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| 1 | What is the quantitative risk of gastric cancer in the first-degree relatives of patients? A meta-analysis显示文摘AIM To quantify the risk of gastric cancer in first-degree relatives of patients with the cancer. METHODS A comprehensive literature search was performed. Case-control trials comparing the frequency of a positive family history of gastric cancer in patients with gastric cancer, vs non-gastric cancer controls were retrieved. Studies with missed or non-extractable data, studies in children, abstracts, and duplicate publications were excluded. A meta-analysis of pooled odd ratios was performed using Review Manager 5.0.25. We performed subgroup analysis on Asian studies and a sensitivity analysis based on the quality of the studies, type of the outcome, sample size, and whether studies considered only first-degree relatives. RESULTS Thirty-two relevant studies out of 612 potential abstracts(n = 80690 individuals) were included. 19.0% of the patients and 10.9% of the controls had at least one relative with gastric cancer(P < 0.00001). The pooled relative risk for the development of gastric cancer in association with a positive family history was 2.35(95%CI: 1.96-2.81). The Cochran Q test for heterogeneity was positive(P < 0.00001, I 2 = 92%). After excluding the three outlier studies with the highest relative risks, heterogeneity remained significant(P < 0.00001, I 2 = 90%). The result was not different among Asian studies as compared to others and remained robust in several sensitivity analyses. In the 26 studies which exclusively analysed the history of gastric cancer in first-degree relatives, the relative risk was 2.71(95%CI: 2.08-3.53; P < 0.00001). CONCLUSION Individuals with a first-degree relative affected with gastric cancer have a risk of about 2.5-fold for the development of gastric cancer. This could be due to genetic or environmental factors. Screening and preventive strategies should be developed for this highrisk population. | Mohammad Yaghoobi Julia McNabb-Baltar Raheleh Bijarchi Richard H Hunt | 2017 | World Journal of Gastroenterology2017，23，13： | 13 |
| 2 | Nano-Fe_3O_4 encapsulated-silica particles bearing sulfonic acid groups as a magnetically separable catalyst for green and efficient synthesis of functionalized pyrimido[4,5-b]quinolines and indeno fused pyrido[2,3-d]pyrimidines in water显示文摘磁性的 nanoparticles 支持了硅石硫磺的酸为 pyrimido 的合成被用作有效催化剂[4,5-b ] 喹啉和 indeno 熔化了 pyrido [2,3-d ] 水里的嘧啶。需要的产品在优秀收益被获得。Fe3O4@SiO2SO3H 乐意地用一个外部磁铁被恢复并且没有反应的重要损失,能若干次被再使用。 | Firouzeh Nemati Raheleh Saeedirad | 2013 | Chinese Chemical Letters2013，24，5： | 6 |
| 3 | 磺酸基修饰的纳米Fe_3O_4包覆二氧化硅颗粒作为可磁分离催化剂高效催化芳香醛与1,3-环二酮的Knoevenagel缩合反应和Michael加成反应(英文)显示文摘Sulfonic acid-functionalized silica-coated nano-Fe3O4 particles(Fe3O4@SiO2-SO3H) have been prepared as a novel heterogeneous acid using a facile process.The material was subsequently identified as an efficient catalyst for the synthesis of a variety of tetraketone derivatives via the Knoevenagel condensation and Michael addition reactions of aromatic aldehydes to dimedone,1,3-indanedione,and 1,3-dimethyl barbituric acid.The catalyst could be readily recovered using a simple external magnet and reused several times without any significant loss in activity.The current catalytic process is both sustainable and economical because it operates under aqueous conditions,the catalyst can be recovered and reused,and the reactions themselves require only a short time and provide the products in high yield. | Firouzeh NEMATI Majid M.HERAVI Raheleh SAEEDI RAD | 2012 | 催化学报2012，33，11： | 4 |
| 4 | Pathophysiology of autism spectrum disorders:Revisiting gastrointestinal involvement and immune imbalance显示文摘Autism spectrum disorders(ASD)comprise a group of neurodevelopmental abnormalities that begin in early childhood and are characterized by impairment of social communication and behavioral problems including restricted interests and repetitive behaviors.Several genes have been implicated in the pathogenesis of ASD,most of them are involved in neuronal synaptogenesis.A number of environmental factors and associated conditions such as gastrointestinal(GI)abnormalities and immune imbalance have been linked to the pathophysiology of ASD.According to the March 2012 report released by United States Centers for Disease Control and Prevention,the prevalence of ASD has sharply increased during the recent years and one out of 88 children suffers now from ASD symptoms.Although there is a strong genetic base for the disease,several associated factors could have a direct link to the pathogenesis of ASD or act as modifiers of the genes thus aggravating the initial problem.Many children suffering from ASD have GI problems such as abdominal pain,chronic diarrhea,constipation,vomiting,gastroesophageal reflux,and intestinal infections.A number of studies focusing on the intestinal mucosa,its permeability,abnormal gut development,leaky gut,and other GI problem raised many questions but studies were somehow inconclusive and an expert panel of American Academy of Pediatrics has strongly recommended further investigation in these areas.GI tract has a direct connection with the immune system and an imbalanced immune response is usually seen in ASD children.Maternal infection or autoimmune diseases have been suspected.Activation of the immune system during early development may have deleterious effect on various organs including the nervous system.In this review we revisited briefly the GI and immune system abnormalities and neuropeptide imbalance and their role in the pathophysiology of ASD and discussed some future research directions. | Mohtashem Samsam Raheleh Ahangari Saleh A Naser | 2014 | World Journal of Gastroenterology2014，20，29： | 3 |
