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| 1 | In situ decomposition of metal-organic frameworks into ultrathin nanosheets for the oxygen evolution reaction显示文摘氧进化反应(OER ) 是一个枢轴的过程为切开水并且包含氧电极的许多另外的精力技术。此处,新合成策略被建议准备 OER 催化剂基于一简单在共同基于的醋酸盐氢氧化物的 situ 分解还灵活金属器官的框架(MOF ) 。这个过程与优秀部件可控制性允许各种各样的 2D 氢氧化物 ultrathin nanosheets (UNS ) 的直接制造。同样获得的共同基于的氢氧化物 UNS 由于众多的活跃地点的暴露为 OER 表明优异催化活动。特别地, CoNi 氢氧化物 UNS 展出低过电位() 在 10 和 100 妈的当前的密度的 324 和 372 mV ? 沬? | Kai He Zhen Cao Ruirui Liu Ya Miao Yi Ding | 2016 | Nano Research2016，9，6： | 7 |
| 2 | Energy-level dependent H_2_O_2 production on metal-free,carbon-content tunable carbon nitride photocatalysts显示文摘Light-driven production of H_2O_2 from water and molecular oxygen could be a promising way for obtaining both solar fuels and fundamental chemicals. During that process, the H_2O_2 yield is strongly dependent on the reaction pathway associated with two-electron reduction of dioxygen by the photo-generated electrons. Herein, we synthesized a series of metal-free, carbon-content tunable carbon nitride photocatalysts(named C_3N_4-Carbon) by a facile hydrothermal reaction and subsequent thermal treatment at appropriate temperatures. The energy levels of the C_3N_4-Carbon catalysts vary with the carbon doping level, which is conveniently tuned by changing the initial glucose concentration during the hydrothermal reaction. The surface carbon species evolve with the carbon content and the nitrogen atoms in the structure of carbon nitride are partially substituted by foreign carbon atoms based on XPS measurements. The optimal catalyst leads to the highest H_2O_2 yield of 1271 μmol L^(-1) in an acidic aqueous solution(pH 3) after a reaction period of 4 h, twice higher than the pristine C_3N_4. In addition, the largest formation rate constant and the smallest decomposition rate constant of H_2O_2 are obtained on the optimal one according to the kinetics analyses. The decomposition tests of H_2O_2 indicate that the formation rate could be a dominant factor impacting the H_2O_2 yield. The conduction band position of the optimal catalyst is positively shifted to 0.06 V versus RHE, which is more favorable to the reduction of dioxygen to H_2O_2(O2/H_2O_2 at 0.69 V versus RHE). The positive shift of valence band also improves hole collection and leads to enhanced formation of H_2O_2. | Ruirui Wang Xin Zhang Fan Li Ding Cao Min Pu Dandan Han Junjiao Yang Xu Xiang | 2018 | Journal of Energy Chemistry2018，27，2： | 4 |
| 3 | Effect of Gubi prescription on caveolin-1 expression and phosphoinositide 3 kinase/protein kinase B and Fas signal pathways in rats with knee osteoarthritis显示文摘OBJECTIVE: To investigate the effects of Gubi prescription on the expression of caveolin-1, and the phosphoinositide 3 kinase/protein kinase B(PI3 K/Akt) and Fas signal pathways in rats with knee osteoarthritis(KOA).METHODS: Forty KOA model rats were established using a modification of Hulth's method. Rats were divided into five groups by the random number method: model, positive drug(Vicolli group), and high-, medium-, and low-dose Gubi prescription groups(n = 8/group). In the sham surgery group(n = 8), only anterior and posterior cruciate ligaments of rats were exposed during surgery. A normal group(n = 8) consisted of rats with no treatment. Rats were intragastrically administered corresponding drugs once every day for eight consecutive weeks. Then, rat synovial membranes were extracted and histomorphological changes were recorded. m RNA expression was measured by q-PCR.Serum superoxide dismutase(SOD), malondialdehyde(MDA), nitric oxide(NO), and interleukin 1β(IL-1β) levels were measured. Western blotting determined the effects of Gubi prescription on protein expressions of caveolin-1, Bax, Bcl-2, Fas, and caspase-3 in chondrocytes from KOA rats. The knee cartilage of rats was