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| 1 | Heart and lung, a dangerous liaison-Tako-tsubo cardiomyopathy and respiratory diseases: A systematic review显示文摘AIM: To investigate the possible association between Tako-tsubo cardiomyopathy(TTC)-a reversible clini-cal condition mimicking an acute myocardial infarction characterized by multifactorial pathophysiologic mecha-nisms- and respiratory system diseases. METHODS: We systematically searched PubMed and EMBASE medical information sources, to identify the different triggering causes, limiting our search to ar-ticles in English. The search keywords were: 'tako-tsubo cardiomyopathy', 'takotsubo', 'takotsubo cardiomyopa-thy', 'broken heart syndrome', 'stress-induced cardio-myopathy', 'apical ballooning syndrome', and 'ampulla cardiomyopathy in combination with respiratory dis-eases, lung, pulmonary disease. For each kind of dis-ease, we registered: author, year and country of study, patient sex, age, concurring situation, and outcome. RESULTS: Out of a total of 1725 articles found, we se-lected 37 papers reporting a total of 38 patients. As ex-pected, most patients were women(81.6%), mean age was 65 ± 10 years. Outcome was favorable in 100% of cases, and all the patients have been discharged un-eventfully in a few days. CONCLUSION: An association between respiratory diseases and TTC is likely to exist. Patients with severe respiratory diseases, due to the high dosages of β2-agonists used or to the need of invasive procedures, are highly exposed to the risk of developing TTC. | Roberto Manfredini Fabio Fabbian Alfredo De Giorgi Marco Pala Alessandra Mallozzi Menegatti Claudia Parisi Elisa Misurati Ruana Tiseo Massimo Gallerani Raffaella Salmi Eduardo Bossone | 2014 | World Journal of Cardiology2014，6，5： | 3 |
| 2 | Pulmonary embolism and internal jugular vein thrombosis as evocative clues of Lemierre's syndrome:A case report and review of the literature显示文摘Lemierre’s syndrome(LS)is an uncommon condition with oropharyngeal infections,internal jugular vein thrombosis,and systemic metastatic septic embolization as the main features.Fusobacterium species,a group of strictly anaerobic Gram negative rod shaped bacteria,are advocated to be the main pathogen involved.We report a case of LS complicated by pulmonary embolism and pulmonary septic emboli that mimicked a neoplastic lung condition.A Medline search revealed 173 case reports of LS associated with internal jugular vein thrombosis that documented the type of microorganism.Data confirmed high prevalence in young males with Gram negative infections(83.2%).Pulmonary embolism was reported in 8.7% of cases mainly described in subjects with Gram positive infections(OR=9.786;95%CI:2.577-37.168,P=0.001),independently of age and gender.Only four fatal cases were reported.LS is an uncommon condition that could be complicated by pulmonary embolism,especially in subjects with Gram positive infections. | Alfredo De Giorgi Fabio Fabbian Christian Molino Elisa Misurati Ruana Tiseo Claudia Parisi Benedetta Boari Roberto Manfredini | 2017 | World Journal of Clinical Cases2017，5，3： | 2 |
| 3 | 2013 Ambulatory Blood Pressure Monitoring Recommendations for the Diagnosis of Adult Hypertension, Assessment of Cardiovascular and other Hypertension-associated Risk, and Attainment of Therapeutic Goals显示文摘 | Ramón C. Hermida Michael H. Smolensky Diana E. Ayala Francesco Portaluppi Juan J. Crespo Fabio Fabbian Erhard Haus Roberto Manfredini Artemio Mojón Ana Moyá Luis Pi?eiro María T. Ríos Alfonso Otero Horia Balan José R. Fernández | 2013 | Chronobiology International2013，，3： | 1 |
| 4 | Purinergic stimulation of human mesenchymal stem cells potentiates their chemotactic response to CXCL12 and increases the homing capacity and production of proinflammatory cytokines显示文摘 | Davide Ferrari Sara Gulinelli Valentina Salvestrini Giovanna Lucchetti Roberta Zini Rossella Manfredini Luisa Caione Wanda Piacibello Marilena Ciciarello Lara Rossi Marco Idzko Sergio Ferrari Francesco Di Virgilio Roberto M. Lemoli | 2011 | Experimental Hematology2011，，3： | 1 |
