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| 1 | Inflammatory bowel disease serology in Asia and the West显示文摘AIM:To study serological antibodies in Caucasians and Asians,in health and inflammatory bowel disease(IBD),in Australia and Hong Kong(HK).METHODS:Anti-glycan antibodies[anti-chitobioside(ACCA),anti-laminaribioside(ALCA)],and anti-mannobioside(AMCA),anti-Saccharomyces cervisiae(gASCA);and atypical perinuclear anti-neutrophil cytoplasmic antibody(pANCA)were tested in IBD patients,their unaffected relatives,and healthy controls in Australia and HK(China).Antibody status(positive or negative)and titre was compared between subjects of different geography,ethnicity and disease state.RESULTS:Ninety subjects were evaluated:21 Crohn’s disease(CD),32 ulcerative colitis(UC),29 healthy controls,and 8 IBD patient relatives.Forty eight subjects were Australian(29 Caucasian and 19 ethnic Han Chinese)and 42 were from HK(all Han Chinese).Caucasian CD patients had a significantly higher antibody prevalence of gASCA(67%vs 3%,P<0.001),ALCA(44%vs 6%,P=0.005),and AMCA(67%vs 15%,P=0.002),whereas HK CD patients had a higher prevalence of only AMCA(58%vs 25%,P=0.035),when compared with UC and healthy subjects in both countries.Caucasian CD had significantly higher gASCA prevalence(67%vs 0%,P<0.001)and titre(median59 vs 9,P=0.002)than HK CD patients.Prevalence and titres of ALCA,ACCA and AMCA did not differ between CD in the two countries.Presence of at least one antibody was higher in Caucasian than HK CD patients(100%vs 58%,P=0.045).pANCA did not differ between countries or ethnicity.CONCLUSION:Serologic CD responses differ between HK Asian and Australian Caucasian patients.Different genetic,environmental or disease pathogenic factors may account for these differences. | Lani Prideaux Michael A Kamm Peter De Cruz Daniel R van Langenberg Siew C Ng Iris Dotan | 2013 | World Journal of Gastroenterology2013，19，37： | 10 |
| 2 | Probiotics in inflammatory bowel disease: possible mechanisms of action显示文摘 | Iris Dotan Daniel Rachmilewitz | 2005 | Current Opinion in Gastroenterology2005，，4： | 4 |
| 3 | Sequential capsule endoscopy of the small bowel for follow-up of patients with known Crohn’s disease显示文摘 | Eva Niv Sigal Fishman Helena Kachman Ruth Arnon Iris Dotan | 2014 | Journal of Crohn’s and Colitis2014，，： | 3 |
| 4 | The second European evidence-based Consensus on the diagnosis and management of Crohn’s disease: Special situations显示文摘 | Gert Van Assche Axel Dignass Walter Reinisch C. Janneke van der Woude Andreas Sturm Martine De Vos Mario Guslandi Bas Oldenburg Iris Dotan Philippe Marteau Alessandro Ardizzone Daniel C. Baumgart Geert D’Haens Paolo Gionchetti Francisco Portela Boris Vuce | 2009 | Journal of Crohn’s and Colitis2009，，1： | 3 |
| 5 | Effect of different lens status on intraocular pressure elevation in patients treated with anti-vascular endothelial growth factor injections显示文摘AIM: To assess the effect of lens status on sustained intraocular pressure(IOP) elevation in patients treated intravitreally with anti-vascular endothelial growth factor(VEGF) agents. METHODS: Data were retrospectively collected for all patients treated with intravitreal injections of anti-VEGF medication at a tertiary medical center in July 2015. Findings were analyzed by lens status during 6 months' follow-up. The main outcome measure was a sustained increase in IOP(≥21 mm Hg or change of ≥6 mm Hg from baseline on ≥2 consecutive visits, or addition of a new IOPlowering medication during follow-up). RESULTS: A total of 119 eyes of 100 patients met the study criteria: 40 phakic, 