excised and cultured under aseptic conditions. After coincubation of chondrocytes with Gubi prescription-containing serum, IL-1β, and si RNA, Western blotting was used to determine the protein expressions of caveolin-1, Bax, Bcl-2, Fas, and caspase-3.RESULTS: The morphological score of the articular synovium in the model group was significantly higher than in the normal group(P < 0.01). The morphological score in the high-and mediumdose Gubi prescription groups was lower than in the model group(P < 0.05). Chondrocytes from the decoction-containing serum group had a lower expression of Bax(P < 0.05), and higher expressions of Bcl-2(P < 0.05) and caspase-3(P < 0.05) compared with the model group. Chondrocytes in the decoction-containing serum group had higher expressions of Bax and Bcl-2(P < 0.01) and lower expressions of caveolin-1 and Fas(P < 0.05) compared with the model group. Compared with the model group, Bax and caspase-3 expressions were reduced in the chondrocytes of all three Gubi prescription groups(P < 0.05) whereas Bcl-2 expression was increased(P < 0.05). Compared with the model group, the expressions of caveolin-1 and Fas(P < 0.05) were reduced in groups that received high-and medium-doses of Gubi prescription. Gubi prescription increased the serum level of SOD and significantly reduced those of MDA, NO and IL-1β(P < 0.05).CONCLUSION: Gubi prescription suppressed the chondrocyte-related PI3 K/Akt and Fas signal pathways and inhibited the overexpression of caveolin-1 in rat chondrocytes. | He Xiaojin Wang Lei Zhou Xueping Xu Luzhou Cao Jing Wang Ruirui Wang Min Xie Guoqian | 2020 | Journal of Traditional Chinese Medicine2020，40，2： | 3 |
| 4 | Import of Rift Valley fever to China:a potential new threat?显示文摘Several recent studies in Virologica Sinica and other journals have highlighted the enormous international challenge of emerging arboviral diseases,such as Zika virus disease,dengue,and chikungunya(Islam et al.,2015;Maurice et al.,2015;Dai et al.,2016;Deng et al.,2016;Song et al.,2016;Wang et al.,2016;Xu et al.,2016;Zhang et al.,2016;Zhou | Xinliang FU Lifang Wang Bo Fang Ruirui Ma Yun Zheng San Huang Pei Zhou Zongxi Cao Jin Tian Shoujun Li Guihong Zhang | 2016 | Virologica Sinica2016，31，5： | 2 |
| 5 | The C_(6)D_(6)detector system on the Back-n beam line of CSNS显示文摘Introduction The neutron capture cross sections are very important in the field of nuclear device design and basic physics research.Hydrogen-free liquid scintillator such as C_(6)D_(6)detectors are widely used in the neutron capture cross-sectional measurements for the low neutron sensitivity and fast time response.The Back-n white neutron source at China Spallation Neutron Source is the first spallation white neutron source in China,and it is suitable for neutron capture cross-sectional measurement.Materials and methods A C_(6)D_(6)detector system was built in the Back-n experimental station.The pulse height weighting technique was used to determine the system’s detection efficiency.The response to gamma rays of the C_(6)D_(6)detector was measured,and the energy resolution function was determined.Monte Carlo simulation with Geant4 code was carried out to get the weighting function of this C_(6)D_(6)detector system.Additionally,the systematic uncertainty of the weighting function was also determined.Conclusion According to the experimental and simulation results,this C_(6)D_(6)detector system can be used to measure neutron capture cross section. | Jie Ren Xichao Ruan Jie Bao Guangyuan Luan Wei Jiang Qi An Huaiyong Bai Ping Cao Qiping Chen Yonghao Chen Pinjing Cheng Zengqi Cui Ruirui Fan Changqing Feng Minhao Gu Fengqin Guo Changcai Han Zijie Han Guozhu He Yongcheng He Yuefeng He Hanxiong Huang Weiling Huang Xiru Huang Xiaolu Ji Xuyang Ji Haoyu Jiang Hantao Jing Ling Kang Mingtao Kang Bo Li Lun Li Qiang