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| 1 | Does low volume high-intensity interval training elicit superior benefits to continuous low to moderate-intensity training in cancer survivors?显示文摘AIM To determine the impact ofm low volume high-intensity interval training(LVHIIT) and continuous low to moderate-intensity exercise training(CLMIT) on cardiovascular disease(CVD) risk and health outcomes in cancer survivors.METHODS Sedentary cancer survivors(n=75,aged 51±12year)within 24 months of diagnosis,were randomised into three groups for 12 wk of LVHIIT(n=25),CLMIT(n=25)or control group(n=25).The exercise intervention involved 36 sessions(three sessions per week).The LVHIIT group performed 7 x 30 s intervals(≥85%predicted maximal heart rate)with a 60 s rest between intervals,and the CLMIT group performed continuous aerobic training for 20 min(≤55%predicted maximal heart rate)on a stationary bike.Outcome variables were measured at baseline and at12 weeks and analysed using a 3 x 2(group x time)repeated measures ANCOVA to evaluate main and interaction effects.RESULTS Significant improvements(time)were observed for seven of the 22 variables(ES 0.35-0.97,P≤0.05).There was an interaction effect(P<0.01)after 12 in the LVHIIT group for six-minute walk test(P<0.01;d=0.97;95%CI:0.36,1.56;large),sit to stand test(P<0.01;d=-0.83;95%CI:-1.40,-0.22;large)and waist circumference reduction(P=0.01;d=-0.48;95%CI:-1.10,0.10;medium).An interaction effect(P<0.01)was also observed for quality of life in both the LVHIIT(d=1.11;95CI:0.50,1.72;large)and CLMIT(d=0.57;95%CI:-0.00,1.20;moderate)compared with the control group(d=-0.15;95%CI:-0.95,0.65;trivial).CONCLUSION Low-volume high-intensity training shows promise as an effective exercise prescription within the cancer population,showing greater improvements in cardiorespiratory fitness,lower body strength and waist circumference compared with traditional CLMIT and control groups.Both LVHIIT and CLMIT improved quality of life.A proposed benefit of LVHIIT is the short duration(3 min)of exercise required,which may entice more cancer survivors to participate in exercise,improving health outcomes and lowing the risk of CVD. | Kellie Toohey Kate Pumpa Andrew McKune Julie Cooke Katrina D DuBose Desmond Yip Paul Craft Stuart Semple | 2018 | World Journal of Clinical Oncology2018，9，1： | 3 |
| 2 | Regulation of Bcl-2 Family Proteins During Development and in Response to Oxidative Stress in Cardiac Myocytes: Association With Changes in Mitochondrial Membrane Potential显示文摘 | Stuart A. Cook Peter H. Sugden Angela Clerk | 1999 | Circulation Research: Journal of the American Heart Association1999，，10： | 2 |
| 3 | Transcriptional effects of chronic Akt activation in the heart 显示文摘 | STUART A COOK TAKASHI MATSUI LING L I | 2002 | J Biological Chemistry2002，277，22： | 1 |
| 4 | A Place- bo-Controlled Trial of Oral Cladribine for Relapsing Multiple Scle- rosis显示文摘 | Gavin Giovannoni Giancarlo Comi Stuart Cook | 2010 | The New England Journal of Medicine2010，362，： | 1 |
| 5 | Optimization of direct conversion of wet algae to biodiesel under supercritical methanol conditions显示文摘 | Prafulla D. Patil Veera Gnaneswar Gude Aravind Mannarswamy Shuguang Deng Peter Cooke Stuart Munson-McGee Isaac Rhodes Pete Lammers Nagamany Nirmalakhandan | 2010 | Bioresource Technology2010，，1： | 1 |
