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| 1 | 胆道肿瘤临床实践指南(英文第三版)显示文摘日本肝胆胰外科学会(JSHBPS)于2007年出版第一版胆道肿瘤(胆管癌、胆囊癌及壶腹癌)临床实践指南,于2014年更新第二版,2021年英文第三版胆道肿瘤临床实践指南围绕6个主题提出若干临床问题,基于相关循证医学证据并组织专家讨论后,最终确定推荐意见、推荐强度以及推荐说明。根据证据推荐分级的评估、制订与评价(GRADE)系统,推荐强度被分为1级(强)或者2级(弱)。英文第三版胆道肿瘤临床实践指南中提出的31个临床问题涵盖:(1)预防性治疗;(2)诊断;(3)胆道引流;(4)外科治疗;(5)化疗;(6)放疗。31个临床问题中,14个问题给予推荐强度为强的推荐意见,14个问题给予推荐强度为弱的推荐意见,剩余的3个问题未给予推荐意见。每条推荐意见都进行推荐强度说明。最新版指南基于循证医学证据,为临床提供了重要建议。未来与癌症登记数据库协作将是评估指南和建立新证据的关键。 | Masato Nagino Satoshi Hirano Hideyuki Yoshitomi Taku Aoki Katsuhiko Uesaka Michiaki Unno Tomoki Ebata Masaru Konishi Keiji Sano Kazuaki Shimada Hiroaki Shimizu Ryota Higuchi Toshifumi Wakai Hiroyuki Isayama Takuji Okusaka Toshio Tsuyuguchi Yoshiki Hirooka Junji Furuse Hiroyuki Maguchi Kojiro Suzuki Hideya Yamazaki Hiroshi Kijima Akio Yanagisawa Masahiro Yoshida Yukihiro Yokoyama Takashi Mizuno Itaru Endo 杨翼飞(译) 仇毓东(译) 赵梦珂(译) 伏旭(译) 蔡正华(译) 毛凉(审校) | 2021 | 中华消化外科杂志2021，20，4： | 7 |
| 2 | Bile duct hamartomas(von Mayenburg complexes) mimicking liver metastases from bile duct cancer:MRC findings显示文摘我们在场是的有胆总管癌症的一个 72 岁的人的一个盒子开始相信了吃多重肝转移基于计算断层摄影术调查结果,并且在磁性的回声胆管造影术(MRC ) 在谁揭示胆汁管 hamartomas 的诊断。在为 pancreaticoduodenectomy 的探索,肝触诊在肝的表面揭示了传播小瘤。这些小瘤在在两片肝脑叶的表面上散布的直径显示出大约 0.5 厘米的灰色白人的榴状的损害,它被看起来像从胆汁管癌的多重肝转移。肝活体检视的冰冻切片揭示了多重胆汁管,稍微扩大的腔在多重胆汁管 hamartomas (BDH ) 的成胶的基质特征嵌入。仅仅二份报告描述了胆汁管 hamartomas 的 MRC 特征。所有成像过程, MRC 为胆汁管 hamartomas 的成像诊断提供最相关的特征。 | Yasuhiko Nagano Kenichi Matsuo Katsuya Gorai Kazuya Sugimori Chikara Kunisaki Hideyuki Ike Katsuaki Tanaka Toshio Imada Hiroshi Shimada | 2006 | World Journal of Gastroenterology2006，12，8： | 4 |
| 3 | Rescue of white egg 1 mutant by introduction of the wildtype Bombyx kynurenine 3-monooxygenase gene显示文摘在蚕,白鸡蛋 1 (w-1 ) 异种,被白眼睛和白鸡蛋描绘,在 Bombyx kynurenine 3-monooxygenase (KMO ) 是缺乏的活动。Toinvestigate w-1 异种显型是否被介绍野类型的 KMO 基因救,我们在细胞质的肌动朊基因倡导者(A3KMO ) 或本国的 KMO 基因倡导者(KKMO ) 的控制下面与野类型的 Bombyx KMO 基因构造了转基因的蚕。我们与 KKMO 构造与 A3KMO 和一根线创造了二根转基因的线。在这些线的成年人的眼睛是棕色的,并且转基因的女性生的鸡蛋也是棕色的。Reversetranscription 聚合酶链反应(RT-PCR ) 分析证明 A3KMO 蚕线在中间勇气的、胖身体表示了抄本,并且肾小体小管。KKMO 线仅仅在胖身体表示了抄本并且肾小体小管。在转基因的线的眼睛和卵色的紧张与 KMO 表示水平成正比。有趣地,有 A3KMO 构造的转基因的幼虫有轻褐幼虫的表皮,而是 KKMO 线不。这些结果显示野类型的 KMO 基因能作为标记基因被使用视觉上屏蔽转基因的蚕。 | GUO-XING QUAN ISAO KOBAYASHI KATSURA KOJIMA KEIRO UCHINO TOSHIO KANDA HIDEKI SEZUTSU TORU SHIMADA TOSHIKI TAMURA | 2007 | Insect Science2007，14，2： | 4 |
| 4 | Levovist ultrasonography imaging in intracystic hemorrhage of simple liver cyst显示文摘The differential diagnosis between intracystic hemorrhage and cystadenocarcinoma of the liver is often difficult even with the use of various imaging modalities. A 73-year-old woman was admitted to our hospital with the complaint of right upper quadrant pain. Ultrasonography (US) demonstrated a heterogeneous echogenic cyst measuring 11 cm × 8 cm in size in S2 of the liver, indicated