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| 1 | Pancreaticoduodenectomy: Secondary stenting of the celiac trunk after inefficient median arcuate ligament release and reoperation as an alternative to simultaneous hepatic artery reconstruction显示文摘In patients undergoing pancreaticoduodenectomy(PD),unrecognized hemodynamically significant celiac axis(CA) stenosis impairs hepatic arterial flow by suppressing the collateral pathways supplying arterial flow from the superior mesenteric artery and leads to serious hepatobiliary complications due to liver and biliary ischemia, with a high rate of mortality. CA stenosis is usually due to an extrinsic compression by a previously asymptomatic median arcuate ligament(MAL). MAL is diagnosed by computerized tomography in about 10% of the candidates for PD, but only half are found to be hemodynamically significant during the gastroduodenal artery clamping test with Doppler assessment, which is mandatory before any resection. MAL release is usually efficient to restore an adequate liver blood inflow and prevent ischemic complications. In cases of failure in MAL release, postponed PD with secondary stenting of the CA and reoperation for PD should be considered as an alternative to immediate hepatic artery re-construction, which involves the risk of postoperative thrombosis of the arterial reconstruction. We recently used this two-stage strategy in a patient undergoing surgery for pancreatic adenocarcinoma. | Théophile Guilbaud Jacques Ewald Olivier Turrini Jean Robert Delpero | 2017 | World Journal of Gastroenterology2017，23，5： | 3 |
| 2 | Hepatitis C virus genotypes distribution and transmission risk factors in Luxembourg from 1991 to 2006显示文摘AIM:To analyze the Hepatitis C virus (HCV) genotype distribution and transmission risk factors in a population of unselected patients in Luxembourg. METHODS:Epidemiological information (gender, age and transmission risks) were collected from 802 patients newly diagnosed for hepatitis C and living in Luxembourg, among whom 228 patients referred from prison. Genotyping using 5'noncoding (5'NC) sequencing was performed. We compared categorical data using the Fisher's exact F-test and odds ratios (OR) were calculated for evaluating association of HCV genotype and risk factors. RESULTS:The sex ratio was predominantly male (2.2) and individuals aged less than 40 years represented 49.6% of the population. Genotype 1 was predominant (53.4%) followed by genotype 3 (33%). Among risk factors, intravenous drug usage (IVDU) was the most frequently reported (71.4%) followed by medical-related transmission (17.6%) including haemophilia, transfusion recipients and other nosocomial reasons. Genotype 3 was significantly associated to IVDU (OR = 4.84, P < 0.0001) whereas genotype 1 was significantly associated with a medical procedure (OR = 2.42, P < 0.001). The HCV genotype distribution from inmate patients differed significantly from the rest of the population (Chi-square test with four degrees of freedom, P < 0.0001) with a higher frequency of genotype 3 (46.5% vs 27.5%) and a lower frequency of genotype 1 and 4 (44.7% vs 56.8% and 5.3% vs 9.6%, respectively). IVDU was nearly exclusively reported as a risk factor in prison. CONCLUSION:We report the first description of the HCV genotype distribution in Luxembourg. The repartition is similar to other European countries, with one of the highest European prevalence rates of genotype 3 (33%). Since serology screening became available in 1991, IVDU remains the most common way of HCV transmission in Luxembourg. | Francois Roman Karin Hawotte Daniel Struck Anne-Marie Ternes Jean-Yves Servais Vic Arendt Patrick Hoffman Robert Hemmer Thérèse Staub Carole Seguin-Devaux Jean-Claude Schmit | 2008 | World Journal of Gastroenterology2008，14，8： | 3 |
