profile of KCOs as regulators of GluTs, but also provides a new strategy for neuroprotection. | Sun, X. L. Zeng, X. N. Zhou, F. Dai, C. P. Ding, J. H. Hu, G. Nanjing Med Univ,Dept Anat Histol & Pharmacol,Neuropharmacol Lab,Nanjing 210029,Jiangsu,Peoples R China. | 2008 | 南京医科大学学报(自然科学版)2008,28,6: | 7 |
| 5 | Direct observation of Pt nanocrystal coalescence induced by electron-excitation-enhanced van der Waals interactions显示文摘 | Ying Jiang Yong Wang Yu Yang Zhang Zhengfei Zhang Wentao Yuan Chenghua Sun Xiao Wei Casey N. Brodsky Chia-Kuang Tsung Jixue Li Xiaofeng Zhang Scott X. Mao Shengbai Zhang Ze Zhang | 2014 | Nano Research2014,7,3: | 4 |
| 6 | Schistosoma japonicum egg antigens stimulate CD4(+) CD25(+) T cells and modulate airway inflammation in a murine model of asthma显示文摘 | Yang, J. H. Zhao, J. Q. Yang, Y. F. Zhang, L. Yang, X. Zhu, X. Ji, M. J. Sun, N. X. Su, C. | 2007 | 南京医科大学学报(自然科学版)2007,27,5: | 4 |
| 7 | Wide Absorption Spectrum Measuring Methods by DFB-LDs in Water Vapor Detection System显示文摘由分布式的反馈激光二极管(DFB-LDs ) 的宽吸收光谱的二测量方法在检测水蒸汽吸收线被介绍。一个人是扫描方法的分部,并且由当前的调整由温度调整和快光谱调节速度调节范围利用宽光谱。明确地,这个方法被划分一个目标认识到光谱区域进对应于 DFB-LD 的特定的温度的几节,为百由当前的调整扫描每节预定,并且平均数据提起信号到噪音比率( SNR ),然后联合所有节得到整个系列。10 ppmv 的精确性被这个方法与 10 厘米的路径长度在水蒸汽的测量获得了。另外一个是适合方法的数据,基于吸收线形状功能;吸收线能被与部分测量数据适合描述。恰当的吸收线与测量数据被适合很好,并且关联系数(R 平方) 的平方是不亚于 0.99。 | Y. N. LIU J. CHANG J. LIAN Q. WANG G. P. LV W. J. WANG Z. LIU X. Z. LIU S. S. ZHANG Z. L. WANG S. JIANG C. G. ZHU W. WEI B.N. SUN | 2014 | Photonic Sensors2014,4,3: | 2 |
| 8 | Comparison of the genetic diversity of common wild rice (Oryza rufipogon Griff.) and cultivated rice (O. sativa L.) using RFLP markers显示文摘 | C. Q. Sun X. K. Wang Z. C. Li A. Yoshimura N. Iwata | 2001 | TAG Theoretical and Applied Genetics2001,,1: | 1 |
| 9 | 1-D Modeling of Hydrate Depressurization in Porous Media显示文摘 | X. Sun N. Nanchary K. K. Mohanty | 2005 | Transport in Porous Media2005,,3: | 1 |
| 10 | The efficacy and safety of leflunomide therapy in lupus nephritis by repeat kidney biopsy显示文摘 | F. S. Zhang Y. K. Nie X. M. Jin H. M. Yu Y. N. Li Y. Sun | 2009 | Rheumatology International2009,,11: | 1 |
| 11 | Comparison of the genetic diversity of common wild rice (Oryza rufipogon Griff.) and cultivated rice (O. sativa L.) using RFLP markers显示文摘 | C. Q. Sun X. K. Wang Z. C. Li A. Yoshimura N. Iwata | 2001 | TAG Theoretical and Applied Genetics2001,,1: | 1 |
| 12 | Wide Gap TLP Bonding a Single-Crystal Superalloy: Evolution of the L/S Interface Morphology and Formation of the Isolated Grain Boundaries显示文摘 | N. C. Sheng J. D. Liu T. Jin X. F. Sun Z. Q. Hu | 2013 | Metallurgical and Materials Transactions A2013,,4: | 1 |
| 13 | Recovery from Mercury Contamination in the Second Songhua River, China显示文摘 | Z. S. Zhang X. J. Sun Q. C. Wang D. M. Zheng N. Zheng X. G. Lv | 2010 | Water Air & Soil Pollution (-)2010,,1: | 1 |
| 14 | Hydrodynamics behaviour of oil field wastewater advanced treatment by ultrafiltration process显示文摘 | X.S. Yi S.L. Yu W.X. Shi S. Wang N. Sun L.M. Jin X. Wang L.P. Sun | 2012 | Desalination2012,,: | 1 |
| 15 | Oxidation Behavior and Breakdown of an Aluminide Coating on DZ40M Alloy at High Temperatures显示文摘 | P.S. Liu K. M. Liang H. Y. Zhou H. R. Guan X. F. Sun T. Jin K. N. Yang | 2001 | Oxidation of Metals (-)2001,,5: | 1 |
| 16 | Expression of the cyclin-dependent kinase inhibitor p27 and its deregulation in mouse B cell lymphomas显示文摘 | Chen-Feng Qi Shao Xiang Min Sun Shin Xingpei Hao Chang Hoon Lee Jeff X. Zhou Ted A. Torrey Janet W. Hartley Torgny N. Fredrickson Herbert C. Morse | 2005 | Leukemia Research2005,,2: | 1 |
| 17 | Localized amorphism after high-strain-rate deformation in TWIP steel显示文摘 | N. Li Y.D. Wang R. Lin Peng X. Sun P.K. Liaw G.L. Wu L. Wang H.N. Cai | 2011 | Acta Materialia2011,,16: | 1 |
| 18 | Comparison of the genetic diversity of common wild rice (Oryza rufipogon Griff.) and cultivated rice (O. sativa L.) using RFLP markers显示文摘 | C. Q. Sun X. K. Wang Z. C. Li A. Yoshimura N. Iwata | 2001 | TAG Theoretical and Applied Genetics2001,,1: | 1 |
| 19 | The efficacy and safety of leflunomide therapy in lupus nephritis by repeat kidney biopsy显示文摘 | F. S. Zhang Y. K. Nie X. M. Jin H. M. Yu Y. N. Li Y. Sun | 2009 | Rheumatology International2009,,11: | 1 |
| 20 | Comparison of the genetic diversity of common wild rice (Oryza rufipogon Griff.) and cultivated rice (O. sativa L.) using RFLP markers显示文摘 | C. Q. Sun X. K. Wang Z. C. Li A. Yoshimura N. Iwata | 2001 | TAG Theoretical and Applied Genetics2001,,1: | 1 |