|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Circular smooth muscle contributes to esophageal shortening during peristalsis显示文摘AIM:To study the angle between the circular smooth muscle(CSM) and longitudinal smooth muscle(LSM) fibers in the distal esophagus.METHODS:In order to identify possible mechanisms for greater shortening in the distal compared to proximal esophagus during peristalsis,the angles between the LSM and CSM layers were measured in 9 cadavers.The outer longitudinal layer of the muscularis propria was exposed after stripping the outer serosa.The inner circular layer of the muscularis propria was then revealed after dissection of the esophageal mucosa and the underlying muscularis mucosa.Photographs of each specimen were taken with half of the open esophagus folded back showing both the outer longitudinal and inner circular muscle layers.Angles were measured every one cm for 10 cm proximal to the squamocolumnar junction(SCJ) by two independent investigators.Two human esophagi were obtained from organ transplant donors and the angles between the circular and longitudinal smooth muscle layers were measured using micro-computed tomography(micro CT) and Image J software.RESULTS:All data are presented as mean ± SE.The CSM to LSM angle at the SCJ and 1 cm proximal to SCJ on the autopsy specimens was 69.3 ± 4.62 degrees vs 74.9 ± 3.09 degrees,P = 0.32.The CSM to LSM angle at SCJ were statistically significantly lower than at 2,3,4 and 5 cm proximal to the SCJ,69.3 ± 4.62 degrees vs 82.58 ± 1.34 degrees,84.04 ± 1.64 degrees,84.87 ± 1.04 degrees and 83.72 ± 1.42 degrees,P = 0.013,P = 0.008,P = 0.004,P = 0.009 respectively.The CSM to LSM angle at SCJ was also statistically significantly lower than the angles at 6,7 and 8 cm proximal to the SCJ,69.3 ± 4.62 degrees vs 80.18 ± 2.09 degrees,81.81 ± 1.75 degrees and 80.96 ± 2.04 degrees,P = 0.05,P = 0.02,P = 0.03 respectively.The CSM to LSM angle at 1 cm proximal to SCJ was statistically significantly lower than at 3,4 and 5 cm proximal to the SCJ,74.94 ± 3.09 degrees vs 84.04 ± 1.64 degrees,84.87 ± 1.04 degrees and 83.72 ± 1.42 degrees,P = 0.019,P = 0.008,P = 0.02 respectively.At 10 cm above SCJ the angle was 80.06 ± 2.13 degrees which is close to being perpendicular but less than 90 degrees.The CSM to LSM angles measured on virtual dissection of the esophagus and the stomach on micro CT at the SCJ and 1 cm proximal to the SCJ were 48.39 ± 0.72 degrees and 50.81 ± 1.59 degrees.Rather than the angle of the CSM and LSM being perpendicular in the esophagus we found an acute angulation between these two muscle groups throughout the lower 10 cm of the esophagus.CONCLUSION:The oblique angulation of the CSM may contribute to the significantly greater shortening of distal esophagus when compared to the mid and proximal esophagus during peristalsis. | Anil K Vegesna Keng-Yu Chuang Ramashesai Besetty Steven J Phillips Alan S Braverman Mary F Barbe Michael R Ruggieri Larry S Miller | 2012 | World Journal of Gastroenterology2012，18，32： | 7 |
| 2 | 美白牙膏去除牙外源性色斑的八周效果观察显示文摘目的 :评价含有 1%焦磷酸钠、7%三聚硫酸钠、0 .2 4 3 %氟化钠及 10 %高清洁二氧化硅的牙膏减少外源性牙色斑的效果。方法 :采用双盲、分层、二单位平行观察的临床研究方法。根据改良 L obene色斑指数 (L obene stain in-dex m ethod)均数、性别、吸烟习惯将 91名年龄为 18~ 5 5岁的研究对象平衡地分为两组 ,随机地分配使用试验或对照牙膏。于基线、第 4周及第 8周固定由一名检查者完成研究对象的色斑指数测定。结果 :86人完成了该研究。8周临床研究表明 ,使用美白牙膏的研究对象较对照组的牙齿色斑指数均数降低了 3 7.1% (P=0 .0 0 0 1)。结论 :与对照组牙膏相比 ,使用含有 1%焦磷酸钠、7%三聚硫酸钠、0 .2 4 3 %氟化钠及 10 %高清洁二氧化硅的牙膏可以有效地减少牙外源性色斑。 | 胡德渝 庞若愚 佘晓晴 雷德伦 Volpe A R DeVizio W Petrone M E Zhang Y P Chaknis P Miller S Miller J | 1999 | 华西口腔医学杂志1999，17，3： | 7 |