Li Xiao Li Yang Li Yang Li Rong Liu Shubin Liu Xingyan Liu Yinglin Ma Changjun Ning Binbin Qi Zhaohui Song Hong Sun Xiaoyang Sun Zhijia Sun Zhixin Tan Hongqing Tang Jingyu Tang Pengcheng Wang Qi Wang Taofeng Wang Yanfeng Wang Zhaohui Wang Zheng Wang Jie Wen Zhongwei Wen Qingbiao Wu Xiaoguang Wu Xuan Wu Likun Xie Yiwei Yang Han Yi Li Yu Tao Yu Yongji Yu Guohui Zhang Jing Zhang Linhao Zhang Liying Zhang Qingmin Zhang Qiwei Zhang Xianpeng Zhang Yuliang Zhang Zhiyong Zhang Yingtan Zhao Liang Zhou Zuying Zhou Danyang Zhu Kejun Zhu Peng Zhu | 2019 | Radiation Detection Technology and Methods2019，3，3： | 1 |
| 6 | Effects of stochastic food deprivation on energy budget,body mass and activity in Swiss mice显示文摘When small animals are faced with an unpredictable food supply,they can adapt by altering different components of their energy budget such as energy intake,metabolic rate,rate of non-shivering thermogenesis(NST)or behaviour.The present study examined the effect of stochastic food deprivation(FD)on body mass,food intake,resting metabolic rate(RMR),NST and behaviour in male Swiss mice.During a period of 4 weeks' FD,animals were fed ad libitum for a randomly assigned 4 days each week,but were deprived of food for the other 3 days.The results showed that body mass significantly dropped on FD days compared to controls.Food intake of FD mice increased significantly on ad libitum days,ensuring cumulative food intake,final body mass,fat mass,RMR and NST did not differ significantly from controls.Moreover,gastrointestinal tract mass increased in FD mice,but digestibility decreased.In general,activity was higher on deprived days,and feeding behaviour was higher on ad libitum days suggesting that Swiss mice are able to compensate for stochastic FD primarily by increasing food intake on ad libitum days,and not by reducing energy expenditure related to RMR or NST. | Zhijun ZHAO Jing CAO Ye TIAN Ruirui WANG Guiying WANG | 2009 | Current Zoology2009，55，4： | 1 |
| 7 | Pharmacological inhibition of BAP1 recruits HERC2 to competitively dissociate BRCA1-BARD1, suppresses DNA repair and sensitizes CRC to radiotherapy显示文摘Radiotherapy is widely used in the management of advanced colorectal cancer(CRC).However,the clinical efficacy is limited by the safe irradiated dose.Sensitizing tumor cells to radiotherapy via interrupting DNA repair is a promising approach to conquering the limitation.The BRCA1-BARD1 complex has been demonstrated to play a critical role in homologous recombination(HR)DSB repair,and its functions may be affected by HERC2 or BAP1.Accumulated evidence illustrates that the ubiquitination-deubiquitination balance is involved in these processes;however,the precise mechanism for the cross-talk among these proteins in HR repair following radiation hasn’t been defined.Through activity-based profiling,we identified PT33 as an active entity for HR repair suppression.Subsequently,we revealed that BAP1 serves as a novel molecular target of PT33 via a CRISPR-based deubiquitinase screen.Mechanistically,pharmacological covalent inhibition of BAP1 with PT33 recruits HERC2 to compete with BARD1 for BRCA1 interaction,interrupting HR repair.Consequently,PT33 treatment can substantially enhance the sensitivity of CRC cells to radiotherapy in vitro and in vivo.Overall,these findings provide a mechanistic basis for PT33-induced HR suppression and may guide an effective strategy to improve therapeutic gain. | Xin Yue Tingyu Liu Xuecen Wang Weijian Wu Gesi Wen Yang Yi Jiaxin Wu Ziyang Wang Weixiang Zhan Ruirui Wu Yuan Meng Zhirui Cao Liyuan Le Wenyan Qiu Xiaoyue Zhang Zhenyu Li Yong Chen Guohui Wan Xianzhang Bu Zhenwei Peng Ran-yi Liu | 2023 | Acta Pharmaceutica Sinica B2023，13，8： | 1 |
