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| 1 | An elastic-plastic contact model for line contact structures显示文摘Although numerical simulation tools are now very powerful,the development of analytical models is very important for the prediction of the mechanical behaviour of line contact structures for deeply understanding contact problems and engineering applications.For the line contact structures widely used in the engineering field,few analytical models are available for predicting the mechanical behaviour when the structures deform plastically,as the classic Hertz’s theory would be invalid.Thus,the present study proposed an elastic-plastic model for line contact structures based on the understanding of the yield mechanism.A mathematical expression describing the global relationship between load history and contact width evolution of line contact structures was obtained.The proposed model was verified through an actual line contact test and a corresponding numerical simulation.The results confirmed that this model can be used to accurately predict the elastic-plastic mechanical behaviour of a line contact structure. | Haibin Zhu Yingtao Zhao Zhifeng He Ruinan Zhang Shaopeng Ma | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，5： | 8 |
| 2 | Copper as a single metal atom based photo-,electro-,and photoelectrochemical catalyst decorated on carbon nitride surface for efficient CO_(2) reduction:A review显示文摘The processes of photocatalytic CO_(2) reduction(pCO_(2)R)and electrochemical CO_(2) reduction(ECO_(2)R)have attracted considerable interest owing to their high potential to address many environmental and energy-related issues.In this aspect,a single Cu atom decorated on a carbon nitride(CN)surface(Cu-CN)has gained increasing popularity because of its unique advantages,such as excellent atom utilization and ultrahigh catalytic activity.CN-particularly graphitic CN(g-C_(3)N_(4))-is a photo-and electrocatalyst and used as an important support material for single Cu atom-based catalysts.These key functions of Cu-CN-based catalysts can improve the catalytic performance and stability in the pCO_(2)R and ECO_(2)R during the application process.In this review,we focus on Cu as a single metal atom decorated on CN for efficient photoelectrochemical CO_(2) reduction(pECO_(2)R),where ECO_(2)R increases the electrocatalytic active area and promotes electron transfer,while pCO_(2)R enhances the surface redox reaction by efficiently using photogenerated charges and offering integral activity as well as an active interface between Cu and CN.Interactions of single Cu atom-based photo-,electro-,and photoelectrochemical catalysts with g-C_(3)N_(4) are discussed.Moreover,for a deeper understanding of the history of the development of pCO_(2)R and ECO_(2)R,the basics of CO_(2) reduction,including pCO_(2)R and ECO_(2)R over g-C_(3)N_(4),as well as the structural composition,characterization,unique design,and mechanism of a single atom site are reviewed in detail.Finally,some future prospects and key challenges are discussed. | Lulu Li Israr Masood ul Hasan Farwa Ruinan He Luwei Peng Nengneng Xu Nabeel Khan Niazi Jia-Nan Zhang Jinli Qiao | 2022 | Nano Research Energy2022，1，2： | 7 |
| 3 | Electrochemically-driven interphase conditioning of magnesium electrode for magnesium sulfur batteries显示文摘The earth-abundant magnesium metal is a kind of promising anode material due to its low reduction potential (-2.356V vs. SHE), high volumetric and gravimetric specific capacities of 3882 mAh cm-3 and 2234 mAh g_1 respectively [1]. Moreover, the magnesium anode shows high safety due to the non-dentritic electrodeposition mechanism during cycling, which is related to the strong Mg-Mg bonding and the consequent high energy barrier between the crystal boundaries of different crystal orientation [2]. | Yaqi Li Pengjian Zuo Ruinan Li Mengxue He Yulin Ma Yingxin Shi Xinqun Cheng Chunyu Du Geping Yin | 2019 | Journal of Energy Chemistry2019，28，10： | 1 |
| 4 | Upregulation of RIN3 induces endosomal dysfunction in Alzheimer’s disease显示文摘Background In Alzheimer’s Disease(AD),about one-third of the risk genes identified by GWAS encode proteins that function predominantly in the endocytic pathways.Among them,the Ras and Rab Interactor 3(RIN3)is a guanine nucleotide exchange factor(GEF)for the Rab5 small GTPase family and has been implicated to be a risk factor for both late onset AD(LOAD)and sporadic early onset AD(sEOAD).However,how RIN3 is linked to AD pathogenesis is currently undefined.Methods Quantitative PCR and immunoblotting were used to measure the RIN3 expression level in mouse brain tissues and cultured basal forebrain cholinergic neuron(BFCNs).Immunostaining was used to define subcellular localization of RIN3 and to visualize endosomal changes in cultured primary BFCNs and PC12 cells.Recombinant flag-tagged RIN3 protein was purified from HEK293T cells and was used to define