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| 1 | Regulation of epithelium-specific Ets-like factors ESE-1 and ESE-3 in airway epithelial cells: potential roles in airway inflammation显示文摘航线发炎是许多呼吸障碍的特点,例如气喘和膀胱的纤维变性。在发炎触发的航线基因表示的变化在这些疾病的致病起一个关键作用。基因连接研究建议 ESE-2 和 ESE-3,编码上皮特定的 Ets-domain-containing 抄写因素,是候选人气喘危险性基因。我们这里报导 et 家庭抄写因素 ESE-1 的另一个成员的表示,以及 ESE-3,起来在支气管的上皮的房间线由煽动性的 cytokines interleukin-1beta (IL-1beta ) 和肿瘤坏死 factor-alpha (TNF-alpha ) 调整了。有 IL-1beta 和 TNF-alpha 的这些房间的处理为 ESE-1 和 ESE-3 导致了信使 rna 表示的戏剧的增加。我们证明导致的表示被抄写因素 NF-kappaB 的激活调停。我们描绘了 ESE-1 和 ESE-3 倡导者并且识别了为导致 cytokine 的表达式被要求的 NF-kappaB 有约束力的序列。另外,我们也表明那 ESE-1 在上面调整 ESE-3 表示, down 由 cytokines 调整它的自己的正式就职。最后,我们在 Elf3 显示出那(对人的 ESE-1 相应) 猛烈老鼠,煽动性的 cytokine interleukin-6 (IL-6 ) 的表示是调整的 down。我们的调查结果建议 ESE-1 和 ESE-3 在航线发炎起一个重要作用。 | Jing Wu Rongqi Duan Huibi Cao Deborah Field Catherine M Newnham David R Koehler Noe Zamel Melanie A Pritchard Paul Hertzog Martin Post A Keith Tanswell Jim Hu | 2008 | Cell Research2008，18，6： | 6 |
| 2 | Effect of Traditional Chinese Medicine plus narrow-band medium-wave ultraviolet B radiation on moderate-to-severe psoriasis vulgaris in a case series显示文摘OBJECTIVE: To investigate the efficacy and safety of Traditional Chinese Medicine (TCM) therapy combined with ultraviolet B light therapy in the treatment of moderate-to-severe psoriasis. METHODS: Patients with moderate-to-severe psoriasis (skin lesion area > 10% of the body surface area) for 2 consecutive years were treated with TCM (oral and external use of herbal medicines, acupuncture, and herbal bathing) and narrow-band medium-wave ultraviolet B light treatment for 12 weeks. The treatment effect was evaluated based on the Psoriasis Area Severity Index (PASI), the achievement of a 50% reduction in the PASI (PASI50), the achievement of a 75% reduction in the PASI (PASI75), pruritus score, Dermatology Life Quality Index, and safety. RESULTS: A total of 95 outpatients were enrolled, and 92 subjects (96.8%) completed the 12-week treatment course. At baseline, the average proportion of the body surface area covered by skin lesions was 12.4%, and the average PASI was 17.7. All patients had previously been treated with conventional medicine (89.1% of patients received ultraviolet light treatment, 50.0% received glucocorticoids, and 21.7% received acitretin). After the 12-week treatment course, 22 patients (23.9%) achieved PASI75, and 43 (46.7%) achieved PASI50. The post-treatment pruritus score and Dermatology Life Quality Index of all treated patients were significantly lower than the respective baseline values (P < 0.0001). No adverse effects were detected by the monitoring of blood, urine, stools, liver and kidney function, and echocardiography.CONCLUSION: Comprehensive therapy comprising TCM therapy combined with ultraviolet B light therapy achieved good outcomes for patients with moderate-to-severe psoriasis. | Li Tiantian Zhou Dongmei Xu Xuying Qu Jianhua Jiang Chunyan Lan Haibing Lou Weihai Chen Weiwen Jin Li Liu Rongqi Liu Zhiyong Zhang Cang Duan Lanhua Bohua Li Xu Jingna Zhou Tao Jiang Xi Cao Wei Zhang Guangzhong Liu Jianping Sun Liyun Wang Ping | 2019 | Journal of Traditional Chinese Medicine2019，39，5： | 2 |
| 3 | Adsorption and desorption behaviour of taurine on macroporous adsorption resins 显示文摘 | Tang Zhigang Zhou Rongqi Duan Zhangting | 2001 | Jourmal of Chemical Technology and Biotechnology2001，76，3： | 1 |
| 4 | Separation tff gibberellic acid ( GA3 ) by macroporous adsorption resins 显示文摘 | Zhigang Tang Rongqi Zhou Zhanting Duan | 2000 | Journal of Chemical Technology and Biotechnology2000，75，8： | 1 |