| 5 | Synthesis of Pyrazolo[3,4-d]pyrimidin-4-ones Catalyzed by Brensted-acidic Ionic Liquids as Highly Efficient and Reusable Catalysts显示文摘 | Tavakoli-Hoseini, Niloofar Moloudi, Raheleh Davoodnia, Abolghasem Shaker, Mohammad | 2011 | Chinese Journal of Chemistry2011，29，11： | 2 |
| 6 | Influence of MBBR carrier geometrical properties and biofilm thickness restraint on biofilm properties,effluent particle size distribution,settling velocity distribution,and settling behaviour显示文摘The relatively poor settling characteristics of particles produced in moving bed biofilm reactor(MBBR)outline the importance of developing a fundamental understanding of the characterization and settleability of MBBR-produced solids.The influence of carrier geometric properties and different levels of biofilm thickness on biofilm characteristics,solids production,particle size distribution(PSD),and particle settling velocity distribution(PSVD)is evaluated in this study.The analytical Vi CAs method is applied to the MBBR effluent to assess the distribution of particle settling velocities.This method is combined with microscopy imaging to relate particle size distribution to settling velocity.Three conventionally loaded MBBR systems are studied at a similar loading rate of 6.0 g/(m^(2)·day)and with different carrier types.The AnoxK^(TM)K5 carrier,a commonly used carrier,is compared to so-called thickness-restraint carriers,AnoxK^(TM)Z-carriers that are newly designed carriers to limit the biofilm thickness.Moreover,two levels of biofilm thickness,200μm and 400μm,are studied using AnoxK^(TM)Z-200 and Z-400 carriers.Statistical analysis confirms that K5 carriers demonstrated a significantly different biofilm mass,thickness,and density,in addition to distinct trends in PSD and PSVD in comparison with Z-carriers.However,in comparison of thickness-restraint carriers,Z-200 carrier results did not vary significantly compared to the Z-400 carrier.The K5 carriers showed the lowest production of suspended solids(0.7±0.3 gTSS/day),thickest biofilm(281.1±8.7μm)and lowest biofilm density(65.0±1.5 kg/m^(3)).The K5 effluent solids also showed enhanced settling behaviour,consisting of larger particles with faster settling velocities. | Raheleh Arabgol Peter A.Vanrolleghem Robert Delatolla | 2022 | Journal of Environmental Sciences2022，34，12： | 2 |
| 7 | SnCl_2/nano SiO_2: A green and reusable heterogeneous catalyst for the synthesis of polyfunctionalized 4H-pyrans显示文摘A highly effcient and general method for the synthesis of polyfunctionalized 4H-pyrans is established through a one-pot multicomponent cyclocondensation of aromatic aldehydes with CH acids,malononitrile and ethyl acetoacetate using nano silica supported tin(II) chloride as a catalyst. In this method SnCl2/nano SiO2was used as green and reusable catalyst. Excellent yields, short reaction times, simple workup, and inexpensiveness and commercially availability of the catalyst are the advantages of this method. | Javad Safaei-Ghomi Raheleh Teymuri Hossein Shahbazi-Alavi Abolfazl Ziarati | 2013 | Chinese Chemical Letters2013，24，10： | 2 |
| 8 | A machine learning approach to model solute grain boundary segregation显示文摘Even minute amounts of one solute atom per one million bulk atoms may give rise to qualitative changes in the mechanical response and fracture resistance of modern structural materials.These changes are commonly related to enrichment by several orders of magnitude of the solutes at structural defects in the host lattice.The underlying concept—segregation—is thus fundamental in materials science.To include it in modern strategies of materials design,accurate and realistic computational modelling tools are necessary.However,the enormous number of defect configurations as well as sites solutes can occupy requires models which rely on severe approximations.In the present study we combine a high-throughput study containing more than 1 million data points with machine learning to derive a computationally highly efficient framework which opens the opportunity to model this important mechanism on a routine basis. | Liam Huber Raheleh Hadian Blazej Grabowski Jörg Neugebauer | 2018 | npj Computational Materials2018，，1： | 2 |