| 3 | Incidence of brain metastasis in patients with esophageal carcinoma显示文摘AIM:To determine the incidence of brain metastasis in a contemporary group of patients with carcinoma of the esophagus.METHODS:Retrospective analysis of 53 patients with esophageal carcinoma who received radiotherapy as a component of treatment between 1998 and 2007,including patient and tumor characteristics,and subsequent diagnosis of brain metastasis.The association between the histological type of esophageal cancer and the incidence of brain metastasis was assessed using Fisher's exact test.RESULTS:Forty-four of the fifty-three patients in this study had adenocarcinoma and nine had squamous cell carcinoma,ranging from stage ⅡA-ⅣB.Primary treatment was surgery with neoadjuvant chemoradiotherapy (trimodality therapy) in 19% of patients;chemoradiotherapy in 42%;and surgery and adjuvant radiotherapy in 7%.Twenty-five percent of patients inthis study received palliative radiotherapy.The overall incidence of brain metastasis in this cohort was 13%.Adenocarcinoma was the primary tumor histology in all of the patients who developed brain metastasis,representing an incidence of 16% in this subgroup.No patients with squamous cell carcinoma received trimodality therapy.The association between histology and brain metastasis was not statistically significant.CONCLUSION:The incidence of brain metastasis in this contemporary cohort of patients with esophageal carcinoma is higher than previously reported and was confined to those with adenocarcinoma. | Ron S Smith Robert C Miller | 2011 | World Journal of Gastroenterology2011，17，19： | 6 |
| 4 | Recent development in aluminium alloys for aerospace applications显示文摘 | A Heinz A Haszler C Keidel S Moldenhauer R Benedictus W.S Miller | 2000 | Materials Science & Engineering A2000，，1： | 5 |
| 5 | Phytochemical constituents and antibacterial efficacy of the flowers of Peltophomm pterocarpum(DC.) Baker ex Heyne显示文摘Objective:To investigate the preliminary phytochemistry and antibacterial activity of the flower extract of Peltophorum pterocarpum.Methods:Phytochemical analysis was done by using the standard methods given by Harbone.The methanolic flower extract were tested against Escherichia coli,Klebsiella pneumonia,Pseudomonas aeruginosa.Staphylococcus aureus. Bacillus cereus,Salmonella typhi,Serratia marsecens,Acinetobacter baumannii.Enterobacter sp., Proteus mirabilis.Enterococcus faecalis and Streptococcus pyogenes by the agar disc diffusion method.Results:Preliminary phytochemical screening of flower extract showed the presence of phenolic compounds,flavonoids.saponins,steroids,tannins,xanthoproteic,carboxylic acids, coumarins and carbohydrates.The flower extract of Peltophorum pteroearpum showed significant activity against four gram positive(Staphylococcus aureus.Bacillus cereus.Enlerococcus faecalis and Streptococcus pyogenes) and three gram negative bacteria(Proteus mirabilis,Acinetohacter baumannii and Serratia marsecens).out of 12 pathogenic bacteria studied.Conclusion:The findings of the present study confirm the presence of significant antibacterial activity against human pathogens in the flowers of Peltophorum pleracarpum. | Sukumaran S Kiruba S Mahesh M Nisha SR Miller Paul Z Ben CP Jeeva S | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，9： | 4 |
| 6 | Function of longitudinal vs circular muscle fibers in esophageal peristalsis, deduced with mathematical modeling显示文摘We summarize from previous works the functions of circular vs. longitudinal muscle in esophageal peristaltic bolus transport using a mix of experimental data, the conservation laws of mechanics and mathematical modeling. Whereas circular muscle tone generates radial closure pressure to create a local peristaltic closure wave, longitudinal muscle tone has two functions, one physiological with mechanical implications, and one purely mechanical. Each of these functions independently reduces the tension of individual circular muscle fibers to maintain closure as a consequence of shortening of longitudinal muscle locally coordinated with increasing circular muscle tone. The physiological function is deduced by combining basic laws of mechanics with concurrent measurements of intraluminal pressure from manometry, and changes in cross sectional muscle area from endoluminal ultrasound from which local longitudinal shortening (LLS) can be accurately obtained. The purely mechanical function of LLS was discovered from mathematical