| 5 | Adsorption and desorption behaviour of taurine on macroporous adsorption resins显示文摘 | Tang Zhigang Zhou Rongqi Duan Zhanfing | 2001 | Journal of Chemical Technology and Biotechnology2001，76，7： | 1 |
| 6 | Separation of gibberellic acid (GA3) by macroporous adsorption resins显示文摘 | TANG Zhigang ZHOU Rongqi DUAN Zhanting | 2000 | Journal of Chemical Technology and Biotechnology2000，75，8： | 1 |
| 7 | Adsorption and desorption behaviour of taurine on macroporous adsorption resins显示文摘 | TANG Zhigang ZHOU Rongqi DUAN Zhanting | 2001 | Journal of Chemical Technology and Biotechnology2001，76，7： | 1 |
| 8 | Adsorption and desorption behaviour of taurine on macroporous adsorption resins显示文摘 | Tang Zhigang Zhou Rongqi Duan Zhanting | 2001 | Journal of Chemical Technology and Biotechnology2001，76，： | 1 |
| 9 | Separation of isopropanol from aqueous solution by salting-out extraction显示文摘 | TANG Zhigang ZHOU Rongqi DUAN Zhanting | 2001 | Journal of Chemical Technology and Biotechnology2001，76，： | 1 |
| 10 | Application of scaled particle theory in extractive distillation with salt显示文摘 | LEI Zhigang ZHOU Rongqi DUAN Zhanting | 2002 | Fluid Phase Equilibria2002，200，1： | 1 |
| 11 | Adsorption and desorption behaviour of taurine on macroporous adsorption resins显示文摘 | Tang Zhigang Zhou Rongqi Duan Zhanting | 2001 | Journal of Chemical Technology and Biotechnology2001，76，： | 1 |
| 12 | Separa-tion of isopropanol from aqueous solution by salting-out ex-traction 显示文摘 | Tang Zhigang Zhou Rongqi Duan Zhanting | 2001 | Journal of Chemical Technology and Bioteehnolo- gy2001，76，3： | 1 |
| 13 | Adsorption and desorption behaviour of taurine on macroporous adsorption resins显示文摘 | Tang Zhigang Zhou Rongqi Duan Zhanting | 2001 | Journal of Chemical Technology and Biotechnology2001，76，： | 1 |
| 14 | Highly efficient retinal gene delivery with helper-dependent adenoviral vectors显示文摘There have been significant advancements in the field of retinal gene therapy in the past several years.In particular,therapeutic efficacy has been achieved in three separate human clinical trials conducted to assess the ability of adeno-associated viruses(AAV)to treat of a type of Leber’s congenital amaurosis caused by RPE65 mutations.However,despite the success of retinal gene therapy with AAV,challenges remain for delivering large therapeutic genes or genes requiring long DNA regulatory elements for controlling their expression.For example,Stargardt’s disease,a form of juvenile macular degeneration,is caused by defects in ABCA4,a gene that is too large to be packaged in AAV.Therefore,we investigated the ability of helper dependent adenovirus(HD-Ad)to deliver genes to the retina as it has a much larger transgene capacity.Using an EGFP reporter,our results showed that HD-Ad can transduce the entire retinal epithelium of a mouse using a dose of only 1105 infectious units and maintain transgene expression for at least 4 months.The results demonstrate that HD-Ad has the potential to be an effective vector for the gene therapy of the retina. | Simon Lam Huibi Cao Jing Wu Rongqi Duan Jim Hu | 2014 | Genes & Diseases2014，1，2： | 1 |
| 15 | Adsorption and desorptionbehaviour of taurine on macroporous adsorption resins显示文摘 | Tang Zhigang Zhou Rongqi Duan zhanting | 2001 | J of Chem Tech and Bio2001，76，： | 1 |
| 16 | Adsorption and desorption behaviour of taurine on macroporous adsorption resins显示文摘 | Tang Zhigang Zhou Rongqi Duan zhanting | 2001 | J of Chem Tech and Bio2001，76，： | 1 |
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