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31篇 您的检索式:作者名="Stec E"
    题名 作者 年代 出处 被引量
1Lean heart: Role of leptin in cardiac hypertrophy and metabolism显示文摘Leptin is an adipokine that has been linked with the cardiovascular complications resulting from obesity such as hypertension and heart disease. Obese patients have high levels of circulating leptin due to increased fat mass. Clinical and population studies have correlated high levels of circulating leptin with the development of cardiac hypertrophy in obesity. Leptin has also been demonstrated to increase the growth of cultured cardiomyocytes. However, several animal studies of obese leptin deficient mice have not supported a role for leptin in promoting cardiac hypertrophy so the role of leptin in this pathological process remains unclear. Leptin is also an important hormone in the regulation of cardiac metabolism where it supports oxidation of glucose and fatty acids. In addition, leptin plays a critical role in protecting the heart from excess lipid accumulation and the formation of toxic lipids in obesity a condition known as cardiac lipotoxicity. This paper focuses on the data supporting and refuting leptin's role in promoting cardiac hypertrophy as well as its important role in the regulation of cardiac metabolism and protection against cardiac lipotoxicity.Michael E Hall Romain Harmancey David E Stec 2015World Journal of Cardiology2015,7,9:7
2Moderate hyperbilirubinemiaimproves renal hemodynamics in ANGⅡ-dependenthypertension显示文摘VERA T STEC D E 2010Am J Physiol Regul Integr CompPhysiol2010,299,:1
3A cell-based beta-lactamase reporter gene assay for the identification of inhibitors of hepatitis C virus replication显示文摘Zuck P Murray EM Stec E 2004Anal Biochem2004,334,2:1
4Expression of heme oxygen- ase-1 in thick ascending loop of henle attenuates angiotensin Ⅱ- dependent hypertension显示文摘Stec DE Drummond HA Gousette MU Storm MV Abraham NG Csongradi E 2012J Am Soc Nephrol2012,23,5:1
5Induction of heine oxygenase 1 attenu- ates placental ischemia-induced hypertension 显示文摘George EM Cockrell K Aranay M Csongradi E Stec DE Granger JP 2011Hyperten- sion2011,57,5:1
6Inner-orbital binding-energy shifts of antimony and bismuth compounds显示文摘Morgan W E Stec W J Wazer J R 1973Inorg Chem1973,12,4:1
7Inhibition of bilirubin metabolism induces moderate hyperbilirub in emia and attenuates ANGII -dependent hypertension in mice显示文摘VERA T GRANGER J P STEC D E 2009Am J Physiol Regul Integr Comp Physiol2009,297,3:1
8Interaction of COP1 and UVR8 regulates UV-B-induced photomorphogenesis and stress acclimation in Arabidopsis显示文摘Favory J Stec A Gruber H Rizzini L Oravecz A Funk M Albert A Cloix C Jenkins G I Oakeley E J Seidlitz H K Nagy F Ulm R 0,,:1
9AdEasy system made easier by selecting the viral backbone plasmid pre- ceding homologous recombination 显示文摘Stec D E Morimoto S Sigmund C D 2001Biotechniques2001,31,2:1
10A complete set of maize individual chromosome addition to the oat genome显示文摘Kynast R G Riera-Lizarazu O Isabel Vales M Okagaki R J Maquieira S B Chen G Ananiev E V Odland W E Russell C D Stec A O Livingston S M Zaia H A Rines H W Phillips R L 2001Plant Physiol2001,125,:1
11Laser Doppler measurements of the vocal fold blood micro-circulation 显示文摘Stec I Hertegard S Juto J E 2007Journal of Voice2007,21,3:1
12Common variants of cytochrome P450 4F2 exhibit altered vitamin E-co-hydroxylase specific activity 显示文摘BARDOWELL S A STEC D E PARKER R S 2010J Nutr2010,140,:1
13A revised mechanism for the alkaline phosphatase reaction involving three metal ions 显示文摘Stec B Holtz K M Kantrowitz E R 2000J Mol Biol2000,299,5:1
14A cell-based beta-lactamase reporter gene assay for the identification of inhibitors of hepatitis C virus replication显示文摘Zuck P Murray EM Stec E 2004Anal Biochem2004,334,2:1
15A revised mechanism for the alkaline phosphatase reaction involving three metal ions显示文摘Stec B Holtz K M Kantrowitz E R 2000J Mol Biol2000,299,5:1
16Inhibition of bilirubin metabolism induces moderate hyperbilirubinemia and attenuates ANG II-dependent hypertension in mice显示文摘VERA T GRANGER J P STEC D E 2009Am J Physiol Regul Integr Comp Physiol2009,297,3:1
17Renal inhibitionof heme-oxygenase- 1 increases blood pressure in angiotensin I-I-dependent hypertension显示文摘CSONGRADI E STORM MV STEC DE 2012Int J Hypertens2012,2012,49:1
18A revised mechanism for the alkaline phosphatase reaction involving three metal ions显示文摘STEC B HOLTZ K M KANTROWITZ E R 2000J Mol Biol2000,299,5:1
19Distribution of cytochrome P-450 4A and 4F isoforms along the nephron in mice显示文摘Stec D E Flasch A Romen R J White J A 2003Am J Physiol Renal Physiol2003,284,:1
20Inhibition of bilirubin metabolism induces moderate hyperbilirubinemia and attenuates ANG II -dependent hypertension in mice显示文摘VERA T GRANGER JP STEC D E 2009Am J Physion Reg- ul Integr Comp Physion2009,297,3:1
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