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| 1 | Long-term Benefit of Sustained-Delivery Fluocinolone Acetonide Vitreous Inserts for Diabetic Macular Edema显示文摘 | Peter A. Campochiaro David M. Brown Andrew Pearson Thomas Ciulla David Boyer Frank G. Holz Michael Tolentino Amod Gupta Lilianne Duarte Steven Madreperla John Gonder Barry Kapik Kathleen Billman Frances E. Kane | 2011 | Ophthalmology2011，，4： | 2 |
| 2 | Patient and surgeon ranking of the severity of symptoms associated with fecal incontinence显示文摘 | Todd H. Rockwood James M. Church James W. Fleshman Robert L. Kane Constantinos Mavrantonis Alan G. Thorson Steven D. Wexner Donna Bliss R.N. Ann C. Lowry | 1999 | Diseases of the Colon & Rectum1999，，12： | 2 |
| 3 | The Planktonic Index of Biotic Integrity (P-IBI): An approach for assessing lake ecosystem health显示文摘 | Douglas D. Kane Steven I. Gordon Mohiuddin Munawar Murray N. Charlton David A. Culver | 2009 | Ecological Indicators2009，，6： | 2 |
| 4 | A COMPARISON OF CYTOLOGY AND FLUORESCENCE IN SITU HYBRIDIZATION FOR THE DETECTION OF UROTHELIAL CARCINOMA显示文摘 | KEVIN C. HALLING WALTER KING IRINA A. SOKOLOVA REID G. MEYER HALEH M. BURKHARDT AMY C. HALLING JOHN C. CHEVILLE THOMAS J. SEBO SANJAY RAMAKUMAR CHRISTOPHER S. STEWART SHANE PANKRATZ DENNIS J. O’KANE STEVEN A. SEELIG MICHAEL M. LIEBER ROBERT B. JENKINS | 2000 | The Journal of Urology2000，，5： | 1 |
| 5 | In vivo deforma-tion,surface damage,and biostability of retrieved Dynesys systems显示文摘 | Ianuzzi AlIyson Kurtz Steven Kane William | 2010 | Eur Spine J2010，35，： | 1 |
| 6 | Visual performance with night vision goggles after photorefractive keratectomy for myopia显示文摘 | Subramanian PS O' Kane B Stefanik R Stevens J Rabin J Bauer RM | 2003 | Ophthalmology2003，110，： | 1 |
| 7 | The International Suicide Prevention Trial (InterSePT): Rationale and Design of a Trial Comparing the Relative Ability of Clozapine and Olanzapine To Reduce Suicidal Behavior in Schizophrenia and Schizoaffective Patients显示文摘 | Larry Alphs Ravi Anand M. Zahur Islam Herbert Y. Meltzer John M. Kane Ranga Krishnan Alan I. Green Steven Potkin Guy Chouinard Jean-Pierre Lindenmayer Rob Kerwin | 2004 | Schizophrenia Bulletin2004，，： | 1 |
| 8 | A COMPARISON OF CYTOLOGY AND FLUORESCENCE IN SITU HYBRIDIZATION FOR THE DETECTION OF UROTHELIAL CARCINOMA显示文摘 | KEVIN C. HALLING WALTER KING IRINA A. SOKOLOVA REID G. MEYER HALEH M. BURKHARDT AMY C. HALLING JOHN C. CHEVILLE THOMAS J. SEBO SANJAY RAMAKUMAR CHRISTOPHER S. STEWART SHANE PANKRATZ DENNIS J. O’KANE STEVEN A. SEELIG MICHAEL M. LIEBER ROBERT B. JENKINS | 2000 | The Journal of Urology2000，，5： | 1 |
| 9 | Fecal incontinence quality of life scale显示文摘 | Todd H. Rockwood James M. Church James W. Fleshman Robert L. Kane Constantinos Mavrantonis Alan G. Thorson Steven D. Wexner Donna Bliss Ann C. Lowry | 2000 | Diseases of the Colon & Rectum2000，，1： | 1 |
| 10 | Altered perception of floaters in dementia causing selfinflicted injuries显示文摘Dear Editor,A 74 years old male patient with history of Parkinson disease and vascular dementia presented to the eye clinic with his wife,who is his primary caregiver.The patient reported a multiple year history of complaining of'flies'around his head,which were a source of considerable agitation.He was so bothered by constantly seeing these flies that he carried a custom flyswatter with him(Figure 1)at all times. | Will Griffeth Steven Kane Syed Khurshid Gibran | 2017 | International Journal of Ophthalmology(English edition)2017，10，7： | 1 |
| 11 | Differential Regulation of the Cynomolgus, Human, and Rat Aeyl-CoA Oxidase Promoters by PPARalpha显示文摘 | Kane C D Franeone O L Stevens K A | 2006 | Gene2006，380，2： | 1 |
| 12 | Patient and surgeon ranking of the severity of symptoms associated with fecal incontinence显示文摘 | Todd H. Rockwood Ph.D. James M. Church M.D. James W. Fleshman M.D. Robert L. Kane M.D. Constantinos Mavrantonis M.D. Alan G. Thorson M.D. Steven D. Wexner M.D. Donna Bliss R.N. Ph.D. Ann C. Lowry M.D | 1999 | Diseases of the Colon & Rectum1999，，12： | 1 |