| 5 | Breaking Heart显示文摘 | Roberto Manfredini Raffaella Salmi Fabio Fabbian Fabio Manfredini Massimo Gallerani Eduardo Bossone | 2013 | Heart Failure Clinics2013，，： | 1 |
| 6 | Takotsubo Cardiomyopathy: Overview显示文摘 | Eduardo Bossone Gianluigi Savarese Francesco Ferrara Rodolfo Citro Susanna Mosca Francesca Musella Giuseppe Limongelli Roberto Manfredini Antonio Cittadini Pasquale Perrone Filardi | 2012 | Heart Failure Clinics2012，，： | 1 |
| 7 | Monday preference in onset of takotsubo cardiomyopathy显示文摘 | Roberto Manfredini Rodolfo Citro Mario Previtali Olga Vriz Quirino Ciampi Marco Pascotto Ercole Tagliamonte Gennaro Provenza Fabio Manfredini Eduardo Bossone | 2010 | American Journal of Emergency Medicine2010，，6： | 1 |
| 8 | Chronobiological Patterns of Onset of Tako-Tsubo Cardiomyopathy显示文摘 | Rodolfo Citro Mario Previtali Daniella Bovelli Olga Vriz Costantino Astarita Marco Mariano Patella Gennaro Provenza Corinna Armentano Quirino Ciampi Giovanni Gregorio Massimo Piepoli Eduardo Bossone Roberto Manfredini | 2009 | Journal of the American College of Cardiology2009，，2： | 1 |
| 9 | Hypertension,abnormal blood pressure circadian pattern,and frailty:data from the literature显示文摘According to the National Health and Nutrition Examination Survey(NHANES)data,more than 65%of people aged≥60 years are hypertensive.[1]Diabetes mellitus,dyslipidemia,obesity and renal failure are frequently associated with hypertension,increasing the risk of negative outcomes,such as stroke and myocardial infarction. | Fabio Fabbian Alfredo De Giorgi Rosaria Cappadona Dario Gozzi Mauro Pasin Roberto De Giorgio Roberto Manfredini | 2018 | Journal of Geriatric Cardiology2018，15，12： | 1 |
| 10 | Seasonal and weekly patterns of hospital admissions for nonfatal and fatal myocardial infarction显示文摘 | Roberto Manfredini Fabio Manfredini Benedetta Boari Elisabetta Bergami Elisa Mari Susanna Gamberini Raffaella Salmi Massimo Gallerani | 2009 | American Journal of Emergency Medicine2009，，9： | 1 |
| 11 | Ambulatory diastolic blood pressure:a marker of comorbidity in elderly fit hypertensive individuals?显示文摘BACKGROUND Masked diastolic hypotension is a new blood pressure(BP)pattern detected by ambulatory blood pressure monitoring(ABPM)in elderly hypertensives.The aim of this study was to relate ABPM and comorbidity in a cohort of fit elderly subjects attending an outpatient hypertension clinic.METHODS Comorbidity was assessed by Charlson comorbidity index(CCI)and CHA_(2)DS_(2)VASc score.All subjects evaluated with ABPM were aged≥65 years.CCI and CHA_(2)DS_(2)VASc score were calculated.Diastolic hypotension was defined as mean am-bulatory diastolic BP<65 mmHg and logistic regression analysis was carried out in order to detect and independent relationship between comorbidity burden and night-time diastolic BP<65 mmHg.RESULTS We studied 174 hypertensive elderly patients aged 72.1±5.2 years,men were 93(53.4%).Mean CCI was 0.91±1.14 and mean CHA_(2)DS_(2)VASc score of 2.68±1.22.Subjects with night-time mean diastolic values<65 mmHg were higher in females[54.7%vs.45.3%,P=0.048;odds ratio(OR)=1.914,95%CI:1.047−3.500].Logistic regression analysis showed that only CHA_(2)DS_(2)-VASc score was independently associated with night-time mean diastolic values<65 mmHg(OR=1.518,95%CI:1.161−1.985;P=0.002),but CCI was not.CONCLUSIONS ABPM and comorbidity evaluation appear associated in elderly fit subjects with masked hypotension.Com-orbid women appear to have higher risk for low ambulatory BP. | Alfredo De Giorgi Rosaria Cappadona Caterina Savriè Benedetta Boari Ruana Tiseo Giulia Marta Viglione Christian Molino Elisa Misurati Mauro Pasin Roberto Manfredini Fabio Fabbian | 2022 | Journal of Geriatric Cardiology2022，19，4： | 0 |
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