intracystic hemorrhage of simple liver cyst or cystadenocarcinoma, but the differential diagnosis was considerably difficult. Levovist (Schering, Berlin, Germany) US revealed no enhancement of the intracystic structures, suggesting a clot in the case of intracystic hemorrhage. An operation was performed and the resected lesion showed a solitary benign liver cyst, measuring 5.5 cm × 4.7 cm × 8.5 cm containing a large blood clot. The patient had an uneventful recovery after the surgery. Levovist US may play an important role in discrimination between intracystic hemorrhage of simple hepatic cysts and cystadenocarcinoma of the liver. | Tomoyuki Akiyama Masahiko Inamori Satoru Saito Hirokazu Takahashi Masato Yoneda Koji Fujita Toshio Fujisawa Yasunobu Abe Hiroyuki Kirikoshi Kensuke Kubota Michio Ueda Kuniya Tanaka Shinji Togo Norio Ueno Hiroshi Shimada Atsushi Nakajima | 2008 | World Journal of Gastroenterology2008，14，5： | 4 |
| 5 | Morning Surge in Blood Pressure as a Predictor of Silent and Clinical Cerebrovascular Disease in Elderly Hypertensives: A Prospective Study显示文摘 | Kazuomi Kario Thomas G. Pickering Yuji Umeda Satoshi Hoshide Yoko Hoshide Masato Morinari Mitsunobu Murata Toshio Kuroda Joseph E. Schwartz Kazuyuki Shimada | 2003 | Circulation: Journal of the American Heart Association2003，，10： | 3 |
| 6 | Contrast-enhanced sonography of pancreatic carcinoma: correlations with pathological findings显示文摘 | Kazushi Numata Yutaka Ozawa Noritoshi Kobayashi Toru Kubota Hiroshi Shimada Akinori Nozawa Yukio Nakatani Kazuya Sugimori Kenichi Matsuo Toshio Imada Katsuaki Tanaka | 2005 | Journal of Gastroenterology2005，，6： | 2 |
| 7 | A cluster of genes encodes the two types of chalcone isomerase involved in the biosynthesis of general falavonoids and legume-specific 5-deoxy(iso) Flavonoids in Lotus japonicus显示文摘 | Toshio Aoki Shusei Sato | 2003 | Plant Physiology2003，131，3： | 1 |
| 8 | High Plasma Brain Natriuretic Polypeptide Level as a Marker of Risk for Thromboembolism in Patients With Nonvalvular Atrial Fibrillation显示文摘 | Hiromi Shimizu Yo Murakami Shin-ichi Inoue Yoko Ohta Ko Nakamura Harumi Katoh Takeshi Sakne Nobuyuki Takahashi Shuzo Ohata Takashi Sugamori Yutaka Ishibashi Toshio Shimada | 2002 | Stroke: Journal of the American Heart Association2002，，4： | 1 |
| 9 | Diagnosis of cardiac sarcoidosis and evaluation of the effects of steroid therapy by gadolinium-DTPA–enhanced magnetic resonance imaging显示文摘 | Toshio Shimada Kazue Shimada Takeshi Sakane Koichi Ochiai Hironori Tsukihashi Motonari Fukui Shin-ichi Inoue Harumi Katoh Yo Murakami Yutaka Ishibashi Riruke Maruyama | 2001 | The American Journal of Medicine2001，，： | 1 |
| 10 | Energy and environmental effective combustion with regenerative burners 显示文摘 | Toshio Shimada | 1997 | Scandinavian journal of metallurgy1997，26，： | 1 |