| 8 | Effect of caffeic acid derivatives on polychlorinated biphenyls induced hepatotoxicity in male mice显示文摘Chronic exposure to coplanar polychlorinated biphenyls(PCBs),a potent inducer of toxic reactive oxygen species(ROS),in the environment and food can cause liver diseases.It remains unknown whether caffeic acid derivatives(CADs) exerted protective effect on PCB-induced hepatotoxicity.We sought to evaluate the activities of 3CADs on PCB169-induced oxidative stress and DNA damage in the liver.Male ICR mice were administered with1 μmol/mL PCB169 at 5 mL/kg body weight for 2 weeks.The mice were given CADs by gastric gavage for 3weeks.We found that PCB169 decreased the growth rate and reduced the levels of superoxide dismutase(SOD),glutathione(GSH) and GSH peroxidase(GPx).It increased the liver weight,malondialdehyde(MDA)and 8-hydroxy-2'-deoxyguanosine(8-OHdG) levels and CYPlAl activity in the liver tissues and plasma of mice(P<0.05).Pretreatment of mice with CADs restored the above parameters to normal levels.There was a synergistic protective effect between CADs in preventing MDA and 8-OHdG formation and inducing CYPlAl and phase II metabolism enzyme(SOD,GPx) activities(P<0.05).In conclusion,PCB169 induced hepatotoxicity and pretreatment with CADs had synergistic protective effects on liver damage. | Ruirui Li Shuyuan Cao Jinfeng Dai Li Wang Lei Li Yubang Wang Wenqin Yin Yuting Ye | 2014 | The Journal of Biomedical Research2014，28，5： | 1 |
| 9 | Dynamic recrystallization-induced temperature insensitivity of yield stress in single-crystal Al1.2CrFeCoNi micropillars显示文摘High-entropy alloys, a new class of metallic materials, exhibit excellent mechanical properties at high temperatures. In spite of the worldwide interest, the underlying mechanisms for temperature dependence of mechanical properties of these alloys remain poorly understood. Here, we systemically investigate the mechanical behaviors and properties of Al_(1.2)CrFeCoNi(comprising a body-centered cubic phase) and Al_(0.3)CrFeCoNi(comprising a face-centered cubic phase) single-crystal micropillars with three orientations([100], [110], and [111]) at temperatures varying from 300 to 675 K by using in situ compression of micropillars inside a scanning electron microscope. The results show that the yield stresses of Al_(1.2)CrFeCoNi micropillars are insensitive to temperature changes, and their flow stresses and work hardening rates increase slightly with increasing temperature from 300 to550 K, which differs from the typical temperature dependence of yield/flow stresses in metals and alloys. In contrast,Al_(0.3)CrFeCoNi micropillars exhibit typical thermal softening. Furthermore, it is found that the Al_(1.2)CrFeCoNi micropillars exhibit a transition from homogenous deformation to localized deformation at a critical temperature, while the Al_(0.3)CrFeCoNi micropillars always maintain a well-distributed and fine slip deformation. Detailed transmission electron microscopy analyses reveal that dynamic recrystallization(involving dislocation tangles, and formation of dislocation cell structures and sub-grains)plays a key role in the observed temperature insensitivity of the yield stress and increasing flow stress(and work hardening rate)with increasing temperature in the Al_(1.2)CrFeCoNi micropillars, and that thermally activated dislocation slip leads to thermal softening of the Al_(0.3)CrFeCoNi micropillars. The differences in deformation modes and temperature dependence of the mechanical properties between Al_(1.2)CrFeCoNi and Al_(0.3)CrFeCoNi essentially originate from the differences in dislocation activities and slip systems since the two alloys adopt different phases. Our findings provide key insights in the temperature dependence of mechanical properties and deformation behaviors of high-entropy alloys with body-centered cubic and face-centered cubic phases. | HUANG RuiRui ZHANG Qian ZHANG Xuan LI JianGuo CAO TangQing YAO JiaHao XUE YunFei GAO HuaJian LI XiaoYan | 2021 | Science China(Technological Sciences)2021，64，1： | 1 |
