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| 1 | 为争夺客户而战:传统银行如何应对互联网金融挑战显示文摘全球银行业新的局面正在形成,数字化技术正在侵蚀银行业务和市场份额,重构客户关系,重点是银行最注重的中间业务收入。随着数字化变革的提速,银行将被卷入一场客户争夺战。如何与互联网企业合作竞争,维护客户关系将成为银行业未来思考的重要主题。未来银行必须向金融科技和互联网巨头的核心竞争力发起挑战,以客户需求为核心提供便捷、贴心的客户体验,同时通过数字化改造逐步将自身转型成为行动敏捷的低成本竞争者,从根本上赢回客户。 | Miklos Dietz Philipp Harle Somesh Khanna 倪以理 曲向军 Christopher Mazingo 韩峰 马奔 | 2017 | 新金融2017，，1： | 3 |
| 2 | The MEKK1-MKK1/2-MPK4 cascade phosphorylates and stabilizes STOP1 to confer aluminum resistance in Arabidopsis显示文摘Aluminum(Al)toxicity can seriously restrict crop production on acidic soils,which comprise 40%of the world’s potentially arable land.The zinc finger transcription factor STOP1 has a conserved and essential function in mediating plant Al resistance.Al stress induces STOP1 accumulation via post-transcriptional regulatory mechanisms.However,the upstream signaling pathway involved in Al-triggered STOP1 accumulation remains unclear.Here,we report that the MEKK1-MKK1/2-MPK4 cascade positively regulates STOP1 phosphorylation and stability.Mutations of MEKK1,MKK1/2,or MPK4 lead to decreased STOP1 stability and Al resistance.Al stress induces the kinase activity of MPK4,which interacts with and phosphorylates STOP1.The phosphorylation of STOP1 reduces its interaction with the F-box protein RAE1 that mediates STOP1 degradation,thereby leading to enhanced STOP1 stability and Al resistance.Taken together,our results suggest that the MEKK1-MKK1/2-MPK4 cascade is important for Al signaling and confers Al resistance through phosphorylation-mediated enhancement of STOP1 accumulation in Arabidopsis. | Fanglin Zhou Somesh Singh Jie Zhang Qiu Fang Chongyang Li Jiawen Wang Chunzhao Zhao Pengcheng Wang Chao-Feng Huang | 2023 | Molecular Plant2023，16，2： | 1 |
| 3 | Head size and dislocation rate in primary total hip arthroplasty显示文摘 | Somesh Singh Haresh Bhalodiya | 2013 | Indian Journal of Orthopaedics2013，，5： | 1 |
| 4 | Genomie organization and ex- pression profile of the small GTPases of the RhoBTB family in human and mouse 显示文摘 | Ramos S Khademi F Somesh BP | 2002 | Gene2002，298，2： | 1 |
| 5 | Pattern recall anal- ysis of the Hopfield neural network with a genetic algo- rithm 显示文摘 | Somesh Kumar Manu Pratap Singh | 2010 | Computers & Mathematics with Applica- tions2010，60，4： | 1 |
| 6 | Design of self-compensated non contact capacitive sensors and proficient signal condition- ing circuit for mult threshold liquid level control - a no- vel approach显示文摘 | Babu C Somesh D H | 2006 | IEEE International Conference on Industrial Technology2006，，16： | 1 |
| 7 | Counterexample-guided abstraction refinement for symbolic model checking显示文摘 | Clarke E Grumberg O Somesh Jha | 2003 | Journal of the ACM2003，50，5： | 1 |
| 8 | Peroxisome proliferator-activated receptor-α selective ligand reduces adiposity, improves insulin sensitivity and inhibits atherosclerosis in LDL receptor-deficient mice显示文摘 | Rai Ajit K. Srivastava Ravi Jahagirdar Salman Azhar Somesh Sharma Charles L. Bisgaier | 2006 | Molecular and Cellular Biochemistry (-)2006，，1： | 1 |
| 9 | Mechanical properties of Fe-rich Si alloy from Hamiltonian显示文摘The physical origins of the mechanical properties of Fe-rich Si alloys are investigated by combining electronic structure calculations with statistical mechanics means such as the cluster variation method,molecular dynamics simulation,etc,applied to homogeneous and heterogeneous systems.Firstly,we examined the elastic properties based on electronic structure calculations in a homogeneous system and attributed the physical origin of the loss of ductility with increasing Si content to the combined effects of magneto-volume and D03 ordering.As a typical example of a heterogeneity forming a microstructure,we focus on grain boundaries,and segregation behavior of Si atoms is studied through high-precision electronic structure calculations.Two kinds of segregation sites are identified:looser and tighter sites.Depending on the site,different segregation mechanisms are revealed.Finally,the dislocation behavior in the Fe-Si alloy is investigated mainly by molecular dynamics simulations combined with electronic structure calculations.The solid-solution hardening and softening are interpreted in terms of two kinds of energy barriers for kink nucleation and migration on a screw dislocation line.Furthermore,the clue to the peculiar work hardening behavior is discussed based on kinetic Monte Carlo simulations by focusing on the preferential selection of slip planes triggered by kink nucleation. | Tetsuo Mohri Ying Chen Masanori Kohyama Shigenobu Ogata Arkapol Saengdeejing Somesh Kumar Bhattacharya Masato Wakeda Shuhei Shinzato Hajime Kimizuka | 2017 | npj Computational Materials2017，，1： | 1 |
