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1利用组织工程的方法预制含双面表皮的游离皮瓣显示文摘目的 探讨利用组织扩张器和培养的角质上皮细胞预制含双面表皮的游离皮瓣的可行性。 方法 在 10只大鼠的右下腹腹壁下动静脉皮瓣下各埋置一 10 ml容积的扩张器 ,7天后将体外培养的 10× 10 6同系鼠角质上皮细胞用 1ml纤维蛋白胶 ( fibrin glue)制成悬液后接种到扩张器与包囊之间的间隙 ,大体及组织学观察移植的角质上皮细胞是否能将扩张器外纤维包囊上皮化以形成一含双面表皮的皮瓣。皮瓣预制成功后 ,以腹壁下动静脉连同一段股动静脉为蒂行游离移植覆盖颊部洞穿性缺损。 结果 大体观察及组织学证明培养的角质上皮细胞纤维蛋白胶悬液移植后可以将扩张器的纤维包囊上皮化。 结论 利用组织工程的方法可以预制含双面表皮的皮瓣。焦向阳 邢新 郭恩覃 Tanczos E Stark GB 1999中华显微外科杂志1999,22,4:3
2卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景 缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 2017国际脑血管病杂志2017,25,5:2
3Changes in efficiency and resource utilization after increasing experience with double balloon enteroscopy显示文摘AIM:To investigate changes in efficiency and resource utilization as a single endoscopist's experience increased with each subsequent 100 double balloon enteroscopy(DBE) procedures.METHODS:We reviewed consecutive DBE procedures performed by a single endoscopist at our center over 4 years.DBE was employed when the clinician deemed the procedure was needed for disease management.The approach(oral,anal or both) was chosen based on suspected location of the target lesion.All DBE was performed in a standard endoscopy room with a portable fluoroscopy unit.Fluoroscopy was used to aid in shortening the small intestine and reducing bowel loops.For oral DBE,measurements were taken from the incisors.For anal DBE,measurements were taken from the anal verge.Enteroscopy continued until the target lesion was reached,until the entire small intestine was examined,or until no further progress was deemed possible.The length of small intestine examined(cm),procedure duration(min),and fluoroscopy time(s) were analyzed for sequential groups of 100 DBE.Sub-groups of diagnostic and therapeutic procedures were analyzed using multivariable linear regression.RESULTS:802 consecutive DBE procedures were analyzed.For oral DBE,median [interquartile range(IQR)] length of small bowel examined was 230.8 cm(range:210-248 cm) and for anal DBE was 143.5 cm(range:100-180 cm).No significant increase in length examined was noted for either the oral or anal approach with advancing position in series.In terms of duration of procedure,the median(IQR) for oral DBE was 86 min(range:71-105 min) and for anal DBE was 81.3 min(range:67-105 min).When comparing by the position in series,there was a significant(P value < 0.001) decrease in procedure duration for both upper and lower procedures with increasing experience.Median(IQR) time of exposure to fluoroscopy for oral DBE was 190 s(114-275) compared to anal DBE which was 196.4 s(312-128).This represented a significant(P value < 0.001) decrease in the amount of fluoroscopy used with increasing position in series.For both oral and anal DBE,fluoroscopy time was reduced by greater than 50% over the course of 802 total procedures performed.Sub-group analysis was conducted on therapeutic and diagnostic groups.Out of 802 procedures,a total of 434 were considered therapeutic.Argon plasma coagulation was by far the most common therapeutic intervention performed.There was no evidence of a difference in length examined or fluoroscopy exposure among oral DBE for diagnostic and therapeutic procedures,P = 0.91 and P = 0.32 respectively.The median(IQR) for length was 235 cm(range:178-280 cm) for diagnostic vs 230 cm(range:180-275 cm) for therapeutic procedures;additionally,fluoroscopy time median(IQR) was 180 s(range:110-295 s) and 162 s(range:102-263 s) for no intervention and intervention.However,there was a significant difference in procedure duration among oral DBE(P < 0.001).The median(IQR) was 80 min(range:60-97 min) and 94 min(range:77-110 min) for diagnostic and therapeutic interventions respectively.CONCLUSION:For a single endoscopist,increased DBE experience with number of performed procedures is associated with increased efficiency and decreased resource utilization.Neal C Patel William C Palmer Kanwar R Gill David Cangemi Nancy Diehl Mark E Stark 2013World Journal of Gastrointestinal Endoscopy2013,5,3:2
4Fatigue crack growth rates for Al- Li -Cu -Mg alloys in vacuum显示文摘SLIVIK D C BLANKENSHIP C P STARKE JR E A 1993Metal Trans1993,22,3:2
5Particle-stimulated nucleation of recrystallization for grain-size control and superplasticity in an Al-Mg-Si-Cu alloy显示文摘TROEGER L P STARKE Jr E A 2000Materials Science and Engineering2000,293,:1
6Migration Incentives,Migration Types:The Role of Relative Deprlvation显示文摘Stark O Taylor J E 1991The Economic Journal1991,101,:1
7Insulator coated metal nanoparticles with a core/shell geometry exhibit a temperature sensitivity similar to advanced spinels 显示文摘Athanassiou E K Mensing C Stark W J 2007Advances in Physical2007,138,:1
8Effect of Copper Content and Heat Treatment on the Stress Corrosion Characteristics of Al-6Zn- 2Mg-XCu Alloys显示文摘Sarkar B Marek M Starke E A Jr 1981Metallurgical TransactionsA1981,12,11:1
9Particle-stimulated nucleation of recrystallization for grain-size control and superplasticity in an Al-Mg-Si-Cu alloy显示文摘Troeger L P Starke E A Jr 2000Mater Sci Eng A2000,293,:1
10Lymph edema: knowledge,treatment,and impact among breast cancer survivors 显示文摘PASKEU E D STARK N 2000Breast J2000,6,7:1
11Photo- graphic tone reproduction for digital images 显示文摘Reinhard E Stark M Shirley P 2002ACM Transactions on Graphics2002,21,3:1
12Managing irrigation and nitrogen fertility of hard spring wheats for optimum bread and noodle quality 显示文摘Guttieri M J McLean R Stark J C Souza E 2005Crop Science2005,45,:1
13Ribonuclease P: an enzyme with an essential RNA component 显示文摘STARK B C KOLE R BOWMAN E J 1978Proc Natl Acad Sci USA1978,75,8:1
14Application of modem aluminum al- loys to aircraft 显示文摘Starke E A Staley J T 1996Progress Aerospace Sci1996,32,23:1
15Effect of active immu- nization against GnRH on androstenone concentration, growth performance and carcass quality in intact male pig显示文摘Jaros P BUrgi E Stark K D C 2005Livestock Production Science2005,92,3:1
16Relative deprivation and international migration显示文摘Stark O Taylor J E 1989Demography1989,26,1:1
17Migrastatin and a new compound isoMigrastatin from Streptomyces platensis显示文摘Woo E J Starks Courtney M 2002J Antibiotics2002,55,2:1
18Performance of Ultra-Wideband Communications with Suboptimal Receivers in Multipath Channels显示文摘Choi O D Stark W E 2002IEEE Journal on Selected Areas in Communications2002,20,9:1
19Computer experi- ment on superposition of strengthening effects of dif- ferent particles显示文摘Zhu A W Csontos A Starke E A 1999Acta Materialia1999,47,6:1
20Chemotherapeutic drug in- duced ABCG2 promoter demethylatioo as a novel mechanism of ac- quired muhidrug resistance 显示文摘BRAM E E STARK M RAZ S 2009Neoplasia2009,11,12:1
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