| 11 | Myocarditis and Heart Failure Associated With Hepatitis C Virus Infection显示文摘 | Akira Matsumori Toshio Shimada Nora M. Chapman Steven M. Tracy Jay W. Mason | 2006 | Journal of Cardiac Failure2006，，4： | 1 |
| 12 | Feasibility of Rotary Cup Atomizer for Slag Granulation显示文摘 | Toshio Mizuochi Tomohiro Akiyama Taihei Shimada | 2001 | ISIJ International2001，41，12： | 1 |
| 13 | Tumor Budding as a Strong Prognostic Indicator in Invasive Ampullary Adenocarcinomas显示文摘 | Nobuyuki Ohike Ipek Coban Grace E. Kim Olca Basturk Takuma Tajiri Alyssa Krasinskas Sudeshna Bandyopadhyay Toshio Morohoshi Yuki Shimada David A. Kooby Charles A. Staley Michael Goodman Nazmi Volkan Adsay | 2010 | The American Journal of Surgical Pathology2010，，10： | 1 |
| 14 | Morning Surge in Blood Pressure as a Predictor of Silent and Clinical Cerebrovascular Disease in Elderly Hypertensives: A Prospective Study显示文摘 | Kazuomi Kario Thomas G. Pickering Yuji Umeda Satoshi Hoshide Yoko Hoshide Masato Morinari Mitsunobu Murata Toshio Kuroda Joseph E. Schwartz Kazuyuki Shimada | 2003 | Circulation: Journal of the American Heart Association2003，，10： | 1 |
| 15 | The effect of hypertension, agingand benidipine on arterial elastic- ity in elderly hypertensives显示文摘 | Tetsuhiro Umeno Toshio Shimada Hironori Tsukihashi | 2010 | CVD Prevention and Control2010，5，2： | 1 |
| 16 | Feasibility of Rotary Cup Atomizer for Slag Granulation显示文摘 | Toshio Mizuochi Tomohiro Akiyama Taihei Shimada | | 0，，12： | 1 |
| 17 | Phenotypic and genotypic characteristics and epidemiological significance of ctx-strains of Vibrio cholerae isolated from seafood in malaysia显示文摘 | Chen CH Toshio Shimada Nasreldin E | 2004 | Appl Environ Microbiol2004，70，： | 1 |
| 18 | A cluster of genes encodes the two types of chalcone isomerase involved in the biosynthesis of general falavonoids and legume-specifics-deoxy(iso)Flavonoids in Lotus japonicas显示文摘 | Norimoto Shimada Toshio Aoki Shusei Sato | 2003 | Plant Physiology2003，131，3： | 1 |
| 19 | High Plasma Brain Natriuretic Polypeptide Level as a Marker of Risk for Thromboembolism in Patients With Nonvalvular Atrial Fibrillation显示文摘 | Hiromi Shimizu Yo Murakami Shin-ichi Inoue Yoko Ohta Ko Nakamura Harumi Katoh Takeshi Sakne Nobuyuki Takahashi Shuzo Ohata Takashi Sugamori Yutaka Ishibashi Toshio Shimada | 2002 | Stroke: Journal of the American Heart Association2002，，4： | 1 |
| 20 | High Plasma Brain Natriuretic Polypeptide Level as a Marker of Risk for Thromboembolism in Patients With Nonvalvular Atrial Fibrillation显示文摘 | Hiromi Shimizu Yo Murakami Shin-ichi Inoue Yoko Ohta Ko Nakamura Harumi Katoh Takeshi Sakne Nobuyuki Takahashi Shuzo Ohata Takashi Sugamori Yutaka Ishibashi Toshio Shimada | 2002 | Stroke: Journal of the American Heart Association2002，，4： | 1 |
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