modeling of peristaltic esophageal transport with the axial wall motion generated by LLS. Physiologically, LLS concentrates circular muscle fibers where closure pressure is highest. However, the mechanical function of LLS is to reduce the level of pressure required to maintain closure. The combined physiological and mechanical consequences of LLS are to reduce circular muscle fiber tension and power by as much as 1/10 what would be requiredfor peristalsis without the longitudinal muscle layer, a tremendous benefit that may explain the existence of longitudinal muscle fiber in the gut. We also review what is understood of the role of longitudinal muscle in esophageal emptying, reflux and pathology. | James G Brasseur Mark A Nicosia Anupam Pal Larry S Miller | 2007 | World Journal of Gastroenterology2007，13，9： | 4 |
| 7 | 美白牙膏去除牙齿外源性色斑的临床效果观察显示文摘目的 与仅含有 0 .32 1%氟化钠的牙膏相比 ,评价含有 0 .32 1%氟化钠及 2 0 %高清洁二氧化硅 (HCS)的牙膏减少外源性牙色斑的效果。方法 采用双盲、分层、二单位平行观察的临床研究方法。根据Lobene色斑指数均数 (色斑指数包括染色部位及染色程度 )、性别、将 15 8名年龄为 18~ 6 5岁的研究对象平衡地分为两组 ,随机地分配使用试验或对照牙膏。于基线、第 4周及第 8周固定由一名检查者完成研究对象的色斑指数测定。结果 4周时 ,使用美白牙膏的研究对象较对照组的牙齿色斑面积减少 17.4% ,染色程度减少 19.2 % (P <0 .0 1)。 8周时 ,使用美白牙膏的研究对象较对照组的牙齿色斑面积减少 38.6 % ,染色程度减少 39.6 % (P <0 .0 1)。结论 与对照组牙膏相比 ,使用含有 0 .32 1%氟化钠及 2 0 | 李雪 胡德渝 YP Zhang S Miller J Miller ME Petrone W Devizio AR Volpe | 2001 | 广东牙病防治2001，9，3： | 3 |
| 8 | Ileocecal valve dysfunction in small intestinal bacterial overgrowth: A pilot study显示文摘AIM: To explore whether patients with a defective ileocecal valve (ICV)/cecal distension reflex have small intestinal bacterial overgrowth. METHODS: Using a colonoscope, under conscious sedation, the ICV was intubated and the colonoscope was placed within the terminal ileum (TI). A manometry catheter with 4 pressure channels, spaced 1 cm apart, was passed through the biopsy channel of the colonoscope into the TI. The colonoscope was slowly withdrawn from the TI while the manometry catheter was advanced. The catheter was placed across the ICV so that at least one pressure port was within the TI, ICV and the cecum respectively. Pressures were continuously measured during air insufflation into the cecum, under direct endoscopic visualization, in 19 volunteers. Air was insufflated to a maximum of 40 mmHg to prevent barotrauma. All subjects underwent lactulose breath testing one month after the colonoscopy. The results of the breath tests were compared with the results of the pressures within the ICV during air insufflation. RESULTS: Nineteen subjects underwent colonoscopy with measurements of the ICV pressures after intubation of the ICV with a colonoscope. Initial baseline readings showed no statistical difference in the pressures of the TI and ICV, between subjects with positive lactulose breath tests and normal lactulose breath tests. The average peak ICV pressure during air insufflation into the cecum in subjects with normal lactu-lose breath tests was significantly higher than cecal pressures during air insufflation (49.33 ± 7.99 mmHg vs 16.40 ± 2.14 mmHg, P = 0.0011). The average percentage difference of the area under the pressure curve of the ICV from the cecum during air insufflations in subjects with normal lactulose breath tests was significantly higher (280.72% ± 43.29% vs 100% ± 0%, P = 0.0006). The average peak ICV pressure during air insufflation into the cecum in subjects with positive lactulose breath tests was not significantly different than cecal pressures during air insufflation 21.23 ± 3.52 mmHg vs 16.10 ± 3.39 mmHg. The average percentage difference of the area under the pressure curve of the ICV from the cecum during air insufflation was not significantly different 101.08% ± 7.96% vs 100% ± 0%. The total symptom score for subjects with normal lactulose breath tests and subjects with positive lactu-lose breath tests was not statistically different (13.30 ± 4.09 vs 24.14 ± 6.58). The ICV peak pressures during air insufflations were significantly higher in subjects with normal lactulose breath tests than in subjects with positive lactulose