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| 1 | Treatment of gastric varices with partial splenic embolization in a patient with portal vein thrombosis and a myeloproliferative disorder显示文摘Therapeutic options for gastric variceal bleeding in the presence of extensive portal vein thrombosis associated with a myeloproliferative disorder are limited.We report a case of a young woman who presented with gastric variceal bleeding secondary to extensive splanchnic venous thrombosis due to a Janus kinase 2 mutation associated myeloproliferative disorder that was managed effectively with partial splenic embolization. | Robert Gianotti Hearns Charles Kenneth Hymes Hersh Chandarana Samuel Sigal | 2014 | World Journal of Gastroenterology2014，20，39： | 4 |
| 2 | Dominance network structure across reproductive contexts in the cooperatively breeding cichlid fish Neolamprologus pulcher显示文摘 | Cody J. DEY Q.Y. Joanne TAN Constance M. O'CONNOR Adam R. REDDON J. Ryan CALDWELL Sigal BALSHINE | 2015 | Current Zoology2015，61，1： | 4 |
| 3 | Glucagon-like peptide-1 reduces hepatic lipogenesis via activation of AMP-activated protein kinase显示文摘 | Shani Ben-Shlomo Isabel Zvibel Mati Shnell Amir Shlomai Elena Chepurko Zamir Halpern Nir Barzilai Ran Oren Sigal Fishman | 2010 | Journal of Hepatology2010，，6： | 3 |
| 4 | A Randomized, Prospective, Double-Blind, Placebo-Controlled Trial of Terlipressin for Type 1 Hepatorenal Syndrome显示文摘 | Arun J. Sanyal Thomas Boyer Guadalupe Garcia–Tsao Frederick Regenstein Lorenzo Rossaro Beate Appenrodt Andres Blei Veit Gülberg Samuel Sigal Peter Teuber | 2008 | Gastroenterology2008，，5： | 3 |
| 5 | Sequential capsule endoscopy of the small bowel for follow-up of patients with known Crohn’s disease显示文摘 | Eva Niv Sigal Fishman Helena Kachman Ruth Arnon Iris Dotan | 2014 | Journal of Crohn’s and Colitis2014，，： | 3 |
| 6 | Direct acting antiviral therapy is curative for chronic hepatitis C/autoimmune hepatitis overlap syndrome显示文摘Autoimmune phenomena are common in patients with chronic hepatitis C. Management of chronic hepatitis C/autoimmune hepatitis syndrome has until recently been problematic due to the adverse effects of interferon on autoimmune processes and immunosuppression on viral replication. In this report we describe 3 patients with chronic hepatitis C/autoimmune hepatitis overlap syndrome who responded rapidly to direct acting antiviral therapy. The resolution of the autoimmune process supports a direct viral role in its pathophysiology. | Farhad Sahebjam Cristina H Hajdu Esther Nortey Samuel H Sigal | 2016 | World Journal of Hepatology2016，8，14： | 2 |
| 7 | Operculina and Neoassilina:A Revision of Recent Nummulitid Genera Based on Molecular and Morphological Data Reveals a New Genus显示文摘The genus Operculina,a large symbiont-bearing benthic foraminifer,is characterized by high morphological variability showing thick involute to intermediate semi-involute to flat evolute tests.Different morphotypes are either considered as ecophenotypes or distinct species.In order to test the hypothesis of ecophenotypes versus different species,a single cell high throughput sequencing approach was applied to assess the interspecific diversity of Operculina.This results in two groups of ribotypes,one corresponding to Operculina ammonoides/Operculina discoidalis,the other containing Operculina complanata/Operculina elegans.These groups can also be separated morphologically.Therefore,O.complanata and O.elegans represent a single species and the latter can be regarded as a junior synonym of O.complanata.Operculina ammonoides and O.discoidalis also form a single species,which makes the latter a junior synonym of O.ammonoides.Because generic differences in Operculina species are manifested in morphology and molecular genetics,the genus Neoassilina with the designated species Neoassilina ammonoides is installed.Additional analysis of ribosomal SSU rDNA data of eight recent nummulitid genera confirms the obtained high troughput sequencing results and further shows that Palaeonummulites venosus builds a clade with O.complanata that branches at the base of other Nummulitidae containing Planostegina,Planoperculina,Cycloclypeus,Heterostegina,Operculinella and Neoassilina. | Maria Holzmann Johann Hohenegger Laure Apothéloz-Perret-Gentil Raphael Morard Sigal Abramovich Danna Titelboim Jan Pawlowski | 2022 | Journal of Earth Science2022，33，6： | 2 |