| 3 | Quantitative gadopentetate-enhanced MR1 of breast tumors: testing of different analytic methods 显示文摘 | Helbich TH Roberts TP Gossmann A | 2000 | Magnetic Resonance Med2000，44，6： | 1 |
| 4 | A preliminary study of the effects of correction of anemia with recombinant human erythropoietin therapy on sleep, sleep disorders, and daytime sleep illness in hemodialysis patients(the SLEEPO Study)显示文摘 | Robert LB Mark RP Edward TH | 1999 | Am J Kidney Dis1999，34，6： | 1 |
| 5 | A Lymphotoxin-Driven Pathway to Hepatocellular Carcinoma显示文摘 | Johannes Haybaeck Nicolas Zeller Monika Julia Wolf Achim Weber Ulrich Wagner Michael Odo Kurrer Juliane Bremer Giandomenica Iezzi Rolf Graf Pierre-Alain Clavien Robert Thimme Hubert Blum Sergei A. Nedospasov Kurt Zatloukal Muhammad Ramzan Sandra Ciesek Th | 2009 | Cancer Cell2009，，4： | 1 |
| 6 | Malignancies after renal transplantation during 33 years at a single center显示文摘 | Gyula Végs? Maria Tóth Márta Hídvégi éva Toronyi Robert Mlanger Elek Dinya András Tóth Ferenc Perner Jen? Járay | 2007 | Pathology & Oncology Research2007，，1： | 1 |
| 7 | Wavelength modulation spectroscopy:combined frequency and intensity laser modulation显示文摘 | SCHILT S THVENAZ L ROBERT P | 2003 | Applied Optics2003，42，33： | 1 |
| 8 | The interrelationship of sputum inflammatory markem in patients with chronic bronchitis显示文摘 | Adan TH Bayley D Robert A | 1999 | Am J Respir Crit Care Med1999，160，： | 1 |
| 9 | Induction and chemotherapeutic response of two transplantable ductal adenocarcinomas of the pancreas in C57BL/6 mice显示文摘 | Corbett TH Roberts BJ Leopold WR | 1984 | Cancer Res1984，44，： | 1 |
| 10 | Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays,with a note on carcinogen structure显示文摘 | Corbett TH Griswold DP Jr Roberts BJ | 1975 | Cancer Res1975，35，： | 1 |
| 11 | Influence of TDZ and BA on adventitious shoot regeneration from apple leaves 显示文摘 | Chritel TH Robert TH | 1990 | Acta Horiculturae1990，280，： | 1 |
| 12 | Excess returns to R&D-intensive firms显示文摘 | CHAMBERS DENNIS ROSS JENNINGS ROBERT TH(DMP- SON | 2002 | Review of Accounting Studies2002，7，23： | 1 |
| 13 | Influnece of TDZ and BA on adventitious shoot regeneration from apple leaves显示文摘 | Chritel TH Robert TH | 1990 | Acta Hort1990，280，： | 1 |
| 14 | Vitamin I)2 formation from post-harvest UV-B treatment of mushrooms(Agaricus bisporus ) and rentention during storage显示文摘 | Roberts JS Teichert A MeHugh TH | 2008 | J Agric Food Chem2008，56，： | 1 |
| 15 | Platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes: a meta-analysis of all major randomised clinical trials显示文摘 | Eric Boersma Robert A Harrington David J Moliterno Harvey White Pierre Théroux Frans Van de Werf Anneke de Torbal Paul W Armstrong Lars C Wallentin Robert G Wilcox John Simes Robert M Califf Eric J Topol Maarten L Simoons | 2002 | The Lancet2002，，9302： | 1 |
| 16 | Brillouin gain spectrum characterisation in single-mode optical fibres显示文摘 | NIKLS M THVENAZ L ROBERT P | 1997 | Journal of Lightwave Technology1997，15，10： | 1 |
| 17 | Influence of TDZ and BA on adventitious shoot regeneration from apple leaves显示文摘 | Chritel TH Robert TH | 1990 | Acta Hort1990，280，： | 1 |
| 18 | Mucinous and Signet-Ring Cell Colorectal Cancers Differ from Classical Adenocarcinomas in Tumor Biology and Prognosis显示文摘 | Ulrich Nitsche Anina Zimmermann Christoph Sp?th Tara Müller Matthias Maak Tibor Schuster Julia Slotta-Huspenina Samuel A. K?ser Christoph W. Michalski Klaus-Peter Janssen Helmut Friess Robert Rosenberg Franz G. Bader | 2013 | Annals of Surgery2013，，5： | 1 |
| 19 | Evaluation of single agent and combinaation of chemotherapeutic agents in mouse clon carcinoma 显示文摘 | Cobrtt TH Grisword DP Jr Robert BJ | 1977 | Cancer1977，40，5： | 1 |
| 20 | A mouse colon - tumor model for experimental therapy显示文摘 | Corbett TH Griswold DP Jr Roberts B J Peckham J Schnabel FM Jr | 1975 | Cancer Chemother Rep1975，5，： | 1 |
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