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| 1 | Cardiac mucosa at the gastroesophageal junction:An Eastern perspective显示文摘AIM:To investigate the nature and origin of cardiac mucosa(CM).METHODS:Biopsy samples from sixty-one individuals were included in this study. The specimens were taken 'at','just below',or 'just above' the gastroesophageal junction,including the histologic squamocolumnar junction. Clinical data were obtained by reviewing electronic medical records for each patient. Patients with a history of stomach adenoma or carcinoma and esophageal carcinoma were excluded,and cases that were endoscopically suspicious of Barrett's esophagus or a polyp were also ruled out. Histologic and endoscopic reviews were performed blinded to the patient's clinical data. Histologic evaluation wasconducted by two pathologists,and endoscopic review was performed by a endoscopist with wide experience in the field. Histologically,the columnar epithelium of squamocolumnar junction,presence and severity of acute and chronic inflammation,atrophy,intestinal metaplasia,and presence of carditis were evaluated. Endoscopically,reflux esophagitis was evaluated by Los Angeles(LA) classification,hiatal hernias were classified by Hill grade,and gastroesophageal flap valves were assessed. RESULTS:Fifty-nine of the 61(96.7%) patients were Korean; 65.6%(40/61) of the patients underwent endoscopy according to the schedule of the National Health Insurance Program as a screening inspection. Of these,only 20.0%(8/40) of cases had reflux s y m p t o m s. C M w a s p r e s e n t i n 4 1 / 6 1( 6 7. 2 %) individuals,and its presence was associated with older age compared to oxyntocardiac mucosa/oxyntic mucosa(60.59 ± 2.02 years vs 51.55 ± 3.35 years; P = 0.018). The presence of CM was associated with endoscopic diagnosis of esophagitis according to the LA classification(P = 0.022). CM was associated with mononuclear cell infiltration and neutrophilic infiltration,which were statistically significant(P = 0.001,and P = 0.004,respectively). The inflammation of CM,'carditis',showed a statistically significant association with endoscopic diagnosis of reflux esophagitis according to the LA classification(P = 0.008). CONCLUSION:CM at the gastroesophageal junction is a common histologic finding in biopsy specimens,though not always present,and associated with gastroesophageal reflux disease and carditis severity. | Ahrong Kim Won-Young Park Nari Shin Hyun Jung Lee Young Keum Kim So Jeong Lee Cheong-Soo Hwang Do Youn Park Gwang Ha Kim Bong Eun Lee Hong-Jae Jo | 2015 | World Journal of Gastroenterology2015，21，30： | 2 |
| 2 | Lean mass and physical activity as predictors of bone mineral density in 16-20 years old women显示文摘 | Valdimarsson O Kristinsson JO Stefansson SO | 1999 | J Intern Med1999，245，5： | 1 |
| 3 | Prevalence of bacterial and candida albicans infection mongst women attending irrua specialist teaching hospital, irrua, nigeria 显示文摘 | ISIBOR JO SAMUEL SO NWAHAM CI | 2011 | Aft J Microbiol Res2011，5，20： | 1 |
| 4 | Exiting root injury in transforaminal endoscopic discectomy: preoperative im- age considerations for safety 显示文摘 | Choi I Ahn JO So WS | 2013 | Eur Spine J2013，22，11： | 1 |
| 5 | Reduced serum level of antibodies against amyloid beta peptide is associated with aging in Tg2576 mice显示文摘 | Sohn JH So JO Kim H | 2007 | Biochem Biophys Res Commun2007，361，3： | 1 |
| 6 | T h eA m erican C u sto m er S atisfactio n In dex: N ature, P u rp o se ,an d F in din gs 显示文摘 | F o rn e ll C Jo h n so n M D A n d e rso n E W | 1996 | Jou rn al o f M arketing1996，60，4： | 1 |
| 7 | Reduced serum level of antibodies against amyloid beta peptide is associated with aging in Tg2576 mice显示文摘 | So JO Kim H | 2007 | Biochem Biophys Res Commun2007，361，3： | 1 |
| 8 | Macrophages secrete matrix metalloproteinase 9 covalently linked to the core protein of chondroitin sulphate proteoglycans 显示文摘 | Winberg JO Kolset SO Berg E | 2000 | J Mol Biol2000，304，4： | 1 |
| 9 | Exiting root injury in transforaminal endoscopic discectomy: preoperative image considerations for safety 显示文摘 | Choi I Ahn JO So WS | 2013 | Eur Spine J2013，22，11： | 1 |
| 10 | Innate and adaptive immune responses in obliterative airway disease in rat tracheal allografts显示文摘 | Ropponen JO Syrj(a)l(a) SO Krebs R | | 0，，06： | 1 |
| 11 | Revisiting a neglected construct:parenting styles in a child-feeding context显示文摘 | Hughes SO Power TG Fisher JO | 2005 | Appetite2005，44，1： | 1 |
| 12 | Effects of Korean Red Ginseng ( Panax ginseng ), urushiol ( Rhus vernicifera Stokes), and probiotics ( Lactobacillus rhamnosus R0011 and Lactobacillus acidophilus R0052) on the gut–liver axis of alcoholic liver disease显示文摘 | Chang Seok Bang So Hyung Hong Ki Tae Suk Jin Bong Kim Sang Hak Han Hotaik Sung Eun Ji Kim Myoung Jo Kim Moon Young Kim Soon Koo Baik Dong Joon Kim | 2014 | Journal of Ginseng Research2014，，： | 1 |
| 13 | Lean mass and physical activity as predictors of bone mineral density in 16 - 20 years old women 显示文摘 | Kristinsson JO Stefansson SO | 1999 | J Intern Med1999，245，5： | 1 |
| 14 | Retention properties of fully integrated (Bi,La)4Ti3O12 capacitors and their lateral size effects显示文摘 | KIM D J JO J Y SO Y W | 2005 | Appl Phys Lett2005，86，02： | 1 |
| 15 | Some phar-macological studies on Morlnda luclda 显示文摘 | Awe SO Olajide OA Adeboye JO Makinde JM | 1998 | Indian J Pharmacol1998，30，： | 1 |
| 16 | Associations among parental feeding styles and children's food intake in families with limited incomes显示文摘 | Hoerr SL Hughes SO Fisher JO | 2009 | Int J Behav Nutr Phys Act2009，6，： | 1 |
| 17 | Insights into the evolutionary process of genome degradation 显示文摘 | Andersson JO Andersson SO | 1999 | Curr Opin Genet Dev1999，9，6： | 1 |
| 18 | Exiting root injury in trans foraminal endoscopic discectomy: preoperative image con siderations for safety显示文摘 | Choi I Ahn JO So WS | 2013 | Eur Spine J2013，22，24： | 1 |
| 19 | Physicochemical and functional properties of low DS cassava starch acetates and citrates显示文摘 | SO Agboola JO Akingbala | 1991 | Starch1991，，43： | 1 |
| 20 | Trajectories of heart failure self-care management and changes in quality of life 显示文摘 | Lee CS Mudd JO Hiatt SO | 2014 | Eur Cardiovasc Nurs2014，6，30： | 1 |
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