| 13 | Sustained Ocular Delivery of Fluocinolone Acetonide by an Intravitreal Insert显示文摘 | Peter A. Campochiaro Gulnar Hafiz Syed Mahmood Shah Steven Bloom David M. Brown Miguel Busquets Thomas Ciulla Leonard Feiner Nelson Sabates Kathleen Billman Barry Kapik Ken Green Frances Kane | 2010 | Ophthalmology2010，，7： | 1 |
| 14 | Germline BRCA2 variants in advanced pancreatic acinar cell carcinoma:A case report and review of literature显示文摘BACKGROUND Pancreatic acinar cell carcinoma(PACC)is a rare tumor.Up to 45%of PACCs have alterations in the DNA damage repair pathway and 23%harbor rearrangements in the BRAF or RAF1 genes.We present a PACC case with a germline BRCA2 likely pathogenic variant(LPV)to highlight the impact of genomic testing on treatment decisions and patient outcomes.In our larger case series,we provide clinic-based information on additional 10 PACC patients treated in our center.CASE SUMMARY A 70-year-old male was diagnosed with advanced PACC.At presentation,he was cachectic with severe arthralgia despite prednisolone and a skin rash that was later confirmed to be panniculitis.He was treated with modified FOLFIRINOX(mFFX)with the knowledge of the germline BRCA2 LPV.Following 11 cycles of mFFX,a computed tomography(CT)scan demonstrated significant tumor response in the pancreatic primary and hepatic metastases,totaling 70%from baseline as per Response Evaluation Criteria in Solid Tumors.Resolution of the skin panniculitis was also noted.We identified two additional PACCs with druggable targets in our case series.Our data contribute to practical evidence for the value of germline and somatic profiling in the management of rare diseases like PACC.CONCLUSION This patient and others in our larger case series highlight the importance of genomic testing in PACC with potential utility in personalized treatment. | Cha Len Lee Spring Holter Ayelet Borgida Anna Dodd Stephanie Ramotar Robert Grant Kristy Wasson Elena Elimova Raymond W Jang Malcolm Moore Tae Kyoung Kim Korosh Khalili Carol-Anne Moulton Steven Gallinger Grainne M O’Kane Jennifer J Knox | 2022 | World Journal of Gastroenterology2022，28，45： | 0 |
| 15 | Rapid retinal functional testing显示文摘The most prominent causes of loss of vision in individuals over 50 years include age-related macular degeneration(AMD),glaucoma,and diabetic retinopathy(DR).While it is important to screen for these diseases effectively,current eye care is not properly doing so for much of the population,resulting in unfortunate visual disability and high costs for patients.Innovative functional testing can be unified with other screening methods for a more robust and safer screening and prediction of disease.The goal in the creation of functional testing modalities is to develop highly sensitive screening tests that are easy to use,accessible to all users,and inexpensive.The tests herein are deployed on an iPad with easily understood and intuitive instructions for rapid,streamlined,and automatic administration.These testing modalities could become highly sensitive screenings for early detection of potentially blinding diseases.The applications from our collaborators at AMA Optics include a cone photostress recovery test for detection of AMD and diabetic macular edema(DME),brightness balance perception for optic nerve dysfunction and especially glaucoma,color vision testing which is a broad screening tool,and visual acuity test.Machine learning with the combined structural and functional data will optimize identification of disease and prediction of outcomes.Here,we review and assess various tests of visual function that are easily administered on a tablet for screening in primary care.These user-friendly and simple screening tests allow patients to be identified in the early stages of disease for referral to specialists,proper assessment and treatment. | Sarah A.Weitzman Vivienne Greenstein Alauddin Bhuiyan Albert Hofeldt Steven Kane | 2021 | Annals of Eye Science2021，，3： | 0 |
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