40 pseudophakic, and 39 pseudophakic after Nd:YAG capsulotomy. The rate of sustained IOP elevation was significantly higher in the postcapsulotomy group(23.1%) than in the phakic/pseudophakic groups(8.1%;P=0.032), with no statistically significant differences among the 3 groups in mean number of injections, either total(P=0.82) or by type of anti-VEGF mediation(bevacizumab: P=0.19;ranibizumab: P=0.13), or mean follow-up time(P=0.70). CONCLUSION: Nd:YAG capsulotomy appears to be a risk factor for sustained IOP elevation in patients receiving intravitreal anti-VEGF injections. This finding has important implications given the growing use of anti-VEGF treatment and the irreversible effects of elevated IOP. | Amir Sternfeld Rita Ehrlich Dov Weinberger Assaf Dotan | 2020 | International Journal of Ophthalmology(English edition)2020，13，1： | 2 |
| 6 | 儿童有氧运动能力可训练性及相关问题显示文摘针对 Armstrong 最近关于'与青少年有氧能力相关的 10 个问题'的专题评论,再次对其提出的一些观点进行回顾,特别是儿童———成年人之间可训练差异性是否存在的问题·。讨论了许多现有的可得出可训练性结论的儿童 O_2max数据的有效性,为什么可训练性差异可能是一个事实而不是疑问,为解释这一现象所提供的一种合理的新方法,以及这种解释可以如何承担和回答其他几个提出的问题。本评论旨在激励并鼓励新的想法并提出建议,把注意力放在儿童的有氧可训练性上,还要更多地关注儿童运动生理学和表现以及他们与成年人的不同之处。 | Raffy Dotan 朱为模 | 2018 | 体育科研2018，39，2： | 2 |
| 7 | Scleral cross-linking using riboflavin and ultraviolet-A radiation for prevention of progressive myopia in a rabbit model显示文摘 | Dotan A Kremer I Livnat T | 2014 | Exp Eye Res2014，127，： | 1 |
| 8 | Positive surgical margins in soft tissue following radical cysteetomy for bladder cancer and cancer specific survival 显示文摘 | DOTAN ZA KAVANAGH K YOSSEPOWITCH O | 2007 | J Urol2007，178，6： | 1 |
| 9 | Circulating tumor cells: evolving evidence and future ehallenges显示文摘 | Dotan E Cohen SJ Alpaugh KR | 2009 | Oncologist2009，14，11： | 1 |
| 10 | Correlation clustering in general weighted graphs显示文摘 | Erik D. Demaine Dotan Emanuel Amos Fiat Nicole Immorlica | 2006 | Theoretical Computer Science2006，，2： | 1 |
| 11 | Progression of diabetic retinopathy after cataract extraction 显示文摘 | Pollack A Dotan S Oliver M | 1991 | Br J Ophthamol1991，75，9： | 1 |
| 12 | Hydrophobic and self-cleaning coatings显示文摘 | Dodiuk H Rios P F Dotan A | 2007 | Polymers for Advanced Technologies2007，18，19： | 1 |
| 13 | The seventh layer of the clinical-genomics information infrastructure显示文摘 | Shabo A Dotan D | 2007 | IBM System Journal2007，46，1： | 1 |
| 14 | Effects of IL-1 molecules on growth patterns of 3-MCA-induced cell lines: an interplay between im- munogenicity and invasive potential 显示文摘 | Vomnov E Reich E Dotan S | 2010 | J Immunotoxicol2010，7，1： | 1 |
| 15 | Scleral cross-linking using riboflavin and ultraviolet-a radiation for prevention of progressive myopia in a rabbit model显示文摘 | Dotan A Kremer I Livnat T | 2014 | Exp Eye Res2014，127，： | 1 |
| 16 | Defining optimal therapy for muscle invasive bladder cancer显示文摘 | Herr H W Dotan Z Donat S M | 2007 | Journal of Urology2007，177，： | 1 |
| 17 | Combined pars plana vitrectomy and cataract surgery: outcome of phacoemulsification versus manual extracapsular cataract extraction through a sclerocorneal tunnel 显示文摘 | Axer-Siegel R Dotan G Rosenblatt I | 2006 | Ophthalmic Surg Lasers Imaging2006，37，2： | 1 |
| 18 | Control of Colletotrichum acutatum in strawberry under laboratory, greenhouse, and field conditions显示文摘 | Freeman S Nizani Y Dotan S | 1997 | Plant Disease1997，81，： | 1 |
| 19 | The role of IL-l显示文摘 | Carmi Y Dotan S Rider P | 2013 | J Immunol2013，190，7： | 1 |
| 20 | Aduh genitourinary sarcoma: the 25-year Memorial Sloan-Kettering experience 显示文摘 | Dotan ZA Tal R Golijanin D | 2006 | J Urol2006，176，5： | 1 |
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