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3篇 您的检索式:作者名="Shahrukh Hashmi"
    题名 作者 年代 出处 被引量
1Successful amelioration of oxaliplatin -induced hyperexcitabilitysyndrome with the antiepileptic pregabalin in a patientwith pancreatic cancer 显示文摘Muhammad Wasif Saif Shahrukh Hashmi 2008Cancer Chemother Phannacol2008,61,:1
2Maternal fever during early pregnancy and the riskof oral clefts显示文摘Shahrukh Hashmi S Gallaway MS Waller DK 0,,03:1
3Therapy-related myeloid neoplasms - what have we learned so far?显示文摘Therapy-related myeloid neoplasms are neoplastic processes arising as a result of chemotherapy, radiation therapy, or a combination of these modalities given for a primary condition. The disease biology varies based on the etiology and treatment modalities patients receive for their primary condition. Topoisomerase Ⅱ inhibitor therapy results in balanced translocations. Alkylating agents, characteristically, give rise to more complex karyotypes and mutations in p53. Other etiologies include radiation therapy, high-dose chemotherapy with autologous stem cell transplantation and telomere dysfunction. Poor-risk cytogenetic abnormalities are more prevalent than they are in de novo leukemias and the prognosis of these patients is uniformly dismal. Outcome varies according to cytogenetic risk group. Treatment recommendations should be based on performance status and karyotype. An in-depth understanding of risk factors that lead to the development of therapyrelated myeloid neoplasms would help developing riskadapted treatment protocols and monitoring patients after treatment for the primary condition, translating into reduced incidence, early detection and timely treatment.Mohammad Faizan Zahid Aric Parnes Bipin N Savani Mark R Litzow Shahrukh K Hashmi 2016World Journal of Stem Cells2016,8,8:0
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