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| 1 | 早产儿视网膜病变早期治疗(ETROP)过程中发生视网膜脱离眼的预后显示文摘研究对象:在早产儿视网膜病变早期治疗(ETROP)研究中因早产儿视网膜病变(ROP)而发生视网膜脱离眼的结构以及功能改变。
研究方法:加入ETROP研究中的新生儿患有双眼高危阈前ROP,随即对其一眼进行早期治疗,另一眼进行传统治疗。只有单眼患病的早产儿。随机对高危阈前ROP眼进行早期治疗或传统治疗。当视网膜脱离被发现时。研究者会继续观察患者病变或对其行视网膜玻璃体手术(如巩膜加压术以肜或者玻璃体切除术)。在矫正9月龄时,对患者视网膜状况进行评估并使用条栅视敏度(grating acuity)对患儿视力进行检测。
研究结果:401例高危阈前ROP患者加入了ETROP研究。63例患者(89只眼)发生了视网膜脱离。对其中56例患者(78只眼)进行了随访。21例患者(38%)的视网膜脱离发生于双眼。其中30只眼分级为4A,14只眼为4B,16只眼为5级。余下的18只视网膜脱离眼未进行分级。对11例患者(12只眼)监控病情变化,52例患者(66只眼)行玻璃体视网膜手术。行玻璃体切除伴或不伴有巩膜加压术的56只眼中有17只(30%)在患者9月龄时保持或达到了黄斑复位;仅行巩膜加压术的10只眼中,6只(60%)达到;未行手术的12只眼中,2只(17%)达到。78只眼中有13只(17%)达到了较好的视力水平(I〉1.85cycles/degree)。达到正常视力水平(≥3.70cycles/degree)的6只眼的视网膜脱离分级均为4A(其分别为6只未行手术眼中的1眼,6只行巩膜加压术眼中的3眼。18只行玻璃体切除术眼中的2眼)。对11只视网膜脱离达5级的患眼行玻璃体视网膜手术。
治疗结果为6只眼无光感,3只眼仅有光感,2只眼只能看清低视力表。结论:在ETROP的研究中,ROP导致视网膜脱离的治疗结果普遍较差。因视网膜脱离行玻璃体视网膜手术的48只眼中,有16只眼黄斑未发生脱离。手术修复4A级视网膜脱离的24只眼中,有5只(21%)在术后达到了正常视力水平。对视网膜脱离5级眼行玻璃体视网膜手术可以使其达到结构复位,但功能恢复不佳。 | Michael X. Repka Betty Tung William V. Good Michael Shapiro Antonio Capone Jr John D. Baker Charles C. Barr Dale L. Phelps W. A. J. van HewvenMD John D. Baker,MD Charles C. Barr,MD Dale L. Phelps,MD IV. A. J. van Heuven 张弛(译) | 2006 | 美国医学会眼科杂志(中文版)2006，18，3： | 4 |
| 2 | Thoracoscopic segmentectomy compares favorably with thoracoscopic lobectomy for patients with small stage I lung cancer显示文摘 | Mark Shapiro Todd S. Weiser Juan P. Wisnivesky Cynthia Chin Michael Arustamyan Scott J. Swanson | 2009 | The Journal of Thoracic and Cardiovascular Surgery2009，，6： | 3 |
| 3 | In Vivo Clonal Analysis Reveals Self-Renewing and Multipotent Adult Neural Stem Cell Characteristics显示文摘 | Michael A. Bonaguidi Michael A. Wheeler Jason S. Shapiro Ryan P. Stadel Gerald J. Sun Guo-li Ming Hongjun Song | 2011 | Cell2011，，7： | 2 |
| 4 | Hepatitis B vaccination in patients with inflammatory bowel disease显示文摘AIM:To determine the prevalence for hepatitis B virus(HBV) and HBV screening and vaccination practices for inflammatory bowel disease(IBD).METHODS:This study is a retrospective,cross-sectional observational study.A retrospective chart review was performed in 500 patients who have been consecutively treated for IBD between September 2008 and January 2013 at the Rush University Medical Center Gastroenterology section.The patients were identified through the electronic medical record with the criteria that they attended the gastroenterology clinic,and that they had a diagnosis of IBD at the time of visit discharge.Once identified,each record was analyzed to determine whether the subject had been infected with HBV in the past,already been vaccinated against HBV,or advised to get vaccinated and followed through with the recommended vaccination.RESULTS:About 254 out of 500 patients(51%) had HBV screening ordered.Among those ordered to have screening tests,86% followed through with HBV serology.Gastroenterology physicians had significantly different screening ratios from each other(P < 0.001).There were no significant differences in the ratios of HBV screening when IBD specialists were compared to other gastroenterology physicians(0.505 ± 0.023 vs 0.536 ± 0.066,P = 0.66).Of those 220 patients screened,51% of IBD patients were found not to be immune against HBV.Approximately 50% of gastroenterology physicians recommended HBV vaccinations to their patients in whom serology was negative for antibodies against HBV.IBD specialists recommended vaccinations to a higher percentage of their patients compared to other gastroenterology physicians(0.168 ± 0.019 vs 0.038 ± 0.026,P = 0.015).Present and/or past HBV infection was found in 3.6% of the patients who had serology checked.There was no statistically significant difference in the prevalence of hepatitis B surface antigen(HBsAg) between our study and that