|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Management of pancreaticobiliary disease using a new intra-ductal endoscope:The Texas experience显示文摘AIM:To evaluate a new single-operator mini-endoscope, Spyglass,for its performance,feasibility and safety in the management of pancreaticobiliary disease. METHODS:In a multicenter retrospective analysis of patients undergoing intraductal endoscopy,we evaluated 128 patients(71 men,mean age 57.6 years).Indications were therapeutic(TX)in 72(56%) and diagnostic(DX)in 56(44%). RESULTS:Peroral endoscopy was performed in 121 and percutaneous in seven.TX indications included CBD stones in 41,PD stones in six,and biliary strictures in 25.DX indications included abnormal LFT’s in 15, abnormal imaging in 38 and cholangiocarcinoma staging in three.Visualization of the stone(s)was considered good in 31,fair in six,and poor in four. Advancement of the electrohydraulic lithotripsy probe was not possible in three patients and proper targeting of the lesion was partial in four patients.A holmium laser was used successfully in three patients.Ductal clearance was achieved in 37 patients after one procedure and in four patients after two procedures.Diagnosis of biliary strictures was modified in 20/29 and confirmed to be malignant in 10/23.Of the modified patients,no diagnosis was available in 17.Spyglass demonstrated malignancy in 8/17 and non-malignancy in nine.Suspected pathology by imaging studies and abnormal LFT’s was modified in 43/63(66%).Staging of cholangiocarcinoma demonstrated multicentric cholangiocarcinoma in 2/3.There was no morbidity associated with the use of Spyglass. CONCLUSION:Spyglass Spyscopeis a first generation, single operator miniature endoscope that can evaluate and treat various biliary and pancreatic tract diseases. | Douglas S Fishman Paul R Tarnasky Sandeep N Patel Isaac Raijman | 2009 | World Journal of Gastroenterology2009，15，11： | 22 |
| 2 | Over expression of resistin in adipose tissue of the obese induces insulin resistance显示文摘AIM: To compare resistin mRNA expression in subcutaneous adipose tissue (SAT) and its correlation with insulin resistance (IR) in postmenopausal obese women. METHODS: A total of 68 postmenopausal women (non obese = 34 and obese = 34) were enrolled for the study. The women of the two groups were age matched (49-70 years). Fasting blood samples were collected at admission and abdominal SAT was obtained during surgery for gall bladder stones or hysterectomy. Physical parameters [age, height, weight, body mass index (BMI)] were measured. Biochemical (plasma insulin and plasma glucose) parameters were estimated by enzymatic methods. RNA was isolated by the Trizol method.SAT resistin mRNA expression was done by real time- reverse transcription polymerase chain reaction (RT-PCR) by using Quanti Tect SYBR Green RT-PCR master mix. Data was analyzed using independent Student's t test, correlation and simple linear regression analysis. RESULTS: The mean weight (52.81 ± 8.04 kg vs 79.56 ± 9.91 kg; P < 0.001), BMI (20.23 ± 3.05 kg/m 2 vs 32.19 ± 4.86 kg/m 2 ; P < 0.001), insulin (8.47 ± 3.24 U/mL vs 14.67 ± 2.18 U/mL; P < 0.001), glucose (97.44 ± 11.31 mg/dL vs 109.67 ± 8.02 mg/dL; P < 0.001) and homeostasis model assessment index (2.01 ± 0.73 vs 3.96 ± 0.61; P < 0.001) were significantly higher in postmenopausal obese women compared to postmenopausal non obese women. The mean serum resistin level was also significantly higher in postmeno-pausal obese women compared to postmenopausal non obese women (9.05 ± 5.15 vs 13.92 ± 6.32, P < 0.001). Furthermore, the mean SAT resistin mRNA expression was also significantly (0.023 ± 0.008 vs 0.036 ± 0.009; P < 0.001) higher and over expressed 1.62 fold (upregulated) in postmenopausal obese women compared to postmenopausal non obese women. In postmeno-pausal obese women, the relative SAT resistin mRNA expression showed positive (direct) and significant correlation with BMI (r = 0.78, P < 0.001) and serum resistin (r = 0.76, P < 0.001). Furthermore, the SAT resistin mRNA expression in postmenopausal obese women also showed significant and direct association (r = 0.45, P < 0.01) with IR, while in postmenopausal non obese women it did not show any association (r = -0.04, P > 0.05). CONCLUSION: Increased SAT resistin mRNA expres-sion probably leads to inducing insulin resistance and thus may be associated with obesity-related disorders in postmenopausal obese women. | Sadashiv Sunita Tiwari S Dhananjai Bhola N Paul Sandeep Kumar Abhijit Chandra Mahendra PS Negi | 2012 | World Journal of Diabetes2012，3，7： | 10 |
