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| 1 | dentification of TRA2B-DNAH5 fusion as a novel oncogenic driver in human lung squamous cell carcinoma显示文摘 | Fei Li Zhaoyuan Fang Jian Zhang Chen Li Hongyan Liu Jufeng Xia Hongwen Zhu Chenchen auo Zhen Qin Fuming Li Xiangkun Han Yuetong Wang Yan Feng Ye Wang Wenjing Zhang Zuoyun Wang Yujuan Jin Yihua Sun Wenyi Wei Rong Zeng Haiquan Chen Hongbin Ji | 2016 | Cell Research2016，26，10： | 9 |
| 2 | Targeting a novel inducible GPX4 alternative isoform to alleviate ferroptosis and treat metabolic-associated fatty liver disease显示文摘Metabolic-associated fatty liver disease(MAFLD),which is previously known as non-alcoholic fatty liver disease(NAFLD),represents a major health concern worldwide with limited therapy.Here,we provide evidence that ferroptosis,a novel form of regulated cell death characterized by iron-driven lipid peroxidation,was comprehensively activated in liver tissues from MAFLD patients.The canonical-GPX4(cGPX4),which is the most important negative controller of ferroptosis,is downregulated at protein but not mRNA level.Interestingly,a non-canonical GPX4 transcript-variant is induced(inducible-GPX4,iGPX4)in MAFLD condition.The high fat-fructose/sucrose diet(HFFD)and methionine/choline-deficient diet(MCD)-induced MAFLD pathologies,including hepatocellular ballooning,steatohepatitis andfibrosis,were attenuated and aggravated,respectively,in cGPX4-and iGPX4-knockin mice.cGPX4 and iGPX4 isoforms also displayed opposing effects on oxidative stress and ferroptosis in hepatocytes.Knockdown of iGPX4 by siRNA alleviated lipid stress,ferroptosis and cell injury.Mechanistically,the triggered iGPX4 interacts with cGPX4 to facilitate the transformation of cGPX4 from enzymatic-active monomer to enzymatic-inactive oligomers upon lipid stress,and thus promotes ferroptosis.Co-immunoprecipitation and nano LC–MS/MS analyses confirmed the interaction between iGPX4 and cGPX4.Our results reveal a detrimental role of non-canonical GPX4 isoform in ferroptosis,and indicate selectively targeting iGPX4 may be a promising therapeutic strategy for MAFLD. | Jie Tong Dongjie Li Hongbo Meng Diyang Sun Xiuting Lan Min Ni Jiawei Ma Feiyan Zeng Sijia Sun Jiangtao Fu Guoqiang Li Qingxin Ji Guoyan Zhang Qirui Shen Yuanyuan Wang Jiahui Zhu Yi Zhao Xujie Wang Yi Liu Shenxi Ouyang Chunquan Sheng Fuming Shen Pei Wang | 2022 | Acta Pharmaceutica Sinica B2022，12，9： | 3 |
| 3 | Hand Vein Recognition Algorithm Based on NMF with Sparsity and Clustering Property Constraints in Feature Mapping Space显示文摘Most of the existed vein features are lack of robustness to light intensity variation,and some algorithms rely on the specified vein data sets,which leads to the limitation of real applications.To solve the problems,we propose a novel vein recognition algorithm based on Nonnegative matrix factorization(NMF)with double regularization terms.The innovations of our algorithm are mainly reflected in the following two aspects:in order to improve feature robustness,a novel feature mapping function is designed to map the initial Histogram of oriented gradient(HOG)feature to a new space;to enhance the recognition performance,an effective NMF model is presented,which not only reduces feature dimension,but also optimizes the feature sparsity and clustering property simultaneously.Experiments show that the proposed algorithm can achieve satisfactory results in terms of False rejection rate(FRR)and False acceptance rate(FAR),which indicates that our algorithm is valuable for other classification problems. | JIA Xu SUN Fuming LI Haojie CAO Yudong | 2019 | Chinese Journal of Electronics2019，28，6： | 2 |
| 4 | Detection and estimation of mixed paddy rice cropping patterns with MODIS data显示文摘 | Dailiang Peng Alfredo R. Huete Jingfeng Huang Fuming Wang Huasheng Sun | 2010 | International Journal of Applied Earth Observations and Geoinformation2010，，1： | 2 |
| 5 | Towards No-Reference Image Quality Assessment Based on Multi-Scale Convolutional Neural Network显示文摘Image quality assessment has become increasingly important in image quality monitoring and reliability assuring of image processing systems.Most of the existing no-reference image quality assessment methods mainly exploit the global information of image while ignoring vital local information.Actually,the introduced distortion depends on a slight difference in details between the distorted image and the non-distorted reference image.In light of this,we propose a no-reference image quality assessment method based on a multi-scale convolutional neural network,which integrates both global information and local information of an image.We first adopt the image pyramid method to generate four scale images required for network input and then provide two network models by respectively using two fusion strategies to evaluate image quality.In order to better adapt to the quality assessment of the entire image,we use two different loss functions in the training and validation phases.The superiority of the proposed method is verified by several different experiments on the LIVE datasets and TID2008 datasets. | Yao Ma Xibiao Cai Fuming Sun | 2020 | Computer Modeling in Engineering & Sciences2020，，4： | 2 |