| 10 | Resolution of Physical Signs and Recovery in Severe Cervical Spondylotic Myelopathy After Cervical Laminoplasty显示文摘 | Shankar Acharya Abhishek Srivastava Somesh Virmani Rushma Tandon | 2010 | Spine2010，，21： | 1 |
| 11 | Role of active efflux in association with target gene mutations in fluroquinolone resistance in clinical isolates of Vibrio cholerae显示文摘 | Somesh Baranwal Keya Dey T Ramamurthy | 2002 | Antimicrob agents and Chemoth2002，46，8： | 1 |
| 12 | EXECUTER2 modulates the EXECUTER1 signalosome through its singlet oxygen-dependent oxidation显示文摘Oxidative post-translational modifications of specific chloroplast proteins contribute to the initiation of retrograde signaling.The Arabidopsis thaliana EXECUTER1(EX1)protein,a chloroplast-localized singlet oxygen(^(1)O_(2))sensor,undergoes tryptophan(Trp)643 oxidation by^(1)O_(2),a chloroplast-derived and light-dependent reactive oxygen species.The indole side chain of Trp is vulnerable to^(1)O_(2),leading to the generation of oxidized Trp variants and priming EX1 for degradation by a membrane-bound FtsH protease.The perception of^(1)O_(2)via Trp643 oxidation and subsequent EX1 proteolysis facilitate chloroplast-to-nucleus retrograde signaling.In this study,we discovered that the EX1-like protein EX2 also undergoes^(1)O_(2)-dependent Trp530 oxidation and FtsH-dependent turnover,which attenuates^(1)O_(2)signaling by decelerating EX1-Trp643 oxidation and subsequent EX1 degradation.Consistent with this finding,the loss of EX2 function reinforces EX1-dependent retrograde signaling by accelerating EX1-Trp643 oxidation and subsequent EX1 proteolysis,whereas overexpression of EX2 produces molecular phenotypes opposite to those observed in the loss-of-function mutants of EX2.Intriguingly,phylogenetic analysis suggests that EX2 may have emerged evolutionarily to attenuate the sensitivity of EX1 toward^(1)O_(2).Collectively,these results suggest that EX2 functions as a negative regulator of the EX1 signalosome through its own^(1)O_(2)-dependent oxidation,providing a new mechanistic insight into the regulation of EX1-mediated^(1)O_(2)signaling. | Vivek Dogra Rahul Mohan Singh Mengping Li Mingyue Li Somesh Singh Chanhong Kim | 2022 | Molecular Plant2022，15，3： | 1 |
| 13 | Role of Active Ef- flux in Association with Target Gene Mutations in Fluoroquinolone Re- sistance in Clinical Isolates of Vibrio cholerae 显示文摘 | Somesh Baranwal Keya Dey T Ramamurthy | 2002 | Antimicrobial A- gents and Chemotherapy2002，46，8： | 1 |
| 14 | Molecular mechanisms controlling E-cadherin expression in breast cancer显示文摘 | Somesh Baranwal Suresh K. Alahari | 2009 | Biochemical and Biophysical Research Communications2009，，1： | 1 |
| 15 | Counterexample-Guided Abstraction Refinement for Symbolic Model Checking 显示文摘 | Edmund Clarke Orna Grumberg Somesh Jha | 2003 | Journal of the ACM (S0004-5411)2003，50，5： | 1 |
| 16 | Role of active cfflux in association with target gene muta- tions in fluoroquinolone resistance in clinical isolates of Vibrio cholerae 显示文摘 | BARANWAL Somesh DEY Keya RAMAMURTHY T | 2002 | Antimicrob agents and Chemoth J2002，46，8： | 1 |
| 17 | Verifying security protocols with Brutus显示文摘 | Marrero W Clarke Ed Somesh Jha | 2000 | ACM Transactions on Software Engineering and Methodology2000，9，4： | 1 |
| 18 | Genomic organization and expression profile of the small GTPases of the RhoBTB family in human and mouse显示文摘 | Ramos S Khademi F Somesh BP | 2002 | Gene2002，298，2： | 1 |
| 19 | Signal transduction pathways regulated by Rho GTPases in Dictyostelium 显示文摘 | Rivero F Somesh BP | 2002 | J Muscle Res Cell Motil2002，23，78： | 1 |
| 20 | Study of Hopfield neural network with sub-optimal and random GA for pattern recalling of English characters显示文摘 | Somesh Kumar Manu Pratap Singh | | 0，，08： | 1 |
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