| 10 | Detector development at the Back-n white neutron source显示文摘Purpose Back-n is a white neutron beamline at China spallation neutron source,which was established in the year of 2018.It is a powerful facility for nuclear data measurement,neutron detector calibration,and radiation effect research.Method A series of detectors were built for different experiments,including beam monitoring,beam profile measurement,neutron induced secondaries(fission fragments,light charged particles and gamma)cross section measurement,and neutron resonance radiography,etc.A common digitization electronics and a cluster-based DAQ were developed for these detector systems.Most detectors have been employed at Back-n and serviced for experiments from the beginning of the beamline running.Results and conclusion As an overview of detectors of Back-n,the details of the detector design and the experiment performing are described in this paper.Some developing systems,e.g.,MTPC and B-MCP,are also included. | Fan Ruirui Li Qiang Bao Jie Li Yang Liu Rong Jiang Wei Ren Jie Zhang Qiwei Cao Ping Gu Minhao Ren Zhizhou Yi Han Tang Jingyu An Qi Bai Haofan Bai Jiangbo Chen Qiping Chen Yonghao Chen Zhen Cui Zengqi Fan Anchuan Feng Changqing Feng Fanzhen Gao Keqing Han Changcai Han Zijie He Guozhu He Yongcheng Hong Yang Hu Yiwei Huang Hanxiong Jia Weihua Jiang Haoyu Jiang Zhijie Jin Zhengyao Kang Ling Li Bo Li Chao Li Gong Li Jiawen Li Xiao Liu Jie Liu Shubin Luan Guangyuan Ning Changjun Qi Binbin Ruan Xichao Song Zhaohui Sun Kang Tan Zhixin Tang Shengda Wang Pengcheng Wang Zhaohui Wen Zhongwei Wu Xiaoguang Wu Xuan Xie Likun Yang Yiwei Yu Yongji Zhang Guohui Zhang Linhao Zhang Mohan Zhang Xianpeng Zhang Yuliang Zhang Yue Zhang Zhiyong Zhao Maoyuan Zhou Luping Zhou Zhihao Zhu Kejun The CSNS Back-n Collaboration | 2023 | Radiation Detection Technology and Methods2023，7，2： | 0 |
| 11 | Ultrathin nanoporous metal-semiconductor heterojunction photoanodes for visible light hydrogen evolution显示文摘Plasmonic 金属半导体 nano 异质接面(NHJ ) 与他们的优异 photocatalytic 表演,为太阳能的有效利用提供机会。然而,科学意义和技术挑战为新产生留在合适的金属半导体 NHJ photoelectrodes 的发展灵活 optoelectronic 设备,它经常要求复杂处理。此处,我们报导综合三维(3D ) NHJ photoelectrodes 由保角地,涂层镉硫化物(CdS ) nanolayers 经由一个灵巧的电极淀积方法拍摄到 ultrathin nanoporous 黄金(NPG ) 上。NPG 的局部性的表面电浆子回声(LSPR ) 提高电子洞对产生和分离。而且,直接接触接口和 NHJ 的高传导性的框架结构增加 photogenerated 搬运人分离和运输。因此, NHJ 展览显然相对在任何一个黄金(Au ) 上扔的 CdS 提高了光电流密度和氢进化率在在可见光的照耀下面的 0 V 对 SCE (浸透的甘汞电极) 的陪衬或做氟的符号的锡氧化物(FTO ) 。而且,他们表明令人惊讶地稳定的 photoelectrochemical 氢进化(PEC -- 他) 在连续照耀的 104 s 上的活动。 | Weiqing Zhang Yunfeng Zhao Kai He Jun Luo Guoliang Li Ruirui Liu Siyu Liu Zhen Cao Pengtao Jing Yi Ding | 2018 | Nano Research2018，11，4： | 0 |
| 12 | Research on the relationship between strategic leadership of senior managers of state-owned enterprises and business performance显示文摘 | Ruirui Cao Jun Lu | 2014 | International Journal of Technology Management2014，，3： | 0 |
| 13 | The functional analysis of state-owned enterprise human resource management in supporting culture construction显示文摘 | Ruirui Cao Jun Lu | 2014 | International Journal of Technology Management2014，，2： | 0 |
| 14 | Synthesis and Characterization of Natural Polymer/Inorganic Antibacterial Nanocomposites显示文摘In order to increase antibacterial abilities and avoid the aggregation of nanoparticle,AgZnO nanocomposites were studied in the network structure which contains bonds,and these bonds are formed by hydrolysis reaction between Ti(TBOU) 4(TBOT) and the water that in Persimmon tannin solution.The size and morphology of Ag-ZnO nanocomposites were investigated by scanning electron microscopy(SEM) and field emission scanning electron microscopy(FE-SEM).The antibacterial properties of nanocomposites were examined by minimal bactericidal concentration(MBC).Results showed that this kind of antibacterial nanocomposites composites(ANPs) have excellent antibacterial abilities and without aggregation. | 王勇 程顺林 WANG Fuzhong GAO Ming CAO Ruirui | 2013 | Journal of Wuhan University of Technology(Materials Science)2013，28，5： | 0 |