| 9 | High entropy fluorides as conversion cathodes with tailorable electrochemical performance显示文摘With the recent development of high entropy materials, an alternative approach to develop advanced functional materials with distinctive properties that show improved values compared to conventional materials has been provided. The high entropy concept was later successfully transferred to metal fluorides and high entropy fluorides(HEFs) were successfully synthesized. Owing to their high theoretical specific capacities in energy storage applications, HEFs were utilized as cathode materials for lithiumion batteries(LIBs) and their underlying storage mechanisms were investigated. Instead of a step-bystep reduction of each individual metal cation, the HEFs seem to exhibit a single-step reduction process,indicating a solid solution compound instead of merely a mixture of different metal fluorides. It was also observed that the electrochemical behavior of the HEFs depends on each individual incorporated element. Therefore, by altering the elemental composition, new materials that exhibit improved electrochemical properties can be designed. Remarkably, HEFs with seven incorporated metal elements exhibited a better cycling stability as well as a lower hysteresis compared to binary metal fluorides.These findings offer new guidelines for material design and tailoring towards high performance LIBs. | Yanyan Cui Parvathy Anitha Sukkurji Kai Wang Raheleh Azmi Alexandra MNunn Horst Hahn Ben Breitung Yin-Ying Ting Piotr MKowalski Payam Kaghazchi Qingsong Wang Simon Schweidler Miriam Botros | 2022 | Journal of Energy Chemistry2022，31，9： | 2 |
| 10 | Texosome-based drug delivery system for cancer therapy: from past to present显示文摘Rising worldwide cancer incidence and resistance to current anti-cancer drugs necessitate the need for new pharmaceutical compounds and drug delivery system. Malfunction of the immune system, particularly in the tumor microenvironment, causes tumor growth and enhances tumor progression. Thus, cancer immunotherapy can be an appropriate approach to provoke the systemic immune system to combat tumor expansion. Texosomes, which are endogenous nanovesicles released by all tumor cells, contribute to cell-cell communication and modify the phenotypic features of recipient cells due to the texosomes' ability to transport biological components. For this reason, texosome-based delivery system can be a valuable strategy for therapeutic purposes. To improve the pharmaceutical behavior of this system and to facilitate its use in medical applications, biotechnology approaches and mimetic techniques have been utilized. In this review, we present the development history of texosome-based delivery systems and discuss the advantages and disadvantages of each system. | Hamideh Mahmoodzadeh Hosseini Raheleh Halabian Mohsen Amin Abbas Ali Imani Fooladi | 2015 | Cancer Biology & Medicine2015，12，3： | 2 |
| 11 | Ion-exchange process for ammonium removal and release using natural Iranian zeolite显示文摘 | Raheleh Malekian Jahangir Abedi-Koupai Sayed Saeid Eslamian | | 0，，03： | 1 |
| 12 | Nrf-2 overexpression in mesenchymal stem cells reduces oxidative stress-induced apoptosis and cytotoxicity显示文摘 | Mohammad Mohammadzadeh Raheleh Halabian Ahmad Gharehbaghian Naser Amirizadeh Ali Jahanian-Najafabadi Amaneh Roushandeh Mehryar Roudkenar | 2012 | Cell Stress and Chaperones2012，，5： | 1 |
| 13 | The Effect of Phytohormones on Lavender (Lavandula Angustiflia Mill.) Organogenesis显示文摘 | Tahmineh Sfandiyari sabzevar Raheleh Ahmadzadeh Ghavidel Setareh foroghian | 2015 | Journal of Pharmacy and Pharmacology2015，3，7： | 1 |
| 14 | Reliability-based simulation optimization model for multi-reservoir hydropower systems operations : khersan experience 显示文摘 | Raheleh A Seyed J M Abbas G | 2008 | Journal of Water Resources Planning and Management2008，134，1： | 1 |
| 15 | Ion-exchange process for ammonium removal and release using natural Iranian zeolite 显示文摘 | Raheleh Malekian Jahangir Abedi-Koupai Sayed Saeid Esiamian | 2011 | Applied Clay Science2011，51，3： | 1 |
| 16 | A novel field ionization gas sensor based on self-organized CuO nanowire arrays显示文摘 | Raheleh Mohammadpour Hassan Ahmadvand Azam Iraji zad | 2014 | Sensors & Actuators: A Physical2014，，： | 1 |
| 17 | Biological aplications of quantum dots 显示文摘 | Timothy Jamieson Raheleh Bakhshi Daniela Petrova | 2007 | Biomaterials2007，28，31： | 1 |
| 18 | Evaluation of hot corrosion behavior of plasma sprayed ceria and yttria stabilized zirconia thermal barrier coatings in the presence of Na2SO4+ V2O5 molten salt 显示文摘 | Raheleh Ahmadi-Pidani Reza Shoja-Razavi Reza Mozafarinia | 2012 | Ceramics International2012，38，： | 1 |
| 19 | Influences of clinoptilolite and surfactant-modi- fled clinoptilolite zeolite on nitrate leaching and plant growth显示文摘 | Raheleh Malekiana Jahangir Abedi-Koupai Sayed Saeid Eslamiana | 2011 | Journal of Hazardous Materials2011，185，： | 1 |
| 20 | Influences of clinoptilolite and surfactantmodifiedclinoptilolite zeolite on nitrate leaching and plant growth显示文摘 | RAHELEH MALEKIAN JAHANGIR ABEDI-KOUPAI SAYED SAEIDESLAMIAN | 2011 | Journal of Hazardous Materials2011，185，： | 1 |
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