| 6 | Cigarette smoke extract induced cytokine and chemokine gene expression changes in COPD macrophages显示文摘 | Lauren Kent Lucy Smyth Chris Clayton Laurie Scott Ted Cook Richard Stephens Steve Fox Peter Hext Stuart Farrow Dave Singh | 2008 | Cytokine2008，，2： | 1 |
| 7 | A Place- bo-Controlled Trial of Oral Cladribine for Relapsing Multiple Scle- rosis显示文摘 | Gavin Giovannoni Giancarlo Comi Stuart Cook | 2010 | The New England Journal of Medicine2010，362，： | 1 |
| 8 | Midwall Fibrosis Is an Independent Predictor of Mortality in Patients With Aortic Stenosis显示文摘 | Marc R. Dweck Sanjiv Joshi Timothy Murigu Francisco Alpendurada Andrew Jabbour Giovanni Melina Winston Banya Ankur Gulati Isabelle Roussin Sadaf Raza Nishant A. Prasad Rick Wage Cesare Quarto Emiliano Angeloni Simone Refice Mary Sheppard Stuart A. Cook Ph | 2011 | Journal of the American College of Cardiology2011，，12： | 1 |
| 9 | Changing tyres: Why natural rubber can meet demands of the modern type 显示文摘 | Dr Stuart cook | 2009 | Materials World2009，17，10： | 1 |
| 10 | Midwall Fibrosis Is an Independent Predictor of Mortality in Patients With Aortic Stenosis显示文摘 | Marc R. Dweck Sanjiv Joshi Timothy Murigu Francisco Alpendurada Andrew Jabbour Giovanni Melina Winston Banya Ankur Gulati Isabelle Roussin Sadaf Raza Nishant A. Prasad Rick Wage Cesare Quarto Emiliano Angeloni Simone Refice Mary Sheppard Stuart A. Cook Ph | 2011 | Journal of the American College of Cardiology2011，，： | 1 |
| 11 | CeO 2 nano-precipitation in borosilicate glasses: A redox study using EELS显示文摘 | Guang Yang Stuart Cook Russell J. Hand Günter M?bus | 2009 | Journal of the European Ceramic Society2009，，4： | 1 |
| 12 | Kidney Transplantation With Sirolimus and Mycophenolate Mofetil–Based Immunosuppression: 5-Year Results of a Randomized Prospective Trial Compared to Calcineurin Inhibitor Drugs显示文摘 | Stuart M. Flechner David Goldfarb Kim Solez Charles S. Modlin Barbara Mastroianni Kathy Savas Denise Babineau Sunil Kurian Daniel Salomon Andrew C. Novick Daniel J. Cook | 2007 | Transplantation2007，，7： | 1 |
| 13 | STAT3 is a central regulator of lymphocyte differentiation and function显示文摘 | Alisa Kane Elissa K. Deenick Cindy S. Ma Matthew C. Cook Gulbu Uzel Stuart G. Tangye | 2014 | Current Opinion in Immunology2014，，： | 1 |
| 14 | Detection of a possible superluminous supernova in the Epoch of Reionization显示文摘The Epoch of Reionization(EoR)poses a number of puzzles,including the sufficiency of ionizing radiation,the rapid production of supermassive black holes and the early appearance of abundant metals in larger galaxies.For the first of these,solutions focus on the main sequence evolution of massive stars,but the second and third puzzles involve the terminal phase of stellar evolution, | Jeremy Mould Tim Abbott Jeff Cooke Chris Curtin Antonios Katsianis Anton Koekemoer Edoardo Tescari Syed Uddin Lifan Wang Stuart Wyithe | 2017 | Science Bulletin2017，62，10： | 0 |
| 15 | 乳縻性心包积液显示文摘2008年2月,一27岁的男子参加了一个军事训练班。在热身慢跑时患者出现虚脱表现。目击者未观察到其有典型癫痫样运动。患者在2min内恢复正常,并步行至本急诊科。常规检查未发现异常。心电图示侧壁导联T波倒置,但无其他异常。血液学检查(包括12h肌钙蛋门检测)结果均正常。 | Andrew Potter Kevin Fox Stuart Cook Prakash Punjabi Susan Connolly 徐绍鹏(译) | 2009 | 世界临床医学2009，，11： | 0 |
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