| 3 | 反相高效液相色谱法同时检测片剂中的头孢呋辛酯及奥硝唑(英文)显示文摘A simple,accurate and sensitive reversed-phase high performance liquid chromatographic(RP-HPLC)method for the simultaneous determination of cefuroxime axetil and ornidazole in combined tablet dosage form has been developed.The method was performed with a HiQ-SiL C18 column(250 mm×4.6 mm)and photodiode array(PDA)detector,using 0.01 mol/L potassium dihydrogen orthophosphate-methanol(56∶44,v/v)as the mobile phase and tinidazole as the internal standard.Beer's law obeys in the concentration ranges of 5-25 μg/mL and 10-50 μg/mL for cefuroxime axetil and ornidazole,respectively.The method has been successfully validated statistically and applied for the analysis of the drugs in pharmaceutical formulation. | RANJANE Poonam N GANDHI Santosh V KADUKAR Sayali S RANHER Sandeep S | 2008 | 色谱2008，26，6： | 4 |
| 4 | myocardial 以后梗塞巨人让室的 pseudoaneurysm 与严重的心失败介绍显示文摘 Left ventricle(LV) pseudoaneurysm is a late mechanical complication of myocardial infarction.A giant LV pseudoaneurysm is a rare presentation.We report a case of giant LV pseudoaneurysm in a post-MI patient who presented with gross congestive heart failure.The patient had a successful surgical repair of the aneurysm and had a favorable 3-mo outcome.The imaging modality and surgical treatment of the pseudoaneurysm are discussed. | Rajesh Vijayvergiya Alok Kumar Sandeep S Rana Harkant Singh Goverdhan D Puri Manphool Singhal | 2012 | World Journal of Cardiology2012，4，11： | 3 |
| 5 | The role of serotonin receptor alleles and environmental stressors in the development of post‐concussive symptoms after pediatric mild traumatic brain injury显示文摘 | Kim Smyth Sandeep S Sandhu Susan Crawford Deborah Dewey Jillian Parboosingh Karen M Barlow | 2014 | Dev Med Child Neurol2014，，1： | 2 |
| 6 | Insulin resistance is associated with increased cardiovascular risk in Asian Indians with normal glucose tolerance-the Chennai Urban Rural Epidemiology Study(CURES-66)显示文摘 | Sandeep S Gokulakrishnan K Deeps M | | 0，，： | 1 |
| 7 | Non-linear dynamic behaviors of rolling element bearings due to :surface waviness显示文摘 | S P Harsha K Sandeep R Prakash | 2004 | Journal of Sound and Vibration2004，272，35： | 1 |
| 8 | Serum visfatin in relation to visceral fat obesity,and type 2 diabetes mellitus in asian indians显示文摘 | Sandeep S Ve1murugan K Deepa R | 2007 | Metabolism2007，56，16： | 1 |
| 9 | Investigation of the PECVD TiO2-Si(100) interface显示文摘 | PATRICK R M LAURA J S SANDEEP K | 2004 | Applied Surface Science2004，233，： | 1 |
| 10 | Nonlinear dynamic behaviors of rolling element bearings due to surface waviness显示文摘 | Harsha S P Sandeep K Prakash R | 2004 | Journal of Sound and Vibration2004，272，3： | 1 |
| 11 | Preparation and Characterization of Bio-Nanocomposite Films Based on Soy Protein Isolate and Montmorillonite Using Melt Extrusion显示文摘 | KUMAR P SANDEEP K P ALAVI S | 2010 | Journal of Food Engineering2010，100，3： | 1 |
| 12 | A geometrically sound technique of vermilion repair in unilateral cleft lip显示文摘 | Rajesh S Powar Sandeep M | 2006 | Journal of Plastic Reconstructive & Aesthetic Surgery In Press2006，12，： | 1 |
| 13 | Nonlinear dynamic response of a rotor bearings due to surface waviness显示文摘 | Harsha S P Sandeep K Prakash R | 2004 | Nonlinear Dynamics2004，37，2： | 1 |
| 14 | Proline metabolism and its implications for plant-environment interaction显示文摘 | Paul E V Sandeep S | 2010 | The Arabidopsis Book2010，8，： | 1 |
| 15 | Electromagnetic analysis of radiometer calibration targets using dispersive 3D FDTD显示文摘 | Sandeep S Gasiewski A J | 2012 | IEEE Transactions on Antennas and Propagation2012，60，6： | 1 |
| 16 | Preparation,characterization,and water-sorption study of polyvinyl alcohol based hydrogels with grafted hydrophilic and hydrophobic segments显示文摘 | SANDEEP S BAJPAI A K KULLKARNI R A | 2005 | Appl Polym Sci2005，95，： | 1 |
| 17 | Foveal structure defined by spectral domain optical coherencetomography correlates with visual function after macular holesurgeiy显示文摘 | Kakarala V Ravi K Shailesh K Gupta B Vikram S Sandeep G | 2010 | Eur J Ophthalmol2010，20，3： | 1 |
| 18 | Nonlinear dynamic behaviors of rolling element bearings due to surface waviness显示文摘 | HARSHA S P SANDEEP K PRAKASH R | 2004 | Journal of Sound and Vibration2004，272，345： | 1 |
| 19 | Structure of the capsular polysaccharide of clostridium perfringers hobbs 5 as determined by NMR spectroscopy 显示文摘 | Sandeep S Glushka J Halbeek H | 1997 | Carbohydr Res1997，299，： | 1 |
| 20 | The effect of speed of balanced rotor on nonlinear vibrations associated with ball bearings 显示文摘 | Harsha S P Sandeep K Prakash R | 2003 | International Journal of Mechanical Sciences2003，45，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员