RIN3-interactomes by mass spectrometry.RIN3-interacting partners were validated by co-immunoprecipitation,immunofluorescence and yeast two hybrid assays.Live imaging of primary neurons was used to examine axonal transport of amyloid precursor protein(APP)andβ-secretase 1(BACE1).Immunoblotting was used to detect protein expression,processing of APP and phosphorylated forms of Tau.Results We have shown that RIN3 mRNA level was significantly increased in the hippocampus and cortex of APP/PS1 mouse brain.Basal forebrain cholinergic neurons(BFCNs)cultured from E18 APP/PS1 mouse embryos also showed increased RIN3 expression accompanied by early endosome enlargement.In addition,via its proline rich domain,RIN3 recruited BIN1(bridging integrator 1)and CD2AP(CD2 associated protein),two other AD risk factors,to early endosomes.Interestingly,overexpression of RIN3 or CD2AP promoted APP cleavage to increase its carboxyl terminal fragments(CTFs)in PC12 cells.Upregulation of RIN3 or the neuronal isoform of BIN1 increased phosphorylated Tau level.Therefore,upregulation of RIN3 expression promoted accumulation of APP CTFs and increased phosphorylated Tau.These effects by RIN3 was rescued by the expression of a dominant negative Rab5(Rab5S34N)construct.Our study has thus pointed to that RIN3 acts through Rab5 to impact endosomal trafficking and signaling.Conclusion RIN3 is significantly upregulated and correlated with endosomal dysfunction in APP/PS1 mouse.Through interacting with BIN1 and CD2AP,increased RIN3 expression alters axonal trafficking and procession of APP.Together with our previous studies,our current work has thus provided important insights into the role of RIN3 in regulating endosomal signaling and trafficking. | Ruinan Shen Xiaobei Zhao Lu He Yongbo Ding Wei Xu Suzhen Lin Savannah Fang Wanlin Yang Kijung Sung Brian Spencer Robert A.Rissman Ming Lei Jianqing Ding Chengbiao Wu | 2020 | Translational Neurodegeneration2020，9，2： | 1 |
| 5 | The mechanisms of grain growth of Mg alloys:A review显示文摘Grain growth directly influences the plasticity and strength of Mg alloys.As the grain size decreases from the microscale to the nanoscale,the plasticity of Mg alloys continually increases,whereas the strength first increases and later decreases.These trends are observed because the plastic deformation mechanism changes from dislocation–twinning dominance to grain boundary dominance.In this study,the factors influencing grain growth,such as the temperature of plastic deformation/annealing,second-phase particles and solute atoms,are examined to aid effective control of the grain size.Additionally,the mechanisms of grain growth,typically induced by strain and thermal activation,are clarified.Strain-induced grain boundary migration is attributable to the difference in the strain energy stored in adjacent grains with high-density dislocations.Heat-induced grain boundary migration is driven by the difference in the energy of the grain boundary/subgrain boundary and boundary curvature.Abnormal grain growth can be induced by anisotropy of the strain energy,anisotropy of the grain boundary mobility,depinning of the second phase and high misorientation gradient. | Qinghua Chen Ruinan Chen Jian Su Qingsong He Bin Tan Chao Xu Xu Huang Qingwei Dai Jian Lu | 2022 | Journal of Magnesium and Alloys2022，10，9： | 1 |
| 6 | Solid-state bonding process induced highly synergistic mechanical properties of 6061 Al alloy joint by shear deformation显示文摘Obtaining a highly synergistic mechanical property between joint and base metal(BM)in aluminum(Al)alloy is a chronic problem.In this work,shear bonding technology is applied to a commercial 6061 Al alloy.The results show that a flat and uniform joint interface is obtained.The joint presents a highly synergistic mechanical property compared with BM,whether after shear bonding or heat treatment.The joint coefficient reaches 95.6%after shear bonding and exceeds 100%after heat treatment,which is better than the traditional connection method of aluminum alloy.The high joint coefficient mainly originates from the well-linked joint and gradient grain structure.The gradient grain structure is beneficial to activate more slip systems to coordinate plastic deformation.Although the fine-grained structure is sacrificed after heat treatment,higher strength and joint coefficient are obtained due to the higher work hardening.This newly developed method has a large potential for application to the infinite rolling of Al alloy sheets and can also be used for Al alloy connection in automobile,aerospace,rail transportation,and other fields.The findings in this work can provide essential theoretical support and application reference for the shear connection of Al alloy. | Peng Peng Jian Su Qingsong He Ruinan Chen Sensen Chai Daliang Yu Qingwei Dai Jian Lu | 2023 | Journal of Materials Science & Technology2023，，33： | 0 |
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