| 8 | Lipid phosphate phosphatases regulate lysophosphatidic acid production and signaling in platelets: studies using chemical inhibitors of lipid phosphate phosphatase activity显示文摘 | SMYTH S S SCIORRA V A SIGAL Y J | 2003 | J Biol Chem2003，278，43： | 2 |
| 9 | Increased fibrosis progression rates in hepatitis C patients carrying the prothrombin G20210A mutation显示文摘AIM: To examine whether hepatitis C virus (HCV)-infected patients who carry hypercoagulable mutationssuffer from increased rates of liver fi brosis. METHODS: We analyzed DNA samples of 168 HCV patients for three common hypercoagulable gene mutations: prothrombin 20210 (PT20210), factor V Leiden (FV Leiden) and methylene tetrahydrofolate reductase (MTHFR). The patients were consecutively recruited as part of the prospective 'Fibroscore Study' in France. The effect of the various mutations on the rate of fi-brosis was analyzed statistically and was correlated with epidemiological, clinical and biochemical data such as grade and stage of liver biopsies, patients' risk factors for liver cirrhosis, and timing of infection. RESULTS: Fifty two of the patients were categorized as 'fast fi brosers' and 116 as 'slow fi brosers'; 13% of the 'fast fi brosers' carried the PT20210 mutation as compared with 5.5% of the 'slow fi brosers', with an odds ratio of 4.76 (P = 0.033; 95% CI: 1.13-19.99) for 'fast' liver fibrosis. Carriage of MTHFR or FV Leiden mutations was not associated with enhanced liver fi brosis. CONCLUSION: Carriage of the PT20210 mutation is related to an increased rate of liver fi brosis in HCV patients. | Nitsan Maharshak Philippe Halfon Varda Deutsch Hava Peretz Shlomo Berliner Sigal Fishman Shira Zelber-Sagi Uri Rozovski Moshe Leshno Ran Oren | 2011 | World Journal of Gastroenterology2011，17，45： | 2 |
| 10 | A Randomized, Prospective, Double-Blind, Placebo-Controlled Trial of Terlipressin for Type 1 Hepatorenal Syndrome显示文摘 | Arun J. Sanyal Thomas Boyer Guadalupe Garcia–Tsao Frederick Regenstein Lorenzo Rossaro Beate Appenrodt Andres Blei Veit Gülberg Samuel Sigal Peter Teuber | 2008 | Gastroenterology2008，，5： | 2 |
| 11 | The effect of local attachment of cationized antioxidant enzymes on experimental colitis in the rat 显示文摘 | Sigal B Ron K Paul B | 2000 | Pharm Res2000，17，9： | 1 |
| 12 | Histopathology and clinical correlates of end-stage hepatitis B cirrhosis: a possible mechanism to ex- plain the response to antiviral therapy 显示文摘 | Sigal SH Ala A Ivanov K | 2005 | Liver Transpl2005，11，1： | 1 |
| 13 | Skin color-based video segmentation under time-varying illumination显示文摘 | Sigal L Sclaroff S Athitsos V | 2004 | IEEE Transactions on Pattern Analysis and Machine Intelligence2004，26，： | 1 |
| 14 | Risk factors associated with bus accident severity in the United States: A generalized ordered logit model 显示文摘 | Sigal Kaplan Carlo Giacomo Prato | 2012 | Journal of Safety Research2012，，43： | 1 |
| 15 | Hyponatremia in cirrhosis 显示文摘 | Sigal SH | 2012 | J Hosp Med2012，7，4： | 1 |
| 16 | Dynam- ics of the p53-Mdm2 feedback loop in individual cells 显示文摘 | LAHAV G ROSENFELD N SIGAL A | 2004 | Nature Genetics2004，36，2： | 1 |
| 17 | Codon 972 polymorphism in the insulinreceptor substrate-1 gene,obesity,and risk of noninsulin-dependent diabetes mellitus显示文摘 | SIGAL R J DORIA A WARRAM J H | 1996 | J Clin Endocrinol Metab1996，81，： | 1 |
| 18 | Physical activity/exercise and type 2 diabetes显示文摘 | Ronaldj Sigal | 2006 | Diabetes Care2006，29，6： | 1 |
| 19 | Skin color-based video segmentation under time-varying illumination显示文摘 | Leonid Sigal Stan Sclaroff | 2004 | IEEE Transactions on Pattern Analysis and Machine Intelligence2004，26，7： | 1 |
| 20 | Poliovirus pathogenesis in a new poliovirus receptor transgenic mouse model: age-dependent paralysis and a mucosalroute of infection显示文摘 | Crotty S Hix L Sigal L J | 2002 | J Clin Microbiol2002，83，7： | 1 |
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