| 6 | Design and comparison of minimal symmetric model-subset for maneuvering target tracking显示文摘Model-set is utilized in state estimation for maneuvering target tracking.Two minimal symmetric model-subsets are designed and investigated by moment matching method,which include hypersphere-symmetric model-subset and axis-symmetric model-subset,if system mode is a random variable and obeys certain probability distribution.They can be used as the fundamental model-subset for multiple models estimation with fixed structure,variable structure and moving bank.The model-groups constructed by above designed subsets are given,which give the practical guidance for use of model-set in multiple models approach with a variable structure.Simulation results show that the performances of two minimal model-set significantly outperform the corresponding model-sets with fixed spacing. | Fuming Sun Xu E Hongyu Ma | 2010 | Journal of Systems Engineering and Electronics2010，21，2： | 2 |
| 7 | A New Concentrated Emulsion Polymerization Pathway 显示文摘 | Ruckenstein E Fuming Sun | 1992 | J Appl Poym Sci1992，46，： | 1 |
| 8 | Detection and estimation of mixed paddy rice cropping patterns with MODIS data显示文摘 | Dailiang Peng Alfredo R. Huete Jingfeng Huang Fuming Wang Huasheng Sun | 2010 | International Journal of Applied Earth Observations and Geoinformation2010，，1： | 1 |
| 9 | Rechargeable Aqueous Zinc-Ion Batteries in MgSO4/ZnSO4 Hybrid Electrolytes显示文摘MgSO4 is chosen as an additive to address the capacity fading issue in the rechargeable zinc-ion battery system of MgxV2O5·nH2O//ZnSO4//zinc.Electrolytes with different concentration ratios of ZnSO4 and MgSO4 are investigated.The batteries measured in the 1 M ZnSO4^-1 M MgSO4 electrolyte outplay other competitors,which deliver a high specific capacity of 374 mAh g^-1 at a current density of 100 mA g^-1 and exhibit a competitive rate performance with the reversible capacity of 175 mAh g^-1 at 5 A g^-1.This study provides a promising route to improve the performance of vanadium-based cathodes for aqueous zinc-ion batteries with electrolyte optimization in cost-effective electrolytes. | Yingmeng Zhang Henan Li Shaozhuan Huang Shuang Fan Lingna Sun Bingbing Tian Fuming Chen Ye Wang Yumeng Shi Hui Ying Yang | 2020 | Nano-Micro Letters2020，12，5： | 1 |
| 10 | Karyotypes of nineteen species of Asteraceae in the Hengduan Mountains and adjacent regions显示文摘The Hengduan Mountains region is a biodiversity hotspot. In this study, we report the karyotypes of 19 species(21 populations) of Asteraceae from this region, 14 of which are reported for the first time. We also examined polyploidy in Asteraceae plants and summarized karyotype data in the literature for 69 congeneric taxa. In these genera, there were five different ploidy levels in the region, though the most dominant was diploid(73.08%). There is no direct evidence that ploidy level and karyotype asymmetry are associated with the distribution of recorded Asteraceae species from the Hengduan Mountains. This suggests that polyploidy(26.92%) may not play an important role in the evolutionary history of these plants, even though, among these genera, the ratio of paleopolyploidy was high(46.15%). | Wenguang Sun Xiangguang Ma Jianwen Zhang Fuming Su Yonghong Zhang Zhimin Li | 2017 | Plant Diversity2017，39，4： | 0 |
| 11 | EFFECT OF MAGNETIC FIELD ON MARTENSITIC TRANSFORMATION IN Fe-21Ni-4Mn ALLOY显示文摘The pulsed magnetic field induced martensitic transformation with isothermal and athermalkinetics in Fe-2Ni-4Mn(wt-%)alloy has been studied by means of magnetizationmeasurements,optical microscopy and thermodymical analyses.It is shown that there exits acritical magnetic intensity for induing martensitic transformation at a given temperatureabove Ms.The critical magnetic field increases linearly with increasing ΔT= T-M_S.Themagnetic field strongly promotes the athermal martensitic transforamtion and restrains theisothermal one.The entropy change ΔS for athermal transformation at Ms is 4.13 J/mol·K.The effect of magnetic field on martensitic transformation in Fe-21Ni-4Mn alloy is main-ly due to Zeeman effect.Lath,plate and butterfly martensities were observed under magneticfield. | SUN Enxi Dalian Railway College,Dalian,ChinaYANG Dazhi Dalian University of Technology,Dalian,ChinaXU Zuyao (T.Y.Hsu) Shanghai Jiaotong University,Shanghai,ChinaYANG Fuming ZHAO Ruwen Institute of Physics,Academia Sinica,Beijing,China YANG Dazhi,Professor,Dalian University of Technology,Dalian 116024,China | 1991 | Acta Metallurgica Sinica(English Letters)1991，4，1： | 0 |
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