| 15 | Dual-ratiometric magnetic resonance tunable nanoprobe with acidic-microenvironment-responsive property to enhance the visualization of early tumor pathological changes显示文摘The development of microenvironment-responsive nanoprobes has shown great promise for use in magnetic resonance imaging(MRI),with the advantage of significantly improved specificity and good biocompatibility.However,the clinical application of responsive probes is hampered by a lack of biological sensitivity for early molecular diagnostics and visualizing microenvionment of metabolism reprogramming in tumor progression.Here,we report on a dual-ratiometric magnetic resonance tunable(DMRT)nanoprobe designed by crosslinking different ratios of transferrin chelating gadolinium and superparamagnetic nanoparticles,complexed to a pH responsive biocompatible polymer.This dually activatable nanoprobe enables pH-dependent tumor microenvironment visualization,providing exceptional quantitative pathophysiological information in vitro and in vivo.When used in combination with dual-contrast enhancement triple subtraction imaging technique(DETSI),this smart nanoprobe guarantees the diagnosis of early-stage diseases.We envisage that this novel integrated nanoplatform will provide a new paradigm for the clinical translation of robust DMRT nanoprobes for early disease detection and staging,as well as microenvironment visualization and disease progression monitoring. | Rong Cao Ning Tang Yi Zhu An Chen Yumeng Li Renbin Ge Yuan Li Zhongyi Huang Jiajing Guo Jiali Deng Hongwei Lu Ziwei Lu Helen Forgham Thomas PDavis Ruirui Qiao Zhongling Wang | 2023 | Nano Research2023，16，7： | 0 |
| 16 | Nitrogen addition reduced carbon mineralization of aggregates in forest soils but enhanced in paddy soils in South China显示文摘Background:Despite the crucial role of nitrogen(N)availability in carbon(C)cycling in terrestrial ecosystems,soil organic C(SOC)mineralization in different sizes of soil aggregates under various land use types and their responses to N addition is not well understood.To investigate the responses of soil C mineralization in different sized aggregates and land use types to N addition,an incubation experiment was conducted with three aggregate-size classes(2000,250,and 53μm)and two land use types(a Chinese fir plantation and a paddy land).Results:Cumulative C mineralization of the<53-μm fractions was the highest and that of microaggregates was the lowest in both forest and paddy soils,indicating that soil aggregates enhanced soil C stability and reduced the loss of soil C.Cumulative C mineralization in all sizes of aggregates treated with N addition decreased in forest soils,but that in microaggregates and the<53-μm fraction increased in paddy soils treated with 100μgNg−1.Moreover,the effect sizes of N addition on C mineralization of forest soils were below zero,but those of paddy soils were above zero.These data indicated that N addition decreased SOC mineralization of forest soils but increased that of paddy soils.Conclusions:Soil aggregates play an important role in soil C sequestration,and decrease soil C loss through the increase of soil C stability,regardless of land use types.N addition has different effects on soil C mineralization in different land use types.These results highlight the importance of soil aggregates and land use types in the effects of N deposition on the global terrestrial ecosystem C cycle. | Ruirui Cao Longchi Chen Xincun Hou Xiaotao Lü Haimei Li | 2021 | Ecological Processes2021，10，1： | 0 |
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