breath tests (P = 0.005). The average percent difference of the area under the pressure curve in the ICV from cecum was significantly higher in subjects with normal lactulose breath tests than in subjects with positive lactulose breath tests (P = 0.0012). Individuals with positive lactulose breath tests demonstrated symptom scores which were significantly higher for the following symptoms: not able to finish normal sized meal, feeling excessively full after meals, loss of appetite and bloating. CONCLUSION: Compared to normal, subjects with a positive lactulose breath test have a defective ICV cecal distension reflex. These subjects also more commonly have higher symptom scores. | Larry S Miller Anil K Vegesna Aiswerya Madanam Sampath Shital Prabhu Sesha Krishna Kotapati Kian Makipour | 2012 | World Journal of Gastroenterology2012，18，46： | 3 |
| 9 | 基于自适应光学的视网膜单细胞光学相干层析成像技术显示文摘 | 屈军乐 Ravi S JONNAL Karen E THORN Donald T MILLER | 2004 | 生物物理学报2004，20，2： | 3 |
| 10 | Hepatocellular carcinoma locoregional therapies:Outcomes and future horizons显示文摘Hepatocellular carcinoma(HCC)is the most common primary cancer of the liver and has an overall five-year survival rate of less than twenty percent.For patients with unresectable disease,evolving liver-directed locoregional therapies provide efficacious treatment across the spectrum of disease stages and via a variety of catheter-directed and percutaneous techniques.Goals of locoregional therapies in HCC may include curative intent in early-stage disease,bridging or downstaging to surgical resection or transplantation for early or intermediate-stage disease,and local disease control and palliation in advanced-stage disease.This review explores the outcomes of chemoembolization,bland embolization,radioembolization,and percutaneous ablative therapies.Attention is also given to prognostic factors related to each of the respective techniques,as well as future directions of locoregional therapies for HCC. | Mina S Makary Stuart Ramsell Eric Miller Eliza W Beal Joshua D Dowell | 2021 | World Journal of Gastroenterology2021，27，43： | 2 |
| 11 | On bend-stretch forming of aluminum extruded tubes -Ⅰ:experiments 显示文摘 | MILLER J E KYRIAKIDES S BASTARD A H | 2001 | International J of Mechanical Sciences2001，，43： | 2 |
| 12 | Challenges for fuel cells in transport applications显示文摘 | Chalk S G Miller J F Wagner F W | 2000 | Journal of Power Sources2000，86，： | 2 |
| 13 | Improved relations decribing directional control in eletron genetic wave guidance显示文摘 | Marcatili E A J Miller S E | 1969 | Bellsyst Tech J1969，48，9： | 2 |
| 14 | The definition and rendering of terrain maps显示文摘 | Miller Gavin S P | 1986 | Computer Graphics1986，20，4： | 2 |
| 15 | 视网膜单细胞成像技术研究显示文摘建立了一台基于37单元变形镜、Shack-hartman波前像差传感器和12位科研级CCD相机的自适应光学视网膜相机。采用一个中心波长为679nm的超辐射二极管(SLD)作为相机的光源,通过将超辐射二极管和多模光纤耦合,显著减小了SLD光源的空间相干性,从而消除了散斑噪声对成像的影响。多模光纤的输出提供了一种高亮度、均匀照明的光源,使人眼视网膜单细胞成像的速度达到4.8幅 秒。 | 屈军乐 JONNAL R S THORN K E MILLER D T | 2004 | 激光生物学报2004，13，3： | 2 |
| 16 | Base stock level determination for high cost low demand critical repairable spares 显示文摘 | Dhakar T S Schmidt C P Miller D M | 1994 | Computers and Operations Research1994，21，： | 2 |
| 17 | Label-retaining liver cancer cells are relatively resistant to sorafenib显示文摘 | Hong-Wu Xin Chenwi M Ambe Danielle M Hari Gordon W Wiegand Tyler C Miller Jin-Qiu Chen Andrew J Anderson Satyajit Ray John E Mullinax Tomotake Koizumi Russell C Langan Douglas Burka Michelle A Herrmann Paul K Goldsmith Alexander Stojadinovic Udo Rudloff S | 2013 | Gut2013，，12： | 2 |
| 18 | Recent development in aluminium alloys for the automotive industry 显示文摘 | Miller W S Zhuang L Bottema J | 2000 | Materials Science and Engineering2000，280，1： | 2 |
| 19 | Improved relation describing directional control in electromagnetic wave guidance显示文摘 | MARCATILI E A J MILLER S E | 1969 | Bell Syst Tech J1969，48，： | 2 |
| 20 | Automatic-repeat-request error-control schemes显示文摘 | LIN S COSTELLO D J MILLER M J | 1984 | IEEE Commun Mag1984，22，： | 2 |
您所在的机构暂未开通此部分的功能，请联系管理员