reported in previous studies done in Spain(4/220 vs 14/2076 respectively,P = 0.070); and in France(4/220 vs 3/315 respectively,P = 0.159).But,the prevalence of anti-HBcAb in this study was less than that reported in the study in Spain(7/220 vs 155/2076 respectively,P = 0.006); and was not sig-nificantly different from that reported in the study in France(7/220 vs 8/315 respectively,P = 0.313).CONCLUSION:The prevalence of HBsAg in our IBD patients was not higher than previously reported European studies.Most IBD patients are not routinely screened or vaccinated against HBV at a tertiary referral center in the United States. | Ruwaida Ben Musa Anuhya Gampa Sanjib Basu Ali Keshavarzian Garth Swanson Michael Brown Rana Abraham Keith Bruninga John Losurdo Mark DeMeo Sohrab Mobarhan David Shapiro Ece Mutlu | 2014 | World Journal of Gastroenterology2014，20，41： | 2 |
| 5 | Current Status of Gastrointestinal Carcinoids显示文摘 | Irvin M. Modlin Mark Kidd Igor Latich Michelle N. Zikusoka Michael D. Shapiro | 2005 | Gastroenterology2005，，6： | 2 |
| 6 | A multiscale random field model for Bayesian image segmentation显示文摘 | Shapiro Michael | 1994 | IEEE Trans Image Processing1994，3，： | 1 |
| 7 | Cardiac Magnetic Resonance With T2-Weighted Imaging Improves Detection of Patients With Acute Coronary Syndrome in the Emergency Department显示文摘 | Ricardo C. Cury Khalid Shash John T. Nagurney Guido Rosito Michael D. Shapiro Cesar H. Nomura Suhny Abbara Fabian Bamberg Maros Ferencik Ehud J. Schmidt David F. Brown Udo Hoffmann Thomas J. Brady | 2008 | Circulation2008，，8： | 1 |
| 8 | Technology adop- tion in the presence of network externalities显示文摘 | KATZ MICHAEL CARL SHAPIRO | 1986 | Journal of Political Economy1986，94，4： | 1 |
| 9 | Feature-based correspondence:an eigenvector approach显示文摘 | Larry S Shapiro J Michael Brady | 1992 | Image and Vision Computing1992，10，： | 1 |
| 10 | Network externalities, competitionand compatibility 显示文摘 | Michael K L Shapiro C | 1985 | American Economic Review1985，75，： | 1 |
| 11 | Technology adoption in the presence of network externalities 显示文摘 | Katz Michael Carl Shapiro | 1985 | Journal of Political E conomy1985，94，： | 1 |
| 12 | Fabrication and cold test of photonic band gap resonators and accelerator structures显示文摘 | Smirnova Evgenya I Mastovsky Ivan Shapiro Michael A | 2005 | Phys Rev ST AB2005，8，09： | 1 |
| 13 | Technology Adoption in the Presence of Network Externalities 显示文摘 | Katz Michael Carl Shapiro | 1985 | Journal of Political Economy1985，94，： | 1 |
| 14 | Technology adoption in the presence of network externalities 显示文摘 | Katz Michael Carl Shapiro | 1985 | Journal of Political Economy1985，94，： | 1 |
| 15 | Technology adoption in the presence of network externalities显示文摘 | Katz Michael Carl Shapiro | 1985 | Journal of Political Economy1985，94，： | 1 |
| 16 | Technology adoption in the presence of network externalities 显示文摘 | Katz Michael Carl Shapiro | 1985 | Journal of Political Economy1985，94，： | 1 |
| 17 | Technology adoption in the presence of network externalities 显示文摘 | Katz Michael Carl Shapiro | 1985 | Journal of Political E- conomy1985，94，： | 1 |
| 18 | Systems competition and network effects显示文摘 | Katz Michael Shapiro C | 1994 | Journal of Economic Perspectives1994，，8： | 1 |
| 19 | Technology adoption in the presence of network externalities 显示文摘 | Katz Michael Carl Shapiro | 1985 | Journal of Political Economy1985，94，： | 1 |
| 20 | Serious Complications Within 30 Days of Screening and Surveillance Colonoscopy Are Uncommon显示文摘 | Cynthia W. Ko Stacy Riffle Leann Michaels Cynthia Morris Jennifer Holub Jean A. Shapiro Marcia A. Ciol Michael B. Kimmey Laura C. Seeff David Lieberman | 2010 | Clinical Gastroenterology and Hepatology2010，，： | 1 |
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