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363篇 您的检索式：作者名="Suarez M J"

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	题名	作者	年代	出处	被引量
1	Conversion from calcineurin inhibitors to mTOR inhibitors stabilizes diabetic and hypertensive nephropathy after liver transplant显示文摘AIM: To investigate if conversion to the mammalian target of rapamycin inhibitors(mTORi) improves renal function in diabetic and/or hypertensive liver transplant patients immunosuppressed with tacrolimus or cyclosporine.METHODS: The study included 86 liver graft recipients immunosuppressed with mTORi treatment after orthotopic liver transplantation(OLT), including all liver recipients with worsening renal function before conversion to mTORi(n = 55 patients) and recipients with normal renal function who converted to m TORi for other reasons(n = 31 patients). We identified patients with diabetes mellitus(n = 28), arterial hypertension(n = 27), proteinuria(n = 27) and all three factors(n = 8)(some patients have hypertension and diabetes and no proteinuria). The primary endpoint was evolution in renal function defined as the development in plasma creatinine as a function of diabetes mellitus(DM), hypertension(HT) or proteinuria. We required elevated serum creatinine for at least two weeks to define renal dysfunction.RESULTS: Only patients that converted because of renal failure with plasma creatinine levels > 1.5 mg/dL showed an improvement of renal function(2.14 to 1.77 mg/dL)(P = 0.02). Patients with DM showed no improvement of serum creatinine levels(1.31 mg/dL to 1.37 mg/dL) compared with non DM patients(1.31 mg/dL to 1.15 mg/dL)(P = 0.01), HT patients(1.48 mg/dL to 1.5 mg/dL) with non HT patients(1.21mg/d L to 1.08 mg/dL) and patients with proteinuria(1.44 mg/dL to 1.41 mg/dL) and no proteinuria(1.31 mg/dL to 1.11 mg/dL). CONCLUSION: In OLT recipients with diabetes or hypertensive nephropathy, conversion to m TORi does not improve renal function but stabilizes plasma levels of creatinine. Proteinuria is not a contraindication to conversion to m TORi; it also stabilizes renal function. Conversion to m TORi should only be avoided in patients with diabetes, hypertension and proteinuria.	José M álamo Claudia Olivares Lydia Barrera Luis M Marín Gonzalo Suarez Carmen Bernal Juan Serrano Jordi Muntané Francisco J Padillo Miguel A Gómez	2015	World Journal of Transplantation2015，5，1：	6
2	Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis显示文摘	Rayner Katey J Sheedy Frederick J Esau Christine C Hussain Farah N Temel Ryan E Parathath Saj van Gils Janine M Rayner Alistair J Chang Aaron N Suarez Yajaira Fernandez-Hernando Carlos Fisher Edward A Moore Kathryn J	2011	Journal of Clinical Investigation2011，，7：	2
3	Ni- tric oxide synthase inhibition and food intake effects on motivation to eat and in female mice 显示文摘	MORLEY J E FARR S A SUAREZ M D	1995	Pharma- cology Biochemistry and Behavior1995，50，3：	1
4	Effect of age of feed restriction and microelement supplementa- tion to control ascites on production and carcass charac- teristics of broilers 显示文摘	Camacho M A Suarez M E Herrera J G	2004	Poultry Science2004，，83：	1
5	A simple framework for examing the interannual variability of land surface moisture flux-es显示文摘	Koster R D Suarez M J		0，，12：	1
6	Design and Performance Analysis of a Massively Parallel Atmospheric General Circulation Model显示文摘	Schaffer D S Suarez M J	2000	Scientific Programming2000，8，1：	1
7	Value of the ankle-brachial index in cardiovascular risk stratification of patients without known atherotrom-hotic disease显示文摘	MANZANO L MOSTAZA J M SUAREZ C	2007	Med Clin (Barc)2007，128，：	1
8	An effcient thermal infrared radiation parameterization for use in general circulation models 显示文摘	Chou M D Suarez M J	1994	NASA Tech Memo 1046061994，3，：	1
9	Immediate andfollow-up findings after stentt treatment for severe eoareta- tion of aorta显示文摘	Suarez de Lezo J Pan M Romero M	1999	Am J Cardiol1999，83，：	1
10	Balloon-expandable stent repair of severe coarctation of aorta显示文摘	Suarez de Lezo J Pan M Romero M	1995	Am Heart J1995，129，：	1
11	Dominant designs and the survival of firms显示文摘	SUAREZ F F UTTERBACK J M	1995	Strategic Management Journal1995，16，6：	1
12	Absorption kinetics of sulfur dioxide in flint corn during steeping 显示文摘	HAROS C M AGUERRE R J SUAREZ C	2001	LWT-Food Science and Technology2001，34，5：	1
13	Modeling sulfur dioxide uptake in dent corn during steeping显示文摘	HAROS C M AGUERRE R J SUAREZ C	2005	LWT-Food Science and Technology2005，38，4：	1
14	A delayed action oscillator for EN SO显示文摘	SUAREZ M J SCHOPF P S	1988	Journal of the atmospheric sciences1988，45，：	1
15	Effect of high pressure processing (HPP) on shelf life of albacore tuna (Thunnus alal unga) minced muscle显示文摘	Ramirez Suarez J C Morrissey M T	2006	Innovative Food Science - Emerging Technologies2006，7，1：	1
16	Gas chromatographic-mass spectrometric method for the determination of bisphenol A and its chlorinated derivatives in urban wastewater 显示文摘	Zafra A del Olmo M Suarez B Hontoria E Navalon A O Vilchez J L	2003	Water Research2003，37，：	1
17	Further evidence of the role of frizzled - related protein gene polymorphisms in osteoarthritis显示文摘	Rodriguez - Lopez J Pombo - Suarez M Liz M	2007	Ann Rheum Dis2007，8，：	1
18	Selective lin- ear dimerization of 1,3-butadiene by palladium compounds immobilized into 1-n-butyl-3-methyl imidazoli- urn ionic liquids 显示文摘	Silva S M Suarez P A Z Dupont J	1998	Polymer Bulletin1998，40，45：	1
19	Identifying gp85-regions involved in Epstein-Barr virus binding to B Lymphocytes显示文摘	Urquiza M Suarez J Lopez R	2004	Biochem Biophy Res Commun2004，319，1：	1
20	Generation of foodgrade recombinant lactic acid bacterium strains by site-specific recombination显示文摘	MARTIN M C ALONSO J C SUAREZ J E	2000	Appl Environ Microbiol2000，66，：	1

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